Multiply attenuated, self-inactivating lentiviral vectors efficiently deliver and express genes for extended periods of time in adult rat cardiomyocytes in vivo

Circulation

Volumn 107, Issue 18, 2003, Pages 2375-2382

  Fleury, Sylvain ^a   Simeoni, Eleonora ^a   Zuppinger, Christian ^c   Déglon, Nicole ^b   Von Segesser, Ludwig K ^a   Kappenberger, Lukas ^a   Vassalli, Giuseppe ^a,d  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b EPFL   (Switzerland)

^c UNIVERSITY OF BERN   (Switzerland)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Gene therapy; Myocardium; Viruses

Indexed keywords

ADENOVIRUS VECTOR; ELONGATION FACTOR 1ALPHA; GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; PHOSPHOGLYCERATE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS; ENHANCER REGION; GENE THERAPY; HEART MUSCLE CELL; IN VIVO STUDY; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; RAT; SIGNAL TRANSDUCTION; TIME SERIES ANALYSIS; TRANSCRIPTION REGULATION; VIRAL GENE DELIVERY SYSTEM; VIRUS INACTIVATION;

ADENOVIRIDAE; ANIMALS; BASE SEQUENCE; CELLS, CULTURED; DNA, VIRAL; GENE EXPRESSION; GENETIC VECTORS; KINETICS; LENTIVIRUS; MALE; MYOCARDITIS; MYOCYTES, CARDIAC; PURINES; RATS; RATS, WISTAR; TRANSDUCTION, GENETIC; TRANSGENES; VIRUS INACTIVATION;

EID: 0038663005     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000065598.46411.EF     Document Type: Article

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