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Volumn 502, Issue 1-2, 2004, Pages 31-40

Stable expression and characterisation of a human α7 nicotinic subunit chimera: A tool for functional high-throughput screening

Author keywords

7 subunit; 7 5 HT 3 chimera; (Human); HEK 293 cells; Nicotinic acetylcholine receptor

Indexed keywords

BUNGAROTOXIN RECEPTOR; COMPLEMENTARY DNA; NICOTINIC RECEPTOR; SEROTONIN 3 RECEPTOR; SEROTONIN RECEPTOR; UNCLASSIFIED DRUG;

EID: 4744369881     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.08.042     Document Type: Article
Times cited : (25)

References (50)
  • 2
    • 0033968763 scopus 로고    scopus 로고
    • Expression of a neuronal nicotinic acetylcholine receptor in insect and mammalian host cell systems
    • E.M. Aztiria, M.C. Sogayar, and F.J. Barrantes Expression of a neuronal nicotinic acetylcholine receptor in insect and mammalian host cell systems Neurochem. Res. 25 1 2000 171 180
    • (2000) Neurochem. Res. , vol.25 , Issue.1 , pp. 171-180
    • Aztiria, E.M.1    Sogayar, M.C.2    Barrantes, F.J.3
  • 3
    • 1642457187 scopus 로고    scopus 로고
    • Pharmacological properties of α9α10 nicotinic acetylcholine receptors revealed by heterologous expression of subunit chimeras
    • E.R. Baker, R. Zwart, E. Sher, and N.S. Millar Pharmacological properties of α9α10 nicotinic acetylcholine receptors revealed by heterologous expression of subunit chimeras Mol. Pharmacol. 65 2 2004 453 460
    • (2004) Mol. Pharmacol. , vol.65 , Issue.2 , pp. 453-460
    • Baker, E.R.1    Zwart, R.2    Sher, E.3    Millar, N.S.4
  • 4
    • 0030758521 scopus 로고    scopus 로고
    • Detection of functional nicotinic receptors blocked by α-bungarotoxin on PC12 cells and dependence of their expression on post-translational events
    • E.M. Blumenthal, W.G. Conroy, S.J. Romano, P.D. Kassner, and D. Berg Detection of functional nicotinic receptors blocked by α-bungarotoxin on PC12 cells and dependence of their expression on post-translational events J. Neurosci. 17 16 1997 6094 6104
    • (1997) J. Neurosci. , vol.17 , Issue.16 , pp. 6094-6104
    • Blumenthal, E.M.1    Conroy, W.G.2    Romano, S.J.3    Kassner, P.D.4    Berg, D.5
  • 5
    • 0030962495 scopus 로고    scopus 로고
    • Host cell-specific folding and assembly of the neuronal nicotinic acetylcholine receptor α7 subunit
    • S.T. Cooper, and N.S. Millar Host cell-specific folding and assembly of the neuronal nicotinic acetylcholine receptor α7 subunit J. Neurochem. 68 5 1997 2140 2151
    • (1997) J. Neurochem. , vol.68 , Issue.5 , pp. 2140-2151
    • Cooper, S.T.1    Millar, N.S.2
  • 6
    • 0031775951 scopus 로고    scopus 로고
    • Host cell-specific folding of the neuronal nicotinic receptor α8 ubunit
    • S.T. Cooper, and N.S. Millar Host cell-specific folding of the neuronal nicotinic receptor α8 ubunit J. Neurochem. 70 6 1998 2585 2593
    • (1998) J. Neurochem. , vol.70 , Issue.6 , pp. 2585-2593
    • Cooper, S.T.1    Millar, N.S.2
  • 7
    • 0033578873 scopus 로고    scopus 로고
    • Up-regulation of cell surface α4Iβ2 neuronal nicotinic receptors by lower temperature and expression of chimeric subunits
    • S.T. Cooper, P.C. Harkness, E.R. Baker, and N.S. Millar Up-regulation of cell surface α4Iβ2 neuronal nicotinic receptors by lower temperature and expression of chimeric subunits J. Biol. Chem. 274 38 1999 27145 27152
    • (1999) J. Biol. Chem. , vol.274 , Issue.38 , pp. 27145-27152
    • Cooper, S.T.1    Harkness, P.C.2    Baker, E.R.3    Millar, N.S.4
  • 8
    • 0029078817 scopus 로고
    • Identification of a new component of the agonist binding site of the nicotinic α7 homooligermeric receptor
    • P.J. Corringer, J.L. Galzi, J.L. Eisele, S. Bertrand, J.P. Changeaux, and D. Bertrand Identification of a new component of the agonist binding site of the nicotinic α7 homooligermeric receptor J. Biol. Chem. 270 20 1995 11749 11752
    • (1995) J. Biol. Chem. , vol.270 , Issue.20 , pp. 11749-11752
    • Corringer, P.J.1    Galzi, J.L.2    Eisele, J.L.3    Bertrand, S.4    Changeaux, J.P.5    Bertrand, D.6
  • 10
    • 0025605864 scopus 로고
    • A neuronal nicotinic acetylcholine receptor subunit α7 is developmentally regulated and forms homo-oligomeric channels blocked by α-Btx
    • S. Couturier, D. Bertrand, J.-M. Mattler, M.-C. Hernandez, S. Bertrand, N. Millar, S. Valera, T. Barkas, and M. Ballivet A neuronal nicotinic acetylcholine receptor subunit α7 is developmentally regulated and forms homo-oligomeric channels blocked by α-Btx Neuron 5 1990 847 856
    • (1990) Neuron , vol.5 , pp. 847-856
    • Couturier, S.1    Bertrand, D.2    Mattler, J.-M.3    Hernandez, M.-C.4    Bertrand, S.5    Millar, N.6    Valera, S.7    Barkas, T.8    Ballivet, M.9
  • 11
    • 0034607693 scopus 로고    scopus 로고
    • Amino acid determinants of alpha 7 nicotinic receptor surface expression
    • K.T. Dineley, and J.W. Patrick Amino acid determinants of alpha 7 nicotinic receptor surface expression J. Biol. Chem. 275 2000 13974 13985
    • (2000) J. Biol. Chem. , vol.275 , pp. 13974-13985
    • Dineley, K.T.1    Patrick, J.W.2
  • 12
    • 0034000995 scopus 로고    scopus 로고
    • Neuronal α-bungarotoxin receptors are α7 subunit homomers
    • R.C. Drisdel, and W.N. Green Neuronal α-bungarotoxin receptors are α7 subunit homomers J. Neurosci. 20 1 2000 133 139
    • (2000) J. Neurosci. , vol.20 , Issue.1 , pp. 133-139
    • Drisdel, R.C.1    Green, W.N.2
  • 13
    • 4744361102 scopus 로고    scopus 로고
    • The role of palmitoylation in neuronal nicotinic acetylcholine alpha 7 subunit expression
    • R.C. Drisdel, and W.N. Green The role of palmitoylation in neuronal nicotinic acetylcholine alpha 7 subunit expression Soc.-Abstr. Neurosci. 2002 (Abstract No. 537.6)
    • (2002) Soc.-Abstr. Neurosci.
    • Drisdel, R.C.1    Green, W.N.2
  • 14
    • 0027772476 scopus 로고
    • Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities
    • J.-L. Eisele, S. Bertrand, J.-L. Galzi, A. Devillers-Thlery, J.-P. Changeux, and D. Bertrand Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities Nature 366 1993 479 483
    • (1993) Nature , vol.366 , pp. 479-483
    • Eisele, J.-L.1    Bertrand, S.2    Galzi, J.-L.3    Devillers-Thlery, A.4    Changeux, J.-P.5    Bertrand, D.6
  • 15
    • 0028171296 scopus 로고
    • Alpha 9: An acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells
    • A.B. Elgoyhen, D.S. Johnson, J. Boulter, D.E. Vetter, and S. Heinemann Alpha 9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells Cell 79 1994 705 715
    • (1994) Cell , vol.79 , pp. 705-715
    • Elgoyhen, A.B.1    Johnson, D.S.2    Boulter, J.3    Vetter, D.E.4    Heinemann, S.5
  • 16
    • 0030226911 scopus 로고    scopus 로고
    • Comparative structure of human neuronal α2-α7 and α2-α4 nicotinic acetylcholine receptor subunits and functional expression of the α2, α3, α4, α7, α2, and α4 subunits
    • K.J. Elliot, S.B. Ellis, K.J. Berckhan, A. Urrutia, L.E. Chavez-Noriega, E.C. Johnson, G. Velicelebi, and M.M. Harpold Comparative structure of human neuronal α2-α7 and α2-α4 nicotinic acetylcholine receptor subunits and functional expression of the α2, α3, α4, α7, α2, and α4 subunits J. Mol. Neurosci. 7 1996 217 228
    • (1996) J. Mol. Neurosci. , vol.7 , pp. 217-228
    • Elliot, K.J.1    Ellis, S.B.2    Berckhan, K.J.3    Urrutia, A.4    Chavez-Noriega, L.E.5    Johnson, E.C.6    Velicelebi, G.7    Harpold, M.M.8
  • 18
    • 0028177088 scopus 로고
    • Homomers of alpha8 and alpha7 subunits of nicotinic receptors exhibit similar channels but contrasting binding site properties
    • V. Gerzanich, R. Anand, and J. Lindstrom Homomers of alpha8 and alpha7 subunits of nicotinic receptors exhibit similar channels but contrasting binding site properties Mol. Pharmacol. 45 1994 212 220
    • (1994) Mol. Pharmacol. , vol.45 , pp. 212-220
    • Gerzanich, V.1    Anand, R.2    Lindstrom, J.3
  • 20
    • 0002342182 scopus 로고    scopus 로고
    • 5-Hydroxyindole potentiates the nicotinic acetylcholine receptor alpha 7 subtype
    • D.A. Gurley, E.W. Harris, C. Li, E.C. Johnson, and T.H. Lanthorn 5-Hydroxyindole potentiates the nicotinic acetylcholine receptor alpha 7 subtype Abstr. - Soc. Neurosci. 26 1-2 2000 (Abstract No. 716.15)
    • (2000) Abstr. - Soc. Neurosci. , vol.26 , Issue.12
    • Gurley, D.A.1    Harris, E.W.2    Li, C.3    Johnson, E.C.4    Lanthorn, T.H.5
  • 21
    • 0029593370 scopus 로고
    • Towards a structural basis for the function of nicotinic acetylcholine receptors and their cousins
    • A. Karlin, and M.H. Akabas Towards a structural basis for the function of nicotinic acetylcholine receptors and their cousins Neuron 15 1995 1231 1244
    • (1995) Neuron , vol.15 , pp. 1231-1244
    • Karlin, A.1    Akabas, M.H.2
  • 22
    • 0030729249 scopus 로고    scopus 로고
    • Differences in the fate of neuronal acetylcholine receptor protein expressed in neurons and stably transfected cells
    • P.D. Kassner, and D.K. Berg Differences in the fate of neuronal acetylcholine receptor protein expressed in neurons and stably transfected cells J. Neurobiol. 33 1997 968 982
    • (1997) J. Neurobiol. , vol.33 , pp. 968-982
    • Kassner, P.D.1    Berg, D.K.2
  • 23
    • 0035947642 scopus 로고    scopus 로고
    • Adjacent basic amino acid residues recognised by the COP I complex and ubiquitination govern endoplasmic reticulum to cell surface trafficking of the nicotinic acetylcholine receptor α-subunit
    • S.H. Keller, J. Lindstrom, M. Ellisman, and P. Taylor Adjacent basic amino acid residues recognised by the COP I complex and ubiquitination govern endoplasmic reticulum to cell surface trafficking of the nicotinic acetylcholine receptor α-subunit J. Biol. Chem. 276 21 2001 18384 18391
    • (2001) J. Biol. Chem. , vol.276 , Issue.21 , pp. 18384-18391
    • Keller, S.H.1    Lindstrom, J.2    Ellisman, M.3    Taylor, P.4
  • 24
    • 0033626286 scopus 로고    scopus 로고
    • The brain alpha7 nicotinic receptor may be an important therapeutic target for the treatment of Alzheimer's disease: Studies with DMXBA (GTS-21)
    • W.R. Kem The brain alpha7 nicotinic receptor may be an important therapeutic target for the treatment of Alzheimer's disease: studies with DMXBA (GTS-21) Behav. Brain Res. 113 2000 169 181
    • (2000) Behav. Brain Res. , vol.113 , pp. 169-181
    • Kem, W.R.1
  • 25
    • 0027530776 scopus 로고
    • 5-Hydroxyindole slows desensitization of 5-HT3 receptor-mediated ion current in N1E-115 neuroblastoma cells
    • A.R. Kooyman, J.A. Van Hooft, and H.P.M. Vijverberg 5-Hydroxyindole slows desensitization of 5-HT3 receptor-mediated ion current in N1E-115 neuroblastoma cells Br. J. Pharmacol. 108 1993 287 289
    • (1993) Br. J. Pharmacol. , vol.108 , pp. 287-289
    • Kooyman, A.R.1    Van Hooft, J.A.2    Vijverberg, H.P.M.3
  • 26
    • 0033626554 scopus 로고    scopus 로고
    • Human α6 AchR subtypes: Subunit composition, assembly, and pharmacological responses
    • A. Kuryatov, F. Olale, J. Cooper, C. Choi, and J. Lindstrom Human α6 AchR subtypes: subunit composition, assembly, and pharmacological responses Neuropharmacology 39 2000 2570 2590
    • (2000) Neuropharmacology , vol.39 , pp. 2570-2590
    • Kuryatov, A.1    Olale, F.2    Cooper, J.3    Choi, C.4    Lindstrom, J.5
  • 28
    • 0000110445 scopus 로고    scopus 로고
    • The structures of neuronal nicotinic receptors
    • F. Clementi D. Fornasari C. Gotti Springer-Verlag New York
    • J. Lindstrom The structures of neuronal nicotinic receptors F. Clementi D. Fornasari C. Gotti Handbook of Experimental Pharmacology Neuronal Nicotinic Receptors vol. 144 2000 Springer-Verlag New York 101 162
    • (2000) Handbook of Experimental Pharmacology. Neuronal Nicotinic Receptors , vol.144 , pp. 101-162
    • Lindstrom, J.1
  • 29
    • 0035836747 scopus 로고    scopus 로고
    • β-Amyloid peptide blocks the response of α7-containing nicotinic receptors on hippocampal neurons
    • Q.S. Lui, H. Kawai, and D.K. Berg β-Amyloid peptide blocks the response of α7-containing nicotinic receptors on hippocampal neurons Proc. Natl. Acad. Sci. 98 8 2001 4734 4739
    • (2001) Proc. Natl. Acad. Sci. , vol.98 , Issue.8 , pp. 4734-4739
    • Lui, Q.S.1    Kawai, H.2    Berg, D.K.3
  • 31
    • 0028965629 scopus 로고
    • Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurones
    • D.S. McGehee, and L.W. Role Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurones Annu. Rev. Physiol. 57 1995 521 546
    • (1995) Annu. Rev. Physiol. , vol.57 , pp. 521-546
    • McGehee, D.S.1    Role, L.W.2
  • 32
    • 0042067949 scopus 로고    scopus 로고
    • Assembly and subunit diversity of nicotinic acetylcholine receptors
    • N.S. Millar Assembly and subunit diversity of nicotinic acetylcholine receptors Biochem. Soc. Trans. 31 2003 869 874
    • (2003) Biochem. Soc. Trans. , vol.31 , pp. 869-874
    • Millar, N.S.1
  • 33
    • 0033577455 scopus 로고    scopus 로고
    • Inducible, heterologous expression of human α7-nicotinic acetylcholine receptors in a native nicotinic receptor-null human clonal line
    • J.H. Peng, L. Lucero, J. Fryer, J. Herl, S.S. Leonard, and R.J. Lukas Inducible, heterologous expression of human α7-nicotinic acetylcholine receptors in a native nicotinic receptor-null human clonal line Brain Res. 825 1999 172 179
    • (1999) Brain Res. , vol.825 , pp. 172-179
    • Peng, J.H.1    Lucero, L.2    Fryer, J.3    Herl, J.4    Leonard, S.S.5    Lukas, R.J.6
  • 34
    • 0027996141 scopus 로고
    • Functional expression of nicotinic acetylcholine receptors containing rat α7 subunits in human Sh-SY5Y neuroblastoma cells
    • E. Puchacz, B. Buisson, D. Bertrand, and R.J. Lukas Functional expression of nicotinic acetylcholine receptors containing rat α7 subunits in human Sh-SY5Y neuroblastoma cells FEBS Lett. 354 1994 155 159
    • (1994) FEBS Lett. , vol.354 , pp. 155-159
    • Puchacz, E.1    Buisson, B.2    Bertrand, D.3    Lukas, R.J.4
  • 35
    • 0030013768 scopus 로고    scopus 로고
    • Similarity between rat brain nicotinic α-bungarotoxin receptors and stably expressed α-bungarotoxin binding sites
    • M. Quik, J. Choremis, J. Komourain, R.J. Lukas, and E. Puchacz Similarity between rat brain nicotinic α-bungarotoxin receptors and stably expressed α-bungarotoxin binding sites J. Neurochem. 67 1996 145 154
    • (1996) J. Neurochem. , vol.67 , pp. 145-154
    • Quik, M.1    Choremis, J.2    Komourain, J.3    Lukas, R.J.4    Puchacz, E.5
  • 39
    • 0033549478 scopus 로고    scopus 로고
    • α-Bungarotoxin receptors contain α7 subunits in two different disulphide-bonded conformations
    • S. Rakhilin, R.C. Drisdel, D. Sagher, D.S. McGehee, Y. Vallejo, and W.N. Green α-Bungarotoxin receptors contain α7 subunits in two different disulphide-bonded conformations J. Cell Biol. 146 1 1999 203 217
    • (1999) J. Cell Biol. , vol.146 , Issue.1 , pp. 203-217
    • Rakhilin, S.1    Drisdel, R.C.2    Sagher, D.3    McGehee, D.S.4    Vallejo, Y.5    Green, W.N.6
  • 41
    • 19644375284 scopus 로고    scopus 로고
    • FLIPR: A new instrument for accurate, high throughout optical screening
    • K.S. Schroeder, and B.D. Neagle FLIPR: A new instrument for accurate, high throughout optical screening J. Biomol. Screen. 1 1996 75 80
    • (1996) J. Biomol. Screen. , vol.1 , pp. 75-80
    • Schroeder, K.S.1    Neagle, B.D.2
  • 42
    • 0037998063 scopus 로고    scopus 로고
    • Regulation by cycloheximide and lowered temperature of cell-surface α7-nicotinic acetylcholine receptor expression on transfected SH-EP1 cells
    • K.M. Schroeder, J. Wu, L. Zhao, and R.J. Lukas Regulation by cycloheximide and lowered temperature of cell-surface α7-nicotinic acetylcholine receptor expression on transfected SH-EP1 cells J. Neurochem. 85 2003 581 591
    • (2003) J. Neurochem. , vol.85 , pp. 581-591
    • Schroeder, K.M.1    Wu, J.2    Zhao, L.3    Lukas, R.J.4
  • 44
    • 0035470834 scopus 로고    scopus 로고
    • Intragastric DMXB-A, an α7 nicotinic agonist, improves deficient sensory inhibition in DBA/2 mice
    • J.K. Simosky, K.E. Stevens, W.R. Kem, and R. Freedman Intragastric DMXB-A, an α7 nicotinic agonist, improves deficient sensory inhibition in DBA/2 mice Biol. Psychiatry 50 2001 493 500
    • (2001) Biol. Psychiatry , vol.50 , pp. 493-500
    • Simosky, J.K.1    Stevens, K.E.2    Kem, W.R.3    Freedman, R.4
  • 45
    • 0033964182 scopus 로고    scopus 로고
    • Multistep expression and assembly of neuronal nicotinic receptors is both host-cell and receptor-subtype dependent
    • W. Sweileh, K. Wenberg, J. Xu, J. Forsayeth, S. Hardy, and R.H. Loring Multistep expression and assembly of neuronal nicotinic receptors is both host-cell and receptor-subtype dependent Brain Res. Mol. Brain Res. 75 2000 293 302
    • (2000) Brain Res. Mol. Brain Res. , vol.75 , pp. 293-302
    • Sweileh, W.1    Wenberg, K.2    Xu, J.3    Forsayeth, J.4    Hardy, S.5    Loring, R.H.6
  • 46
    • 0034658601 scopus 로고    scopus 로고
    • Receptor targeting and heterogeneity at interneuronal nicotinic cholinergic synapses in vivo
    • M.K. Temburni, R.C. Blitzbau, and M.H. Jacob Receptor targeting and heterogeneity at interneuronal nicotinic cholinergic synapses in vivo J. Physiol. 252 1 2000 21 29
    • (2000) J. Physiol. , vol.252 , Issue.1 , pp. 21-29
    • Temburni, M.K.1    Blitzbau, R.C.2    Jacob, M.H.3
  • 48
    • 0037066903 scopus 로고    scopus 로고
    • Pharmacological properties of rat α7 nicotinic receptors expressed in native and recombinant cell systems
    • C. Virginio, A. Giacometti, L. Aldegheri, J.M. Rimland, and G.C. Terstappen Pharmacological properties of rat α7 nicotinic receptors expressed in native and recombinant cell systems Eur. J. Pharmacol. 445 3 2002 153 161
    • (2002) Eur. J. Pharmacol. , vol.445 , Issue.3 , pp. 153-161
    • Virginio, C.1    Giacometti, A.2    Aldegheri, L.3    Rimland, J.M.4    Terstappen, G.C.5
  • 49
    • 0032198234 scopus 로고    scopus 로고
    • The long internal loop of the α3 subunit targets nAChRs to subdomains within individual synapses on neurons in vivo
    • B.M. Williams, M.K. Temburni, M.S. Levey, S. Bertrand, D. Bertrand, and M.H. Jacob The long internal loop of the α3 subunit targets nAChRs to subdomains within individual synapses on neurons in vivo Nat. Neurosci. 1 7 1998 557 562
    • (1998) Nat. Neurosci. , vol.1 , Issue.7 , pp. 557-562
    • Williams, B.M.1    Temburni, M.K.2    Levey, M.S.3    Bertrand, S.4    Bertrand, D.5    Jacob, M.H.6
  • 50
    • 0036711318 scopus 로고    scopus 로고
    • 5-Hydroxyindole potentiates human α7 nicotinic receptor-mediated responses and enhances acetylcholine-induced glutamate release in cerebellar slices
    • R. Zwart, G. DeFilippi, L.M. Broad, G.I. McPhie, K.H. Pearson, T. Baldwinson, and E. Sher 5-Hydroxyindole potentiates human α7 nicotinic receptor-mediated responses and enhances acetylcholine-induced glutamate release in cerebellar slices Neuropharmacology 43 2002 374 384
    • (2002) Neuropharmacology , vol.43 , pp. 374-384
    • Zwart, R.1    Defilippi, G.2    Broad, L.M.3    McPhie, G.I.4    Pearson, K.H.5    Baldwinson, T.6    Sher, E.7


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