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Volumn 53, Issue 4, 2009, Pages 479-491

Potential of deoxynivalenol to induce transcription factors in human hepatoma cells

Author keywords

Deoxynivalenol; Hep G2; MAPK; Mycotoxin; Transcription factors

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; ATF3 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE; MYCOTOXIN; TRANSCRIPTION FACTOR; TRICHOTHECENE DERIVATIVE; VOMITOXIN;

EID: 65749106346     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.200800475     Document Type: Article
Times cited : (27)

References (74)
  • 1
    • 65749097546 scopus 로고    scopus 로고
    • Fifty-Sixth Report of the Joint FAO/WHO Expert Committee on Food Additives. International Programme on Chemical Safety, World Health Organization, Geneva
    • Canady, R. A., Coker, R. D., Rgan, S. K., Krska, R., et al., Fifty-Sixth Report of the Joint FAO/WHO Expert Committee on Food Additives. International Programme on Chemical Safety, World Health Organization, Geneva 2001, pp. 420-555.
    • (2001) , pp. 420-555
    • Canady, R.A.1    Coker, R.D.2    Rgan, S.K.3    Krska, R.4
  • 3
    • 0034014127 scopus 로고    scopus 로고
    • Fusarium head blight pathogens isolated from fusarium-damaged kernels of wheat in western Canada, 1993 to 1998
    • Clear, R. M., Patrick, S. K., Fusarium head blight pathogens isolated from fusarium-damaged kernels of wheat in western Canada, 1993 to 1998, Can. J. Plant Pathol.-Revue Canadienne De Phytopathologie 2000, 22, 51-60.
    • (2000) Can. J. Plant Pathol.-Revue Canadienne De Phytopathologie , vol.22 , pp. 51-60
    • Clear, R.M.1    Patrick, S.K.2
  • 4
    • 38049084645 scopus 로고    scopus 로고
    • Occurrence of type A trichothecenes in conventionally and organically produced oats and oat products
    • Gottschalk, C., Barthel, J., Engelhardt, G., Bauer, J., Meyer, K., Occurrence of type A trichothecenes in conventionally and organically produced oats and oat products, Mol. Nutr. Food Res. 2007, 51, 1547-1553.
    • (2007) Mol. Nutr. Food Res. , vol.51 , pp. 1547-1553
    • Gottschalk, C.1    Barthel, J.2    Engelhardt, G.3    Bauer, J.4    Meyer, K.5
  • 5
    • 0037186863 scopus 로고    scopus 로고
    • Update of survey, regulation and toxic effects of mycotoxins in Europe
    • Creppy, E. E., Update of survey, regulation and toxic effects of mycotoxins in Europe, Toxicol. Lett. 2002, 127, 19-28.
    • (2002) Toxicol. Lett. , vol.127 , pp. 19-28
    • Creppy, E.E.1
  • 6
    • 0029299704 scopus 로고
    • Survey of deoxynivalenol in US 1993 wheat and barley corps by enzyme-linked-immunosorbent-assay
    • Trucksess, M.W., Thomas, F., Young, K., Stack, M. E., et al., Survey of deoxynivalenol in US 1993 wheat and barley corps by enzyme-linked-immunosorbent-assay, J. AOAC Int. 1995, 78, 631-636.
    • (1995) J. AOAC Int. , vol.78 , pp. 631-636
    • Trucksess, M.W.1    Thomas, F.2    Young, K.3    Stack, M.E.4
  • 7
    • 4444242108 scopus 로고    scopus 로고
    • Influence of processing on trichothecene levels
    • Hazel, C. M., Patel, S., Influence of processing on trichothecene levels, Toxicol. Lett. 2004, 153, 51-59.
    • (2004) Toxicol. Lett. , vol.153 , pp. 51-59
    • Hazel, C.M.1    Patel, S.2
  • 8
    • 0036234686 scopus 로고    scopus 로고
    • in: DeVries, J. W. (Ed.), Kluwer Academic/Plenum Publ., New York
    • Trigo-Stockli, D. M., in: DeVries, J. W. (Ed.), Mycotoxins and Food Safety, Kluwer Academic/Plenum Publ., New York 2002, pp. 181-188.
    • (2002) Mycotoxins and Food Safety , pp. 181-188
    • Trigo-Stockli, D.M.1
  • 10
    • 4444278963 scopus 로고    scopus 로고
    • Collection of Occurrence Data of fusarium toxins in Food and Assessment of Dietary Intake by the Population of EU Member States
    • SCOOP, SCOOP Task 3.2.10 Final Report
    • SCOOP, Collection of Occurrence Data of fusarium toxins in Food and Assessment of Dietary Intake by the Population of EU Member States, SCOOP Task 3.2.10 Final Report, 2003; http://europa.eu.int/comm/food/fs/scoop/task3210.pdf.
    • (2003)
  • 11
    • 40949132552 scopus 로고    scopus 로고
    • Urinary deoxynivalenol is correlated with cereal intake in individuals from the United Kingdom
    • Turner, P. C., Rothwell, J. A., White, K. L. M., Gong, Y., et al., Urinary deoxynivalenol is correlated with cereal intake in individuals from the United Kingdom, Environ. Health Perspect. 2008, 116, 21-25.
    • (2008) Environ. Health Perspect. , vol.116 , pp. 21-25
    • Turner, P.C.1    Rothwell, J.A.2    White, K.L.M.3    Gong, Y.4
  • 13
    • 2342658494 scopus 로고    scopus 로고
    • Effects of graded levels of Fusarium toxin contaminated wheat in diets for fattening pigs on growth performance, nutrient digestibility, deoxynivalenol balance and clinical serum characteristics
    • Danicke, S., Valenta, H., Klobasa, F., Doll, S., et al., Effects of graded levels of Fusarium toxin contaminated wheat in diets for fattening pigs on growth performance, nutrient digestibility, deoxynivalenol balance and clinical serum characteristics. Arch. Anim. Nutr.-Arch. Tierernahr. 2004, 58, 1-17.
    • (2004) Arch. Anim. Nutr.-Arch. Tierernahr. , vol.58 , pp. 1-17
    • Danicke, S.1    Valenta, H.2    Klobasa, F.3    Doll, S.4
  • 14
    • 33748354034 scopus 로고    scopus 로고
    • Subacute effects of moderate feed loads of isolated Fusarium toxin deoxynivalenol on selected parameters of metabolism in weaned growing piglets
    • Drochner, W., Schollenberger, M., Gotz, S., Lauber, U., et al., Subacute effects of moderate feed loads of isolated Fusarium toxin deoxynivalenol on selected parameters of metabolism in weaned growing piglets, J. Anim. Physiol. Anim. Nutr. 2006, 90, 421-428.
    • (2006) J. Anim. Physiol. Anim. Nutr. , vol.90 , pp. 421-428
    • Drochner, W.1    Schollenberger, M.2    Gotz, S.3    Lauber, U.4
  • 15
    • 49649099260 scopus 로고    scopus 로고
    • Residues of deoxynivalenol (DON) in pig tissue after feeding mash or pellet diets containing low concentrations
    • Doll, S., Danicke, S., Valenta, H., Residues of deoxynivalenol (DON) in pig tissue after feeding mash or pellet diets containing low concentrations, Mol. Nutr. Food Res. 2008, 52, 727-734.
    • (2008) Mol. Nutr. Food Res. , vol.52 , pp. 727-734
    • Doll, S.1    Danicke, S.2    Valenta, H.3
  • 16
    • 0037432624 scopus 로고    scopus 로고
    • Deoxynivalenol-induced IgA production and IgA nephropathy-aberrant mucosal immune response with systemic repercussions
    • Pestka, J. J., Deoxynivalenol-induced IgA production and IgA nephropathy-aberrant mucosal immune response with systemic repercussions, Toxicol. Lett. 2003, 140, 287-295.
    • (2003) Toxicol. Lett. , vol.140 , pp. 287-295
    • Pestka, J.J.1
  • 17
    • 10044261114 scopus 로고    scopus 로고
    • Induction of apoptosis and cytokine production in the Jurkat human T cells by deoxynivalenol: Role of mitogen-activated protein kinases and comparison to other 8-ketotrichothecenes
    • Pestka, J. J., Uzarski, R. L., Islam, Z., Induction of apoptosis and cytokine production in the Jurkat human T cells by deoxynivalenol: Role of mitogen-activated protein kinases and comparison to other 8-ketotrichothecenes, Toxicology 2005, 206, 207-219.
    • (2005) Toxicology , vol.206 , pp. 207-219
    • Pestka, J.J.1    Uzarski, R.L.2    Islam, Z.3
  • 18
    • 19444365938 scopus 로고    scopus 로고
    • Effects of trichothecene mycotoxins on eukaryotic cells: A review
    • Rocha, O., Ansari, K., Doohan, F. M., Effects of trichothecene mycotoxins on eukaryotic cells: A review. Food Addit. Contam. 2005, 22, 369-378.
    • (2005) Food Addit. Contam. , vol.22 , pp. 369-378
    • Rocha, O.1    Ansari, K.2    Doohan, F.M.3
  • 19
    • 38449102293 scopus 로고    scopus 로고
    • Transcriptional regulation of deoxynivalenol- induced IL-8 expression in human monocytes
    • Gray, J. S., Pestka, J. J., Transcriptional regulation of deoxynivalenol- induced IL-8 expression in human monocytes, Toxicol. Sci. 2007, 99, 502-511.
    • (2007) Toxicol. Sci. , vol.99 , pp. 502-511
    • Gray, J.S.1    Pestka, J.J.2
  • 20
    • 34548830788 scopus 로고    scopus 로고
    • Cytotoxicity, metabolism and cellular uptake of the mycotoxin deoxynivalenol in human proximal tubule cells and lung fibroblasts in primary culture
    • Koenigs, M., Lenczyk, M., Schwerdt, G., Holzinger, H., et al., Cytotoxicity, metabolism and cellular uptake of the mycotoxin deoxynivalenol in human proximal tubule cells and lung fibroblasts in primary culture, Toxicology 2007, 240, 48-59.
    • (2007) Toxicology , vol.240 , pp. 48-59
    • Koenigs, M.1    Lenczyk, M.2    Schwerdt, G.3    Holzinger, H.4
  • 21
    • 48449099149 scopus 로고    scopus 로고
    • Hypo-responsiveness of interleukin- 8 production in human embryonic epithelial intestine 407 cells independent of NF-jB pathway: New lessons from endotoxin and ribotoxic deoxynivalenol
    • Moon, Y., Yang, H., Park, S., Hypo-responsiveness of interleukin- 8 production in human embryonic epithelial intestine 407 cells independent of NF-jB pathway: New lessons from endotoxin and ribotoxic deoxynivalenol, Toxicol. Appl. Pharmacol. 2008, 231, 94-102.
    • (2008) Toxicol. Appl. Pharmacol. , vol.231 , pp. 94-102
    • Moon, Y.1    Yang, H.2    Park, S.3
  • 22
    • 34548247181 scopus 로고    scopus 로고
    • Modulation of early growth response gene I and interieukin-8 expression by ribotoxin deoxynivalenol (vomitoxin) via ERK1/2 in human epithelial intestine 407 cells
    • Moon, Y., Yang, H., Lee, S. H., Modulation of early growth response gene I and interieukin-8 expression by ribotoxin deoxynivalenol (vomitoxin) via ERK1/2 in human epithelial intestine 407 cells, Biochem. Biophys. Res. Commun. 2007, 362, 256-262.
    • (2007) Biochem. Biophys. Res. Commun. , vol.362 , pp. 256-262
    • Moon, Y.1    Yang, H.2    Lee, S.H.3
  • 23
    • 33745044469 scopus 로고    scopus 로고
    • Deoxynivalenol transport across human intestinal Caco-2 cells and its effects on cellular metabolism at realistic intestinal concentrations
    • Sergent, T., Parys, M., Garsou, S., Pussemier, L., et al., Deoxynivalenol transport across human intestinal Caco-2 cells and its effects on cellular metabolism at realistic intestinal concentrations, Toxicol. Lett. 2006, 164, 167-176.
    • (2006) Toxicol. Lett. , vol.164 , pp. 167-176
    • Sergent, T.1    Parys, M.2    Garsou, S.3    Pussemier, L.4
  • 25
    • 33745225162 scopus 로고    scopus 로고
    • Influence of diets with cereal grains contaminated by graded levels of two Fusarium toxins on selected enzymatic and histological parameters of liver in gilts
    • Tiemann, U., Brussow, K. P., Kuchenmeister, U., Jonas, L., et al., Influence of diets with cereal grains contaminated by graded levels of two Fusarium toxins on selected enzymatic and histological parameters of liver in gilts, Food Chem. Toxicol. 2006, 44, 1228-1235.
    • (2006) Food Chem. Toxicol. , vol.44 , pp. 1228-1235
    • Tiemann, U.1    Brussow, K.P.2    Kuchenmeister, U.3    Jonas, L.4
  • 26
    • 40949093147 scopus 로고    scopus 로고
    • Changes in the spleen and liver of pregnant sows and fullterm piglets after feeding diets naturally contaminated with deoxynivalenol and zearalenone
    • Tiemann, U., Brussow, K. P., Muchenmeister, U., Jonas, L., et al., Changes in the spleen and liver of pregnant sows and fullterm piglets after feeding diets naturally contaminated with deoxynivalenol and zearalenone, Vet. J. 2008, 176, 188-196.
    • (2008) Vet. J. , vol.176 , pp. 188-196
    • Tiemann, U.1    Brussow, K.P.2    Muchenmeister, U.3    Jonas, L.4
  • 27
    • 53249108147 scopus 로고    scopus 로고
    • Effects of the mycotoxin deoxynivalenol on human primary hepatocytes
    • Konigs, M., Schwerdt, G., Gekle, M., Humpf, H. U., Effects of the mycotoxin deoxynivalenol on human primary hepatocytes, Mol. Nutr. Food Res. 2008, 52, 830-839.
    • (2008) Mol. Nutr. Food Res. , vol.52 , pp. 830-839
    • Konigs, M.1    Schwerdt, G.2    Gekle, M.3    Humpf, H.U.4
  • 28
    • 49649126090 scopus 로고    scopus 로고
    • Rat liver clone-9 cells in culture as a model for screening hepatotoxic potential of food-related products: Hepatotoxicity of deoxynivalenol
    • Sahu, S. C., Garthoff, L., Robl, R., Chirtel, S., et al., Rat liver clone-9 cells in culture as a model for screening hepatotoxic potential of food-related products: Hepatotoxicity of deoxynivalenol, J. Appl. Toxicol. 2008, 28, 765-772.
    • (2008) J. Appl. Toxicol. , vol.28 , pp. 765-772
    • Sahu, S.C.1    Garthoff, L.2    Robl, R.3    Chirtel, S.4
  • 29
    • 0021222728 scopus 로고
    • Toxicological features of T-2 toxin and related trichothecenes
    • Ueno, Y., Toxicological features of T-2 toxin and related trichothecenes, Fundam. Appl. Toxicol. 1984, 4, S124-S132.
    • (1984) Fundam. Appl. Toxicol. , vol.4
    • Ueno, Y.1
  • 30
    • 4444268646 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: Unraveling a paradox
    • Pestka, J. J., Zhou, H. R., Moon, Y., Chung, Y. J., Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: Unraveling a paradox, Toxicol. Lett. 2004, 153, 61-73.
    • (2004) Toxicol. Lett. , vol.153 , pp. 61-73
    • Pestka, J.J.1    Zhou, H.R.2    Moon, Y.3    Chung, Y.J.4
  • 31
    • 0033553563 scopus 로고    scopus 로고
    • Trichothecene mycotoxins trigger a ribotoxic stress response that activates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase and induces apoptosis
    • Shifrin, V. I., Anderson, P., Trichothecene mycotoxins trigger a ribotoxic stress response that activates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase and induces apoptosis, J. Biol. Chem. 1999, 274, 13985-13992.
    • (1999) J. Biol. Chem. , vol.274 , pp. 13985-13992
    • Shifrin, V.I.1    Anderson, P.2
  • 32
    • 0034656052 scopus 로고    scopus 로고
    • Apoptosis induction by the satratoxins and other trichothecene mycotoxins: Relationship to ERK, p38 MARK, and SAP/JNK activation
    • Yang, G. H., Jarvis, B. B., Chung, Y. J., Pestka, J. J., Apoptosis induction by the satratoxins and other trichothecene mycotoxins: Relationship to ERK, p38 MARK, and SAP/JNK activation, Toxicol. Appl. Pharmacol. 2000, 164, 149-160.
    • (2000) Toxicol. Appl. Pharmacol. , vol.164 , pp. 149-160
    • Yang, G.H.1    Jarvis, B.B.2    Chung, Y.J.3    Pestka, J.J.4
  • 33
    • 0041589432 scopus 로고    scopus 로고
    • Role of double-stranded RNA-activated protein kinase R (PKR) in deoxynivalenolinduced ribotoxic stress response
    • Zhou, H. R., Lau, A. S., Pestka, J. J., Role of double-stranded RNA-activated protein kinase R (PKR) in deoxynivalenolinduced ribotoxic stress response. Toxicol. Sci. 2003, 74, 335-344.
    • (2003) Toxicol. Sci. , vol.74 , pp. 335-344
    • Zhou, H.R.1    Lau, A.S.2    Pestka, J.J.3
  • 34
    • 0034072727 scopus 로고    scopus 로고
    • Molecular determinants of apoptosis induced by the cytotoxic ribonuclease onconase: Evidence for cytotoxic mechanisms different from inhibition of protein synthesis
    • Iordanov, M. S., Ryabinina, O. P., Wong, J., Dinh, T. H., et al., Molecular determinants of apoptosis induced by the cytotoxic ribonuclease onconase: Evidence for cytotoxic mechanisms different from inhibition of protein synthesis. Cancer Res. 2000, 60, 1983-1994.
    • (2000) Cancer Res. , vol.60 , pp. 1983-1994
    • Iordanov, M.S.1    Ryabinina, O.P.2    Wong, J.3    Dinh, T.H.4
  • 35
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang, L. F., Karin, M., Mammalian MAP kinase signalling cascades, Nature 2001, 410, 37-40.
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.F.1    Karin, M.2
  • 36
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • Johnson, G. L., Lapadat, R., Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases, Science 2002, 298, 1911-1912.
    • (2002) Science , vol.298 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 37
    • 0036772512 scopus 로고    scopus 로고
    • Vomitoxin-induced cyclooxygenase-2 gene expression in macrophages mediated by activation of ERK and p38 but not JNK mitogen-activated protein kinases
    • Moon, Y., Pestka, J. J., Vomitoxin-induced cyclooxygenase-2 gene expression in macrophages mediated by activation of ERK and p38 but not JNK mitogen-activated protein kinases, Toxicol. Sci. 2002, 69, 373-382.
    • (2002) Toxicol. Sci. , vol.69 , pp. 373-382
    • Moon, Y.1    Pestka, J.J.2
  • 38
    • 0037342456 scopus 로고    scopus 로고
    • Rapid, sequential activation of mitogen-activated protein kinases and transcription factors precedes proinflammatory cytokine mRNA expression in spleens of mice exposed to the trichothecene vomitoxin
    • Zhou, H. R., Islam, Z., Pestka, J. J., Rapid, sequential activation of mitogen-activated protein kinases and transcription factors precedes proinflammatory cytokine mRNA expression in spleens of mice exposed to the trichothecene vomitoxin, Toxicol. Sci. 2003, 72, 130-142.
    • (2003) Toxicol. Sci. , vol.72 , pp. 130-142
    • Zhou, H.R.1    Islam, Z.2    Pestka, J.J.3
  • 39
    • 4444339687 scopus 로고    scopus 로고
    • Deoxynivalenol-induced apoptosis mediated by p38 mapk-dependent p53 gene induction in raw 264.7 macrophages
    • Zhou, H., Pestka, J. J., Deoxynivalenol-induced apoptosis mediated by p38 mapk-dependent p53 gene induction in raw 264.7 macrophages, Toxicol. Sci. 2003, 72, 330-330.
    • (2003) Toxicol. Sci. , vol.72 , pp. 330-330
    • Zhou, H.1    Pestka, J.J.2
  • 40
    • 12844262899 scopus 로고    scopus 로고
    • Truncated deoxynivalenol- induced splenic immediate early gene response in mice consuming (n-3) polyunsaturated fatty acids
    • Kinser, S., Li, M. X., Jia, Q. S., Pestka, J. J., Truncated deoxynivalenol- induced splenic immediate early gene response in mice consuming (n-3) polyunsaturated fatty acids. J. Nutr. Biochem. 2005, 16, 88-95.
    • (2005) J. Nutr. Biochem. , vol.16 , pp. 88-95
    • Kinser, S.1    Li, M.X.2    Jia, Q.S.3    Pestka, J.J.4
  • 41
    • 0035971493 scopus 로고    scopus 로고
    • AP-1 in cell proliferation and survival
    • Shaulian, E., Karin, M., AP-1 in cell proliferation and survival, Oncogene 2001, 20, 2390-2400.
    • (2001) Oncogene , vol.20 , pp. 2390-2400
    • Shaulian, E.1    Karin, M.2
  • 42
    • 0036098552 scopus 로고    scopus 로고
    • AP-1 as a regulator of cell life and death
    • Shaulian, E., Karin, M., AP-1 as a regulator of cell life and death, Nat. Cell Biol. 2002, 4, E131-E136.
    • (2002) Nat. Cell Biol. , vol.4
    • Shaulian, E.1    Karin, M.2
  • 43
    • 4444248155 scopus 로고    scopus 로고
    • Gene expression profiling in spleens of deoxynivalenol-exposed mice: Immediate early genes as primary targets
    • Kinser, S., Jia, Q. S., Li, M. X., Laughter, A., et al., Gene expression profiling in spleens of deoxynivalenol-exposed mice: Immediate early genes as primary targets, J. Toxicol. Environ. Health B Crit. Issues 2004, 67, 1423-1441.
    • (2004) J. Toxicol. Environ. Health B Crit. Issues , vol.67 , pp. 1423-1441
    • Kinser, S.1    Jia, Q.S.2    Li, M.X.3    Laughter, A.4
  • 44
    • 33846551201 scopus 로고    scopus 로고
    • The regulation of ATF3 gene expression by mitogen-activated protein kinases
    • Lu, D., Chen, J., Hai, T., The regulation of ATF3 gene expression by mitogen-activated protein kinases, Biochem. J. 2007, 401, 559-567.
    • (2007) Biochem. J. , vol.401 , pp. 559-567
    • Lu, D.1    Chen, J.2    Hai, T.3
  • 45
    • 0035948624 scopus 로고    scopus 로고
    • The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: Activating transcription factor proteins and homeostasis
    • Hai, T., Hartman, M. G., The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: Activating transcription factor proteins and homeostasis, Gene 2001, 273, 1-11.
    • (2001) Gene , vol.273 , pp. 1-11
    • Hai, T.1    Hartman, M.G.2
  • 46
    • 0025859448 scopus 로고
    • Induction of LRF- 1, a leucine-zipper protein that is rapidly and highly induced in regenerating liver
    • Hsu, J. C., Laz, T., Mohn, K. L., Taub, R., Induction of LRF- 1, a leucine-zipper protein that is rapidly and highly induced in regenerating liver, Proc. Natl. Acad. Sci. USA 1991, 88, 3511-3515.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 3511-3515
    • Hsu, J.C.1    Laz, T.2    Mohn, K.L.3    Taub, R.4
  • 47
    • 24044440971 scopus 로고    scopus 로고
    • BiNGO: A Cytoscape plugin to assess overrepresentation of Gene Ontology categories in Biological Networks
    • Maere, S., Heymans, K., Kuiper, M., BiNGO: A Cytoscape plugin to assess overrepresentation of Gene Ontology categories in Biological Networks, Bioinformatics 2005, 21, 3448-3449.
    • (2005) Bioinformatics , vol.21 , pp. 3448-3449
    • Maere, S.1    Heymans, K.2    Kuiper, M.3
  • 48
    • 38449101120 scopus 로고    scopus 로고
    • Integration of biological networks and gene expression data using Cytoscape
    • Cline, M. S., Smoot, M., Cerami, E., Kuchinsky, A., et al., Integration of biological networks and gene expression data using Cytoscape, Nat. Protoc. 2007, 2, 2366-2382.
    • (2007) Nat. Protoc. , vol.2 , pp. 2366-2382
    • Cline, M.S.1    Smoot, M.2    Cerami, E.3    Kuchinsky, A.4
  • 49
    • 0028224043 scopus 로고
    • Comparison of sulfur amino-acid ultization for GSH synthesis between HepG2 cells and cultured rat hepatocytes
    • Lu, S. C., Huang, H. Y., Comparison of sulfur amino-acid ultization for GSH synthesis between HepG2 cells and cultured rat hepatocytes, Biochem. Pharmacol. 1994, 47, 859-869.
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 859-869
    • Lu, S.C.1    Huang, H.Y.2
  • 50
    • 0032402090 scopus 로고    scopus 로고
    • Humanderived cell lines to study xenobiotic metabolism
    • Urani, C., Doldi, M., Crippa, S., Camatini, M., Humanderived cell lines to study xenobiotic metabolism, Chemosphere 1998, 37, 2785-2795.
    • (1998) Chemosphere , vol.37 , pp. 2785-2795
    • Urani, C.1    Doldi, M.2    Crippa, S.3    Camatini, M.4
  • 51
    • 0025679002 scopus 로고
    • Immediateearly gene-expression differs between regenerating liver, insulin-stimulated H-35 cells, and mitogen-stimulated BALB/C 3T3 cells-liver-specific induction-patterns of gene- 33, phosphoenolpyruvate carboxykinase, and the JUN, FOS, and EGR families
    • Mohn, K. L., Laz, T. M., Melby, A. E., Taub, R., Immediateearly gene-expression differs between regenerating liver, insulin-stimulated H-35 cells, and mitogen-stimulated BALB/C 3T3 cells-liver-specific induction-patterns of gene- 33, phosphoenolpyruvate carboxykinase, and the JUN, FOS, and EGR families, J. Biol. Chem. 1990, 265, 21914-21921.
    • (1990) J. Biol. Chem. , vol.265 , pp. 21914-21921
    • Mohn, K.L.1    Laz, T.M.2    Melby, A.E.3    Taub, R.4
  • 52
    • 36749084608 scopus 로고    scopus 로고
    • Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1-dependent expression of inducible nitric oxide synthase
    • Hasselblatt, P., Rath, M., Kominenovic, V., Zatloukal, K., Wagner, E. F., Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1-dependent expression of inducible nitric oxide synthase, Proc. Natl. Acad. Sci. USA 2007, 104, 17105-17110.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 17105-17110
    • Hasselblatt, P.1    Rath, M.2    Kominenovic, V.3    Zatloukal, K.4    Wagner, E.F.5
  • 53
    • 27144511258 scopus 로고    scopus 로고
    • Transcriptional regulation of activating transcription factor 3 involves the early growth response-1 gene
    • Bottone, F. G., Moon, Y., Alston-Mills, B., Eling, T. E., Transcriptional regulation of activating transcription factor 3 involves the early growth response-1 gene, J. Pharmacol. Exp. Ther. 2005, 315, 668-677.
    • (2005) J. Pharmacol. Exp. Ther. , vol.315 , pp. 668-677
    • Bottone, F.G.1    Moon, Y.2    Alston-Mills, B.3    Eling, T.E.4
  • 55
    • 0345687494 scopus 로고    scopus 로고
    • Transcriptional and posttranscriptional roles for p38 mitogen-activated protein kinase in upregulation of TNF-alpha expression by deoxynivalenol (vomitoxin)
    • Chung, Y. J., Zhou, H. R., Pestka, J. J., Transcriptional and posttranscriptional roles for p38 mitogen-activated protein kinase in upregulation of TNF-alpha expression by deoxynivalenol (vomitoxin),. Toxicol. Appl. Pharmacol. 2003, 193, 188-201.
    • (2003) Toxicol. Appl. Pharmacol. , vol.193 , pp. 188-201
    • Chung, Y.J.1    Zhou, H.R.2    Pestka, J.J.3
  • 56
    • 0036315395 scopus 로고    scopus 로고
    • The UV (ribotoxic) stress response of human keratinocytes involves the unexpected uncoupling of the Ras-extracellular signal-regulated kinase signaling cascade from the activated epidermal growth factor receptor
    • Iordanov, M. S., Choi, R. J., Ryabinina, O. P., Dinh, T. H., et al., The UV (ribotoxic) stress response of human keratinocytes involves the unexpected uncoupling of the Ras-extracellular signal-regulated kinase signaling cascade from the activated epidermal growth factor receptor, Mol. Cell. Biol. 2002, 22, 5380-5394.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5380-5394
    • Iordanov, M.S.1    Choi, R.J.2    Ryabinina, O.P.3    Dinh, T.H.4
  • 57
    • 0030973162 scopus 로고    scopus 로고
    • Ribotoxic stress response: Activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alphasarcin/ ricin loop in the 28S rRNA
    • Iordanov, M. S., Pribnow, D., Magun, J. L., Dinh, T. H., et al., Ribotoxic stress response: Activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alphasarcin/ ricin loop in the 28S rRNA, Mol. Cell. Biol. 1997, 17, 3373-3381.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3373-3381
    • Iordanov, M.S.1    Pribnow, D.2    Magun, J.L.3    Dinh, T.H.4
  • 58
    • 0032546791 scopus 로고    scopus 로고
    • Ultraviolet radiation triggers the ribotoxic stress response in mammalian cells
    • Iordanov, M. S., Pribnow, D., Magun, J. L., Dinh, T. H., et al., Ultraviolet radiation triggers the ribotoxic stress response in mammalian cells, J. Biol. Chem. 1998, 273, 15794-15803.
    • (1998) J. Biol. Chem. , vol.273 , pp. 15794-15803
    • Iordanov, M.S.1    Pribnow, D.2    Magun, J.L.3    Dinh, T.H.4
  • 59
    • 37049179817 scopus 로고
    • Early signals in the mitogenic response
    • Rozengurt, E., Early signals in the mitogenic response, Science 1986, 234, 161-166.
    • (1986) Science , vol.234 , pp. 161-166
    • Rozengurt, E.1
  • 60
    • 0345732643 scopus 로고    scopus 로고
    • A network of immediate early gene products propagates subtle differences in mitogen-activated protein kinase signal amplitude and duration
    • Murphy, L. O., MacKeigan, J. P., Blenis, J., A network of immediate early gene products propagates subtle differences in mitogen-activated protein kinase signal amplitude and duration, Mol. Cell. Biol. 2004, 24, 144-153.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 144-153
    • Murphy, L.O.1    Mackeigan, J.P.2    Blenis, J.3
  • 61
    • 0345150646 scopus 로고    scopus 로고
    • HCK- and PKR-dependent mitogenactivated protein kinase phosphorylation and AP-1, C/EBP and NF-KAPPAB activation precede deoxynivalenol-induced TNF-alpha and MIP-2 expression
    • Pestka, J. J., Zhou, H., HCK- and PKR-dependent mitogenactivated protein kinase phosphorylation and AP-1, C/EBP and NF-KAPPAB activation precede deoxynivalenol-induced TNF-alpha and MIP-2 expression, Toxicol. Sci. 2003, 72, 121-121.
    • (2003) Toxicol. Sci. , vol.72 , pp. 121-121
    • Pestka, J.J.1    Zhou, H.2
  • 63
    • 0036616351 scopus 로고    scopus 로고
    • Effects of sterigmatocystin, deoxynivalenol and aflatoxin G(1) on apoptosis of human peripheral blood lymphocytes in vitro'
    • Sun, X. M., Zhang, X. H., Wang, H. Y., Cao, W. J., et al., Effects of sterigmatocystin, deoxynivalenol and aflatoxin G(1) on apoptosis of human peripheral blood lymphocytes in vitro', Biomed. Environ. Sci. 2002, 15, 145-152.
    • (2002) Biomed. Environ. Sci. , vol.15 , pp. 145-152
    • Sun, X.M.1    Zhang, X.H.2    Wang, H.Y.3    Cao, W.J.4
  • 64
    • 0031172809 scopus 로고    scopus 로고
    • Differential cytokine mRNA expression in mice after oral exposure to the trichothecene vomitoxin (deoxynivalenol): Dose response and time course
    • Zhou, H. R., Yan, D., Pestka, J. J., Differential cytokine mRNA expression in mice after oral exposure to the trichothecene vomitoxin (deoxynivalenol): Dose response and time course, Toxicol. Appl. Pharmacol. 1997, 144, 294-305.
    • (1997) Toxicol. Appl. Pharmacol. , vol.144 , pp. 294-305
    • Zhou, H.R.1    Yan, D.2    Pestka, J.J.3
  • 65
    • 0034652267 scopus 로고    scopus 로고
    • Modulation of transcription factor AP-1 activity in murine EL-4 thymoma cells by vomitoxin (deoxynivalenol)
    • Li, S. G., Ouyang, Y. L., Yang, G. H., Pestka, J. J., Modulation of transcription factor AP-1 activity in murine EL-4 thymoma cells by vomitoxin (deoxynivalenol), Toxicol. Appl. Pharmacol. 2000, 163, 17-25.
    • (2000) Toxicol. Appl. Pharmacol. , vol.163 , pp. 17-25
    • Li, S.G.1    Ouyang, Y.L.2    Yang, G.H.3    Pestka, J.J.4
  • 66
    • 20544450139 scopus 로고    scopus 로고
    • Ribotoxic stress response to the trichothecene deoxynivalenol in the macrophage involves the Src family kinase Hck
    • Zhou, H. R., Jia, Q. S., Pestka, J. J., Ribotoxic stress response to the trichothecene deoxynivalenol in the macrophage involves the Src family kinase Hck, Toxicol. Sci. 2005, 85, 916-926.
    • (2005) Toxicol. Sci. , vol.85 , pp. 916-926
    • Zhou, H.R.1    Jia, Q.S.2    Pestka, J.J.3
  • 67
    • 65749088806 scopus 로고    scopus 로고
    • Hepatocyte survival in acute hepatitis is due to C-Jun/AP-1-dependent expression of inducible nitric oxide synthase
    • Hasselblatt, P., Rath, M., Komnenovic, V., Zatloukal, K., Wagner, E., Hepatocyte survival in acute hepatitis is due to C-Jun/AP-1-dependent expression of inducible nitric oxide synthase, Hepatology 2007, 46, 690A-691A.
    • (2007) Hepatology , vol.46
    • Hasselblatt, P.1    Rath, M.2    Komnenovic, V.3    Zatloukal, K.4    Wagner, E.5
  • 68
    • 0036338347 scopus 로고    scopus 로고
    • Effects of vomitoxin (deoxynivalenol) on the binding of transcription factors AP- 1, NF-kappa B, and NF-IL6 in raw 264.7 macrophage cells
    • Wong, S. S., Zhou, H. R., Pestka, J. J., Effects of vomitoxin (deoxynivalenol) on the binding of transcription factors AP- 1, NF-kappa B, and NF-IL6 in raw 264.7 macrophage cells, J. Toxicol. Environ. Health Part A 2002, 65, 1161-1180.
    • (2002) J. Toxicol. Environ. Health Part A , vol.65 , pp. 1161-1180
    • Wong, S.S.1    Zhou, H.R.2    Pestka, J.J.3
  • 69
    • 0036051342 scopus 로고    scopus 로고
    • Molecular interpretation of ERK signal duration by immediate early gene products
    • Murphy, L. O., Smith, S., Chen, R. H., Fingar, D. C., Blenis, J., Molecular interpretation of ERK signal duration by immediate early gene products, Nat. Cell Biol. 2002, 4, 556-564.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 556-564
    • Murphy, L.O.1    Smith, S.2    Chen, R.H.3    Fingar, D.C.4    Blenis, J.5
  • 70
    • 23044439446 scopus 로고    scopus 로고
    • Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation
    • Tamura, K., Hua, B. Y., Adachi, S., Guney, I., et al., Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation, EMBO J. 2005, 24, 2590-2601.
    • (2005) EMBO J. , vol.24 , pp. 2590-2601
    • Tamura, K.1    Hua, B.Y.2    Adachi, S.3    Guney, I.4
  • 71
    • 0033118409 scopus 로고    scopus 로고
    • Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response
    • Fawcett, T. W., Martindale, J. L., Guyton, K. Z., Hai, T., Holbrook, N. J., Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response, Biochem. J. 1999, 339, 135-141.
    • (1999) Biochem. J. , vol.339 , pp. 135-141
    • Fawcett, T.W.1    Martindale, J.L.2    Guyton, K.Z.3    Hai, T.4    Holbrook, N.J.5
  • 72
    • 0038452604 scopus 로고    scopus 로고
    • Expression of the activating transcription factor 3 prevents c-Jun N-terminal kinase-induced neuronal death by promoting heat shock protein 27 expression and Akt activation
    • Nakagomi, S., Suzuki, Y., Namikawa, K., Kiryu-Seo, S., Kiyama, H., Expression of the activating transcription factor 3 prevents c-Jun N-terminal kinase-induced neuronal death by promoting heat shock protein 27 expression and Akt activation, J. Neurosci. 2003, 23, 5187-5196.
    • (2003) J. Neurosci. , vol.23 , pp. 5187-5196
    • Nakagomi, S.1    Suzuki, Y.2    Namikawa, K.3    Kiryu-Seo, S.4    Kiyama, H.5
  • 73
    • 0842324003 scopus 로고    scopus 로고
    • TNF alpha-induced ATF3 expression is bidirectionally regulated by the JNK and ERK pathways in vascular endothelial cells
    • Inoue, K., Zama, T., Kamimoto, T., Aoki, R. et al., TNF alpha-induced ATF3 expression is bidirectionally regulated by the JNK and ERK pathways in vascular endothelial cells, Genes Cells 2004, 9, 59-70.
    • (2004) Genes Cells , vol.9 , pp. 59-70
    • Inoue, K.1    Zama, T.2    Kamimoto, T.3    Aoki, R.4
  • 74
    • 0037205462 scopus 로고    scopus 로고
    • The roles of ATF3 in liver dysfunction and the regulation of phosphoenolpyruvate carboxykinase gene expression
    • Allen-Jennings, A. E., Hartman, M. G., Kociba, G. J., Hai, T. W., The roles of ATF3 in liver dysfunction and the regulation of phosphoenolpyruvate carboxykinase gene expression, J. Biol. Chem. 2002, 277, 20020-20025.
    • (2002) J. Biol. Chem. , vol.277 , pp. 20020-20025
    • Allen-Jennings, A.E.1    Hartman, M.G.2    Kociba, G.J.3    Hai, T.W.4


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