Subacute effects of moderate feed loads of isolated Fusarium toxin deoxynivalenol on selected parameters of metabolism in weaned growing piglets

Journal of Animal Physiology and Animal Nutrition

Volumn 90, Issue 9-10, 2006, Pages 421-428

  Drochner, W ^a   Schollenberger, M ^a   Gotz S ^a   Lauber, U ^a   Tafaj, M ^a   Piepho, H P ^a  

^a UNIVERSITY OF HOHENHEIM   (Germany)

Author keywords

Aspartate aminotransferase; Growing piglets; Haemoglobin; Pure deoxynivalenol; Ratio glucose urea

Indexed keywords

ASPARTATE AMINOTRANSFERASE; NITROGEN; SERUM ALBUMIN; TRICHOTHECENE DERIVATIVE; VOMITOXIN;

AGE; ANIMAL; ANIMAL FOOD; ARTICLE; BLOOD; BODY WEIGHT; DOSE RESPONSE; DRUG EFFECT; ENERGY METABOLISM; ENZYMOLOGY; FEMALE; FOOD CONTAMINATION; GLUCOSE BLOOD LEVEL; GROWTH, DEVELOPMENT AND AGING; HEMATOPOIESIS; LIVER; METABOLISM; SWINE; UREA NITROGEN BLOOD LEVEL; WEANING;

AGE FACTORS; ANIMAL FEED; ANIMALS; ASPARTATE AMINOTRANSFERASES; BLOOD GLUCOSE; BLOOD UREA NITROGEN; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; FEMALE; FOOD CONTAMINATION; HEMATOPOIESIS; LIVER; NITROGEN; SERUM ALBUMIN; SWINE; TRICHOTHECENES; WEANING;

ANIMALIA; FUSARIUM; SUS SCROFA;

EID: 33748354034     PISSN: 09312439     EISSN: 14390396     Source Type: Journal    
DOI: 10.1111/j.1439-0396.2006.00622.x     Document Type: Article

References (35)

1. Bergsjoe, B.; Langseth, W.; Nafstad, I.; Hoegset Jansen, J.; Larsen, H. J. S., 1993: The effects of naturally deoxynivalenol-contaminated oats on the clinical conditions, blood parameters, performance and carcass composition of growing pigs. Veterinary Research Communications 17, 283-294.
2. BML. The German Federal Ministry of Nutrition, Agriculture and Forestry, 2000: Rundschreiben des BML vom 30. 06. 2000-324-3830/323. http://www. verbrauchermin-000547AB02421075B2886521C0A8D816.html.
3. Chang, I. M.; Mar, W. C., 1988: Effect of T-2 toxin on lipid peroxidation in rats: elevation of conjugated diene formation. Toxicology Letters 40, 275-280.
4. Dänicke, S.; Valenta, H.; Doll, S., 2004: On the toxicokinetics and the metabolism of deoxynivalenol (DON) in the pig. Archves of Animal Nutrition 58, 169-180.
5. Dial, S. M., 1995: Clinicopathological evaluation of the liver. Small Animal Practice 25, 257-273.
6. Diggle, P. J.; Liang, K.-Y.; Zeger, S. L., 1994: Analysis of longitudinal data. Clarendon Press, Oxford.
7. Drochner, W., 1977: Auswirkungen parenteraler und oraler (Trinkwasser) kombinierter Eisen-/Kupfergaben auf Gewichtsentwicklung, Bluthä moglobingehalt, Caeruloplasminkonzentration im Serum und Katalaseaktivität der Erythrozyten von Saugferkeln. Deutsche Tierärztliche Wochenschrift 84, 300-305.
8. Drochner, W.; Schollenberger, M.; Piepho, H.-P.; Götz, S.; Lauber, U.; Tafaj, M.; Klobasa, F.; Weiler, U.; Claus, R.; Steffl, M., 2004: Serum IgA-promoting effects induced by feed loads containing isolated deoxynivalenol (DON) in growing piglets. Journal of Toxicology and Environmental Health A, 67, 1051-1067.
9. Federal Council of Germany, 2005: Verordnung über Höchstmengen an Mykotoxinen und weiteren Kontaminanten in Lebensmitteln und zur Änderung oder Aufhebung anderer Lebensmittelrechtlicher Verordnungen. Drucksache 224/05.
10. Feinberg, B.; McLaughlin, C. S., 1989: In: Trichothecene mycotoxicosis: Pathophysiological effects, Vol. I ed. V. R. Beasley, CRC Press, Florida, 27.
11. Foster, B. C.; Trenholm, H. L.; Friend, D. W.; Thompson, B. K.; Hartin, K. E., 1986: Evaluation of different sources of deoxynivalenol (vomitoxin) fed to swine. Canadian Journal of Animal Science 66, 1149-1154.
12. Froquet, R.; Arnold, F.; Batin, A. B.; Parent-Massin, D., 2003: Do trichothecenes reduce viability of circulating blood cells and modify haemostasis parameters? Mycopathologia 156, 349-356.
13. Hauptman, K., Tichy, F., Knotek, Z., 2001: Clinical diagnostics of hepatopathies in small mammals: Evaluation of importance of individual methods. Acta Veterinaria 70, 297-311.
14. Joint FAO/WHO Expert Committee on Food Additives (JECFA), 2001: Safety evaluation of certain mycotoxins in food. Deoxynivalenol, HT-2 and T-2 toxin. FAO Food and Nutrition paper 74.
15. Kenward, M. G.; Roger, J. H., 1997: Small sample inference for fixed effects from restricted maximum likelihood. Biometrics 53, 983-997.
16. Klobasa, F.; Habe, F.; Werhahn, E., 1983: Immunglobulin-Konzentrationen im Blutserum von Sauen. Landdbauforschung Völkenrode 33, 243-250.
17. Klobasa, F., 1987: Methodische und gerätetechnische Probleme und Erfahrungen bei der Anwendung immunologischer Verfahren in der Tierzuchtforschung. Landbauforschung Völkenrode 37, 1-17.
18. Kubena, L. F.; Huff, W. E.; Harvey, R. B.; Corrier, T. D.; Creger, C. R., 1989: Individual and combined toxicity of deoxynivalenol and T-2 toxin in broiler chicks. Poultry Science 68, 622-626.
19. Littell, R. C.; Henry, P. R.; Ammerman, C. B., 1998: Statistical analysis of repeated measures data using SAS procedures. Journal of Animal Science, 76, 1216-1231.
20. Meloche, J. L.; Smith, T. K., 1995: Altered tissue amino acid metabolism in acute T-2 toxicosis. Proceedings of the Society for Experimental Biology and Medicine 210, 260-269.
21. Parent-Massin, D; Parchment, R. E., 1998: Haematotoxicity of mycotoxins. Revue de Médecine Vétérinaire 149, 591-598.
22. Plonait, H.; Bickardt, K., 1988: Lehrbuch der Schweinekrankheiten. Paul Parey Verlag, Berlin, Hamburg.
23. Rio, B.; Lautraite, S.; Parent Massin, D., 1997: In Vitro toxicity of trichothecenes on human erythroblastic progenitors. Human and Experimental Toxicology 16, 673-679.
24. Rizzo, A. F.; Atroshi, F.; Hirvi, T.; Saloniemi, H., 1992: The hemolytic activity of deoxynivalenol and T-2 toxin. Natural Toxins 1, 106-110.
25. Rotter, B. A.; Thompson, B. K.; Lessard, M., 1995: Effects of deoxynivalenol-contaminated diet on performance and blood parameters in growing pig. Canadian Journal of Animal Science 75, 297-302.
26. Rotter, B.A.; Prelusky, D.B.; Pestka, J.J., 1996: Toxicology of deoxynivalenol (vomitoxin). Journal of Toxicology and Environmental Health 48, 1-34.
27. Schollenberger, M.; Lauber, U.; Terry, H.; Suchy, S.; Drochner, W., Müller, H.-M., 1998: Determination of eight trichothecenes by gas chromatography-mass spectroscopy after sample clean-up by a two stage solid-phase extraction. Journal of Chromatography A, 815, 123-132.
28. Schollenberger, M.; Suchy, S.; Terry-Jara, H.; Drochner, W.; Müller, H.-M., 1999: A survey of Fusarium toxins in cereal-based foods marketed in an area of southwest Germany. Mycopathologia 147, 49-57.
29. Smith, T. K., 1992: Recent advances in the understanding of Fusarium trichothecene mycotoxicoses. Journal of Animal Science 70, 3989-3993.
30. Suneja, S. K.; Ram, G. C.; Wagle, D.S., 1984: Effect of T-2 administration to rats on lipid metabolism in liver. Toxicology Letters 22, 113-118.
31. Swamy, H. V. L. N.; Smith, T. K.; Cotter, P. F.; Boermans, H. J.; Sefton, A. E., 2003: Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on production and metabolism in broilers. Poultry Science 81, 966.
32. Tashiro, F.; Hiral, K.; Ueno, Y., 1979: Inhibitory effects of carcinogenic mycotoxins on deoxyribonucleic acid-dependent ribonucleic acid polymerase and ribonuclease H. Journal of Applied and Environmental Microbiology 38, 191-196.
33. Trenholm, H. L.; Foster, B. C.; Charmley, L. L.; Thompson, B. K., 1994: Effects of feeding diets containing Fusarium (naturally) contaminated wheat or pure deoxynivalenol (DON) in growing pigs. Canadian Journal of Animal Science 74, 361-369.
34. Verbeke, G.; Molenberghs, G., eds. 1997: Linear mixed models in practice. A SAS-oriented approach. Springer, Berlin.
35. Wolfinger, R. D., 1996: Heterogeneous variance-covariance structures for repeated measures. Journal of Agricultural Biology and Environmental Science 1, 205-230.