Programmed cell death and cancer

Postgraduate Medical Journal

Volumn 85, Issue 1001, 2009, Pages 134-140

  Sun, Y ^a,b   Peng, Z L ^a  

^a SICHUAN UNIVERSITY   (China)

^b FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ANTINEOPLASTIC AGENT; BECLIN 1; BORTEZOMIB; CASPASE; CASPASE 3; CASPASE 6; CASPASE 8; CASPASE 9; CYCLOPHOSPHAMIDE; FLUDARABINE; LENALIDOMIDE; OBLIMERSEN; PROTEASOME INHIBITOR; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X; PROTEIN P53; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; AUTOPHAGY; CANCER CELL; CANCER THERAPY; CELL DEATH; CHRONIC LYMPHATIC LEUKEMIA; HUMAN; MULTIPLE MYELOMA; NONHUMAN; REVIEW;

ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; HUMANS; NECROSIS; NEOPLASMS;

EID: 65349191918     PISSN: 00325473     EISSN: 14690756     Source Type: Journal    
DOI: 10.1136/pgmj.2008.072629     Document Type: Review

References (83)

1. Gozuacik D, Kimchi A. Autophagy and cell death. Curr Top Dev Biol 2007:78:217-15.
2. Clarke PGH. Apoptosis: from morphological types of cell death to interacting pathways. Trends harmacol Sci 2002:23:308-9 (author reply 310)
3. Hengartner MO. The biochemistry of apoptosis. Nature 2000:407:770-6.
4. Klionsky DJ. The molecular machinery of autophagy: Unanswered questions. J Cell Sci 2005:118:7-18.
5. Mashima T, Tsuruo T. Defects of the apoptotic pathway as therapeutic target against cancer. Drug Resist Updat 2005:8:339- 43.
6. Boujrad H, Gubkina O, Robert N, et al. AIF mediated programmed necrosis: A highly regulated way to die. Cell Cycle 2007:6:2611-8.
7. Edinger AL, Thompson CB. Death by design: apoptosis, necrosis and autophagy. Curr Opin Cell Biol 2004:16:663-9.
8. Green DR, Reed JC. Mitochondria and apoptosis. Science 1998:281:1309-12.
9. Igney FH, Krammer PH. Death and anti-death: tumour resistance to apoptosis. Nat Rev Cancer 2002:2:277-88.
10. Iannolo G, Conticello C, Memeo L, et al. Apoptosis in normal and cancer stem cells. Crit Rev Oncol Hemet 2008:66:42-51.
11. Danial NN, Korsmeyer SJ. Cell death: critical control points. Cell 2004:116:205-19.
12. Heath-Engel HM, Shore GC. Mitochondrial membrane dynamic, cristae remodeling and apoptosis. Biochim Biophys Acta 2006:1763:549-60.
13. Kim R, Emi M, Tanabe K, et al. Regulation and interplay of apoptotic and non- apoptotic cell death. J Pathol 2006:208:319-26.
14. Li HL, Zhu H, Xu CJ, et al. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998:94:491-501.
15. Desagher S, 0sen-Sand A, Nichols A, et al. Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis, J Cell Biol 1999:144:891-901.
16. Martinvalet D, Zhu P, Lieberman J. Granzyme A induces caspase-independent mitochondrial damage, a required first step for apoptosis. Immunity 2005:22:355-70.
17. Maiuri MC, Zalckvar E, Kimchi A, et al. Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 2007:8:741-52.
18. Reggiori F, Klionsky DJ. Autophagosomes: biogenesis from scratch? Curr Opin Cell Biol 2005:17:415-22.
19. Levine B, Yuan J. Autophagy in cell death: an innocent convict? J Clin Invest 2005:115:2679-88.
20. Sun Y, Peng ZL. Autophagy, beclin1, and their relation with oncogenesis. Labmedicine 2008:39:287-90.
21. Luthi AU, Martin SJ. The CASBAH: a searchable database of caspase substrates. Cell Death Differ 2007:14:641-50.
22. Tsujimoto Y, Shimizu S. Another way to die: autophagic programmed cell death. Cell Death Differ 2005:12(Suppl 2):1528-34.
23. Shimizu S, Kanaseki T, Mizushima N, et al. Role of Bcl-2 family proteins in a non- apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol 2004:6:1221-8.
24. Yu L, Alva A, Su H, et al. Regulation of an ATG7-beclin1 program of autophagic cell death by caspase-8. Science 2004:304:1500-2.
25. Cuervo AM. Autophagy: in sickness and in health. Trends Cell Biol 2004:14:70-7.
26. Codogno P, Meijer AJ. Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ 2005:12(Suppl. 2):1509-18.
27. Golstein P, Kroemer G. Cell death by necrosis: towards a molecular definition. Trends Biochem Sci 2007:32:37-43.
28. Lotze MT, Tracey KJ. High-mobility group box 1 protein (HMGB): Nuclear weapon in the immune arsenal. Nat Rev Immunol 2005:5:331-42.
29. Zeh HJ, Lotze MT. Addicted to death - Invasive cancer and the immune response to unscheduled cell death. J Immunother 2005:28:1-9.
30. Bras M, Yuste VJ, Roue G, et al. Drp1 mediates caspase- independent type III cell death in normal and leukemic cells. Mol Cell Biol 2007:27:7073-88.
31. Moubarak RS, Yuste VJ, Artus C, et al. Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis. Mol Cell Biol 2007:27:4844-62.
32. Vanden Berghe T, Van Loo G, Saelens X, et al. Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD. J Biol Chem 2004:279:7925-33.
33. Okada H, Mak TW. Pathways of apoptotic and non-apoptotic death in tumour cells. Nat Rev Cancer 2004:4:592-603.
34. Bykov VJ, Issaeva N, Selivanova G, et al. Mutant p53-dependent growth suppression distinguishes PRIMA-1 from known anticancer drugs: a statistical analysis of information in the National Cancer Institute database. Carcinogenesis 2002:23:2011-18.
35. Flores ER, Sengupta S, Miller JB, et al. Tumor predisposition in mice mutant for p63 and p73: Evidence for broader tumor suppressor functions for the p53 family. Cancer Cell 2005:7:363- 73.
36. Zaika AI, Slade N, Erster SH, et al. ?Np73, a dominant-negative inhibitor of wild-type p53 and TAp73, is upregulated in human tumors. J Exp Med 2002:196:765-80.
37. Smyth MJ, Godfrey DI, Trapani JA. A fresh look at tumor immunosurveillance and immunotherapy. Nat Immunol 2001:2:293-9.
38. Reed JC. Apoptosis-targeted therapies for cancer. Cancer Cell 2003:3:17-22.
39. O'Brien S, Moore JO, Boyd TE, et al. Randomized phase III trial of fludarabine plus cyclophosphamide with or without oblimersen sodium (Bcl-2 antisense) in patients with relapsed or refractory chronic lymphocytic leukemia. J Clin Oncol 2007:25:1114-20.
40. Naumann U, Schmidt F, Wick W, et al. Adenoviral natural born killer gene therapy for malignant glioma. Hum Gene Ther 2003:14:1235-46.
41. Roy S, Bayly CI, Gareau Y, et al. Maintenance of caspase-3 proenzyme dormancy by an intrinsic ''safety catch'' regulatory tripeptide. Proc Natl Acad Sci USA 2001:98:6132-7.
42. Trachootham D, Zhou Y, Zhang H, et al. Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta- phenylethyl isothiocyanate. Cancer Cell 2006:10:241-52.
43. Schumacker PT. Reactive oxygen species in cancer cells: live by the sword, die by the sword. Cancer Cell 2006:10:175-6.
44. Waris G, Ahsan H. Reactive oxygen species: role in the development of cancer and various chronic conditions. J Carcinog 2006:5:14.
45. Pelicano H, Carney D, Huang P. ROS stress in cancer cells and therapeutic implications. Drug Resist Update 2004:7:97-110.
46. Philchenkov A. Caspases: potential targets for regulating cell death. J Cell Mol Med 2004:8:432-14.
47. Shariat SF, Desai S, Song W, et al. Adenovirus-mediated transfer of inducible caspases: A novel ''death switch'' gene therapeutic approach to prostate cancer. Cancer Res 2001:61:2562-71.
48. Foghsgaard L, Wissing D, Mauch D, et al. Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor. J Cell Biol 2001:153:999-1010.
49. Liu J, Guo Q, Chen B, et al. Cathepsin B and its interacting proteins, bikunin and TSRC1, correlate with TNF- induced apoptosis of ovarian cancer cells OV-90. FEBS Lett 2006;580:245-50.
50. Nagaraj NS, Vigneswaran N, Zacharias W. Cathepsin B mediates TRAIL-induced apoptosis in oral cancer cells. J Cancer Res Clin Oncol 2006;132:171-83.
51. Vigneswaran N, Wu J, Nagaraj N, et al. Differential susceptibility of metastatic and primary oral cancer cells to TRAIL-induced apoptosis. Int J Oncol 2005;26:103-12.
52. Garnett TO, Filippova M, Duerksen-Hughes PJ. Bid is cleaved upstream of caspase-8 activation during TRAIL-mediated apoptosis in human osteosarcoma cells. Apoptosis 2007;12:1299-315.
53. Guicciardi ME, Bronk SF, Werneburg NW, et al. cFLIPL prevents TRAIL-induced apoptosis of hepatocellular carcinoma cells by inhibiting the lysosomal pathway of apoptosis. Am J Physiol Gastrointest Liver Physiol 2007;292:G1337-46.
54. Jin S, White E. Role of autophagy in cancer. Autophagy 2007;3:28-31.
55. Levine B. Cell biology: autophagy and cancer. Nature 2007;446:745-7.
56. Degenhardt K, Mathew R, Beaudoin B, et al. Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 2006;10:51-64.
57. Karantza-Wadsworth V, Patel S, Kravchuk 0, et al. Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. Genes Dev 2007;21:1621-35.
58. Manning BD, Cantley LC. AKT/PKB signaling: navigating downstream. Cell 2007;129:1261-74.
59. Guertin DA, Sabatini DM. Defining the role of mTOR in cancer. Cancer Cell 2007;12:9-22.
60. Kondo Y, Kondo S. Autophagy and cancer therapy. Autophagy 2006;2:85-90.
61. Ding WX, Ni HM, Gao WT, et al. Linking of autophagy to ubiquitinproteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am J Pathol 2007;171:513-24.
62. Pandey UB, Nie ZP, Batlevi Y, et al. HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS. Nature 2007;447:859-63.
63. Roccaro AM, Hideshima T, Richardson PG, et al. Bortezomib as an antitumor agent. Curr Pharm Biotechnol 2006;7:441-8.
64. Vakkila J, Lotze MT. Opinion - Inflammation and necrosis promote tumour growth. Nat Rev Immunol 2004;4:641-8.
65. Zong WX, Ditsworth D, Bauer DE, et al. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev 2004;18:1272-82.
66. Agostinis P, Buytaert E, Breyssens H, et al. Regulatory pathways in photodynamic therapy induced apoptosis. Photochem Photobiol Sci 2004;3:721-9.
67. Almeida RD, Manadas BJ, Carvalho AP, et al. Intracellular signaling mechanisms in photodynamic therapy. Biochim Biophys Acta 2004;1704:59-86.
68. Hippert MM, 0'Toole PS, Thorburn A. Autophagy and cancer: good bad or both? Cancer Res 2006;66:9349-51.
69. Blagosklonny MV. Prospective strategies to enforce selectively cell death in cancer cells. Oncogene 2004;23:2967-75.
70. Yu L, Wan F, Dutta S, et al. Autophagic programmed cell death by selective catalase degradation. Proc Natl Acad Sci USA 2006;103:4952-7.
71. Wang ZH, Xu L, Duan ZL, et al. Beclin 1-mediated macroautophagy involves regulation of caspase-9 expression in cervical cancer HeLa cells. Gynecol Oncol 2007;107:107-13.
72. Pattingre S, Tassa A, Qu X, et al. Bcl-2 antiapoptotic proteins inhibit beclin 1- dependent autophagy. Cell 2005;122:927- 39.
73. Hoyer-Hansen M, Bastholm L, Szyniarowski P, et al. Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2. Mol Cell 2007;25:193- 205.
74. Crighton D, Wilkinson S, 0'Prey J, et al. DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 2006;126:121-34.
75. Mathew R, Karantza-Wadsworth V, White E. Role of autophagy in cancer. Nat Rev Cancer 2007;7:961-7.
76. Jin SK. Autophagy, mitochondrial quality control, and oncogenesis. Autophagy 2006;2:80-4.
77. Ravikumar B, Berger Z, Vacher C, et al. Rapamycin pre-treatment protects against apoptosis. Hum Mol Genet 2006;15:1209-16.
78. Klionsky DJ, Emr SD. Autophagy as a regulated pathway of cellular degradation. Science 2000;290:1717-21.
79. Boya P, Gonzalez-Polo RA, Casares N, et al. Inhibition of macroautophagy triggers apoptosis. Mol Cell Biol 2005;25:1025-40.
80. Golstein P, Kroemer G. Redundant cell death mechanisms as relics and backups. Cell Death Differ 2005;12 (Suppl 2):1490-6.
81. Degterev A, Yuan J. Expansion and evolution of cell death programmes. Nat Rev Mol Cell Bio 2008;9:378-90.
82. Zong WX, Ditsworth D, Bauer DE, et al. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev 2004;18:1272-82.
83. Jin S, DiPaola RS, Mathew R, et al. Metabolic catastrophe as a means to cancer cell death. J Cell Sci 2007;120:379-83.