The 15-Deoxy-Δ12,14-prostaglandin J2 inhibits LPS-stimulated AKT and NF-κB activation and suppresses interleukin-6 in osteoblast-like cells MC3T3E-1

Life Sciences

Volumn 85, Issue 1-2, 2009, Pages 46-53

  Jung, Won Kyo ^a   Park, Ik Su ^b   Park, Sang Jun ^b   Yea, Sung Su ^c   Choi, Yung Hyun ^d   Oh, Sangtaek ^e   Park, Sae Gwang ^c   Choi, Il Whan ^c  

^a Chosun University   (South Korea)

^b Inje University College of Medicine   (South Korea)

^c Inje University College of Medicine   (South Korea)

^d Dong Eui University   (South Korea)

^e Inje University   (South Korea)

Author keywords

15 deoxy 12,14 prostaglandin J2; Akt; Interleukin 6; Osteoblast like cells MC3T3E 1; Periodontitis

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; 2 CHLORO 5 NITROBENZANILIDE; DNA; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN KINASE B; TRANSCRIPTION FACTOR RELA; 15 DEOXYPROSTAGLANDIN J2; 15-DEOXYPROSTAGLANDIN J2; DRUG DERIVATIVE; ONCOPROTEIN; PROSTAGLANDIN D2;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONFOCAL LASER MICROSCOPY; CYTOKINE PRODUCTION; CYTOTOXICITY; DNA BINDING; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GEL MOBILITY SHIFT ASSAY; MOUSE; NONHUMAN; OSTEOBLAST; PERIODONTITIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CELL STRAIN 3T3; CELL SURVIVAL; CONFOCAL MICROSCOPY; DRUG ANTAGONISM; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE TRANSLOCATION; METABOLISM; PHYSIOLOGY;

3T3 CELLS; ANIMALS; BLOTTING, WESTERN; CELL SURVIVAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; I-KAPPA B PROTEINS; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MICE; MICROSCOPY, CONFOCAL; NF-KAPPA B; ONCOGENE PROTEIN V-AKT; OSTEOBLASTS; PPAR GAMMA; PROSTAGLANDIN D2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSLOCATION, GENETIC;

EID: 67349170406     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2009.04.010     Document Type: Article

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