Synthesis and characterization of long chain alkyl acyl carnitine esters. Potentially biodegradable cationic lipids for use in gene delivery

Journal of Medicinal Chemistry

Volumn 41, Issue 13, 1998, Pages 2207-2215

  Wang, Jinkang ^a   Guo, Xin ^a   Xu, Yuhong ^a   Barron, Lee ^a   Szoka Jr , Francis C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARNITINE DERIVATIVE; CHOLESTEROL; DIOLEOYLPHOSPHATIDYLCHOLINE; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; OLEOYL OLEOYL CARNITINE ESTER; UNCLASSIFIED DRUG;

ARTICLE; BIODEGRADATION; COMPLEX FORMATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG SYNTHESIS; FATTY ACID METABOLISM; GENE TARGETING; GENE THERAPY; GENE TRANSFER; NONHUMAN; PROTEIN DNA INTERACTION;

ANIMALS; BETA-GALACTOSIDASE; BIODEGRADATION, ENVIRONMENTAL; CALORIMETRY, DIFFERENTIAL SCANNING; CARNITINE; CELL LINE; CELL SURVIVAL; DNA; DRUG CARRIERS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE THERAPY; INJECTIONS, INTRAVENOUS; LIPOSOMES; LIVER; LUCIFERASES; LUNG; MICE; MICE, INBRED ICR; MYOCARDIUM; PLASMIDS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 0032543524     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950802i     Document Type: Article

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