메뉴 건너뛰기




Volumn 5, Issue 3, 2008, Pages 311-315

Escape from the matrix: Multiple mechanisms for fibroblast activation in pulmonary fibrosis

Author keywords

Fibroblasts; Lung fibrosis; Matrix

Indexed keywords

ANGIOTENSIN; CYTOKINE; ENDOTHELIN; VASOCONSTRICTOR AGENT;

EID: 42049111233     PISSN: 15463222     EISSN: None     Source Type: Journal    
DOI: 10.1513/pats.200710-159DR     Document Type: Conference Paper
Times cited : (41)

References (71)
  • 2
    • 34447572685 scopus 로고    scopus 로고
    • Clinical relevance of airway remodelling in airway diseases
    • James AL, Wenzel S. Clinical relevance of airway remodelling in airway diseases. Eur Respir J 2007;30:134-155.
    • (2007) Eur Respir J , vol.30 , pp. 134-155
    • James, A.L.1    Wenzel, S.2
  • 5
    • 0023092732 scopus 로고
    • Dynamic state of collagen: Pathways of collagen degradation in vivo and their possible role in regulation of collagen mass
    • Laurent GJ. Dynamic state of collagen: pathways of collagen degradation in vivo and their possible role in regulation of collagen mass. Am J Physiol 1987;252:C1-C9.
    • (1987) Am J Physiol , vol.252
    • Laurent, G.J.1
  • 6
    • 13344278777 scopus 로고    scopus 로고
    • Matrix proteins
    • Gibson GJ, Geddes DM, Costabel U, Sterk PJ, Corrin B, editors, 3rd ed. Oxford UK, Saunders;
    • Dunsmore SE, Chambers RC, Laurent GJ. Matrix proteins. In: Gibson GJ, Geddes DM, Costabel U, Sterk PJ, Corrin B, editors. Respiratory medicine, 3rd ed. Oxford (UK): Saunders; 2003. pp. 82-92.
    • (2003) Respiratory medicine , pp. 82-92
    • Dunsmore, S.E.1    Chambers, R.C.2    Laurent, G.J.3
  • 7
    • 33847676783 scopus 로고    scopus 로고
    • Fibroblasts and myofibroblasts: Their source, function and role in disease
    • McAnulty RJ. Fibroblasts and myofibroblasts: their source, function and role in disease. Int J Biochem Cell Biol 2007;39:666-671.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 666-671
    • McAnulty, R.J.1
  • 8
    • 0026078964 scopus 로고
    • The effect of transforming growth factor β on rates of procollagen synthesis and degradation in vitro
    • McAnulty RJ, Campa JS, Cambrey AD, Laurent GJ. The effect of transforming growth factor β on rates of procollagen synthesis and degradation in vitro. Biochim Biophys Acta 1991;1091:231-235.
    • (1991) Biochim Biophys Acta , vol.1091 , pp. 231-235
    • McAnulty, R.J.1    Campa, J.S.2    Cambrey, A.D.3    Laurent, G.J.4
  • 9
    • 0037155278 scopus 로고    scopus 로고
    • Activation of fibroblast procollagen α 1(I) transcription by mechanical strain is transforming growth factor-β- dependent and involves increased binding of CCAAT-binding factor (CBF/NF-Y) at the proximal promoter
    • Lindahl GE, Chambers RC, Papakrivopoulou J, Dawson SJ, Jacobsen MC, Bishop JE, Laurent GJ. Activation of fibroblast procollagen α 1(I) transcription by mechanical strain is transforming growth factor-β- dependent and involves increased binding of CCAAT-binding factor (CBF/NF-Y) at the proximal promoter. J Biol Chem 2002;277:6153-6161.
    • (2002) J Biol Chem , vol.277 , pp. 6153-6161
    • Lindahl, G.E.1    Chambers, R.C.2    Papakrivopoulou, J.3    Dawson, S.J.4    Jacobsen, M.C.5    Bishop, J.E.6    Laurent, G.J.7
  • 10
    • 0037331234 scopus 로고    scopus 로고
    • Global expression profiling of fibroblast responses to transforming growth factor-β1 reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic switching
    • Chambers RC, Leoni P, Kaminski N, Laurent GJ, Heller RA. Global expression profiling of fibroblast responses to transforming growth factor-β1 reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic switching. Am J Pathol 2003;162:533-546.
    • (2003) Am J Pathol , vol.162 , pp. 533-546
    • Chambers, R.C.1    Leoni, P.2    Kaminski, N.3    Laurent, G.J.4    Heller, R.A.5
  • 13
    • 0030963536 scopus 로고    scopus 로고
    • Anti-cytokine approaches in pulmonary fibrosis: Bringing factors into focus
    • Coker RK, Laurent GJ. Anti-cytokine approaches in pulmonary fibrosis: bringing factors into focus. Thorax 1997;52:294-296.
    • (1997) Thorax , vol.52 , pp. 294-296
    • Coker, R.K.1    Laurent, G.J.2
  • 14
    • 0031833250 scopus 로고    scopus 로고
    • Pulmonary fibrosis: Cytokines in the balance
    • Coker RK, Laurent GJ. Pulmonary fibrosis: cytokines in the balance. Eur Respir J 1998;11:1218-1221.
    • (1998) Eur Respir J , vol.11 , pp. 1218-1221
    • Coker, R.K.1    Laurent, G.J.2
  • 15
    • 33646746153 scopus 로고    scopus 로고
    • TGF-β: Its role in asthma and therapeutic potential
    • Howell JE, McAnulty RJ. TGF-β: its role in asthma and therapeutic potential. Curr Drug Targets 2006;7:547-565.
    • (2006) Curr Drug Targets , vol.7 , pp. 547-565
    • Howell, J.E.1    McAnulty, R.J.2
  • 16
    • 0031059572 scopus 로고    scopus 로고
    • Transforming growth factors-β1, -β2, and -β3 stimulate fibroblast procollagen production in vitro but are differentially expressed during bleomycin-induced lung fibrosis
    • Coker RK, Laurent GJ, Shahzeidi S, Lympany PA, du Bois RM, Jeffery PK, McAnulty RJ. Transforming growth factors-β1, -β2, and -β3 stimulate fibroblast procollagen production in vitro but are differentially expressed during bleomycin-induced lung fibrosis. Am J Pathol 1997;150:981-991.
    • (1997) Am J Pathol , vol.150 , pp. 981-991
    • Coker, R.K.1    Laurent, G.J.2    Shahzeidi, S.3    Lympany, P.A.4    du Bois, R.M.5    Jeffery, P.K.6    McAnulty, R.J.7
  • 19
    • 0002604460 scopus 로고
    • Pathogenesis of pulmonary fibrosis: Implications for pharmacological intervention
    • Walters EH, du Bois RM, editors, London: Chapman & Hall;
    • Coker RK, Laurent GJ. Pathogenesis of pulmonary fibrosis: implications for pharmacological intervention. In: Walters EH, du Bois RM, editors. Immunology and interstitial lung disease. London: Chapman & Hall; 1995. pp. 19-36.
    • (1995) Immunology and interstitial lung disease , pp. 19-36
    • Coker, R.K.1    Laurent, G.J.2
  • 20
    • 0034047028 scopus 로고    scopus 로고
    • Angiotensin II is mitogenic for human lung fibroblasts via activation of the type 1 receptor
    • Marshall RP, McAnulty RJ, Laurent GJ. Angiotensin II is mitogenic for human lung fibroblasts via activation of the type 1 receptor. Am J Respir Crit Care Med 2000;161:1999-2004.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 1999-2004
    • Marshall, R.P.1    McAnulty, R.J.2    Laurent, G.J.3
  • 23
    • 0031721725 scopus 로고    scopus 로고
    • The acute respiratory distress syndrome: Fibrosis in the fast lane
    • Marshall R, Bellingan GJ, Laurent GJ. The acute respiratory distress syndrome: fibrosis in the fast lane. Thorax 1998;53:815-817.
    • (1998) Thorax , vol.53 , pp. 815-817
    • Marshall, R.1    Bellingan, G.J.2    Laurent, G.J.3
  • 24
    • 0033592753 scopus 로고    scopus 로고
    • A preliminary study of long-term treatment with interferon gamma-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis
    • Ziesche R, Hofbauer E, Wittmann K, Petkov V, Block LH. A preliminary study of long-term treatment with interferon gamma-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis. N Engl J Med 1999;341:1264-1269.
    • (1999) N Engl J Med , vol.341 , pp. 1264-1269
    • Ziesche, R.1    Hofbauer, E.2    Wittmann, K.3    Petkov, V.4    Block, L.H.5
  • 26
    • 0028913974 scopus 로고
    • Regulation of fibroblast procollagen production: Transforming growth factor-β1 induces prostaglandin E2 but not procollagen synthesis via a pertussis toxin-sensitive G-protein
    • McAnulty RJ, Chambers RC, Laurent GJ. Regulation of fibroblast procollagen production: transforming growth factor-β1 induces prostaglandin E2 but not procollagen synthesis via a pertussis toxin-sensitive G-protein. Biochem J 1995;307:63-68.
    • (1995) Biochem J , vol.307 , pp. 63-68
    • McAnulty, R.J.1    Chambers, R.C.2    Laurent, G.J.3
  • 27
    • 0031045301 scopus 로고    scopus 로고
    • Indomethacin suppresses the anti-proliferative effects of transforming growth factor-β isoforms on fibroblast cell cultures
    • McAnulty RJ, Hernandez-Rodriguez NA, Mutsaers SE, Coker RK, Laurent GJ. Indomethacin suppresses the anti-proliferative effects of transforming growth factor-β isoforms on fibroblast cell cultures. Biochem J 1997;321:639-643.
    • (1997) Biochem J , vol.321 , pp. 639-643
    • McAnulty, R.J.1    Hernandez-Rodriguez, N.A.2    Mutsaers, S.E.3    Coker, R.K.4    Laurent, G.J.5
  • 28
    • 0028924146 scopus 로고
    • Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2
    • Wilborn J, Crofford LJ, Burdick MD, Kunkel SL, Strieter RM, Peters-Golden M. Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2. J Clin Invest 1995;4:1861-1868.
    • (1995) J Clin Invest , vol.4 , pp. 1861-1868
    • Wilborn, J.1    Crofford, L.J.2    Burdick, M.D.3    Kunkel, S.L.4    Strieter, R.M.5    Peters-Golden, M.6
  • 29
    • 0035070056 scopus 로고    scopus 로고
    • Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-β in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice
    • Keerthisingam CB, Jenkins RG, Harrison NK, Hernandez-Rodriquez NA, Booth H, Laurent GJ, Hart SL, Foster ML, McAnulty RJ. Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-β in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice. Am J Pathol 2001;58:1411-1422.
    • (2001) Am J Pathol , vol.58 , pp. 1411-1422
    • Keerthisingam, C.B.1    Jenkins, R.G.2    Harrison, N.K.3    Hernandez-Rodriquez, N.A.4    Booth, H.5    Laurent, G.J.6    Hart, S.L.7    Foster, M.L.8    McAnulty, R.J.9
  • 36
    • 0030029719 scopus 로고    scopus 로고
    • Administration of truncated secretory leukoprotease inhibitor ameliorates bleomycin-induced pulmonary fibrosis in hamsters
    • Mitsuhashi H, Asano S, Nonaka T, Hamamura I, Masuda K-I, Kiyoki M. Administration of truncated secretory leukoprotease inhibitor ameliorates bleomycin-induced pulmonary fibrosis in hamsters. Am J Respir Crit Care Med 1996;153:369-374.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 369-374
    • Mitsuhashi, H.1    Asano, S.2    Nonaka, T.3    Hamamura, I.4    Masuda, K.-I.5    Kiyoki, M.6
  • 37
    • 0030741005 scopus 로고    scopus 로고
    • Effects of neutrophil elastase inhibitor on bleomycin-induced pulmonary fibrosis in mice
    • Taooka Y, Maeda A, Hiyama K, Ishioka S, Yamakido M. Effects of neutrophil elastase inhibitor on bleomycin-induced pulmonary fibrosis in mice. Am J Respir Crit Care Med 1997;156:260-265.
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 260-265
    • Taooka, Y.1    Maeda, A.2    Hiyama, K.3    Ishioka, S.4    Yamakido, M.5
  • 39
    • 0032126368 scopus 로고    scopus 로고
    • Thrombin stimulates fibroblast procollagen production via proteolytic activation of protease-activated receptor 1
    • Chambers RC, Dabbagh K, McAnulty RJ, Gray AJ, Blanc-Brude O, Laurent GJ. Thrombin stimulates fibroblast procollagen production via proteolytic activation of protease-activated receptor 1. Biochem J 1998;333:121-127.
    • (1998) Biochem J , vol.333 , pp. 121-127
    • Chambers, R.C.1    Dabbagh, K.2    McAnulty, R.J.3    Gray, A.J.4    Blanc-Brude, O.5    Laurent, G.J.6
  • 40
    • 0034634622 scopus 로고    scopus 로고
    • Thrombin is a potent inducer of connective tissue growth factor production via proteolytic activation of protease-activated receptor-1
    • Chambers RC, Leoni P, Blanc-Brude OP, Wembridge DE, Laurent GJ. Thrombin is a potent inducer of connective tissue growth factor production via proteolytic activation of protease-activated receptor-1. J Biol Chem 2000;275:35584-35591.
    • (2000) J Biol Chem , vol.275 , pp. 35584-35591
    • Chambers, R.C.1    Leoni, P.2    Blanc-Brude, O.P.3    Wembridge, D.E.4    Laurent, G.J.5
  • 41
    • 0031815996 scopus 로고    scopus 로고
    • From clot to collagen: Coagulation peptides in interstitial lung disease
    • Dabbagh K, Chambers RC, Laurent GJ. From clot to collagen: coagulation peptides in interstitial lung disease. Eur Respir J 1998;11:1002-1005.
    • (1998) Eur Respir J , vol.11 , pp. 1002-1005
    • Dabbagh, K.1    Chambers, R.C.2    Laurent, G.J.3
  • 42
    • 0037386434 scopus 로고    scopus 로고
    • Science review: Role of coagulation protease cascades in sepsis
    • Ruf W, Riewald M. Science review: role of coagulation protease cascades in sepsis. Crit Care 2003;7:123-129.
    • (2003) Crit Care , vol.7 , pp. 123-129
    • Ruf, W.1    Riewald, M.2
  • 44
    • 0034795622 scopus 로고    scopus 로고
    • Direct thrombin inhibition reduces lung collagen, accumulation, and connective tissue growth factor mRNA levels in bleomycin-induced pulmonary fibrosis
    • Howell DCJ, Goldsack NR, Marshall RP, Starke R, Purdy G, Laurent GJ, Chambers RC. Direct thrombin inhibition reduces lung collagen, accumulation, and connective tissue growth factor mRNA levels in bleomycin-induced pulmonary fibrosis. Am J Pathol 2001;159:1383-1395.
    • (2001) Am J Pathol , vol.159 , pp. 1383-1395
    • Howell, D.C.J.1    Goldsack, N.R.2    Marshall, R.P.3    Starke, R.4    Purdy, G.5    Laurent, G.J.6    Chambers, R.C.7
  • 45
    • 17844399243 scopus 로고    scopus 로고
    • Absence of proteinase-activated receptor-1 signaling affords protection from bleomycin-induced lung inflammation and fibrosis
    • Howell DC, Johns RH, Lasky JA, Shan B, Scotton CJ, Laurent GJ, Chambers RC. Absence of proteinase-activated receptor-1 signaling affords protection from bleomycin-induced lung inflammation and fibrosis. Am J Pathol 2005;166:1353-1365.
    • (2005) Am J Pathol , vol.166 , pp. 1353-1365
    • Howell, D.C.1    Johns, R.H.2    Lasky, J.A.3    Shan, B.4    Scotton, C.J.5    Laurent, G.J.6    Chambers, R.C.7
  • 47
    • 0018907089 scopus 로고
    • Protein turnover during skeletal muscle hypertrophy
    • Laurent GJ, Millward DJ. Protein turnover during skeletal muscle hypertrophy. Fed Proc 1980;39:42-47.
    • (1980) Fed Proc , vol.39 , pp. 42-47
    • Laurent, G.J.1    Millward, D.J.2
  • 48
    • 4444367012 scopus 로고    scopus 로고
    • Regulation of connective tissue homeostasis in the skin by mechanical forces
    • Eckes B, Krieg T. Regulation of connective tissue homeostasis in the skin by mechanical forces. Clin Exp Rheumatol 2004;22(3, Suppl 33):S73-S76.
    • (2004) Clin Exp Rheumatol , vol.22 , Issue.3 and SUPPL. 33
    • Eckes, B.1    Krieg, T.2
  • 49
    • 0027770972 scopus 로고
    • The role of mechanical force in the regulation of fibroblast function: Implications for enhanced collagen deposition during pulmonary vascular remodelling
    • Bishop JE, Butt RP, Laurent GJ. The role of mechanical force in the regulation of fibroblast function: implications for enhanced collagen deposition during pulmonary vascular remodelling. European Respiratory Review 1993;3:613-617.
    • (1993) European Respiratory Review , vol.3 , pp. 613-617
    • Bishop, J.E.1    Butt, R.P.2    Laurent, G.J.3
  • 50
    • 33645973265 scopus 로고    scopus 로고
    • Chronic effects of mechanical force on airways
    • Tschumperlin DJ, Drazen JM. Chronic effects of mechanical force on airways. Annu Rev Physiol 2006;68:563-583.
    • (2006) Annu Rev Physiol , vol.68 , pp. 563-583
    • Tschumperlin, D.J.1    Drazen, J.M.2
  • 51
    • 0141723430 scopus 로고    scopus 로고
    • Mechanotransduction determines the structure and function of lung and bone: A theoretical model for the pathophysiology of chronic disease
    • Torday JS, Rehan VK. Mechanotransduction determines the structure and function of lung and bone: a theoretical model for the pathophysiology of chronic disease. Cell Biochem Biophys 2003;37:235-246.
    • (2003) Cell Biochem Biophys , vol.37 , pp. 235-246
    • Torday, J.S.1    Rehan, V.K.2
  • 52
    • 22744448697 scopus 로고    scopus 로고
    • Mechanical signals regulating extracellular matrix gene expression in fibroblasts
    • Sarasa-Renedo A, Chiquet M. Mechanical signals regulating extracellular matrix gene expression in fibroblasts. Scand J Med Sci Sports 2005;15:223-230.
    • (2005) Scand J Med Sci Sports , vol.15 , pp. 223-230
    • Sarasa-Renedo, A.1    Chiquet, M.2
  • 53
    • 7744232293 scopus 로고    scopus 로고
    • Activation of a signaling cascade by cytoskeleton stretch
    • Tamada M, Sheetz MP, Sawada Y. Activation of a signaling cascade by cytoskeleton stretch. Dev Cell 2004;7:709-718.
    • (2004) Dev Cell , vol.7 , pp. 709-718
    • Tamada, M.1    Sheetz, M.P.2    Sawada, Y.3
  • 54
    • 0041827247 scopus 로고    scopus 로고
    • Possible roles for apoptosis and apoptotic cell recognition in inflammation and fibrosis
    • Henson PM. Possible roles for apoptosis and apoptotic cell recognition in inflammation and fibrosis. Am J Respir Cell Mol Biol 2003;29(3, Suppl):S70-S76.
    • (2003) Am J Respir Cell Mol Biol , vol.29 , Issue.3 and SUPPL.
    • Henson, P.M.1
  • 56
    • 0032437815 scopus 로고    scopus 로고
    • Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung
    • Uhal BD, Joshi I, Hughes WF, Ramos C, Pardo A, Selman M. Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung. Am J Physiol 1998;275:L1192-L1199.
    • (1998) Am J Physiol , vol.275
    • Uhal, B.D.1    Joshi, I.2    Hughes, W.F.3    Ramos, C.4    Pardo, A.5    Selman, M.6
  • 57
    • 33744914050 scopus 로고    scopus 로고
    • Evolving concepts of apoptosis in idiopathic pulmonary fibrosis
    • Thannickal VJ, Horowitz JC. Evolving concepts of apoptosis in idiopathic pulmonary fibrosis. Proc Am Thorac Soc 2006;3:350-356.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 350-356
    • Thannickal, V.J.1    Horowitz, J.C.2
  • 59
    • 0033862955 scopus 로고    scopus 로고
    • Abrogation of bleomycin-induced epithelial apoptosis and lung fibrosis by captopril or by a caspase inhibitor
    • Wang R, Ibarra-Sunga O, Verlinski L, Pick R, Uhal BD. Abrogation of bleomycin-induced epithelial apoptosis and lung fibrosis by captopril or by a caspase inhibitor. Am J Physiol Lung Cell Mol Physiol 2000;279:L143-L151.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.279
    • Wang, R.1    Ibarra-Sunga, O.2    Verlinski, L.3    Pick, R.4    Uhal, B.D.5
  • 60
    • 33745860364 scopus 로고    scopus 로고
    • Transgenic modeling of transforming growth factor-β1: Role of apoptosis in fibrosis and alveolar remodeling
    • Lee CG, Kang HR, Homer RJ, Chupp G, Elias JA. Transgenic modeling of transforming growth factor-β1: role of apoptosis in fibrosis and alveolar remodeling. Proc Am Thorac Soc 2006;3:418-423.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 418-423
    • Lee, C.G.1    Kang, H.R.2    Homer, R.J.3    Chupp, G.4    Elias, J.A.5
  • 62
    • 25444432522 scopus 로고    scopus 로고
    • A new direction in the pathogenesis of idiopathic pulmonary fibrosis?
    • Gauldie J, Kolb M, Sime PJ. A new direction in the pathogenesis of idiopathic pulmonary fibrosis? Respir Res 2002;3:1.
    • (2002) Respir Res , vol.3 , pp. 1
    • Gauldie, J.1    Kolb, M.2    Sime, P.J.3
  • 63
    • 0035895243 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Prevailing and evolving hypotheses about its pathogenesis and implications for therapy
    • Selman M, King TE Jr, Pardo A. Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med 2001;134:136-151.
    • (2001) Ann Intern Med , vol.134 , pp. 136-151
    • Selman, M.1    King Jr, T.E.2    Pardo, A.3
  • 65
    • 0034785496 scopus 로고    scopus 로고
    • Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis
    • Yang J, Liu Y. Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am J Pathol 2001;159:1465-1475.
    • (2001) Am J Pathol , vol.159 , pp. 1465-1475
    • Yang, J.1    Liu, Y.2
  • 70
    • 38849178850 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Multiple causes and multiple mechanisms?
    • Maher TM, Wells AU, Laurent GJ. Idiopathic pulmonary fibrosis: multiple causes and multiple mechanisms? Eur Respir J 2007;30:835-839.
    • (2007) Eur Respir J , vol.30 , pp. 835-839
    • Maher, T.M.1    Wells, A.U.2    Laurent, G.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.