Differential regulation of glutamate-cysteine ligase subunit expression and increased holoenzyme formation in response to cysteine deprivation

Biochemical Journal

Volumn 393, Issue 1, 2006, Pages 181-190

  Lee, Jeong In ^a   Kang, Joann ^a   Stipanuk, Martha H ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

Cysteine; Glutamate cysteine ligase (GCL); Glutathione (GSH); HepG2 C3A cells; Holoenzyme; Low protein diet

Indexed keywords

AMINO ACIDS; CATALYSIS; CELLS; DIMERS; SULFUR;

CYSTEINE; GLUTAMATE-CYSTEINE LIGASE (GCL); GLUTATHIONE (GSH); HEPG2/C3A CELLS; HOLOENZYME; LOW-PROTEIN DIET;

ENZYMES;

COMPLEMENTARY DNA; CYSTEINE; DICHLORODIHYDROFLUORESCEIN DIACETATE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; HOLOENZYME; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; SULFUR AMINO ACID; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATALYSIS; CELL STRAIN HEPG2; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME SUBUNIT; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL; MALE; NONHUMAN; NORTHERN BLOTTING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN RESTRICTION; RAT; WESTERN BLOTTING;

ANIMALS; CATALYTIC DOMAIN; CELL LINE, TUMOR; CYSTEINE; DIETARY PROTEINS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HOLOENZYMES; HUMANS; LIVER; MALE; PROTEIN SUBUNITS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

ANIMALIA;

EID: 30044452581     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20051111     Document Type: Article

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