Allosteric potentiation of the 5-HT3 receptor-mediated ion current in N1E-115 neuroblastoma cells by 5-hydroxyindole and analogues

Neuropharmacology

Volumn 36, Issue 4-5, 1997, Pages 649-653

  Van Hooft, J A ^a   Van Der Haar, E ^a   Vijverberg, H P M ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

5 HT3 receptor; 5 Hydroxyindole; Allosteric modulation; N1E 115 neuroblastoma; Potentiation; Single channel patch clamp; Whole cell voltage clamp

Indexed keywords

5 AMINOINDOLE; 5 HYDROXYINDOLE; 5 HYDROXYINDOLE DERIVATIVE; CATECHOL; INDOLE; ION CHANNEL; SEROTONIN; SEROTONIN 3 RECEPTOR; UNCLASSIFIED DRUG;

AGONIST; ALLOSTERISM; ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DOSE TIME EFFECT RELATION; DRUG POTENTIATION; ION CURRENT; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RECEPTOR AFFINITY; VOLTAGE CLAMP;

ANIMALS; BRAIN NEOPLASMS; CATECHOLS; INDOLES; ION CHANNELS; MEMBRANE POTENTIALS; MICE; NEUROBLASTOMA; PATCH-CLAMP TECHNIQUES; RECEPTORS, SEROTONIN; TUMOR CELLS, CULTURED;

EID: 0031004621     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(97)00045-2     Document Type: Article

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