Acetaminophen-induced liver injury is attenuated in male glutamate-cysteine ligase transgenic mice

Journal of Biological Chemistry

Volumn 281, Issue 39, 2006, Pages 28865-28875

  Botta, Dianne ^a   Shi, Shengli ^a,c   White, Collin C ^a   Dabrowski, Michael J ^a   Keener, Cassie L ^a   Srinouanprachanh, Sengkeo L ^a   Farin, Federico M ^a   Ware, Carol B ^a   Ladiges, Warren C ^a   Pierce, Robert H ^a   Fausto, Nelson ^b   Kavanagh, Terrance J ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAMINOPHEN; ENZYMATIC REACTIONS; LIGASE; LIVER FAILURE;

ANTIOXIDANTS; BIOCHEMISTRY; BIOTECHNOLOGY; CELL CULTURE; DRUG THERAPY; ENZYMES; OXIDATION; PATHOLOGY;

BIODIVERSITY;

ALANINE AMINOTRANSFERASE; GLUTAMATE CYSTEINE LIGASE; MIFEPRISTONE; PARACETAMOL;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; GENE OVEREXPRESSION; GLUTATHIONE METABOLISM; HETEROZYGOTE; HISTOPATHOLOGY; LIVER INJURY; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE;

ACETAMINOPHEN; ALANINE TRANSAMINASE; ANIMALS; ANTIOXIDANTS; GLUTAMATE-CYSTEINE LIGASE; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MIFEPRISTONE; MODELS, GENETIC; OXIDATIVE STRESS; TRANSGENES;

MUS MUSCULUS;

EID: 33749385911     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M605143200     Document Type: Article

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