Novel structural insights into class I and II histone deacetylases

Current Topics in Medicinal Chemistry

Volumn 9, Issue 3, 2009, Pages 235-240

  Ficner, Ralf ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Crystal structure; Drug design; HDAC; Inhibitor

Indexed keywords

ASPARTIC ACID; HISTONE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE 4; HISTONE DEACETYLASE 5; HISTONE DEACETYLASE 7; HISTONE DEACETYLASE 8; HISTONE DEACETYLASE INHIBITOR; LYSINE; PHENYLALANINE; TYROSINE; ZINC ION;

APOPTOSIS; CANCER CELL CULTURE; CELL CYCLE REGULATION; CELL DIFFERENTIATION; CELL SURVIVAL; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DEACETYLATION; DRUG DESIGN; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME STRUCTURE; ENZYME SUBSTRATE; GROWTH INHIBITION; HUMAN; MOLECULAR RECOGNITION; PROTEIN FAMILY; REVIEW;

CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HISTONE DEACETYLASES; HUMANS; PROTEIN CONFORMATION; REPRESSOR PROTEINS;

EID: 65449166411     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/156802609788085304     Document Type: Review

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