Cytotoxicity, metabolism and cellular uptake of the mycotoxin deoxynivalenol in human proximal tubule cells and lung fibroblasts in primary culture

Toxicology

Volumn 240, Issue 1-2, 2007, Pages 48-59

  Königs, Maika ^a   Lenczyk, Marlies ^a   Schwerdt, Gerald ^c   Holzinger, Hildegard ^b   Gekle, Michael ^c   Humpf, Hans Ulrich ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Apoptosis; Cellular uptake; Cytotoxicity; Human; Lung fibroblasts; Metabolism; Mycotoxin deoxynivalenol; Necrosis; Primary culture; Proximal tubule cells

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 4; FIBRONECTIN; MYCOTOXIN; MYCOTOXIN DEOXYNIVALENOL; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL IMMORTALIZATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DIARRHEA; DIGESTIVE SYSTEM INFLAMMATION; EXPOSURE; HUMAN; HUMAN CELL; IMMUNE SYSTEM; KIDNEY INJURY; KIDNEY PROXIMAL TUBULE; LIQUID CHROMATOGRAPHY; LUNG FIBROBLAST; LUNG TOXICITY; MASS SPECTROMETRY; METABOLISM; NEPHROTOXICITY; PRIORITY JOURNAL; PROTEIN SECRETION; TISSUE NECROSIS; VOMITING;

CASPASE 3; CELL COUNT; CELL SURVIVAL; CELLS, CULTURED; COLLAGEN; EPITHELIAL CELLS; FIBROBLASTS; FIBRONECTINS; HUMANS; KIDNEY TUBULES, PROXIMAL; LUNG; MICROSCOPY, FLUORESCENCE; NECROSIS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; TRICHOTHECENES;

ANIMALIA;

EID: 34548830788     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2007.07.016     Document Type: Article

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