Immunotargeting of catalase to the pulmonary endothelium alleviates oxidative stress and reduces acute lung transplantation injury

Nature Biotechnology

Volumn 21, Issue 4, 2003, Pages 392-398

  Kozower, Benjamin D ^a   Christofidou Solomidou, Melpo ^b   Sweitzer, Thomas D ^b   Muro, Silvia ^b   Buerk, Donald G ^b   Solomides, Charalambos C ^c   Albelda, Steven M ^b   Patterson, G Alexander ^a   Muzykantov, Vladimir R ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c TEMPLE UNIVERSITY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANTS; CELLS; ENZYMES; TRANSPLANTATION (SURGICAL);

LUNG TRANSPLANTATION;

BIOTECHNOLOGY;

ANTIBODY CONJUGATE; ANTIOXIDANT; CATALASE; CELL ADHESION MOLECULE; CELL ADHESION MOLECULE 1; ENZYME; UNCLASSIFIED DRUG;

ACUTE DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; COLD INJURY; CONTROLLED STUDY; CRYOPRESERVATION; DONOR; DRUG ACTIVITY; DRUG DELIVERY SYSTEM; DRUG TARGETING; EXPERIMENTAL MODEL; IMMUNE SYSTEM; ISCHEMIA; LUNG BLOOD VESSEL; LUNG ENDOTHELIUM; LUNG INJURY; LUNG TRANSPLANTATION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; VALIDATION PROCESS;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD31; ANTIOXIDANTS; CATALASE; CELLS, CULTURED; DRUG DELIVERY SYSTEMS; ENDOTHELIUM, VASCULAR; HUMANS; IMMUNOTHERAPY; LUNG; LUNG TRANSPLANTATION; OXIDATIVE STRESS; RATS; RATS, INBRED F344; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY;

ANIMALIA;

EID: 12244298160     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt806     Document Type: Article

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