Evidence for a role of IL-17 in organ allograft rejection: IL-17 promotes the functional differentiation of dendritic cell progenitors

Journal of Immunology

Volumn 162, Issue 1, 1999, Pages 577-584

  Antonysamy, Mary A ^a   Fanslow, William C ^c   Fu, Fumin ^a   Li, Wei ^a   Qian, Shiguang ^a   Troutt, Anthony B ^c   Thomson, Angus W ^a,b  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 17;

ALLOGRAFT; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; DENDRITIC CELL; GRAFT REJECTION; HEART TRANSPLANTATION; IMMUNOMODULATION; MALE; MOUSE; NONHUMAN; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; STEM CELL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CELL DIFFERENTIATION; CHORISTOMA; DENDRITIC CELLS; EAR, EXTERNAL; GRAFT REJECTION; HEART TRANSPLANTATION; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOPHENOTYPING; IMMUNOSUPPRESSIVE AGENTS; INTEGRIN ALPHAXBETA2; INTERLEUKIN-17; LYMPHOCYTE ACTIVATION; LYMPHOCYTE CULTURE TEST, MIXED; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED C57BL; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-17; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; STEM CELLS; T-LYMPHOCYTES; UP-REGULATION;

EID: 0032939561     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Rouvier, E., M.-F. Luciani, M.-G. Mattei, F. Denizot, and P. Golstein. 1993. CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene. J. Immunol. 150:5445.
2. Yao, Z., M. Timour, S. Painter, W. Fanslow, and M. Spriggs. 1996. Complete nucleotide sequence of the mouse CTLA8 gene. Gene 168:223.
3. Albrecht, J.-C., J. Nicholas, D. Biller, K. R. Cameron, B. Biesinger, C. Newman, S. Wittmann, M. A. Craxton, H. Coleman, B. Fleckenstein, et al. 1992. Primary structure of the herpesvirus saimiri genome. J. Virol. 66:5047.
4. Yao, Z., W. C. Fanslow, M. F. Seldin, A.-M. Rousseau, S. L. Painter, M. R. Comeau, J. I. Cohen, and M. K. Spriggs. 1995. Herpesvirus saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity 3:811.
5. Yao, Z., S. L. Painter, W. C. Fanslow, D. Ulrich, B. M. Macduff, M. K. Spriggs, and R. J. Armitage. 1995. Human IL-17: a novel cytokine derived from T cells. J. Immunol. 155:5483.
6. - T cells. J. Interferon Cytokine Res. 16:611.
7. Antonysamy, M. A., M. T. Lotze, H. Tahara, and A. W. Thomson. 1998. Interleukins 16, 17 and 18. In The Cytokine Handbook, 3rd Ed. A. W. Thomson, ed. Academic Press, San Diego, p. 465.
8. Yao, Z., M. K. Spriggs, J. M. J. Derry, L. Strockbine, L. S. Park, T. VandenBos, J. Zappone, S. L. Painter, and R. J. Armitage. 1997. Molecular characterization of the human interleukin (IL)-17 receptor. Cytokine 9:794.
9. Fossiez, F., O. Djossou, P. Chomarat, L. Flores-Romo, S. Ait-Yahia, C. Maat, J.-J. Pin, P. Garrone, E. Garcia, S. Saeland, et al. 1996. T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J. Exp. Med. 183:2593.
10. Jovanovic, D. V., J. A. Di Baltista, J. Martel-Pelletier, F. C. Jolicoeur, Y. He, M. Zhang, F. Mineau, and J.-P. Pelletier. 1998. IL-17 stimulates the production and expression of proinflammatory cytokines, IL-1β and TNF-α, by human macrophages. J. Immunol. 160:3513.
11. Chabaud, M., F. Fossiez, J.-L. Taupin, and P. Miossec. 1998. Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines. J. Immunol. 161:409.
12. Steinman, R. M. 1991. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 9:271.
13. Fulmer, R. I., A. T. Cramer, R. A. Liebelt, and A. G. Liebelt. 1963. Transplantation of cardiac tissue into the mouse ear. Am. J. Anat. 113:273.
14. Fanslow, W. C., J. E. Sims, H. Sassenfeld, P. J. Morrissey, S. Gillis, S. K. Dower, and M. B. Widmer. 1990. Regulation of alloreactivity in vivo by a soluble form of the interleukin-1 receptor. Science 248:739.
15. Ono, K., and E. S. Lindsay. 1968. Improved technique of heart transplantation in rats. J. Thorac. Cardiovasc. Surg. 57:225.
16. Inaba, K., M. Inaba, N. Romani, H. Aya, M. Deguchi, S. Ikehara, S. Muramatsu, and R. M. Steinman. 1992. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176:1693.
17. Lu, L., W. A. Rudert, S. Qian, D. McCaslin, F. Fu, A. S. Rao, M. Trucco, J. J. Fung, T. E. Starzl, and A. W. Thomson. 1995. Growth of donor-derived dendritic cells from the bone marrow of murine liver allograft recipients in response to granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 182: 379.
18. Austyn, J. M., D. F. Hankins, C. P. Larsen, P. J. Morris, A. S. Rao, and J. A. Roake. 1994. Isolation and characterization of dendritic cells from mouse heart and kidney. J. Immunol. 152:2401.
19. Woo, J., L. Lu, A. S. Rao, Y. Li, V. Subbotin, T. E. Starzl, and A. W. Thomson. 1994. Isolation, phenotype and allostimulatory activity of mouse liver dendritic cells. Transplantation 58:484.
20. Austyn, J. M. 1994. The initiation of immune responses and allograft rejection. In Immunology of Heart and Heart-Lung Transplantation. M. L. Rose and M. H. Yacoub, eds. Little, Brown & Co., Boston, p. 24.
21. Larsen C. P., P. J. Morris, and J. M. Austyn. 1990. Migration of dendritic leukocytes from cardiac allografts into host spleens, a novel pathway for initiation of rejection. J. Exp. Med. 171:307.
22. Thomson, A. W., L. Lu, V. M. Subbotin, Y. Li, S. Qian, A. S. Rao, J. J. Fung, and T. E. Starzl. 1995. In vitro propagation and homing of liver-derived dendritic cell progenitors to lymphoid tissues of allogeneic recipients. Transplantation 59: 544.
23. Halloran, P., T. Batiuk, and N. Goes. 1993. An overview of the cytokines in transplantation. Transplant Sci. 3:69.
24. Paul, L. C. 1993. Growth factors in chronic rejection. Transplant Sci. 3:113.
25. Kirkman, R. L., L. V. Barrett, G. N. Gaulton, V. E. Kelley, A. A. Ythier, and T. B. Strom. 1985. Administration of anti-interleukin-2 monoclonal antibody prolongs cardiac allograft survival in mice. J. Exp. Med. 162:358.
26. Kupiec-Weglinski, J. W., T. Sablinski, W. W. Hancock, T. B. Strom, and N. L. Tilney. 1991. Modulation of accelerated rejection of cardiac allografts in sensitized rats by anti-interleukin-2 receptor monoclonal antibody and cyclosporine therapy. Transplantation 51:300.
27. Imagawa, D. K., J. M. Millis, P. Seu, K. M. Olthoff, J. Hart, E. Wasef, R. A. Dempsey, S. Stephens, and R. W. Busuttil. 1991. The role of tumor necrosis factor in allograft rejection. III. Evidence that anti-TNF antibody therapy prolongs allograft survival in rats with acute rejection. Transplantation 51:57.
28. Landolfo, S., F. Cofano, M. Giovarelli, M. Prat, G. Cavallo, and G. Forni. 1985. Inhibition of interferon-γ may suppress allograft reactivity by T lymphocytes in vitro and in vivo. Science 229:176.
29. Maliszewski, C. R., P. J. Morrissey, W. C. Fanslow, T. A. Sato, C. Willis, and B. Davison. 1992. Delayed allograft rejection in mice transgenic for a soluble form of the IL-4 receptor. Cell. Immunol. 143:434.
30. Williamson, E., P. Garside, J. A. Bradley, I. A. R. More, and A. M. Mowat. 1997. Neutralizing IL-12 during induction of murine acute graft-versus-host disease polarizes the cytokine profile toward a Th2-type alloimmune response and confers long term protection from disease. J. Immunol. 159:1208.
31. Pugh-Humphreys, R. G. P., and A. W. Thomson. 1998. Cytokines and their receptors as potential therapeutic targets. In The Cytokine Handbook, 3rd Ed. A. W. Thomson, ed. Academic Press, San Diego, p. 885.
32. Spriggs, M. 1997. Interleukin-17 and its receptor. J. Clin. Immunol. 17:366.
33. Lotz, M., L. Bober, S. Narula, and J. Dudler. 1996. IL-17 promotes cartilage degradation. Arthritis Rheum. 39(Suppl.):S120.
34. Dallman, M. J. 1993. Cytokines as mediators of organ graft rejection and tolerance. Curr. Opin. Immunol. 5:788.
35. Dallman, M. J. 1996. Cytokines. In Transplantation Biology: Cellular and Molecular Aspects. N. L. Tilney, T. B. Strom, and L. C. Paul, eds. Lippincott-Raven, Philadelphia, p. 201.