Colchicine: A novel positive allosteric modulator of the human 5-Hydroxytryptamine 3A receptor

Journal of Pharmacology and Experimental Therapeutics

Volumn 329, Issue 2, 2009, Pages 838-847

  De Oliveira Pierce, A N ^a   Zhang, R ^a,b   Machu, T K ^a,b  

^a UNIVERSITY OF NORTH TEXAS   (United States)

^b TEXAS TECH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLCHICINE; GRANISETRON; SEROTONIN; SEROTONIN 3A RECEPTOR; TRITIUM; HTR3A PROTEIN, HUMAN; HTR3A PROTEIN, MOUSE; ION CHANNEL; LIGAND; SEROTONIN RECEPTOR; SEROTONIN RECEPTOR AFFECTING AGENT;

ALLOSTERISM; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CHANNEL GATING; COLD; DEPOLYMERIZATION; DRUG BINDING; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; FEMALE; IC 50; INCUBATION TIME; LIGAND BINDING; MICROTUBULE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIOASSAY; TEMPERATURE; VOLTAGE CLAMP; XENOPUS LAEVIS; ANIMAL; BINDING COMPETITION; CELL MEMBRANE POTENTIAL; DOSE RESPONSE; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MOUSE; PATCH CLAMP; SPECIES DIFFERENCE;

ALLOSTERIC REGULATION; ANIMALS; BINDING, COMPETITIVE; COLCHICINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; ION CHANNELS; LIGANDS; MEMBRANE POTENTIALS; MICE; OOCYTES; PATCH-CLAMP TECHNIQUES; RADIOLIGAND ASSAY; RECEPTORS, SEROTONIN; SEROTONIN AGENTS; SPECIES SPECIFICITY; TRANSFECTION; XENOPUS LAEVIS;

EID: 65649123744     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.146522     Document Type: Article

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