Positive allosteric modulation of the α7 nicotinic acetylcholine receptor: Ligand interactions with distinct binding sites and evidence for a prominent role of the M2-M3 segment

Molecular Pharmacology

Volumn 74, Issue 5, 2008, Pages 1407-1416

  Bertrand, Daniel ^a   Bertrand, Sonia ^a   Cassar, Steven ^b   Gubbins, Earl ^b   Li, Jinhe ^b   Gopalakrishnan, M ^b  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 CHLORO 2 HYDROXYPHENYL) 3 (2 CHLORO 5 TRIFLUOROMETHYLPHENYL)UREA; 1 (5 CHLORO 2,4 DIMETHOXYPHENYL) 3 (5 METHYLISOXAZOL 3 YL)UREA; BUNGAROTOXIN RECEPTOR; NS 1738; PNU 120596; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BINDING SITE; DRUG RECEPTOR BINDING; DRUG STRUCTURE; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; DNA PRIMERS; FEMALE; LIGANDS; MOLECULAR SEQUENCE DATA; RECEPTORS, NICOTINIC; XENOPUS LAEVIS;

EID: 54349102284     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.107.042820     Document Type: Article

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