Evolutionary constraints on structural similarity in orthologs and paralogs

Protein Science

Volumn 18, Issue 6, 2009, Pages 1306-1315

  Peterson, Mark E ^a,b   Chen, Feng ^c   Saven, Jeffery G ^c   Roos, David S ^c   Babbitt, Patricia C ^a,b   Sali, Andrej ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Homology modeling; Orthologs prediction; Orthology; Paralogy; Sequence structure relationship

Indexed keywords

AMINO ACID SEQUENCE; ARTICLE; EVOLUTION; LIGAND BINDING; MOLECULAR MODEL; ORTHOLOGY; PARALOGY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; STRUCTURAL GENOMICS;

AMINO ACID SEQUENCE; DATABASES, PROTEIN; EVOLUTION, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; PROTEINS; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 66349085886     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.143     Document Type: Article

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