메뉴 건너뛰기




Volumn 35, Issue 6, 2009, Pages 1036-1044

Modalities and future prospects of gene therapy in heart transplantation

Author keywords

Gene therapy; Graft vasculopathy; Heart transplantation; Rejection; Tolerance

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; FAS ANTIGEN; FAS LIGAND; GELATINASE A; HEME OXYGENASE 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN BCL 2; PROTEIN BCL X; TISSUE PLASMINOGEN ACTIVATOR;

EID: 67349235533     PISSN: 10107940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejcts.2009.01.044     Document Type: Review
Times cited : (9)

References (75)
  • 1
    • 38949106584 scopus 로고    scopus 로고
    • Outcomes in patients older than 60 years of age undergoing orthotopic heart transplantation: an analysis of the UNOS database
    • Weiss E.S., Nwakanma L.U., Patel N.D., and Yuh D.D. Outcomes in patients older than 60 years of age undergoing orthotopic heart transplantation: an analysis of the UNOS database. J Heart Lung Transplant 27 (2008) 184-191
    • (2008) J Heart Lung Transplant , vol.27 , pp. 184-191
    • Weiss, E.S.1    Nwakanma, L.U.2    Patel, N.D.3    Yuh, D.D.4
  • 2
    • 0042885512 scopus 로고    scopus 로고
    • Adeno-associated virus (AAV) vectors achieve prolonged transgene expression in mouse myocardium and arteries in vivo: a comparative study with adenovirus vectors
    • Vassalli G., Büeler H., Dudler J., von Seegsser L.K., and Kappenberger L. Adeno-associated virus (AAV) vectors achieve prolonged transgene expression in mouse myocardium and arteries in vivo: a comparative study with adenovirus vectors. Int J Cardiol 90 (2003) 229-238
    • (2003) Int J Cardiol , vol.90 , pp. 229-238
    • Vassalli, G.1    Büeler, H.2    Dudler, J.3    von Seegsser, L.K.4    Kappenberger, L.5
  • 3
    • 51049087302 scopus 로고    scopus 로고
    • Progress and prospects: genetic engineering in xenotransplantation
    • Le Bas-Bernardet S., Anegon I., and Blancho G. Progress and prospects: genetic engineering in xenotransplantation. Gene Ther 15 (2008) 1247-1256
    • (2008) Gene Ther , vol.15 , pp. 1247-1256
    • Le Bas-Bernardet, S.1    Anegon, I.2    Blancho, G.3
  • 4
    • 3142680351 scopus 로고    scopus 로고
    • Helper-dependent adenovirus vectors devoid of all viral genes cause less myocardial inflammation compared with first-generation adenovirus vectors
    • Fleury S., Driscoll R.A., Simeoni E., Dudler J., von Segesser L.K., Kappenberger L., and Vassalli G. Helper-dependent adenovirus vectors devoid of all viral genes cause less myocardial inflammation compared with first-generation adenovirus vectors. Basic Res Cardiol 99 (2004) 247-256
    • (2004) Basic Res Cardiol , vol.99 , pp. 247-256
    • Fleury, S.1    Driscoll, R.A.2    Simeoni, E.3    Dudler, J.4    von Segesser, L.K.5    Kappenberger, L.6    Vassalli, G.7
  • 5
    • 33645064807 scopus 로고    scopus 로고
    • Improved cardiac gene transfer by transcriptional and transductional targeting of adeno-associated viral vectors
    • Müller O.J., Leuchs B., Pleger S.T., Grimm D., Franz W.M., Katus H.A., and Kleinschmidt J.A. Improved cardiac gene transfer by transcriptional and transductional targeting of adeno-associated viral vectors. Cardiovasc Res 70 (2006) 70-78
    • (2006) Cardiovasc Res , vol.70 , pp. 70-78
    • Müller, O.J.1    Leuchs, B.2    Pleger, S.T.3    Grimm, D.4    Franz, W.M.5    Katus, H.A.6    Kleinschmidt, J.A.7
  • 7
    • 0038663005 scopus 로고    scopus 로고
    • Multiply attenuated, self-inactivating lentiviral vectors efficiently deliver and express genes for extended periods of time in adult rat cardiomyocytes in vivo
    • Fleury S., Simeoni E., Zuppinger C., Déglon N., von Segesser L.K., Kappenberger L., and Vassalli G. Multiply attenuated, self-inactivating lentiviral vectors efficiently deliver and express genes for extended periods of time in adult rat cardiomyocytes in vivo. Circulation 107 (2003) 2375-2382
    • (2003) Circulation , vol.107 , pp. 2375-2382
    • Fleury, S.1    Simeoni, E.2    Zuppinger, C.3    Déglon, N.4    von Segesser, L.K.5    Kappenberger, L.6    Vassalli, G.7
  • 8
    • 13444302633 scopus 로고    scopus 로고
    • Multiply attenuated, self-inactivating lentiviral vectors efficiently transduce human coronary artery cells in vitro and rat arteries in vivo
    • Cefaï D., Simeoni E., Ludunge K.M., Driscoll R., von Segesser L.K., Kappenberger L., and Vassalli G. Multiply attenuated, self-inactivating lentiviral vectors efficiently transduce human coronary artery cells in vitro and rat arteries in vivo. J Mol Cell Cardiol 38 (2005) 333-344
    • (2005) J Mol Cell Cardiol , vol.38 , pp. 333-344
    • Cefaï, D.1    Simeoni, E.2    Ludunge, K.M.3    Driscoll, R.4    von Segesser, L.K.5    Kappenberger, L.6    Vassalli, G.7
  • 9
    • 33644849955 scopus 로고    scopus 로고
    • Lentiviral gene transfer of the chemokine antagonist RANTES 9-68 prolongs heart graft survival
    • Vassalli G., Simeoni E., Li J., and Fleury S. Lentiviral gene transfer of the chemokine antagonist RANTES 9-68 prolongs heart graft survival. Transplantation 81 (2006) 240-246
    • (2006) Transplantation , vol.81 , pp. 240-246
    • Vassalli, G.1    Simeoni, E.2    Li, J.3    Fleury, S.4
  • 10
    • 0034669333 scopus 로고    scopus 로고
    • DNA-liposome versus adenoviral mediated gene transfer of transforming growth factor beta1 in vascularized cardiac allografts: differential sensitivity of CD4+ and CD8+ T cells to transforming growth factor beta1
    • Chan S.Y., Goodman R.E., Szmuszkovicz J.R., Roessler B., Eichwald E.J., and Bishop D.K. DNA-liposome versus adenoviral mediated gene transfer of transforming growth factor beta1 in vascularized cardiac allografts: differential sensitivity of CD4+ and CD8+ T cells to transforming growth factor beta1. Transplantation 70 (2000) 1292-1304
    • (2000) Transplantation , vol.70 , pp. 1292-1304
    • Chan, S.Y.1    Goodman, R.E.2    Szmuszkovicz, J.R.3    Roessler, B.4    Eichwald, E.J.5    Bishop, D.K.6
  • 11
    • 0036846830 scopus 로고    scopus 로고
    • Localized immunosuppression in the cardiac allograft induced by a new liposome-mediated IL-10 gene therapy
    • Hong Y.S., Laks H., Cui G., Chong T., and Sen L. Localized immunosuppression in the cardiac allograft induced by a new liposome-mediated IL-10 gene therapy. J Heart Lung Transplant 21 (2002) 1188-1200
    • (2002) J Heart Lung Transplant , vol.21 , pp. 1188-1200
    • Hong, Y.S.1    Laks, H.2    Cui, G.3    Chong, T.4    Sen, L.5
  • 13
    • 52049110535 scopus 로고    scopus 로고
    • Advances in non-viral gene delivery: using multifunctional envelope-type nano-devices
    • Akita H., and Harashima G. Advances in non-viral gene delivery: using multifunctional envelope-type nano-devices. Expert Opin Drug Deliv 5 (2008) 847-859
    • (2008) Expert Opin Drug Deliv , vol.5 , pp. 847-859
    • Akita, H.1    Harashima, G.2
  • 14
    • 0033610244 scopus 로고    scopus 로고
    • Antisense oligodeoxynucleotides prevent acute cardiac allograft rejection via a novel, nontoxic, highly efficient transfection method
    • Poston R.S., Mann M.J., Hoyt E.G., Ennen M., Dzau V.J., and Robbins R.C. Antisense oligodeoxynucleotides prevent acute cardiac allograft rejection via a novel, nontoxic, highly efficient transfection method. Transplantation 68 (1999) 825-832
    • (1999) Transplantation , vol.68 , pp. 825-832
    • Poston, R.S.1    Mann, M.J.2    Hoyt, E.G.3    Ennen, M.4    Dzau, V.J.5    Robbins, R.C.6
  • 15
    • 0035810917 scopus 로고    scopus 로고
    • Liposome-mediated gene transfection of endothelial nitric oxide synthase reduces endothelial activation and leukocyte infiltration in transplanted hearts
    • Iwata A., Sai S., Nitta Y., Chen M., deFries-Hallstrand R., Dalesandro J., Thomas R., and Allen M.D. Liposome-mediated gene transfection of endothelial nitric oxide synthase reduces endothelial activation and leukocyte infiltration in transplanted hearts. Circulation 103 (2001) 2753-2759
    • (2001) Circulation , vol.103 , pp. 2753-2759
    • Iwata, A.1    Sai, S.2    Nitta, Y.3    Chen, M.4    deFries-Hallstrand, R.5    Dalesandro, J.6    Thomas, R.7    Allen, M.D.8
  • 16
    • 0038526269 scopus 로고    scopus 로고
    • Multigene adenoviral therapy for the attenuation of ischemia-reperfusion injury after preservation for cardiac transplantation
    • Abunasra H.J., Smolenski R.T., Yap J., Sheppard M., O'Brien T., and Yacoub M.H. Multigene adenoviral therapy for the attenuation of ischemia-reperfusion injury after preservation for cardiac transplantation. J Thorac Cardiovasc Surg 125 (2003) 998-1006
    • (2003) J Thorac Cardiovasc Surg , vol.125 , pp. 998-1006
    • Abunasra, H.J.1    Smolenski, R.T.2    Yap, J.3    Sheppard, M.4    O'Brien, T.5    Yacoub, M.H.6
  • 17
    • 41149177025 scopus 로고    scopus 로고
    • Pharmacological and clinical aspects of heme oxygenase
    • Erratum in: Pharmacol Rev 2008;60:242
    • Abraham N.G., and Kappas A. Pharmacological and clinical aspects of heme oxygenase. Pharmacol Rev 60 (2008) 79-127 Erratum in: Pharmacol Rev 2008;60:242
    • (2008) Pharmacol Rev , vol.60 , pp. 79-127
    • Abraham, N.G.1    Kappas, A.2
  • 19
    • 0035908946 scopus 로고    scopus 로고
    • Overexpression of interleukin-1 receptor antagonist provides cardioprotection against ischemia-reperfusion injury associated with reduction in apoptosis
    • Suzuki K., Murtuza B., Smolenski R.T., Sammut I.A., Suzuki N., Kaneda Y., and Yacoub M.H. Overexpression of interleukin-1 receptor antagonist provides cardioprotection against ischemia-reperfusion injury associated with reduction in apoptosis. Circulation 104 Suppl. 1 (2001) I308-I313
    • (2001) Circulation , vol.104 , Issue.SUPPL. 1
    • Suzuki, K.1    Murtuza, B.2    Smolenski, R.T.3    Sammut, I.A.4    Suzuki, N.5    Kaneda, Y.6    Yacoub, M.H.7
  • 21
    • 0033914386 scopus 로고    scopus 로고
    • Ischemia/reperfusion injury-mediated down-regulation of adenovirus-mediated gene expression in a rat heart transplantation model is inhibited by co-application of a TNFRp55-Ig chimeric construct
    • Ritter T., Schroder G., Risch K., Vergopoulos A., Shean M.K., Kolls J., Brock J., Lehmann M., and Volk H.D. Ischemia/reperfusion injury-mediated down-regulation of adenovirus-mediated gene expression in a rat heart transplantation model is inhibited by co-application of a TNFRp55-Ig chimeric construct. Gene Ther 7 (2000) 1238-1243
    • (2000) Gene Ther , vol.7 , pp. 1238-1243
    • Ritter, T.1    Schroder, G.2    Risch, K.3    Vergopoulos, A.4    Shean, M.K.5    Kolls, J.6    Brock, J.7    Lehmann, M.8    Volk, H.D.9
  • 27
    • 0034120177 scopus 로고    scopus 로고
    • Regulatory cells potentiate the efficacy of IL-4 gene transfer by up-regulating Th2-dependent expression of protective molecules in the infectious tolerance pathway in transplant recipients
    • Ke B., Ritter T., Kato H., Zhai Y., Li J., Lehmann M., Busuttil R.W., Volk H.D., and Kupiec-Weglinski J.W. Regulatory cells potentiate the efficacy of IL-4 gene transfer by up-regulating Th2-dependent expression of protective molecules in the infectious tolerance pathway in transplant recipients. J Immunol 164 (2000) 5739-5745
    • (2000) J Immunol , vol.164 , pp. 5739-5745
    • Ke, B.1    Ritter, T.2    Kato, H.3    Zhai, Y.4    Li, J.5    Lehmann, M.6    Busuttil, R.W.7    Volk, H.D.8    Kupiec-Weglinski, J.W.9
  • 28
    • 0036414453 scopus 로고    scopus 로고
    • Heme oxygenase 1 mediates the immunomodulatory and antiapoptotic effects of interleukin 13 gene therapy in vivo and in vitro
    • Ke B., Shen X.D., Zhai Y., Gao F., Busuttil R.W., Volk H.D., and Kupiec-Weglinski J.W. Heme oxygenase 1 mediates the immunomodulatory and antiapoptotic effects of interleukin 13 gene therapy in vivo and in vitro. Hum Gene Ther 13 (2002) 1845-1857
    • (2002) Hum Gene Ther , vol.13 , pp. 1845-1857
    • Ke, B.1    Shen, X.D.2    Zhai, Y.3    Gao, F.4    Busuttil, R.W.5    Volk, H.D.6    Kupiec-Weglinski, J.W.7
  • 29
    • 18944400713 scopus 로고    scopus 로고
    • Liposome-mediated combinatorial cytokine gene therapy induces localized synergistic immunosuppression and promotes long-term survival of cardiac allografts
    • Furukawa H., Oshima K., Tung T., Cui G., Laks H., and Sen L. Liposome-mediated combinatorial cytokine gene therapy induces localized synergistic immunosuppression and promotes long-term survival of cardiac allografts. J Immunol 174 (2005) 6983-6992
    • (2005) J Immunol , vol.174 , pp. 6983-6992
    • Furukawa, H.1    Oshima, K.2    Tung, T.3    Cui, G.4    Laks, H.5    Sen, L.6
  • 32
    • 0034066276 scopus 로고    scopus 로고
    • Gene transfer of virally encoded chemokine antagonists vMIP-II and MC148 prolongs cardiac allograft survival and inhibits donor-specific immunity
    • DeBruyne L.A., Li K., Bishop D.K., and Bromberg J.S. Gene transfer of virally encoded chemokine antagonists vMIP-II and MC148 prolongs cardiac allograft survival and inhibits donor-specific immunity. Gene Ther 7 (2000) 575-582
    • (2000) Gene Ther , vol.7 , pp. 575-582
    • DeBruyne, L.A.1    Li, K.2    Bishop, D.K.3    Bromberg, J.S.4
  • 33
    • 0032543306 scopus 로고    scopus 로고
    • The role of T-cell costimulatory activation pathways in transplant rejection
    • Sayegh M.H., and Turka L.A. The role of T-cell costimulatory activation pathways in transplant rejection. N Engl J Med 338 (1998) 1813-1821
    • (1998) N Engl J Med , vol.338 , pp. 1813-1821
    • Sayegh, M.H.1    Turka, L.A.2
  • 35
    • 0037083278 scopus 로고    scopus 로고
    • Prolonged blockade of CD40-CD40 ligand interactions by gene transfer of CD40Ig results in long-term heart allograft survival and donor-specific hyporesponsiveness, but does not prevent chronic rejection
    • Guillot C., Guillonneau C., Mathieu P., Gerder C.A., Ménoret S., Braudeau C., Tesson L., Renaudin K., Castro M.G., Löwenstein P.R., and Anegon I. Prolonged blockade of CD40-CD40 ligand interactions by gene transfer of CD40Ig results in long-term heart allograft survival and donor-specific hyporesponsiveness, but does not prevent chronic rejection. J Immunol 168 (2002) 1600-1609
    • (2002) J Immunol , vol.168 , pp. 1600-1609
    • Guillot, C.1    Guillonneau, C.2    Mathieu, P.3    Gerder, C.A.4    Ménoret, S.5    Braudeau, C.6    Tesson, L.7    Renaudin, K.8    Castro, M.G.9    Löwenstein, P.R.10    Anegon, I.11
  • 40
    • 33845919184 scopus 로고    scopus 로고
    • Gene transfer of programmed death ligand-1.Ig prolongs cardiac allograft survival
    • Dudler J., Li J., Pagnotta M., von Segesser L.K., and Vassalli G. Gene transfer of programmed death ligand-1.Ig prolongs cardiac allograft survival. Transplantation 82 (2006) 1733-1737
    • (2006) Transplantation , vol.82 , pp. 1733-1737
    • Dudler, J.1    Li, J.2    Pagnotta, M.3    von Segesser, L.K.4    Vassalli, G.5
  • 41
    • 0038404817 scopus 로고    scopus 로고
    • Gene therapy in organ transplantation
    • Bagley J., and Jacomini J. Gene therapy in organ transplantation. Gene Ther 10 (2003) 605-611
    • (2003) Gene Ther , vol.10 , pp. 605-611
    • Bagley, J.1    Jacomini, J.2
  • 42
    • 0023865253 scopus 로고
    • Immunological unresponsiveness induced by recipient cells transfected with donor MHC genes
    • Madsen J.C., Superina R.A., Wood K.J., and Morris P.J. Immunological unresponsiveness induced by recipient cells transfected with donor MHC genes. Nature 331 (1988) 161-164
    • (1988) Nature , vol.331 , pp. 161-164
    • Madsen, J.C.1    Superina, R.A.2    Wood, K.J.3    Morris, P.J.4
  • 43
    • 0030903907 scopus 로고    scopus 로고
    • Retroviral gene transfer of a class I MHC gene to recipient bone marrow induces tolerance to alloantigens in vivo
    • Wong W., Stranford S.A., Morris P.J., and Wood K.J. Retroviral gene transfer of a class I MHC gene to recipient bone marrow induces tolerance to alloantigens in vivo. Transplant Proc 29 (1997) 1130
    • (1997) Transplant Proc , vol.29 , pp. 1130
    • Wong, W.1    Stranford, S.A.2    Morris, P.J.3    Wood, K.J.4
  • 44
    • 0036190812 scopus 로고    scopus 로고
    • Adenoviral transfer of a single donor-specific MHC class I gene to recipient bone marrow cells can induce specific immunological unresponsiveness in vivo
    • Fry J.W., Morris P.J., and Wood K.J. Adenoviral transfer of a single donor-specific MHC class I gene to recipient bone marrow cells can induce specific immunological unresponsiveness in vivo. Gene Ther 9 (2002) 220-226
    • (2002) Gene Ther , vol.9 , pp. 220-226
    • Fry, J.W.1    Morris, P.J.2    Wood, K.J.3
  • 46
    • 0037097841 scopus 로고    scopus 로고
    • Induction of T-cell tolerance to an MHC class I alloantigen by gene therapy
    • Bagley J., Tian C., Sachs D.H., and Iacomini J. Induction of T-cell tolerance to an MHC class I alloantigen by gene therapy. Blood 99 (2002) 4394-4399
    • (2002) Blood , vol.99 , pp. 4394-4399
    • Bagley, J.1    Tian, C.2    Sachs, D.H.3    Iacomini, J.4
  • 47
    • 17544386950 scopus 로고    scopus 로고
    • Establishing immunological tolerance through the induction of molecular chimerism
    • Bagley J., Bracy J.L., Tian C., Kang E.S., and Iacomini J. Establishing immunological tolerance through the induction of molecular chimerism. Front Biosci 7 (2002) 1331-1337
    • (2002) Front Biosci , vol.7 , pp. 1331-1337
    • Bagley, J.1    Bracy, J.L.2    Tian, C.3    Kang, E.S.4    Iacomini, J.5
  • 48
    • 14844352743 scopus 로고    scopus 로고
    • CD25+ CD4+ regulatory T cells generated by exposure to a model protein antigen prevent allograft rejection: antigen specific reactivation in vivo is critical for bystander regulation
    • Karim M., Feng G., Wood K., and Bushell A. CD25+ CD4+ regulatory T cells generated by exposure to a model protein antigen prevent allograft rejection: antigen specific reactivation in vivo is critical for bystander regulation. Blood 105 (2005) 4871-4877
    • (2005) Blood , vol.105 , pp. 4871-4877
    • Karim, M.1    Feng, G.2    Wood, K.3    Bushell, A.4
  • 52
    • 33646708077 scopus 로고    scopus 로고
    • Avenues for immunomodulation and graft protection by gene therapy in transplantation
    • Moore D., Markmann J., and Deng S. Avenues for immunomodulation and graft protection by gene therapy in transplantation. Transplant Int 19 (2006) 435-445
    • (2006) Transplant Int , vol.19 , pp. 435-445
    • Moore, D.1    Markmann, J.2    Deng, S.3
  • 53
    • 33746342782 scopus 로고    scopus 로고
    • Infectious tolerance and the long-term acceptance of transplanted tissue
    • Waldmann H., Adams E., Fairchild P., and Cobbold S. Infectious tolerance and the long-term acceptance of transplanted tissue. Immunol Rev 212 (2006) 301-313
    • (2006) Immunol Rev , vol.212 , pp. 301-313
    • Waldmann, H.1    Adams, E.2    Fairchild, P.3    Cobbold, S.4
  • 54
    • 0038606015 scopus 로고    scopus 로고
    • Alloimmunity and nonimmunologic risk factors in cardiac allograft vasculopathy
    • Working Group Microcirculation of the European Society of Cardiology
    • Vassalli G., Gallino A., Weis M., von Scheidt W., Kappenberger L., von Segesser L.K., Goy J.J., and Working Group Microcirculation of the European Society of Cardiology. Alloimmunity and nonimmunologic risk factors in cardiac allograft vasculopathy. Eur Heart J 24 (2003) 1180-1188
    • (2003) Eur Heart J , vol.24 , pp. 1180-1188
    • Vassalli, G.1    Gallino, A.2    Weis, M.3    von Scheidt, W.4    Kappenberger, L.5    von Segesser, L.K.6    Goy, J.J.7
  • 57
    • 0033955856 scopus 로고    scopus 로고
    • Antisense Bcl-x oligonucleotide induces apoptosis and prevents arterial neointimal formation in murine cardiac allografts
    • Suzuki J., Isobe M., Morishita R., Nishikawa T., Amano J., and Kaneda Y. Antisense Bcl-x oligonucleotide induces apoptosis and prevents arterial neointimal formation in murine cardiac allografts. Cardiovasc Res 45 (2000) 783-787
    • (2000) Cardiovasc Res , vol.45 , pp. 783-787
    • Suzuki, J.1    Isobe, M.2    Morishita, R.3    Nishikawa, T.4    Amano, J.5    Kaneda, Y.6
  • 58
    • 0043269207 scopus 로고    scopus 로고
    • Effects of adenoviral up-regulation of bcl-2 on oxidative stress and graft coronary artery disease in rat heart transplants
    • Miniati D., Lijkwan M., Murata S., Martens J., Coleman C.T., Hoyt E.G., and Robbins R.C. Effects of adenoviral up-regulation of bcl-2 on oxidative stress and graft coronary artery disease in rat heart transplants. Transplantation 76 (2003) 382-386
    • (2003) Transplantation , vol.76 , pp. 382-386
    • Miniati, D.1    Lijkwan, M.2    Murata, S.3    Martens, J.4    Coleman, C.T.5    Hoyt, E.G.6    Robbins, R.C.7
  • 59
    • 0036261451 scopus 로고    scopus 로고
    • Adenovirus-mediated CD40Ig expression attenuates chronic vascular rejection lesions in an aorta allotransplantation model
    • Mathieu P., Guillot C., Gerdes C., Buzelin F., Lowenstein P., Castro M., Soulillou J.P., and Anegon I. Adenovirus-mediated CD40Ig expression attenuates chronic vascular rejection lesions in an aorta allotransplantation model. Transplant Proc 34 (2002) 743-744
    • (2002) Transplant Proc , vol.34 , pp. 743-744
    • Mathieu, P.1    Guillot, C.2    Gerdes, C.3    Buzelin, F.4    Lowenstein, P.5    Castro, M.6    Soulillou, J.P.7    Anegon, I.8
  • 61
    • 0343773374 scopus 로고    scopus 로고
    • Fas ligand overexpression on allograft endothelium inhibits inflammatory cell infiltration and transplant-associated intimal hyperplasia
    • Sata M., Luo Z., and Walsh K. Fas ligand overexpression on allograft endothelium inhibits inflammatory cell infiltration and transplant-associated intimal hyperplasia. J Immunol 166 (2001) 6964-6971
    • (2001) J Immunol , vol.166 , pp. 6964-6971
    • Sata, M.1    Luo, Z.2    Walsh, K.3
  • 63
    • 33845457603 scopus 로고    scopus 로고
    • Antisense ERK1/2 oligodeoxynucleotide gene therapy attenuates graft arteriosclerosis of aortic transplant in a rat model
    • Dong C., Gong N., Chen Z., Chen X., Xu Q., Guo H., Zeng Z., Ming C., and Chen Z.K. Antisense ERK1/2 oligodeoxynucleotide gene therapy attenuates graft arteriosclerosis of aortic transplant in a rat model. Transplant Proc 38 (2006) 3304-3306
    • (2006) Transplant Proc , vol.38 , pp. 3304-3306
    • Dong, C.1    Gong, N.2    Chen, Z.3    Chen, X.4    Xu, Q.5    Guo, H.6    Zeng, Z.7    Ming, C.8    Chen, Z.K.9
  • 64
    • 21844468741 scopus 로고    scopus 로고
    • CTLA4-Fas ligand gene transfer mediated by adenovirus induce long-time survival of murine cardiac allografts
    • Feng Y., Jin Y., Zhang Q., Hao J., Wang G., and Xie S. CTLA4-Fas ligand gene transfer mediated by adenovirus induce long-time survival of murine cardiac allografts. Transplant Proc 37 (2005) 2379-2381
    • (2005) Transplant Proc , vol.37 , pp. 2379-2381
    • Feng, Y.1    Jin, Y.2    Zhang, Q.3    Hao, J.4    Wang, G.5    Xie, S.6
  • 66
    • 0036890477 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases in cardiac allograft vasculopathy and its attenuation by anti MMP-2 ribozyme gene transfection
    • Tsukioka K., Suzuki J., Fujimori M., Wada Y., Yamaura K., Ito K., Morishita R., Kaneda Y., Isobe M., and Amano J. Expression of matrix metalloproteinases in cardiac allograft vasculopathy and its attenuation by anti MMP-2 ribozyme gene transfection. Cardiovasc Res 56 (2002) 472-478
    • (2002) Cardiovasc Res , vol.56 , pp. 472-478
    • Tsukioka, K.1    Suzuki, J.2    Fujimori, M.3    Wada, Y.4    Yamaura, K.5    Ito, K.6    Morishita, R.7    Kaneda, Y.8    Isobe, M.9    Amano, J.10
  • 67
    • 34250183841 scopus 로고    scopus 로고
    • Development of ribozyme-based gene inactivations; the example of the hepatitis delta virus ribozyme
    • Asif-Ullah M., Lévesque M., Robichaud G., and Perreault J.P. Development of ribozyme-based gene inactivations; the example of the hepatitis delta virus ribozyme. Curr Gene Ther 7 (2007) 205-216
    • (2007) Curr Gene Ther , vol.7 , pp. 205-216
    • Asif-Ullah, M.1    Lévesque, M.2    Robichaud, G.3    Perreault, J.P.4
  • 68
    • 0034711518 scopus 로고    scopus 로고
    • Gene therapy for attenuating cardiac allograft vasculopathy using ex vivo E2F decoy transfection by HVJ-AVE-liposome method in mice and nonhuman primates
    • Kawauchi M., Suzuki J., Morishita R., Wada Y., Izawa A., Tomita N., Amano J., Kaneda Y., Ogihara T., Takamoto S., and Isobe M. Gene therapy for attenuating cardiac allograft vasculopathy using ex vivo E2F decoy transfection by HVJ-AVE-liposome method in mice and nonhuman primates. Circ Res 87 (2000) 1063-1068
    • (2000) Circ Res , vol.87 , pp. 1063-1068
    • Kawauchi, M.1    Suzuki, J.2    Morishita, R.3    Wada, Y.4    Izawa, A.5    Tomita, N.6    Amano, J.7    Kaneda, Y.8    Ogihara, T.9    Takamoto, S.10    Isobe, M.11
  • 69
    • 0037303466 scopus 로고    scopus 로고
    • A voluntary moratorium?
    • Verma I.M. A voluntary moratorium?. Mol Ther 7 (2003) 141
    • (2003) Mol Ther , vol.7 , pp. 141
    • Verma, I.M.1
  • 71
    • 0034794768 scopus 로고    scopus 로고
    • Challenges to achieving clinical transplantation tolerance
    • Salama A.D., Remuzzi G., Harmon W.E., and Sayegh M.H. Challenges to achieving clinical transplantation tolerance. J Clin Invest 108 (2001) 943-948
    • (2001) J Clin Invest , vol.108 , pp. 943-948
    • Salama, A.D.1    Remuzzi, G.2    Harmon, W.E.3    Sayegh, M.H.4
  • 72
    • 0041806502 scopus 로고    scopus 로고
    • Looking into the safety of AAV vectors
    • Kay M.A., and Nakai H. Looking into the safety of AAV vectors. Nature 424 (2003) 251
    • (2003) Nature , vol.424 , pp. 251
    • Kay, M.A.1    Nakai, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.