Dynamic release of nuclear RanGTP triggers TPX2-dependent microtubule assembly during the apoptotic execution phase

Journal of Cell Science

Volumn 122, Issue 5, 2009, Pages 644-655

  Moss, David K ^a,c   Wilde, Andrew ^b   Lane, Jon D ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF TORONTO   (Canada)

^c NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Apoptosis; Microtubules; Ran; TPX2

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; BLEBBISTATIN; CELL PROTEIN; NUCLEAR PROTEIN; PROTEIN KID; PROTEIN MKLP1; RAN PROTEIN; SMALL INTERFERING RNA; TARGETING PROTEIN FOR XKLP2; UNCLASSIFIED DRUG; ACTIN; ANTINEOPLASTIC ANTIBIOTIC; CELL CYCLE PROTEIN; HYBRID PROTEIN; LEPTOMYCIN B; MICROTUBULE ASSOCIATED PROTEIN; MYOSIN II; TPX2 PROTEIN, HUMAN; UNSATURATED FATTY ACID;

ACTIN MYOSIN INTERACTION; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOPLASM; GENE SILENCING; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; INTERPHASE; MICROTUBULE ASSEMBLY; MITOSIS SPINDLE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; CELL NUCLEUS; GENETICS; METABOLISM; MICROTUBULE; PHYSIOLOGY;

ACTINS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; CELL CYCLE PROTEINS; CELL NUCLEUS; FATTY ACIDS, UNSATURATED; HELA CELLS; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MITOTIC SPINDLE APPARATUS; MYOSIN TYPE II; NUCLEAR PROTEINS; RAN GTP-BINDING PROTEIN; RECOMBINANT FUSION PROTEINS; RNA, SMALL INTERFERING;

EID: 66149115276     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.037259     Document Type: Article

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