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Volumn 182, Issue 9, 2009, Pages 5374-5381

ATLa, an aspirin-triggered lipoxin A4 synthetic analog, prevents the inflammatory and fibrotic effects of bleomycin-induced pulmonary fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA ACTIN; ASPIRIN TRIGGERED LIPOXIN A 4; BLEOMYCIN; ICOSANOID; LIPOXIN A; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; 16 (4 FLUOROPHENOXY)LIPOXIN A4; 16-(4-FLUOROPHENOXY)LIPOXIN A4; ANTIFIBRINOLYTIC AGENT; LIPOXIN; NONSTEROID ANTIINFLAMMATORY AGENT;

EID: 66949129763     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0802259     Document Type: Article
Times cited : (75)

References (68)
  • 2
    • 0019438740 scopus 로고
    • The myofibroblast: A key cell for wound healing and fibrocontractive diseases
    • Gabbiani, G. 1981. The myofibroblast: a key cell for wound healing and fibrocontractive diseases. Prog. Clin. Biol. Res. 54: 183-194.
    • (1981) Prog. Clin. Biol. Res. , vol.54 , pp. 183-194
    • Gabbiani, G.1
  • 3
    • 0020052468 scopus 로고
    • Structure of alveolar epithelial cells in patients with fibrotic lung disorders
    • Kawanami, O., V. J. Ferrans, and R. G. Crystal. 1982. Structure of alveolar epithelial cells in patients with fibrotic lung disorders. Lab Invest. 46: 39-53. (Pubitemid 12167015)
    • (1982) Laboratory Investigation , vol.46 , Issue.1 , pp. 39-53
    • Kawanami, O.1    Ferrans, V.J.2    Crystal, R.G.3
  • 4
    • 0027712613 scopus 로고
    • The pathogenesis of pulmonary fibrosis
    • Kuhn, C. 1993. The pathogenesis of pulmonary fibrosis. Monogr. Pathol. 78-92.
    • (1993) Monogr. Pathol. , pp. 78-92
    • Kuhn, C.1
  • 6
  • 7
    • 33749329160 scopus 로고    scopus 로고
    • Clinical review: Idiopathic pulmonary fibrosis-past, present and future
    • Dempsey, O. J. 2006. Clinical review: idiopathic pulmonary fibrosis-past, present and future. Respir. Med. 100: 1871-1885.
    • (2006) Respir. Med. , vol.100 , pp. 1871-1885
    • Dempsey, O.J.1
  • 9
    • 0034827655 scopus 로고    scopus 로고
    • Bleomycin-induced pneumonitis
    • Sleijfer, S. 2001. Bleomycin-induced pneumonitis. Chest 120: 617-624.
    • (2001) Chest , vol.120 , pp. 617-624
    • Sleijfer, S.1
  • 10
    • 0021288063 scopus 로고
    • Drug-induced pulmonary fibrosis
    • Adamson, I. Y. 1984. Drug-induced pulmonary fibrosis. Environ. Health Perspect. 55: 25-36.
    • (1984) Environ. Health Perspect. , vol.55 , pp. 25-36
    • Adamson, I.Y.1
  • 11
    • 1542362543 scopus 로고    scopus 로고
    • Mechanisms in pulmonary toxicology
    • Delaunois, L. M. 2004. Mechanisms in pulmonary toxicology. Clin. Chest Med. 25: 1-14.
    • (2004) Clin. Chest Med. , vol.25 , pp. 1-14
    • Delaunois, L.M.1
  • 12
    • 0026059699 scopus 로고
    • Mechanisms of bleomycin-induced lung damage
    • Hay, J., S. Shahzeidi, and G. Laurent. 1991. Mechanisms of bleomycin-induced lung damage. Arch. Toxicol. 65: 81-94.
    • (1991) Arch. Toxicol. , vol.65 , pp. 81-94
    • Hay, J.1    Shahzeidi, S.2    Laurent, G.3
  • 13
    • 34547731349 scopus 로고    scopus 로고
    • The effect of treatment of cystic fibrosis pulmonary exacerbations on airways and systemic inflammation
    • Downey, D. G., S. Brockbank, S. L. Martin, M. Ennis, and J. S. Elborn. 2007. The effect of treatment of cystic fibrosis pulmonary exacerbations on airways and systemic inflammation. Pediatr. Pulmonol. 42: 729-735.
    • (2007) Pediatr. Pulmonol. , vol.42 , pp. 729-735
    • Downey, D.G.1    Brockbank, S.2    Martin, S.L.3    Ennis, M.4    Elborn, J.S.5
  • 14
    • 33745453175 scopus 로고    scopus 로고
    • Treatment of idiopathic pulmonary fibrosis
    • Dury, S. 2006. Treatment of idiopathic pulmonary fibrosis. Rev. Mal. Respir. 23: 5S87-5S91.
    • (2006) Rev. Mal. Respir. , vol.23
    • Dury, S.1
  • 15
    • 0029995678 scopus 로고    scopus 로고
    • Corticosteroids and the treatment of idiopathic pulmonary fibrosis. Past, present, and future
    • Mapel, D. W., J. M. Samet, and D. B. Coultas. 1996. Corticosteroids and the treatment of idiopathic pulmonary fibrosis. Past, present, and future. Chest 110: 1058-1067.
    • (1996) Chest , vol.110 , pp. 1058-1067
    • Mapel, D.W.1    Samet, J.M.2    Coultas, D.B.3
  • 16
    • 26844506715 scopus 로고    scopus 로고
    • Current and future therapeutic approaches in idiopathic pulmonary fibrosis
    • DOI 10.1183/09031936.05.00145004
    • Bouros, D., and K. M. Antoniou. 2005. Current and future therapeutic approaches in idiopathic pulmonary fibrosis. Eur. Respir. J. 26: 693-702. (Pubitemid 41448670)
    • (2005) European Respiratory Journal , vol.26 , Issue.4 , pp. 693-702
    • Bouros, D.1    Antoniou, K.M.2
  • 17
  • 18
    • 0035524474 scopus 로고    scopus 로고
    • Molecular mechanisms of pulmonary fibrosis and current treatment
    • Kuwano, K., N. Hagimoto, and N. Hara. 2001. Molecular mechanisms of pulmonary fibrosis and current treatment. Curr. Mol. Med. 1: 551-573. (Pubitemid 33772035)
    • (2001) Current Molecular Medicine , vol.1 , Issue.5 , pp. 551-573
    • Kuwano, K.1    Hagimoto, N.2    Hara, N.3
  • 19
    • 0035348171 scopus 로고    scopus 로고
    • Mechanisms in anti-inflammation and resolution: The role of lipoxins and aspirin-triggered lipoxins
    • Fierro, I. M., and C. N. Serhan. 2001. Mechanisms in anti-inflammation and resolution: the role of lipoxins and aspirin-triggered lipoxins. Braz. J. Med. Biol. Res. 34: 555-566.
    • (2001) Braz. J. Med. Biol. Res. , vol.34 , pp. 555-566
    • Fierro, I.M.1    Serhan, C.N.2
  • 20
    • 24344469200 scopus 로고    scopus 로고
    • Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution
    • Serhan, C. N. 2005. Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution. Prostaglandins Leukot. Essent. Fatty Acids 73: 141-162.
    • (2005) Prostaglandins Leukot. Essent. Fatty Acids , vol.73 , pp. 141-162
    • Serhan, C.N.1
  • 21
    • 0028818271 scopus 로고
    • Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions
    • Claria, J., and C. N. Serhan. 1995. Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions. Proc. Natl. Acad. Sci. USA 92: 9475-9479.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9475-9479
    • Claria, J.1    Serhan, C.N.2
  • 23
    • 0942301316 scopus 로고    scopus 로고
    • Lipoxins: Endogenous regulators of inflammation
    • McMahon, B., and C. Godson. 2004. Lipoxins: endogenous regulators of inflammation. Am. J. Physiol. 286: F189-F201.
    • (2004) Am. J. Physiol. , vol.286
    • McMahon, B.1    Godson, C.2
  • 26
    • 18544378668 scopus 로고    scopus 로고
    • Lipoxins, aspirintriggered epi-lipoxins, lipoxin stable analogues, and the resolution of inflammation: Stimulation of macrophage phagocytosis of apoptotic neutrophils in vivo
    • Mitchell, S., G. Thomas, K. Harvey, D. Cottell, K. Reville, G. Berlasconi, N. A. Petasis, L. Erwig, A. J. Rees, J. Savill, et al. 2002. Lipoxins, aspirintriggered epi-lipoxins, lipoxin stable analogues, and the resolution of inflammation: stimulation of macrophage phagocytosis of apoptotic neutrophils in vivo. J. Am. Soc. Nephrol. 13: 2497-2507.
    • (2002) J. Am. Soc. Nephrol. , vol.13 , pp. 2497-2507
    • Mitchell, S.1    Thomas, G.2    Harvey, K.3    Cottell, D.4    Reville, K.5    Berlasconi, G.6    Petasis, N.A.7    Erwig, L.8    Rees, A.J.9    Savill, J.10
  • 27
    • 0033529195 scopus 로고    scopus 로고
    • Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo
    • Clish, C. B., J. A. O'Brien, K. Gronert, G. L. Stahl, N. A. Petasis, and C. N. Serhan. 1999. Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo. Proc. Natl. Acad. Sci. USA 96: 8247-8252.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 8247-8252
    • Clish, C.B.1    O'Brien, J.A.2    Gronert, K.3    Stahl, G.L.4    Petasis, N.A.5    Serhan, C.N.6
  • 28
    • 0038037241 scopus 로고    scopus 로고
    • Exploring new approaches to the treatment of asthma: Potential roles for lipoxins and aspirin-triggered lipid mediators
    • Levy, B. D., and C. N. Serhan. 2003. Exploring new approaches to the treatment of asthma: potential roles for lipoxins and aspirin-triggered lipid mediators. Drugs Today 39: 373-384.
    • (2003) Drugs Today , vol.39 , pp. 373-384
    • Levy, B.D.1    Serhan, C.N.2
  • 31
    • 33746885142 scopus 로고    scopus 로고
    • Myofibroblast transdifferentiation in obliterative bronchiolitis: TGF-β signaling through Smad3-dependent and -independent pathways
    • Ramirez, A. M., Z. Shen, J. D. Ritzenthaler, and J. Roman. 2006. Myofibroblast transdifferentiation in obliterative bronchiolitis: TGF-β signaling through Smad3-dependent and -independent pathways. Am. J. Transplant. 6: 2080-2088.
    • (2006) Am. J. Transplant. , vol.6 , pp. 2080-2088
    • Ramirez, A.M.1    Shen, Z.2    Ritzenthaler, J.D.3    Roman, J.4
  • 32
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 34
    • 43449131255 scopus 로고    scopus 로고
    • A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis
    • DOI 10.2353/ajpath.2008.070832
    • Trujillo, G., E. C. O'Connor, S. L. Kunkel, and C. M. Hogaboam. 2008. A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis. Am. J. Pathol. 172: 1209-1221. (Pubitemid 351671535)
    • (2008) American Journal of Pathology , vol.172 , Issue.5 , pp. 1209-1221
    • Trujillo, G.1    O'Connor, E.C.2    Kunkel, S.L.3    Hogaboam, C.M.4
  • 35
    • 33745996622 scopus 로고
    • The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid
    • Woessner, J. F., Jr. 1961. The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Arch. Biochem. Biophys. 93: 440-447.
    • (1961) Arch. Biochem. Biophys. , vol.93 , pp. 440-447
    • Woessner Jr., J.F.1
  • 37
    • 33744938426 scopus 로고    scopus 로고
    • Matrix metalloproteases in aberrant fibrotic tissue remodeling
    • DOI 10.1513/pats.200601-012TK
    • Pardo, A., and M. Selman. 2006. Matrix metalloproteases in aberrant fibrotic tissue remodeling. Proc. Am. Thorac. Soc. 3: 383-388. (Pubitemid 43845417)
    • (2006) Proceedings of the American Thoracic Society , vol.3 , Issue.4 , pp. 383-388
    • Pardo, A.1    Selman, M.2
  • 38
    • 35448988114 scopus 로고    scopus 로고
    • Molecular targets in pulmonary fibrosis: The myofibroblast in focus
    • DOI 10.1378/chest.06-2568
    • Scotton, C. J., and R. C. Chambers. 2007. Molecular targets in pulmonary fibrosis: the myofibroblast in focus. Chest 132: 1311-1321. (Pubitemid 47621009)
    • (2007) Chest , vol.132 , Issue.4 , pp. 1311-1321
    • Scotton, C.J.1    Chambers, R.C.2
  • 39
    • 33847350691 scopus 로고    scopus 로고
    • Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
    • Wynn, T. A. 2007. Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. J. Clin. Invest. 117: 524-529.
    • (2007) J. Clin. Invest. , vol.117 , pp. 524-529
    • Wynn, T.A.1
  • 40
    • 38549159026 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of fibrosis
    • Wynn, T. A. 2008. Cellular and molecular mechanisms of fibrosis. J. Pathol. 214: 199-210.
    • (2008) J. Pathol. , vol.214 , pp. 199-210
    • Wynn, T.A.1
  • 41
    • 33847361903 scopus 로고    scopus 로고
    • Infectious disease, the innate immune response, and fibrosis
    • DOI 10.1172/JCI30595
    • Meneghin, A., and C. M. Hogaboam. 2007. Infectious disease, the innate immune response, and fibrosis. J. Clin. Invest. 117: 530-538. (Pubitemid 46348507)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.3 , pp. 530-538
    • Meneghin, A.1    Hogaboam, C.M.2
  • 42
    • 4243944861 scopus 로고    scopus 로고
    • Molecular mechanisms of pulmonary fibrosis
    • Pardo, A., and M. Selman. 2002. Molecular mechanisms of pulmonary fibrosis. Front. Biosci. 7: 1743-1761.
    • (2002) Front. Biosci. , vol.7 , pp. 1743-1761
    • Pardo, A.1    Selman, M.2
  • 43
    • 34147097536 scopus 로고    scopus 로고
    • Cysteinyl-leukotriene 1 receptor antagonist attenuates bleomycin-induced pulmonary fibrosis in mice
    • DOI 10.1016/j.lfs.2007.02.038, PII S0024320507002081
    • Izumo, T., M. Kondo, and A. Nagai. 2007. Cysteinyl-leukotriene 1 receptor antagonist attenuates bleomycin-induced pulmonary fibrosis in mice. Life Sci. 80: 1882-1886. (Pubitemid 46560739)
    • (2007) Life Sciences , vol.80 , Issue.20 , pp. 1882-1886
    • Izumo, T.1    Kondo, M.2    Nagai, A.3
  • 44
    • 34250010862 scopus 로고    scopus 로고
    • Synthesis and anti-inflammatory effect of lipoxins in human airway epithelial cells
    • DOI 10.1016/j.biopha.2007.02.016, PII S0753332207000339
    • Bonnans, C., D. Gras, C. Chavis, B. Mainprice, I. Vachier, P. Godard, and P. Chanez. 2007. Synthesis and anti-inflammatory effect of lipoxins in human airway epithelial cells. Biomed. Pharmacother. 61: 261-267. (Pubitemid 46891725)
    • (2007) Biomedicine and Pharmacotherapy , vol.61 , Issue.5 , pp. 261-267
    • Bonnans, C.1    Gras, D.2    Chavis, C.3    Mainprice, B.4    Vachier, I.5    Godard, P.6    Chanez, P.7
  • 46
    • 0025001876 scopus 로고
    • Lipoxin formation in human nasal polyps and bronchial tissue
    • DOI 10.1016/0014-5793(90)80440-T
    • Edenius, C., M. Kumlin, T. Bjork, A. Anggard, and J. A. Lindgren. 1990. Lipoxin formation in human nasal polyps and bronchial tissue. FEBS Lett. 272: 25-28. (Pubitemid 20348973)
    • (1990) FEBS Letters , vol.272 , Issue.1-2 , pp. 25-28
    • Edenius, C.1    Kumlin, M.2    Bjork, T.3    Anggard, A.4    Lindgren, J.A.5
  • 48
    • 0027283573 scopus 로고
    • Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins
    • Levy, B. D., M. Romano, H. A. Chapman, J. J. Reilly, J. Drazen, and C. N. Serhan. 1993. Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins. J. Clin. Invest. 92: 1572-1579.
    • (1993) J. Clin. Invest. , vol.92 , pp. 1572-1579
    • Levy, B.D.1    Romano, M.2    Chapman, H.A.3    Reilly, J.J.4    Drazen, J.5    Serhan, C.N.6
  • 49
    • 33744480779 scopus 로고    scopus 로고
    • Lipoxin and synthetic lipoxin analogs: An overview of anti-inflammatory functions and new concepts in immunomodulation
    • Parkinson, J. F. 2006. Lipoxin and synthetic lipoxin analogs: an overview of anti-inflammatory functions and new concepts in immunomodulation. Inflamm. Allergy Drug Targets 5: 91-106.
    • (2006) Inflamm. Allergy Drug Targets , vol.5 , pp. 91-106
    • Parkinson, J.F.1
  • 52
    • 17044377563 scopus 로고    scopus 로고
    • Cyclooxygenase 2 plays a pivotal role in the resolution of acute lung injury
    • Fukunaga, K., P. Kohli, C. Bonnans, L. E. Fredenburgh, and B. D. Levy. 2005. Cyclooxygenase 2 plays a pivotal role in the resolution of acute lung injury. J. Immunol. 174: 5033-5039. (Pubitemid 40504588)
    • (2005) Journal of Immunology , vol.174 , Issue.8 , pp. 5033-5039
    • Fukunaga, K.1    Kohli, P.2    Bonnans, C.3    Fredenburgh, L.E.4    Levy, B.D.5
  • 55
    • 24044486529 scopus 로고    scopus 로고
    • 4 modifies platelet-derived growth factor-induced pro-fibrotic gene expression in human renal mesangial cells
    • 4 modifies platelet-derived growth factor-induced pro-fibrotic gene expression in human renal mesangial cells. Am. J. Pathol. 167: 683-694.
    • (2005) Am. J. Pathol. , vol.167 , pp. 683-694
    • Rodgers, K.1    McMahon, B.2    Mitchell, D.3    Sadlier, D.4    Godson, C.5
  • 56
    • 33644662853 scopus 로고    scopus 로고
    • 4 inhibits connective tissue growth factor-induced production of chemokines in rat mesangial cells
    • 4 inhibits connective tissue growth factor-induced production of chemokines in rat mesangial cells. Kidney Int. 69: 248-256.
    • (2006) Kidney Int. , vol.69 , pp. 248-256
    • Wu, S.H.1    Wu, X.H.2    Lu, C.3    Dong, L.4    Zhou, G.P.5    Chen, Z.Q.6
  • 57
    • 0036933489 scopus 로고    scopus 로고
    • The myofibroblast in pulmonary fibrosis
    • Phan, S. H. 2002. The myofibroblast in pulmonary fibrosis. Chest 122(Suppl. 6): 286S-289S.
    • (2002) Chest , vol.122 , Issue.SUPPL. 6
    • Phan, S.H.1
  • 58
    • 42049111233 scopus 로고    scopus 로고
    • Escape from the matrix: Multiple mechanisms for fibroblast activation in pulmonary fibrosis
    • Laurent, G. J., R. J. McAnulty, M. Hill, and R. Chambers. 2008. Escape from the matrix: multiple mechanisms for fibroblast activation in pulmonary fibrosis. Proc. Am. Thorac. Soc. 5: 311-315.
    • (2008) Proc. Am. Thorac. Soc. , vol.5 , pp. 311-315
    • Laurent, G.J.1    McAnulty, R.J.2    Hill, M.3    Chambers, R.4
  • 59
    • 42049109309 scopus 로고    scopus 로고
    • What differentiates normal lung repair and fibrosis? Inflammation, resolution of repair, and fibrosis
    • Strieter, R. M. 2008. What differentiates normal lung repair and fibrosis? Inflammation, resolution of repair, and fibrosis. Proc. Am. Thorac. Soc. 5: 305-310.
    • (2008) Proc. Am. Thorac. Soc. , vol.5 , pp. 305-310
    • Strieter, R.M.1
  • 62
    • 39149133154 scopus 로고    scopus 로고
    • Murine models of pulmonary fibrosis
    • Moore, B. B., and C. M. Hogaboam. 2008. Murine models of pulmonary fibrosis. Am. J. Physiol. 294: L152-L160.
    • (2008) Am. J. Physiol. , vol.294
    • Moore, B.B.1    Hogaboam, C.M.2
  • 66
    • 24944542889 scopus 로고    scopus 로고
    • 4 inhibits TNF-α-induced production of interleukins and proliferation of rat mesangial cells
    • 4 inhibits TNF-α-induced production of interleukins and proliferation of rat mesangial cells. Kidney Int. 68: 35-46.
    • (2005) Kidney Int. , vol.68 , pp. 35-46
    • Wu, S.H.1    Lu, C.2    Dong, L.3    Zhou, G.P.4    He, Z.G.5    Chen, Z.Q.6
  • 68
    • 0034144689 scopus 로고    scopus 로고
    • 4 inhibits IL-1β-induced IL-6, IL-8, and matrix metalloproteinase-3 production in human synovial fibroblasts and enhances synthesis of tissue inhibitors of metalloproteinases
    • 4 inhibits IL-1β-induced IL-6, IL-8, and matrix metalloproteinase-3 production in human synovial fibroblasts and enhances synthesis of tissue inhibitors of metalloproteinases. J. Immunol. 164: 2660-2666.
    • (2000) J. Immunol. , vol.164 , pp. 2660-2666
    • Sodin-Semrl, S.1    Taddeo, B.2    Tseng, D.3    Varga, J.4    Fiore, S.5


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