메뉴 건너뛰기




Volumn 16, Issue 9, 2009, Pages 1047-1061

MicroRNAs and lung cancer: New oncogenes and tumor suppressors, new prognostic factors and potential therapeutic targets

Author keywords

Cancer; Diagnosis; Lung; MicroRNA; Prognosis; Therapeutic target

Indexed keywords

ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; BEVASIRANIB; CONNECTIVE TISSUE GROWTH FACTOR; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DNA METHYLTRANSFERASE; ERLOTINIB; GEFITINIB; HIGH MOBILITY GROUP A2 PROTEIN; K RAS PROTEIN; MESSENGER RNA; MICRORNA; MYC PROTEIN; PACLITAXEL; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN P53; RAS PROTEIN; RETROVIRUS VECTOR; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; THROMBOSPONDIN 1; TRANSCRIPTION FACTOR E2F1; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 65649152994     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986709787581833     Document Type: Review
Times cited : (90)

References (176)
  • 1
    • 2142708114 scopus 로고    scopus 로고
    • A short history of a short RNA
    • 1 p following S96
    • Lee, R.; Feinbaum, R.; Ambros, V. A short history of a short RNA. Cell, 2004, 116, S89-92, 1 p following S96.
    • (2004) Cell , vol.116
    • Lee, R.1    Feinbaum, R.2    Ambros, V.3
  • 2
    • 0347444723 scopus 로고    scopus 로고
    • Genomics, biogenesis, mechanism, and function
    • Bartel, D. P. MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell, 2004, 116, 281-97.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.M.1
  • 3
    • 33644768174 scopus 로고    scopus 로고
    • Control of translation and mRNA degradation by miRNAs and siRNAs
    • Valencia-Sanchez, M. A.; Liu, J.; Hannon, G. J.; Parker, R. Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev., 2006, 20, 515-24.
    • (2006) Genes Dev , vol.20 , pp. 515-524
    • Valencia-Sanchez, M.A.1    Liu, J.2    Hannon, G.J.3    Parker, R.4
  • 4
    • 33846277696 scopus 로고    scopus 로고
    • Repression of protein synthesis by miRNAs: How many mechanisms?
    • Pillai, R. S.; Bhattacharyya, S. N.; Filipowicz, W. Repression of protein synthesis by miRNAs: How many mechanisms? Trends Cell Biol., 2007, 17, 118-26.
    • (2007) Trends Cell Biol , vol.17 , pp. 118-126
    • Pillai, R.S.1    Bhattacharyya, S.N.2    Filipowicz, W.3
  • 5
    • 0037009364 scopus 로고    scopus 로고
    • MicroRNA maturation: Stepwise processing and subcellular localization
    • Lee, Y.; Jeon, K.; Lee, J. T.; Kim, S.; Kim, V. N. MicroRNA maturation: stepwise processing and subcellular localization. EMBO J., 2002, 21, 4663-70.
    • (2002) EMBO J , vol.21 , pp. 4663-4670
    • Lee, Y.1    Jeon, K.2    Lee, J.T.3    Kim, S.4    Kim, V.N.5
  • 7
    • 9144224451 scopus 로고    scopus 로고
    • Processing of primary microRNAs by the Microprocessor complex
    • Denli, A. M.; Tops, B. B.; Plasterk, R. H.; Ketting, R. F.; Hannon, G. J. Processing of primary microRNAs by the Microprocessor complex. Nature, 2004, 432, 231-5.
    • (2004) Nature , vol.432 , pp. 231-235
    • Denli, A.M.1    Tops, B.B.2    Plasterk, R.H.3    Ketting, R.F.4    Hannon, G.J.5
  • 8
    • 34249810892 scopus 로고    scopus 로고
    • Argonaute proteins: Mediators of RNA silencing
    • Peters, L.; Meister, G. Argonaute proteins: Mediators of RNA silencing. Mol. Cell, 2007, 26, 611-23.
    • (2007) Mol. Cell , vol.26 , pp. 611-623
    • Peters, L.1    Meister, G.2
  • 9
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis, B. P.; Burge, C. B.; Bartel, D. P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell, 2005, 120, 15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 11
    • 1642374097 scopus 로고    scopus 로고
    • Specificity of microRNA target selection in translational repression
    • Doench, J. G.; Sharp, P. A. Specificity of microRNA target selection in translational repression. Genes Dev., 2004, 18, 504-11.
    • (2004) Genes Dev , vol.18 , pp. 504-511
    • Doench, J.G.1    Sharp, P.A.2
  • 12
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
    • Filipowicz, W.; Bhattacharyya, S. N.; Sonenberg, N. Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight? Nat. Rev. Genet., 2008, 9, 102-14.
    • (2008) Nat. Rev. Genet , vol.9 , pp. 102-114
    • Filipowicz, W.1    Bhattacharyya, S.N.2    Sonenberg, N.3
  • 13
    • 15244358503 scopus 로고    scopus 로고
    • Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals
    • Xie, X.; Lu, J.; Kulbokas, E. J.; Golub, T. R.; Mootha, V.; Lindblad-Toh, K.; Lander, E. S.; Kellis, M. Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals. Nature, 2005, 434, 338-45.
    • (2005) Nature , vol.434 , pp. 338-345
    • Xie, X.1    Lu, J.2    Kulbokas, E.J.3    Golub, T.R.4    Mootha, V.5    Lindblad-Toh, K.6    Lander, E.S.7    Kellis, M.8
  • 14
    • 33644750115 scopus 로고    scopus 로고
    • Griffiths-Jones, S.; Grocock, R. J.; van Dongen, S.; Bateman, A.; Enright, A. J. miRBase: MicroRNA sequences, targets and gene nomenclature. Nucleic Acids Res., 2006, 34, D140-4.
    • Griffiths-Jones, S.; Grocock, R. J.; van Dongen, S.; Bateman, A.; Enright, A. J. miRBase: MicroRNA sequences, targets and gene nomenclature. Nucleic Acids Res., 2006, 34, D140-4.
  • 16
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs - microRNAs with a role in cancer
    • Esquela-Kerscher, A.; Slack, F. J. Oncomirs - microRNAs with a role in cancer. Nat. Rev. Cancer, 2006, 6, 259-69.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 17
    • 41349099104 scopus 로고    scopus 로고
    • Jemal, A.; Siegel, R.; Ward, E.; Hao, Y.; Xu, J.; Murray, T.; Thun, M. J. Cancer statistics, 2008. CA Cancer J. Clin., 2008, 58, 71-96.
    • Jemal, A.; Siegel, R.; Ward, E.; Hao, Y.; Xu, J.; Murray, T.; Thun, M. J. Cancer statistics, 2008. CA Cancer J. Clin., 2008, 58, 71-96.
  • 18
    • 38349148694 scopus 로고    scopus 로고
    • Molecular biologic staging of lung cancer
    • D'Amico, T. A. Molecular biologic staging of lung cancer. Ann. Thorac. Surg., 2008, 85, S737-42.
    • (2008) Ann. Thorac. Surg , vol.85
    • D'Amico, T.A.1
  • 19
    • 34249861387 scopus 로고    scopus 로고
    • Prognostic modeling in early stage lung cancer: An evolving process from histopathology to genomics
    • viii
    • Harpole, D. H., Jr. Prognostic modeling in early stage lung cancer: An evolving process from histopathology to genomics. Thorac. Surg. Clin., 2007, 17, 167-73, viii.
    • (2007) Thorac. Surg. Clin , vol.17 , pp. 167-173
    • Harpole Jr., D.H.1
  • 21
    • 30344456035 scopus 로고    scopus 로고
    • Facile means for quantifying microRNA expression by real-time PCR
    • Shi, R.; Chiang, V. L. Facile means for quantifying microRNA expression by real-time PCR. Biotechniques, 2005, 39, 519-25
    • (2005) Biotechniques , vol.39 , pp. 519-525
    • Shi, R.1    Chiang, V.L.2
  • 23
    • 42049095870 scopus 로고    scopus 로고
    • MicroRNA expression profiling using microarrays
    • Liu, C. G.; Calin, G. A.; Volinia, S.; Croce, C. M. MicroRNA expression profiling using microarrays. Nat. Protoc., 2008, 3, 563-78.
    • (2008) Nat. Protoc , vol.3 , pp. 563-578
    • Liu, C.G.1    Calin, G.A.2    Volinia, S.3    Croce, C.M.4
  • 25
    • 16344383409 scopus 로고    scopus 로고
    • Development of a micro-array to detect human and mouse microRNAs and characterization of expression in human organs
    • Sun, Y.; Koo, S.; White, N.; Peralta, E.; Esau, C.; Dean, N. M.; Perera, R. J. Development of a micro-array to detect human and mouse microRNAs and characterization of expression in human organs. Nucleic Acids Res., 2004, 32, e188.
    • (2004) Nucleic Acids Res , vol.32
    • Sun, Y.1    Koo, S.2    White, N.3    Peralta, E.4    Esau, C.5    Dean, N.M.6    Perera, R.J.7
  • 26
    • 33845876339 scopus 로고    scopus 로고
    • Direct and sensitive miRNA profiling from low-input total RNA
    • Wang, H.; Ach, R. A.; Curry, B. Direct and sensitive miRNA profiling from low-input total RNA. RNA, 2007, 13, 151-9
    • (2007) RNA , vol.13 , pp. 151-159
    • Wang, H.1    Ach, R.A.2    Curry, B.3
  • 28
    • 33646178285 scopus 로고    scopus 로고
    • A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA)
    • Castoldi, M.; Schmidt, S.; Benes, V.; Noerholm, M.; Kulozik, A. E.; Hentze, M. W.; Muckenthaler, M. U. A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA). RNA, 2006, 12, 913-20.
    • (2006) RNA , vol.12 , pp. 913-920
    • Castoldi, M.1    Schmidt, S.2    Benes, V.3    Noerholm, M.4    Kulozik, A.E.5    Hentze, M.W.6    Muckenthaler, M.U.7
  • 30
    • 33748163981 scopus 로고
    • A microRNA detection system based on padlock probes and rolling circle amplification
    • Jonstrup, S. P.; Koch, J.; Kjems, J. A microRNA detection system based on padlock probes and rolling circle amplification. RNA, 2006, 12, 1747-52.
    • (1747) RNA , vol.2006 , pp. 12
    • Jonstrup, S.P.1    Koch, J.2    Kjems, J.3
  • 32
    • 34548682763 scopus 로고    scopus 로고
    • Analysis of microRNA expression by in situ hybridization with RNA oligonucleotide probes
    • Thompson, R. C.; Deo, M.; Turner, D. L. Analysis of microRNA expression by in situ hybridization with RNA oligonucleotide probes. Methods, 2007, 43, 153-61.
    • (2007) Methods , vol.43 , pp. 153-161
    • Thompson, R.C.1    Deo, M.2    Turner, D.L.3
  • 34
    • 31344454565 scopus 로고    scopus 로고
    • In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes
    • Kloosterman, W. P.; Wienholds, E.; de Bruijn, E.; Kauppinen, S.; Plasterk, R. H. In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes. Nat. Methods, 2006, 3, 27-9.
    • (2006) Nat. Methods , vol.3 , pp. 27-29
    • Kloosterman, W.P.1    Wienholds, E.2    de Bruijn, E.3    Kauppinen, S.4    Plasterk, R.H.5
  • 36
    • 31044455031 scopus 로고    scopus 로고
    • Nelson, P. T.; Baldwin, D. A.; Kloosterman, W. P.; Kauppinen, S.; Plasterk, R. H.; Mourelatos, Z. RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain. RNA, 2006, 12, 187-91.
    • Nelson, P. T.; Baldwin, D. A.; Kloosterman, W. P.; Kauppinen, S.; Plasterk, R. H.; Mourelatos, Z. RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain. RNA, 2006, 12, 187-91.
  • 38
    • 33748310866 scopus 로고    scopus 로고
    • Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides
    • Deo, M.; Yu, J. Y.; Chung, K. H.; Tippens, M.; Turner, D. L. Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides. Dev. Dyn., 2006, 235, 2538-48
    • (2006) Dev. Dyn , vol.235 , pp. 2538-2548
    • Deo, M.1    Yu, J.Y.2    Chung, K.H.3    Tippens, M.4    Turner, D.L.5
  • 39
    • 33745623128 scopus 로고    scopus 로고
    • Post-transcriptional regulation of microRNA expression
    • Obernosterer, G.; Leuschner, P. J.; Alenius, M.; Martinez, J. Post-transcriptional regulation of microRNA expression. RNA, 2006, 12, 1161-7.
    • (2006) RNA , vol.12 , pp. 1161-1167
    • Obernosterer, G.1    Leuschner, P.J.2    Alenius, M.3    Martinez, J.4
  • 43
    • 33748587841 scopus 로고    scopus 로고
    • A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes
    • Miranda, K. C.; Huynh, T.; Tay, Y.; Ang, Y. S.; Tam, W. L.; Thomson, A. M.; Lim, B.; Rigoutsos, I. A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes. Cell, 2006, 126, 1203-17.
    • (2006) Cell , vol.126 , pp. 1203-1217
    • Miranda, K.C.1    Huynh, T.2    Tay, Y.3    Ang, Y.S.4    Tam, W.L.5    Thomson, A.M.6    Lim, B.7    Rigoutsos, I.8
  • 44
    • 1542297345 scopus 로고    scopus 로고
    • Computational identification of microRNA targets
    • Rajewsky, N.; Socci, N. D. Computational identification of microRNA targets. Dev. Biol., 2004, 267, 529-35.
    • (2004) Dev. Biol , vol.267 , pp. 529-535
    • Rajewsky, N.1    Socci, N.D.2
  • 45
    • 33745248430 scopus 로고    scopus 로고
    • Rajewsky, N. microRNA target predictions in animals. Nat. Genet., 2006, 38 Suppl, S8-13.
    • Rajewsky, N. microRNA target predictions in animals. Nat. Genet., 2006, 38 Suppl, S8-13.
  • 48
    • 37049002638 scopus 로고    scopus 로고
    • Vigorito, E.; Perks, K. L.; Abreu-Goodger, C.; Bunting, S.; Xiang, Z.; Kohlhaas, S.; Das, P. P.; Miska, E. A.; Rodriguez, A.; Bradley, A.; Smith, K. G.; Rada, C.; Enright, A. J.; Toellner, K. M.; Maclennan, I. C.; Turner, M. microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells. Immunity, 2007, 27, 847-59.
    • Vigorito, E.; Perks, K. L.; Abreu-Goodger, C.; Bunting, S.; Xiang, Z.; Kohlhaas, S.; Das, P. P.; Miska, E. A.; Rodriguez, A.; Bradley, A.; Smith, K. G.; Rada, C.; Enright, A. J.; Toellner, K. M.; Maclennan, I. C.; Turner, M. microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells. Immunity, 2007, 27, 847-59.
  • 49
    • 36348973030 scopus 로고    scopus 로고
    • Derepression of microRNA-mediated protein translation inhibition by apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G) and its family members
    • Huang, J.; Liang, Z.; Yang, B.; Tian, H.; Ma, J.; Zhang, H. Derepression of microRNA-mediated protein translation inhibition by apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G) and its family members. J. Biol. Chem., 2007, 282, 33632-40.
    • (2007) J. Biol. Chem , vol.282 , pp. 33632-33640
    • Huang, J.1    Liang, Z.2    Yang, B.3    Tian, H.4    Ma, J.5    Zhang, H.6
  • 51
    • 33845275018 scopus 로고    scopus 로고
    • The isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts
    • Keene, J. D.; Komisarow, J. M.; Friedersdorf, M. B. RIP-Chip: The isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts. Nat. Protoc., 2006, 1, 302-7.
    • (2006) Nat. Protoc , vol.1 , pp. 302-307
    • Keene, J.D.1    Komisarow, J.M.2    Friedersdorf, M.3    RIP-Chip, B.4
  • 52
    • 47749154078 scopus 로고    scopus 로고
    • Systematic identification of mRNAs recruited to argonaute 2 by specific microRNAs and corresponding changes in transcript abundance
    • Hendrickson, D. G.; Hogan, D. J.; Herschlag, D.; Ferrell, J. E.; Brown, P. O. Systematic identification of mRNAs recruited to argonaute 2 by specific microRNAs and corresponding changes in transcript abundance. PLoS ONE, 2008, 3, e2126.
    • (2008) PLoS ONE , vol.3
    • Hendrickson, D.G.1    Hogan, D.J.2    Herschlag, D.3    Ferrell, J.E.4    Brown, P.O.5
  • 55
    • 25444520537 scopus 로고    scopus 로고
    • Cimmino, A.; Calin, G. A.; Fabbri, M.; Iorio, M. V.; Ferracin, M.; Shimizu, M.; Wojcik, S. E.; Aqeilan, R. I.; Zupo, S.; Dono, M.; Rassenti, L.; Alder, H.; Volinia, S.; Liu, C. G.; Kipps, T. J.; Negrini, M.; Croce, C. M. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc. Natl. Acad. Sci. USA, 2005, 102, 13944-9
    • Cimmino, A.; Calin, G. A.; Fabbri, M.; Iorio, M. V.; Ferracin, M.; Shimizu, M.; Wojcik, S. E.; Aqeilan, R. I.; Zupo, S.; Dono, M.; Rassenti, L.; Alder, H.; Volinia, S.; Liu, C. G.; Kipps, T. J.; Negrini, M.; Croce, C. M. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc. Natl. Acad. Sci. USA, 2005, 102, 13944-9
  • 63
    • 35748956868 scopus 로고    scopus 로고
    • Inamura, K.; Togashi, Y.; Nomura, K.; Ninomiya, H.; Hiramatsu, M.; Satoh, Y.; Okumura, S.; Nakagawa, K.; Ishikawa, Y. let-7 microRNA expression is reduced in bronchioloalveolar carcinoma, a non-invasive carcinoma, and is not correlated with prognosis. Lung Cancer, 2007, 58, 392-6.
    • Inamura, K.; Togashi, Y.; Nomura, K.; Ninomiya, H.; Hiramatsu, M.; Satoh, Y.; Okumura, S.; Nakagawa, K.; Ishikawa, Y. let-7 microRNA expression is reduced in bronchioloalveolar carcinoma, a non-invasive carcinoma, and is not correlated with prognosis. Lung Cancer, 2007, 58, 392-6.
  • 67
    • 33947431322 scopus 로고    scopus 로고
    • Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
    • Mayr, C.; Hemann, M. T.; Bartel, D. P. Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science, 2007, 315, 1576-9.
    • (2007) Science , vol.315 , pp. 1576-1579
    • Mayr, C.1    Hemann, M.T.2    Bartel, D.P.3
  • 72
    • 33644513730 scopus 로고    scopus 로고
    • Beyond PTEN mutations: The PI3K pathway as an integrator of multiple inputs during tumorigenesis
    • Cully, M.; You, H.; Levine, A. J.; Mak, T. W. Beyond PTEN mutations: The PI3K pathway as an integrator of multiple inputs during tumorigenesis. Nat. Rev. Cancer, 2006, 6, 184-92.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 184-192
    • Cully, M.1    You, H.2    Levine, A.J.3    Mak, T.W.4
  • 73
    • 43049128529 scopus 로고    scopus 로고
    • Tenets of PTEN tumor suppression
    • Salmena, L.; Carracedo, A.; Pandolfi, P. P. Tenets of PTEN tumor suppression. Cell, 2008, 133, 403-14.
    • (2008) Cell , vol.133 , pp. 403-414
    • Salmena, L.1    Carracedo, A.2    Pandolfi, P.P.3
  • 75
    • 4644257541 scopus 로고    scopus 로고
    • Rb family proteins differentially regulate distinct cell lineages during epithelial development
    • Wikenheiser-Brokamp, K. A. Rb family proteins differentially regulate distinct cell lineages during epithelial development. Development, 2004, 131, 4299-310.
    • (2004) Development , vol.131 , pp. 4299-4310
    • Wikenheiser-Brokamp, K.A.1
  • 78
    • 0742281300 scopus 로고    scopus 로고
    • E2F1 and c-Myc in cell growth and death
    • Matsumura, I.; Tanaka, H.; Kanakura, Y. E2F1 and c-Myc in cell growth and death. Cell Cycle, 2003, 2, 333-8.
    • (2003) Cell Cycle , vol.2 , pp. 333-338
    • Matsumura, I.1    Tanaka, H.2    Kanakura, Y.3
  • 80
    • 34047264639 scopus 로고    scopus 로고
    • Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors
    • Woods, K.; Thomson, J. M.; Hammond, S. M. Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J. Biol. Chem., 2007, 282, 2130-4.
    • (2007) J. Biol. Chem , vol.282 , pp. 2130-2134
    • Woods, K.1    Thomson, J.M.2    Hammond, S.M.3
  • 86
    • 0346727383 scopus 로고    scopus 로고
    • High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma
    • Metzler, M.; Wilda, M.; Busch, K.; Viehmann, S.; Borkhardt, A. High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma. Genes Chromosomes Cancer, 2004, 39, 167-9.
    • (2004) Genes Chromosomes Cancer , vol.39 , pp. 167-169
    • Metzler, M.1    Wilda, M.2    Busch, K.3    Viehmann, S.4    Borkhardt, A.5
  • 87
    • 38849198550 scopus 로고    scopus 로고
    • Coordinated expression of microRNA-155 and predicted target genes in diffuse large B-cell lymphoma
    • Rai, D.; Karanti, S.; Jung, I.; Dahia, P. L.; Aguiar, R. C. Coordinated expression of microRNA-155 and predicted target genes in diffuse large B-cell lymphoma. Cancer Genet. Cytogenet., 2008, 181, 8-15.
    • (2008) Cancer Genet. Cytogenet , vol.181 , pp. 8-15
    • Rai, D.1    Karanti, S.2    Jung, I.3    Dahia, P.L.4    Aguiar, R.C.5
  • 93
    • 38049030287 scopus 로고    scopus 로고
    • Modulation of miR-155 and miR-125b levels following lipopolysaccharide/ TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock
    • Tili, E.; Michaille, J. J.; Cimino, A.; Costinean, S.; Dumitru, C. D.; Adair, B.; Fabbri, M.; Alder, H.; Liu, C. G.; Calin, G. A.; Croce, C. M. Modulation of miR-155 and miR-125b levels following lipopolysaccharide/ TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J. Immunol., 2007, 179, 5082-9.
    • (2007) J. Immunol , vol.179 , pp. 5082-5089
    • Tili, E.1    Michaille, J.J.2    Cimino, A.3    Costinean, S.4    Dumitru, C.D.5    Adair, B.6    Fabbri, M.7    Alder, H.8    Liu, C.G.9    Calin, G.A.10    Croce, C.M.11
  • 94
    • 33745826614 scopus 로고    scopus 로고
    • MicroRNA-155 regulates human angiotensin II type 1 receptor expression in fibroblasts
    • Martin, M. M.; Lee, E. J.; Buckenberger, J. A.; Schmittgen, T. D.; Elton, T. S. MicroRNA-155 regulates human angiotensin II type 1 receptor expression in fibroblasts. J. Biol. Chem., 2006, 281, 18277-84.
    • (2006) J. Biol. Chem , vol.281 , pp. 18277-18284
    • Martin, M.M.1    Lee, E.J.2    Buckenberger, J.A.3    Schmittgen, T.D.4    Elton, T.S.5
  • 97
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan, J. A.; Krichevsky, A. M.; Kosik, K. S. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res., 2005, 65, 6029-33.
    • (2005) Cancer Res , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 98
    • 33750600178 scopus 로고    scopus 로고
    • MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior
    • Roldo, C.; Missiaglia, E.; Hagan, J. P.; Falconi, M.; Capelli, P.; Bersani, S.; Calin, G. A.; Volinia, S.; Liu, C. G.; Scarpa, A.; Croce, C. M. MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. J. Clin. Oncol., 2006, 24, 4677-84.
    • (2006) J. Clin. Oncol , vol.24 , pp. 4677-4684
    • Roldo, C.1    Missiaglia, E.2    Hagan, J.P.3    Falconi, M.4    Capelli, P.5    Bersani, S.6    Calin, G.A.7    Volinia, S.8    Liu, C.G.9    Scarpa, A.10    Croce, C.M.11
  • 101
    • 39049128249 scopus 로고    scopus 로고
    • Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer
    • Slaby, O.; Svoboda, M.; Fabian, P.; Smerdova, T.; Knoflickova, D.; Bednarikova, M.; Nenutil, R.; Vyzula, R. Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer. Oncology, 2007, 72, 397-402
    • (2007) Oncology , vol.72 , pp. 397-402
    • Slaby, O.1    Svoboda, M.2    Fabian, P.3    Smerdova, T.4    Knoflickova, D.5    Bednarikova, M.6    Nenutil, R.7    Vyzula, R.8
  • 104
    • 34247495591 scopus 로고    scopus 로고
    • Si, M. L.; Zhu, S.; Wu, H.; Lu, Z.; Wu, F.; Mo, Y. Y. miR-21-mediated tumor growth. Oncogene, 2007, 26, 2799-803.
    • Si, M. L.; Zhu, S.; Wu, H.; Lu, Z.; Wu, F.; Mo, Y. Y. miR-21-mediated tumor growth. Oncogene, 2007, 26, 2799-803.
  • 105
    • 34347266556 scopus 로고    scopus 로고
    • MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
    • Zhu, S.; Si, M. L.; Wu, H.; Mo, Y. Y. MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J. Biol. Chem., 2007, 282, 14328-36.
    • (2007) J. Biol. Chem , vol.282 , pp. 14328-14336
    • Zhu, S.1    Si, M.L.2    Wu, H.3    Mo, Y.Y.4
  • 106
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • Meng, F.; Henson, R.; Wehbe-Janek, H.; Ghoshal, K.; Jacob, S. T.; Patel, T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology, 2007, 133, 647-58.
    • (2007) Gastroenterology , vol.133 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3    Ghoshal, K.4    Jacob, S.T.5    Patel, T.6
  • 107
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
    • Asangani, I. A.; Rasheed, S. A.; Nikolova, D. A.; Leupold, J. H.; Colburn, N. H.; Post, S.; Allgayer, H. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene, 2008, 27, 2128-36.
    • (2008) Oncogene , vol.27 , pp. 2128-2136
    • Asangani, I.A.1    Rasheed, S.A.2    Nikolova, D.A.3    Leupold, J.H.4    Colburn, N.H.5    Post, S.6    Allgayer, H.7
  • 108
    • 38149042783 scopus 로고    scopus 로고
    • Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
    • Frankel, L. B.; Christoffersen, N. R.; Jacobsen, A.; Lindow, M.; Krogh, A.; Lund, A. H. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J. Biol. Chem., 2008, 283, 1026-33.
    • (2008) J. Biol. Chem , vol.283 , pp. 1026-1033
    • Frankel, L.B.1    Christoffersen, N.R.2    Jacobsen, A.3    Lindow, M.4    Krogh, A.5    Lund, A.H.6
  • 110
    • 40249092910 scopus 로고    scopus 로고
    • MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
    • Zhu, S.; Wu, H.; Wu, F.; Nie, D.; Sheng, S.; Mo, Y. Y. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res., 2008, 18, 350-9.
    • (2008) Cell Res , vol.18 , pp. 350-359
    • Zhu, S.1    Wu, H.2    Wu, F.3    Nie, D.4    Sheng, S.5    Mo, Y.Y.6
  • 112
    • 65649087385 scopus 로고    scopus 로고
    • Depletion of human microRNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation
    • Lee, Y. S.; Kim, H. K.; Chung, S.; Kim, K. S.; Dutta, A. Depletion of human microRNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation. J. Biol. Chem., 2005, 18, 18.
    • (2005) J. Biol. Chem , vol.18 , pp. 18
    • Lee, Y.S.1    Kim, H.K.2    Chung, S.3    Kim, K.S.4    Dutta, A.5
  • 118
    • 34548168073 scopus 로고    scopus 로고
    • Galardi, S.; Mercatelli, N.; Giorda, E.; Massalini, S.; Frajese, G. V.; Ciafre, S. A.; Farace, M. G. miR-221 and miR-222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1. J. Biol. Chem., 2007, 282, 23716-24.
    • Galardi, S.; Mercatelli, N.; Giorda, E.; Massalini, S.; Frajese, G. V.; Ciafre, S. A.; Farace, M. G. miR-221 and miR-222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1. J. Biol. Chem., 2007, 282, 23716-24.
  • 120
    • 37049010980 scopus 로고    scopus 로고
    • The guardian's little helper: MicroRNAs in the p53 tumor suppressor network
    • He, X.; He, L.; Hannon, G. J. The guardian's little helper: MicroRNAs in the p53 tumor suppressor network. Cancer Res., 2007, 67, 11099-101.
    • (2007) Cancer Res , vol.67 , pp. 11099-11101
    • He, X.1    He, L.2    Hannon, G.J.3
  • 121
    • 35748961986 scopus 로고    scopus 로고
    • p53 enters the microRNA world
    • Hermeking, H. p53 enters the microRNA world. Cancer Cell, 2007, 12, 414-8.
    • (2007) Cancer Cell , vol.12 , pp. 414-418
    • Hermeking, H.1
  • 124
    • 34548803950 scopus 로고    scopus 로고
    • MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth
    • Corney, D. C.; Flesken-Nikitin, A.; Godwin, A. K.; Wang, W.; Nikitin, A. Y. MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res., 2007, 67, 8433-8.
    • (2007) Cancer Res , vol.67 , pp. 8433-8438
    • Corney, D.C.1    Flesken-Nikitin, A.2    Godwin, A.K.3    Wang, W.4    Nikitin, A.Y.5
  • 127
    • 34250868124 scopus 로고    scopus 로고
    • Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: MiR-34a is a p53 target that induces apoptosis and G1-arrest
    • Tarasov, V.; Jung, P.; Verdoodt, B.; Lodygin, D.; Epanchintsev, A.; Menssen, A.; Meister, G.; Hermeking, H. Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: MiR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle, 2007, 6, 1586-93.
    • (2007) Cell Cycle , vol.6 , pp. 1586-1593
    • Tarasov, V.1    Jung, P.2    Verdoodt, B.3    Lodygin, D.4    Epanchintsev, A.5    Menssen, A.6    Meister, G.7    Hermeking, H.8
  • 128
    • 34848868157 scopus 로고    scopus 로고
    • Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells
    • Tazawa, H.; Tsuchiya, N.; Izumiya, M.; Nakagama, H. Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells. Proc. Natl. Acad. Sci. USA, 2007, 104, 15472-7.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 15472-15477
    • Tazawa, H.1    Tsuchiya, N.2    Izumiya, M.3    Nakagama, H.4
  • 133
    • 34247565615 scopus 로고    scopus 로고
    • The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
    • Lee, Y. S.; Dutta, A. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev., 2007, 21, 1025-30.
    • (2007) Genes Dev , vol.21 , pp. 1025-1030
    • Lee, Y.S.1    Dutta, A.2
  • 134
    • 33745700209 scopus 로고    scopus 로고
    • Sequence variations of microRNAs in human cancer: Alterations in predicted secondary structure do not affect processing
    • Diederichs, S.; Haber, D. A. Sequence variations of microRNAs in human cancer: Alterations in predicted secondary structure do not affect processing. Cancer Res., 2006, 66, 6097-104.
    • (2006) Cancer Res , vol.66 , pp. 6097-6104
    • Diederichs, S.1    Haber, D.A.2
  • 136
    • 46249092601 scopus 로고    scopus 로고
    • Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites
    • Sandberg, R.; Neilson, J. R.; Sarma, A.; Sharp, P. A.; Burge, C. B. Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites. Science, 2008, 320, 1643-7.
    • (2008) Science , vol.320 , pp. 1643-1647
    • Sandberg, R.1    Neilson, J.R.2    Sarma, A.3    Sharp, P.A.4    Burge, C.B.5
  • 138
    • 33847748913 scopus 로고    scopus 로고
    • The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function
    • Brueckner, B.; Stresemann, C.; Kuner, R.; Mund, C.; Musch, T.; Meister, M.; Sultmann, H.; Lyko, F. The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function. Cancer Res., 2007, 67, 1419-23.
    • (2007) Cancer Res , vol.67 , pp. 1419-1423
    • Brueckner, B.1    Stresemann, C.2    Kuner, R.3    Mund, C.4    Musch, T.5    Meister, M.6    Sultmann, H.7    Lyko, F.8
  • 139
  • 141
    • 40849108663 scopus 로고    scopus 로고
    • Selective blockade of microRNA processing by Lin28
    • Viswanathan, S. R.; Daley, G. Q.; Gregory, R. I. Selective blockade of microRNA processing by Lin28. Science, 2008, 320, 97-100.
    • (2008) Science , vol.320 , pp. 97-100
    • Viswanathan, S.R.1    Daley, G.Q.2    Gregory, R.I.3
  • 142
    • 52049124806 scopus 로고    scopus 로고
    • Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28
    • Piskounova, E.; Viswanathan, S. R.; Janas, M.; LaPierre, R. J.; Daley, G. Q.; Sliz, P.; Gregory, R. I. Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. J. Biol. Chem., 2008, 283, 21310-4.
    • (2008) J. Biol. Chem , vol.283 , pp. 21310-21314
    • Piskounova, E.1    Viswanathan, S.R.2    Janas, M.3    LaPierre, R.J.4    Daley, G.Q.5    Sliz, P.6    Gregory, R.I.7
  • 146
    • 34547480764 scopus 로고    scopus 로고
    • Oncogenic All1 fusion proteins target Drosha-mediated microRNA processing
    • Nakamura, T.; Canaani, E.; Croce, C. M. Oncogenic All1 fusion proteins target Drosha-mediated microRNA processing. Proc. Natl. Acad. Sci. USA, 2007, 104, 10980-5.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 10980-10985
    • Nakamura, T.1    Canaani, E.2    Croce, C.M.3
  • 147
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • Lee, Y.; Kim, M.; Han, J.; Yeom, K. H.; Lee, S.; Baek, S. H.; Kim, V. N. MicroRNA genes are transcribed by RNA polymerase II. EMBO J., 2004, 23, 4051-60.
    • (2004) EMBO J , vol.23 , pp. 4051-4060
    • Lee, Y.1    Kim, M.2    Han, J.3    Yeom, K.H.4    Lee, S.5    Baek, S.H.6    Kim, V.N.7
  • 148
    • 9344235449 scopus 로고
    • Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
    • Cai, X.; Hagedorn, C. H.; Cullen, B. R. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA, 2004, 10, 1957-66.
    • (1957) RNA , vol.2004 , pp. 10
    • Cai, X.1    Hagedorn, C.H.2    Cullen, B.R.3
  • 149
    • 6344281172 scopus 로고    scopus 로고
    • Identification of mammalian microRNA host genes and transcription units
    • Rodriguez, A.; Griffiths-Jones, S.; Ashurst, J. L.; Bradley, A. Identification of mammalian microRNA host genes and transcription units. Genome Res., 2004, 14, 1902-10.
    • (2010) Genome Res , vol.2004 , pp. 14
    • Rodriguez, A.1    Griffiths-Jones, S.2    Ashurst, J.L.3    Bradley, A.4
  • 151
    • 49749084410 scopus 로고    scopus 로고
    • Functional integration of microRNAs into oncogenic and tumor suppressor pathways
    • Lotterman, C. D.; Kent, O. A.; Mendell, J. T. Functional integration of microRNAs into oncogenic and tumor suppressor pathways. Cell Cycle, 2008, 7, 2493-9.
    • (2008) Cell Cycle , vol.7 , pp. 2493-2499
    • Lotterman, C.D.1    Kent, O.A.2    Mendell, J.T.3
  • 153
    • 42549092314 scopus 로고    scopus 로고
    • Giannakakis, A.; Sandaltzopoulos, R.; Greshock, J.; Liang, S.; Huang, J.; Hasegawa, K.; Li, C.; O'Brien-Jenkins, A.; Katsaros, D.; Weber, B. L.; Simon, C.; Coukos, G.; Zhang, L. miR-210 links hypoxia with cell cycle regulation and is deleted in human epithelial ovarian cancer. Cancer Biol. Ther., 2007, 7, 255-64.
    • Giannakakis, A.; Sandaltzopoulos, R.; Greshock, J.; Liang, S.; Huang, J.; Hasegawa, K.; Li, C.; O'Brien-Jenkins, A.; Katsaros, D.; Weber, B. L.; Simon, C.; Coukos, G.; Zhang, L. miR-210 links hypoxia with cell cycle regulation and is deleted in human epithelial ovarian cancer. Cancer Biol. Ther., 2007, 7, 255-64.
  • 159
  • 161
    • 38649094549 scopus 로고    scopus 로고
    • Disease control rate at 8 weeks predicts clinical benefit in advanced non-small-cell lung cancer: Results from Southwest Oncology Group randomized trials
    • Lara, P. N., Jr.; Redman, M. W.; Kelly, K.; Edelman, M. J.; Williamson, S. K.; Crowley, J. J.; Gandara, D. R. Disease control rate at 8 weeks predicts clinical benefit in advanced non-small-cell lung cancer: results from Southwest Oncology Group randomized trials. J. Clin. Oncol., 2008, 26, 463-7.
    • (2008) J. Clin. Oncol , vol.26 , pp. 463-467
    • Lara Jr., P.N.1    Redman, M.W.2    Kelly, K.3    Edelman, M.J.4    Williamson, S.K.5    Crowley, J.J.6    Gandara, D.R.7
  • 164
    • 38649140462 scopus 로고    scopus 로고
    • Advances in microRNAs: Implications for gene therapists
    • Marquez, R. T.; McCaffrey, A. P. Advances in microRNAs: Implications for gene therapists. Hum. Gene Ther., 2008, 19, 27-38
    • (2008) Hum. Gene Ther , vol.19 , pp. 27-38
    • Marquez, R.T.1    McCaffrey, A.P.2
  • 165
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: Competitive inhibitors of small RNAs in mammalian cells
    • Ebert, M. S.; Neilson, J. R.; Sharp, P. A. MicroRNA sponges: Competitive inhibitors of small RNAs in mammalian cells. Nat. Methods, 2007, 4, 721-6.
    • (2007) Nat. Methods , vol.4 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 166
    • 1242318826 scopus 로고    scopus 로고
    • Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing
    • Meister, G.; Landthaler, M.; Dorsett, Y.; Tuschl, T. Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing. RNA, 2004, 10, 544-50.
    • (2004) RNA , vol.10 , pp. 544-550
    • Meister, G.1    Landthaler, M.2    Dorsett, Y.3    Tuschl, T.4
  • 167
    • 39749166555 scopus 로고    scopus 로고
    • Randomized phase II Study of carboplatin and etoposide with or without the bcl-2 antisense oligonucleotide oblimersen for extensive-stage small-cell lung cancer: CALGB 30103
    • Rudin, C. M.; Salgia, R.; Wang, X.; Hodgson, L. D.; Masters, G. A.; Green, M.; Vokes, E. E. Randomized phase II Study of carboplatin and etoposide with or without the bcl-2 antisense oligonucleotide oblimersen for extensive-stage small-cell lung cancer: CALGB 30103. J. Clin. Oncol., 2008, 26, 870-6.
    • (2008) J. Clin. Oncol , vol.26 , pp. 870-876
    • Rudin, C.M.1    Salgia, R.2    Wang, X.3    Hodgson, L.D.4    Masters, G.A.5    Green, M.6    Vokes, E.E.7
  • 169
    • 33645075443 scopus 로고    scopus 로고
    • Esau, C.; Davis, S.; Murray, S. F.; Yu, X. X.; Pandey, S. K.; Pear, M.; Watts, L.; Booten, S. L.; Graham, M.; McKay, R.; Subramaniam, A.; Propp, S.; Lollo, B. A.; Freier, S.; Bennett, C. F.; Bhanot, S.; Monia, B. P. miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab., 2006, 3, 87-98
    • Esau, C.; Davis, S.; Murray, S. F.; Yu, X. X.; Pandey, S. K.; Pear, M.; Watts, L.; Booten, S. L.; Graham, M.; McKay, R.; Subramaniam, A.; Propp, S.; Lollo, B. A.; Freier, S.; Bennett, C. F.; Bhanot, S.; Monia, B. P. miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab., 2006, 3, 87-98
  • 172
    • 14644435784 scopus 로고    scopus 로고
    • Short interfering RNAs as a tool for cancer gene therapy
    • Izquierdo, M. Short interfering RNAs as a tool for cancer gene therapy. Cancer Gene Ther., 2005, 12, 217-27.
    • (2005) Cancer Gene Ther , vol.12 , pp. 217-227
    • Izquierdo, M.1
  • 176
    • 43049176170 scopus 로고    scopus 로고
    • Akinc, A.; Zumbuehl, A.; Goldberg, M.; Leshchiner, E. S.; Busini, V.; Hossain, N.; Bacallado, S. A.; Nguyen, D. N.; Fuller, J.; Alvarez, R.; Borodovsky, A.; Borland, T.; Constien, R.; de Fougerolles, A.; Dorkin, J. R.; Narayanannair Jayaprakash, K.; Jayaraman, M.; John, M.; Koteliansky, V.; Manoharan, M.; Nechev, L.; Qin, J.; Racie, T.; Raitcheva, D.; Rajeev, K. G.; Sah, D. W. Y.; Soutschek, J.; Toudjarska, I.; Vornlocher, H.-P.; Zimmermann, T. S.; Langer, R.; Anderson, D. G. A combinatorial library of lipid-like materials for delivery of RNAi therapeutics. Nat. Biotech., 2008, 26, 561-569
    • Akinc, A.; Zumbuehl, A.; Goldberg, M.; Leshchiner, E. S.; Busini, V.; Hossain, N.; Bacallado, S. A.; Nguyen, D. N.; Fuller, J.; Alvarez, R.; Borodovsky, A.; Borland, T.; Constien, R.; de Fougerolles, A.; Dorkin, J. R.; Narayanannair Jayaprakash, K.; Jayaraman, M.; John, M.; Koteliansky, V.; Manoharan, M.; Nechev, L.; Qin, J.; Racie, T.; Raitcheva, D.; Rajeev, K. G.; Sah, D. W. Y.; Soutschek, J.; Toudjarska, I.; Vornlocher, H.-P.; Zimmermann, T. S.; Langer, R.; Anderson, D. G. A combinatorial library of lipid-like materials for delivery of RNAi therapeutics. Nat. Biotech., 2008, 26, 561-569


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.