Increasing IgG concentration modulates the conformational heterogeneity and bonding network that influence solution properties

Journal of Physical Chemistry B

Volumn 113, Issue 17, 2009, Pages 6109-6118

  Kamerzell, Tim J ^a   Kanai, Sonoko ^a   Liu, Jun ^a   Shire, Steven J ^a   Wang, Y John ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDES; CONCENTRATION (PROCESS); HYDROGEN; HYDROGEN BONDS; MOLECULAR SPECTROSCOPY;

BONDING NETWORKS; CONCENTRATED SOLUTION; CONCENTRATION-DEPENDENT; CONFORMATIONAL HETEROGENEITY; DRIVING FORCES; HYDROGEN BONDINGS; INTENSITY VARIATIONS; INTERMOLECULAR ASSOCIATION; NON-IDEAL SOLUTION; NONIDEAL; PCA ANALYSIS; PRINCIPAL COMPONENTS ANALYSIS; PROTEIN STABILITY; SOLUTION PROPERTY; SPECIFIC SEQUENCES; VIBRATIONAL CORRELATION;

PRINCIPAL COMPONENT ANALYSIS;

EID: 66349132473     PISSN: 15206106     EISSN: None     Source Type: Journal    
DOI: 10.1021/jp9001548     Document Type: Article

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