-
1
-
-
2342486731
-
Parental cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults: A prospective study of parents and offspring
-
Lloyd-Jones DM, Nam BH, D'Agostino RB Sr., Levy D, Murabito JM, Wang TJ, Wilson PW, O'Donnell CJ : Parental cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults: A prospective study of parents and offspring. JAMA 2004 291 : 2204 2211.
-
(2004)
JAMA
, vol.291
, pp. 2204-2211
-
-
Lloyd-Jones, D.M.1
Nam, B.H.2
D'Agostino, Sr.R.B.3
Levy, D.4
Murabito, J.M.5
Wang, T.J.6
Wilson, P.W.7
O'Donnell, C.J.8
-
2
-
-
0036224099
-
Sudden death and myocardial infarction in first degree relatives as predictors of primary cardiac arrest
-
Friedlander Y, Siscovick DS, Arbogast P, Psaty BM, Weinmann S, Lemaitre RN, Raghunathan TE, Cobb LA : Sudden death and myocardial infarction in first degree relatives as predictors of primary cardiac arrest. Atherosclerosis 2002 162 : 211 216.
-
(2002)
Atherosclerosis
, vol.162
, pp. 211-216
-
-
Friedlander, Y.1
Siscovick, D.S.2
Arbogast, P.3
Psaty, B.M.4
Weinmann, S.5
Lemaitre, R.N.6
Raghunathan, T.E.7
Cobb, L.A.8
-
3
-
-
0033586647
-
Predicting sudden death in the population: The Paris Prospective Study i
-
Jouven X, Desnos M, Guerot C, Ducimetiere P : Predicting sudden death in the population: The Paris Prospective Study I. Circulation 1999 99 : 1978 1983.
-
(1999)
Circulation
, vol.99
, pp. 1978-1983
-
-
Jouven, X.1
Desnos, M.2
Guerot, C.3
Ducimetiere, P.4
-
4
-
-
34248512934
-
Clinical aspects of type-1 long-QT syndrome by location, coding type, and biophysical function of mutations involving the KCNQ1 gene
-
Moss AJ, Shimizu W, Wilde AA, Towbin JA, Zareba W, Robinson JL, Qi M, Vincent GM, Ackerman MJ, Kaufman ES, Hofman N, Seth R, Kamakura S, Miyamoto Y, Goldenberg I, Andrews ML, McNitt S : Clinical aspects of type-1 long-QT syndrome by location, coding type, and biophysical function of mutations involving the KCNQ1 gene. Circulation 2007 115 : 2481 2489.
-
(2007)
Circulation
, vol.115
, pp. 2481-2489
-
-
Moss, A.J.1
Shimizu, W.2
Wilde, A.A.3
Towbin, J.A.4
Zareba, W.5
Robinson, J.L.6
Qi, M.7
Vincent, G.M.8
Ackerman, M.J.9
Kaufman, E.S.10
Hofman, N.11
Seth, R.12
Kamakura, S.13
Miyamoto, Y.14
Goldenberg, I.15
Andrews, M.L.16
McNitt, S.17
-
5
-
-
34347210255
-
Inherited arrhythmia syndromes
-
Wilde AA, Tan HL : Inherited arrhythmia syndromes. Circ J 2007 71 (Suppl A A12 A19.
-
(2007)
Circ J
, vol.71
, Issue.SUPPL. A
-
-
Wilde, A.A.1
Tan, H.L.2
-
6
-
-
84873074477
-
-
hDatabase. Available at
-
hDatabase : Gene Connection for the Heart. Available at : http://www.fsm.it/cardmoc/.
-
Gene Connection for the Heart
-
-
-
7
-
-
14944363856
-
25th anniversary of the International Long-QT Syndrome Registry: An ongoing quest to uncover the secrets of long-QT syndrome
-
Moss AJ, Schwartz PJ. 25th anniversary of the International Long-QT Syndrome Registry: An ongoing quest to uncover the secrets of long-QT syndrome. Circulation 2005 111 : 1199 1201.
-
(2005)
Circulation
, vol.111
, pp. 1199-1201
-
-
Moss, A.J.1
Schwartz, P.J.2
-
8
-
-
33846186813
-
Long QT syndrome in adults
-
Sauer AJ, Moss AJ, McNitt S, Peterson DR, Zareba W, Robinson JL, Qi M, Goldenberg I, Hobbs JB, Ackerman MJ, Benhorin J, Hall WJ, Kaufman ES, Locati EH, Napolitano C, Priori SG, Schwartz PJ, Towbin JA, Vincent GM, Zhang L : Long QT syndrome in adults. J Am Coll Cardiol 2007 49 : 329 337.
-
(2007)
J Am Coll Cardiol
, vol.49
, pp. 329-337
-
-
Sauer, A.J.1
Moss, A.J.2
McNitt, S.3
Peterson, D.R.4
Zareba, W.5
Robinson, J.L.6
Qi, M.7
Goldenberg, I.8
Hobbs, J.B.9
Ackerman, M.J.10
Benhorin, J.11
Hall, W.J.12
Kaufman, E.S.13
Locati, E.H.14
Napolitano, C.15
Priori, S.G.16
Schwartz, P.J.17
Towbin, J.A.18
Vincent, G.M.19
Zhang, L.20
more..
-
9
-
-
38049146378
-
Clinical practice. Long-QT syndrome
-
Roden DM : Clinical practice. Long-QT syndrome. N Engl J Med 2008 358 : 169 176.
-
(2008)
N Engl J Med
, vol.358
, pp. 169-176
-
-
Roden, D.M.1
-
10
-
-
33748512585
-
Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia
-
di Barletta MR, Viatchenko-Karpinski S, Nori A, Memmi M, Terentyev D, Turcato F, Valle G, Rizzi N, Napolitano C, Gyorke S, Volpe P, Priori SG : Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia. Circulation 2006 114 : 1012 1019.
-
(2006)
Circulation
, vol.114
, pp. 1012-1019
-
-
Di Barletta, M.R.1
Viatchenko-Karpinski, S.2
Nori, A.3
Memmi, M.4
Terentyev, D.5
Turcato, F.6
Valle, G.7
Rizzi, N.8
Napolitano, C.9
Gyorke, S.10
Volpe, P.11
Priori, S.G.12
-
11
-
-
0347064347
-
Defective potassium channel Kir2.1 trafficking underlies Andersen-Tawil syndrome
-
Bendahhou S, Donaldson MR, Plaster NM, Tristani-Firouzi M, Fu YH, Ptacek LJ : Defective potassium channel Kir2.1 trafficking underlies Andersen-Tawil syndrome. J Biol Chem 2003 278 : 51779 51785.
-
(2003)
J Biol Chem
, vol.278
, pp. 51779-51785
-
-
Bendahhou, S.1
Donaldson, M.R.2
Plaster, N.M.3
Tristani-Firouzi, M.4
Fu, Y.H.5
Ptacek, L.J.6
-
12
-
-
5344223383
-
Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism
-
Splawski I, Timothy KW, Sharpe LM, Decher N, Kumar P, Bloise R, Napolitano C, Schwartz PJ, Joseph RM, Condouris K, Tager-Flusberg H, Priori SG, Sanguinetti MC, Keating MT : Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism. Cell 2004 119 : 19 31.
-
(2004)
Cell
, vol.119
, pp. 19-31
-
-
Splawski, I.1
Timothy, K.W.2
Sharpe, L.M.3
Decher, N.4
Kumar, P.5
Bloise, R.6
Napolitano, C.7
Schwartz, P.J.8
Joseph, R.M.9
Condouris, K.10
Tager-Flusberg, H.11
Priori, S.G.12
Sanguinetti, M.C.13
Keating, M.T.14
-
13
-
-
37549069795
-
Unmasking concealed long QT syndrome
-
Ackerman MJ. Unmasking concealed long QT syndrome. Heart Rhythm 2008 5 : 8 10.
-
(2008)
Heart Rhythm
, vol.5
, pp. 8-10
-
-
Ackerman, M.J.1
-
14
-
-
33846562077
-
Defining the cellular phenotype of "ankyrin-B syndrome" variants: Human ANK2 variants associated with clinical phenotypes display a spectrum of activities in cardiomyocytes
-
Mohler PJ, Le Scouarnec S, Denjoy I, Lowe JS, Guicheney P, Caron L, Driskell IM, Schott JJ, Norris K, Leenhardt A, Kim RB, Escande D, Roden DM : Defining the cellular phenotype of "ankyrin-B syndrome" variants: Human ANK2 variants associated with clinical phenotypes display a spectrum of activities in cardiomyocytes. Circulation 2007 115 : 432 441.
-
(2007)
Circulation
, vol.115
, pp. 432-441
-
-
Mohler, P.J.1
Le Scouarnec, S.2
Denjoy, I.3
Lowe, J.S.4
Guicheney, P.5
Caron, L.6
Driskell, I.M.7
Schott, J.J.8
Norris, K.9
Leenhardt, A.10
Kim, R.B.11
Escande, D.12
Roden, D.M.13
-
15
-
-
36049001507
-
Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias
-
London B, Michalec M, Mehdi H, Zhu X, Kerchner L, Sanyal S, Viswanathan PC, Pfahnl AE, Shang LL, Madhusudanan M, Baty CJ, Lagana S, Aleong R, Gutmann R, Ackerman MJ, McNamara DM, Weiss R, Dudley SC Jr. : Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias. Circulation 2007 116 : 2260 2268.
-
(2007)
Circulation
, vol.116
, pp. 2260-2268
-
-
London, B.1
Michalec, M.2
Mehdi, H.3
Zhu, X.4
Kerchner, L.5
Sanyal, S.6
Viswanathan, P.C.7
Pfahnl, A.E.8
Shang, L.L.9
Madhusudanan, M.10
Baty, C.J.11
Lagana, S.12
Aleong, R.13
Gutmann, R.14
Ackerman, M.J.15
McNamara, D.M.16
Weiss, R.17
Dudley, Jr.S.C.18
-
16
-
-
33646183895
-
Beta2-adrenergic receptor genetic variants and risk of sudden cardiac death
-
Sotoodehnia N, Siscovick DS, Vatta M, Psaty BM, Tracy RP, Towbin JA, Lemaitre RN, Rea TD, Durda JP, Chang JM, Lumley TS, Kuller LH, Burke GL, Heckbert SR : Beta2-adrenergic receptor genetic variants and risk of sudden cardiac death. Circulation 2006 113 : 1842 1848.
-
(2006)
Circulation
, vol.113
, pp. 1842-1848
-
-
Sotoodehnia, N.1
Siscovick, D.S.2
Vatta, M.3
Psaty, B.M.4
Tracy, R.P.5
Towbin, J.A.6
Lemaitre, R.N.7
Rea, T.D.8
Durda, J.P.9
Chang, J.M.10
Lumley, T.S.11
Kuller, L.H.12
Burke, G.L.13
Heckbert, S.R.14
-
17
-
-
38049169040
-
Mutation of an A-kinase-anchoring protein causes long-QT syndrome
-
Chen L, Marquardt ML, Tester DJ, Sampson KJ, Ackerman MJ, Kass RS : Mutation of an A-kinase-anchoring protein causes long-QT syndrome. Proc Natl Acad Sci USA 2007 104 : 20990 20995.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20990-20995
-
-
Chen, L.1
Marquardt, M.L.2
Tester, D.J.3
Sampson, K.J.4
Ackerman, M.J.5
Kass, R.S.6
-
18
-
-
40649127397
-
A splice site mutation in hERG leads to cryptic splicing in human long QT syndrome
-
Gong Q, Zhang L, Moss AJ, Vincent GM, Ackerman MJ, Robinson JC, Jones MA, Tester DJ, Zhou Z : A splice site mutation in hERG leads to cryptic splicing in human long QT syndrome. J Mol Cell Cardiol 2008 44 : 502 509.
-
(2008)
J Mol Cell Cardiol
, vol.44
, pp. 502-509
-
-
Gong, Q.1
Zhang, L.2
Moss, A.J.3
Vincent, G.M.4
Ackerman, M.J.5
Robinson, J.C.6
Jones, M.A.7
Tester, D.J.8
Zhou, Z.9
-
19
-
-
30444434576
-
Long QT syndrome caused by a large duplication in the KCNH2 (HERG) gene undetectable by current polymerase chain reaction-based exon-scanning methodologies
-
Koopmann TT, Alders M, Jongbloed RJ, Guerrero S, Mannens MM, Wilde AA, Bezzina CR : Long QT syndrome caused by a large duplication in the KCNH2 (HERG) gene undetectable by current polymerase chain reaction-based exon-scanning methodologies. Heart Rhythm 2006 3 : 52 55.
-
(2006)
Heart Rhythm
, vol.3
, pp. 52-55
-
-
Koopmann, T.T.1
Alders, M.2
Jongbloed, R.J.3
Guerrero, S.4
Mannens, M.M.5
Wilde, A.A.6
Bezzina, C.R.7
-
20
-
-
33644872001
-
Common sodium channel promoter haplotype in Asian subjects underlies variability in cardiac conduction
-
Bezzina CR, Shimizu W, Yang P, Koopmann TT, Tanck MW, Miyamoto Y, Kamakura S, Roden DM, Wilde AA : Common sodium channel promoter haplotype in Asian subjects underlies variability in cardiac conduction. Circulation 2006 113 : 338 344.
-
(2006)
Circulation
, vol.113
, pp. 338-344
-
-
Bezzina, C.R.1
Shimizu, W.2
Yang, P.3
Koopmann, T.T.4
Tanck, M.W.5
Miyamoto, Y.6
Kamakura, S.7
Roden, D.M.8
Wilde, A.A.9
-
21
-
-
65349144088
-
Polymorphisms in the cardiac sodium channel promoter displaying variant in vitro expression activity
-
Yang P, Koopmann TT, Pfeufer A, Jalilzadeh S, Schulze-Bahr E, Kaab S, Wilde AA, Roden DM, Bezzina CR : Polymorphisms in the cardiac sodium channel promoter displaying variant in vitro expression activity. Eur J Hum Genet 2007.
-
(2007)
Eur J Hum Genet
-
-
Yang, P.1
Koopmann, T.T.2
Pfeufer, A.3
Jalilzadeh, S.4
Schulze-Bahr, E.5
Kaab, S.6
Wilde, A.A.7
Roden, D.M.8
Bezzina, C.R.9
-
22
-
-
17144415220
-
Compendium of cardiac channel mutations in 541 consecutive unrelated patients referred for long QT syndrome genetic testing
-
Tester DJ, Will ML, Haglund CM, Ackerman MJ : Compendium of cardiac channel mutations in 541 consecutive unrelated patients referred for long QT syndrome genetic testing. Heart Rhythm 2005 2 : 507 517.
-
(2005)
Heart Rhythm
, vol.2
, pp. 507-517
-
-
Tester, D.J.1
Will, M.L.2
Haglund, C.M.3
Ackerman, M.J.4
-
23
-
-
1042268063
-
Inherited arrhythmogenic diseases: The complexity beyond monogenic disorders
-
Priori SG. Inherited arrhythmogenic diseases: The complexity beyond monogenic disorders. Circ Res 2004 94 : 140 145.
-
(2004)
Circ Res
, vol.94
, pp. 140-145
-
-
Priori, S.G.1
-
24
-
-
65349123923
-
-
OMIN. Available at. Online Mendelian Inheritance in Man.
-
OMIN : Available at : http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim. Online Mendelian Inheritance in Man.
-
-
-
-
25
-
-
35348983887
-
A second generation human haplotype map of over 3.1 million SNPs
-
International HapMap Consortium
-
International HapMap Consortium : A second generation human haplotype map of over 3.1 million SNPs. Nature 2007 449 : 851 861.
-
(2007)
Nature
, vol.449
, pp. 851-861
-
-
-
26
-
-
0035933044
-
Sudden cardiac death, genes, and arrhythmogenesis: Consideration of new population and mechanistic approaches from a National Heart, Lung, and Blood Institute workshop, Part II
-
Spooner PM, Albert C, Benjamin EJ, Boineau R, Elston RC, George AL Jr., Jouven X, Kuller LH, MacCluer JW, Marban E, Muller JE, Schwartz PJ, Siscovick DS, Tracy RP, Zareba W, Zipes DP : Sudden cardiac death, genes, and arrhythmogenesis: Consideration of new population and mechanistic approaches from a National Heart, Lung, and Blood Institute workshop, Part II. Circulation 2001 103 : 2447 2452.
-
(2001)
Circulation
, vol.103
, pp. 2447-2452
-
-
Spooner, P.M.1
Albert, C.2
Benjamin, E.J.3
Boineau, R.4
Elston, R.C.5
George, Jr.A.L.6
Jouven, X.7
Kuller, L.H.8
MacCluer, J.W.9
Marban, E.10
Muller, J.E.11
Schwartz, P.J.12
Siscovick, D.S.13
Tracy, R.P.14
Zareba, W.15
Zipes, D.P.16
-
27
-
-
38549106529
-
Interleukin-18 promoter polymorphism associates with the occurrence of sudden cardiac death among Caucasian males: The Helsinki Sudden Death Study
-
Hernesniemi JA, Karhunen PJ, Rontu R, Ilveskoski E, Kajander O, Goebeler S, Viiri LE, Pessi T, Hurme M, Lehtimaki T : Interleukin-18 promoter polymorphism associates with the occurrence of sudden cardiac death among Caucasian males: The Helsinki Sudden Death Study. Atherosclerosis 2008 196 : 643 649.
-
(2008)
Atherosclerosis
, vol.196
, pp. 643-649
-
-
Hernesniemi, J.A.1
Karhunen, P.J.2
Rontu, R.3
Ilveskoski, E.4
Kajander, O.5
Goebeler, S.6
Viiri, L.E.7
Pessi, T.8
Hurme, M.9
Lehtimaki, T.10
-
28
-
-
35748946613
-
Regulation of ion channels and arrhythmias in the ischemic heart
-
Akar JG, Akar FG : Regulation of ion channels and arrhythmias in the ischemic heart. J Electrocardiol 2007 40 : S37 S41.
-
(2007)
J Electrocardiol
, vol.40
-
-
Akar, J.G.1
Akar, F.G.2
-
29
-
-
34047275745
-
Gene expression signals involved in ischemic injury, extracellular matrix composition and fibrosis defined by global mRNA profiling of the human left ventricular myocardium
-
Gabrielsen A, Lawler PR, Yongzhong W, Steinbruchel D, Blagoja D, Paulsson-Berne G, Kastrup J, Hansson GK : Gene expression signals involved in ischemic injury, extracellular matrix composition and fibrosis defined by global mRNA profiling of the human left ventricular myocardium. J Mol Cell Cardiol 2007 42 : 870 883.
-
(2007)
J Mol Cell Cardiol
, vol.42
, pp. 870-883
-
-
Gabrielsen, A.1
Lawler, P.R.2
Yongzhong, W.3
Steinbruchel, D.4
Blagoja, D.5
Paulsson-Berne, G.6
Kastrup, J.7
Hansson, G.K.8
-
30
-
-
33846679386
-
Molecular biology of PCSK9: Its role in LDL metabolism
-
Horton JD, Cohen JC, Hobbs HH : Molecular biology of PCSK9: Its role in LDL metabolism. Trends Biochem Sci 2007 32 : 71 77.
-
(2007)
Trends Biochem Sci
, vol.32
, pp. 71-77
-
-
Horton, J.D.1
Cohen, J.C.2
Hobbs, H.H.3
-
31
-
-
33645103550
-
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
-
Cohen JC, Boerwinkle E, Mosley TH Jr., Hobbs HH : Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N Engl J Med 2006 354 : 1264 1272.
-
(2006)
N Engl J Med
, vol.354
, pp. 1264-1272
-
-
Cohen, J.C.1
Boerwinkle, E.2
Mosley, Jr.T.H.3
Hobbs, H.H.4
-
32
-
-
34248368106
-
Mechanisms of sudden cardiac death in myocardial infarction survivors: Insights from the randomized trials of implantable cardioverter-defibrillators
-
Bunch TJ, Hohnloser SH, Gersh BJ : Mechanisms of sudden cardiac death in myocardial infarction survivors: Insights from the randomized trials of implantable cardioverter-defibrillators. Circulation 2007 115 : 2451 2457.
-
(2007)
Circulation
, vol.115
, pp. 2451-2457
-
-
Bunch, T.J.1
Hohnloser, S.H.2
Gersh, B.J.3
-
33
-
-
0029092575
-
Subclinical disease as an independent risk factor for cardiovascular disease
-
Kuller LH, Shemanski L, Psaty BM, Borhani NO, Gardin J, Haan MN, O'Leary DH, Savage PJ, Tell GS, Tracy R : Subclinical disease as an independent risk factor for cardiovascular disease. Circulation 1995 92 : 720 726.
-
(1995)
Circulation
, vol.92
, pp. 720-726
-
-
Kuller, L.H.1
Shemanski, L.2
Psaty, B.M.3
Borhani, N.O.4
Gardin, J.5
Haan, M.N.6
O'Leary, D.H.7
Savage, P.J.8
Tell, G.S.9
Tracy, R.10
-
34
-
-
33749527092
-
Family history and the risk of sudden cardiac death as a manifestation of an acute coronary event
-
Kaikkonen KS, Kortelainen ML, Linna E, Huikuri HV : Family history and the risk of sudden cardiac death as a manifestation of an acute coronary event. Circulation 2006 114 : 1462 1467.
-
(2006)
Circulation
, vol.114
, pp. 1462-1467
-
-
Kaikkonen, K.S.1
Kortelainen, M.L.2
Linna, E.3
Huikuri, H.V.4
-
35
-
-
33748640974
-
Familial sudden death is an important risk factor for primary ventricular fibrillation: A case-control study in acute myocardial infarction patients
-
Dekker LR, Bezzina CR, Henriques JP, Tanck MW, Koch KT, Alings MW, Arnold AE, de Boer MJ, Gorgels AP, Michels HR, Verkerk A, Verheugt FW, Zijlstra F, Wilde AA : Familial sudden death is an important risk factor for primary ventricular fibrillation: A case-control study in acute myocardial infarction patients. Circulation 2006 114 : 1140 1145.
-
(2006)
Circulation
, vol.114
, pp. 1140-1145
-
-
Dekker, L.R.1
Bezzina, C.R.2
Henriques, J.P.3
Tanck, M.W.4
Koch, K.T.5
Alings, M.W.6
Arnold, A.E.7
De Boer, M.J.8
Gorgels, A.P.9
Michels, H.R.10
Verkerk, A.11
Verheugt, F.W.12
Zijlstra, F.13
Wilde, A.A.14
-
36
-
-
33645218746
-
Ventricular arrhythmias after acute myocardial infarction: A 20-year community study
-
Henkel DM, Witt BJ, Gersh BJ, Jacobsen SJ, Weston SA, Meverden RA, Roger VL : Ventricular arrhythmias after acute myocardial infarction: A 20-year community study. Am Heart J 2006 151 : 806 812.
-
(2006)
Am Heart J
, vol.151
, pp. 806-812
-
-
Henkel, D.M.1
Witt, B.J.2
Gersh, B.J.3
Jacobsen, S.J.4
Weston, S.A.5
Meverden, R.A.6
Roger, V.L.7
-
37
-
-
0033378863
-
Inherited long QT syndromes: A paradigm for understanding arrhythmogenesis
-
Roden DM, Spooner PM : Inherited long QT syndromes: A paradigm for understanding arrhythmogenesis. J Cardiovasc Electrophysiol 1999 10 : 1664 1683.
-
(1999)
J Cardiovasc Electrophysiol
, vol.10
, pp. 1664-1683
-
-
Roden, D.M.1
Spooner, P.M.2
-
38
-
-
0030066573
-
Molecular genetic insights into cardiovascular disease
-
Keating MT, Sanguinetti MC : Molecular genetic insights into cardiovascular disease. Science 1996 272 : 681 685.
-
(1996)
Science
, vol.272
, pp. 681-685
-
-
Keating, M.T.1
Sanguinetti, M.C.2
-
39
-
-
36048981858
-
Inherited arrhythmias: A National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion channel function
-
Lehnart SE, Ackerman MJ, Benson DW Jr., Brugada R, Clancy CE, Donahue JK, George AL Jr., Grant AO, Groft SC, January CT, Lathrop DA, Lederer WJ, Makielski JC, Mohler PJ, Moss A, Nerbonne JM, Olson TM, Przywara DA, Towbin JA, Wang LH, Marks AR. Inherited arrhythmias: A National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion channel function. Circulation 2007 116 : 2325 2345.
-
(2007)
Circulation
, vol.116
, pp. 2325-2345
-
-
Lehnart, S.E.1
Ackerman, M.J.2
Benson, Jr.D.W.3
Brugada, R.4
Clancy, C.E.5
Donahue, J.K.6
George, Jr.A.L.7
Grant, A.O.8
Groft, S.C.9
January, C.T.10
Lathrop, D.A.11
Lederer, W.J.12
Makielski, J.C.13
Mohler, P.J.14
Moss, A.15
Nerbonne, J.M.16
Olson, T.M.17
Przywara, D.A.18
Towbin, J.A.19
Wang, L.H.20
Marks, A.R.21
more..
-
40
-
-
33646777139
-
Allelic variants of SCN5A and risk of sudden cardiac arrest in patients with coronary artery disease
-
Stecker EC, Sono M, Wallace E, Gunson K, Jui J, Chugh SS : Allelic variants of SCN5A and risk of sudden cardiac arrest in patients with coronary artery disease. Heart Rhythm 2006 3 : 697 700.
-
(2006)
Heart Rhythm
, vol.3
, pp. 697-700
-
-
Stecker, E.C.1
Sono, M.2
Wallace, E.3
Gunson, K.4
Jui, J.5
Chugh, S.S.6
-
41
-
-
23844527207
-
Role of SCN5A Y1102 polymorphism in sudden cardiac death in blacks
-
Burke A, Creighton W, Mont E, Li L, Hogan S, Kutys R, Fowler D, Virmani R. Role of SCN5A Y1102 polymorphism in sudden cardiac death in blacks. Circulation 2005 112 : 798 802.
-
(2005)
Circulation
, vol.112
, pp. 798-802
-
-
Burke, A.1
Creighton, W.2
Mont, E.3
Li, L.4
Hogan, S.5
Kutys, R.6
Fowler, D.7
Virmani, R.8
-
42
-
-
18544383162
-
Variant of SCN5A sodium channel implicated in risk of cardiac arrhythmia
-
Splawski I, Timothy KW, Tateyama M, Clancy CE, Malhotra A, Beggs AH, Cappuccio FP, Sagnella GA, Kass RS, Keating MT. Variant of SCN5A sodium channel implicated in risk of cardiac arrhythmia. Science 2002 297 : 1333 1336.
-
(2002)
Science
, vol.297
, pp. 1333-1336
-
-
Splawski, I.1
Timothy, K.W.2
Tateyama, M.3
Clancy, C.E.4
Malhotra, A.5
Beggs, A.H.6
Cappuccio, F.P.7
Sagnella, G.A.8
Kass, R.S.9
Keating, M.T.10
-
43
-
-
43949101679
-
Postmortem molecular analysis of KCNQ1 and SCN5A genes in sudden unexplained death in young Australians
-
Doolan A, Langlois N, Chiu C, Ingles J, Lind JM, Semsarian C. Postmortem molecular analysis of KCNQ1 and SCN5A genes in sudden unexplained death in young Australians. Int J Cardiol 2008 127 : 138 141.
-
(2008)
Int J Cardiol
, vol.127
, pp. 138-141
-
-
Doolan, A.1
Langlois, N.2
Chiu, C.3
Ingles, J.4
Lind, J.M.5
Semsarian, C.6
-
44
-
-
37349080496
-
Cardiac sodium channel gene variants and sudden cardiac death in women
-
Albert CM, Nam EG, Rimm EB, Jin HW, Hajjar RJ, Hunter DJ, MacRae CA, Ellinor PT. Cardiac sodium channel gene variants and sudden cardiac death in women. Circulation 2008 117 : 16 23.
-
(2008)
Circulation
, vol.117
, pp. 16-23
-
-
Albert, C.M.1
Nam, E.G.2
Rimm, E.B.3
Jin, H.W.4
Hajjar, R.J.5
Hunter, D.J.6
MacRae, C.A.7
Ellinor, P.T.8
-
45
-
-
1542288322
-
The influence of gender on arrhythmias
-
Peters RW, Gold MR. The influence of gender on arrhythmias. Cardiol Rev 2004 12 : 97 105.
-
(2004)
Cardiol Rev
, vol.12
, pp. 97-105
-
-
Peters, R.W.1
Gold, M.R.2
-
46
-
-
30344462409
-
Prolonged QTc interval and risk of sudden cardiac death in a population of older adults
-
Straus SM, Kors JA, De Bruin ML, Van Der Hooft CS, Hofman A, Heeringa J, Deckers JW, Kingma JH, Sturkenboom MC, Stricker BH, Witteman JC : Prolonged QTc interval and risk of sudden cardiac death in a population of older adults. J Am Coll Cardiol 2006 47 : 362 367.
-
(2006)
J Am Coll Cardiol
, vol.47
, pp. 362-367
-
-
Straus, S.M.1
Kors, J.A.2
De Bruin, M.L.3
Van Der Hooft, C.S.4
Hofman, A.5
Heeringa, J.6
Deckers, J.W.7
Kingma, J.H.8
Sturkenboom, M.C.9
Stricker, B.H.10
Witteman, J.C.11
-
47
-
-
36348931620
-
The common long-QT syndrome mutation KCNQ1/A341V causes unusually severe clinical manifestations in patients with different ethnic backgrounds: Toward a mutation-specific risk stratification
-
Crotti L, Spazzolini C, Schwartz PJ, Shimizu W, Denjoy I, Schulze-Bahr E, Zaklyazminskaya EV, Swan H, Ackerman MJ, Moss AJ, Wilde AA, Horie M, Brink PA, Insolia R, De Ferrari GM, Crimi G : The common long-QT syndrome mutation KCNQ1/A341V causes unusually severe clinical manifestations in patients with different ethnic backgrounds: Toward a mutation-specific risk stratification. Circulation 2007 116 : 2366 2375.
-
(2007)
Circulation
, vol.116
, pp. 2366-2375
-
-
Crotti, L.1
Spazzolini, C.2
Schwartz, P.J.3
Shimizu, W.4
Denjoy, I.5
Schulze-Bahr, E.6
Zaklyazminskaya, E.V.7
Swan, H.8
Ackerman, M.J.9
Moss, A.J.10
Wilde, A.A.11
Horie, M.12
Brink, P.A.13
Insolia, R.14
De Ferrari, G.M.15
Crimi, G.16
-
48
-
-
26944485507
-
Spectrum and prevalence of cardiac ryanodine receptor (RyR2) mutations in a cohort of unrelated patients referred explicitly for long QT syndrome genetic testing
-
Tester DJ, Kopplin LJ, Will ML, Ackerman MJ : Spectrum and prevalence of cardiac ryanodine receptor (RyR2) mutations in a cohort of unrelated patients referred explicitly for long QT syndrome genetic testing. Heart Rhythm 2005 2 : 1099 1105.
-
(2005)
Heart Rhythm
, vol.2
, pp. 1099-1105
-
-
Tester, D.J.1
Kopplin, L.J.2
Will, M.L.3
Ackerman, M.J.4
-
49
-
-
29144494740
-
Genetic testing in the long QT syndrome: Development and validation of an efficient approach to genotyping in clinical practice
-
Napolitano C, Priori SG, Schwartz PJ, Bloise R, Ronchetti E, Nastoli J, Bottelli G, Cerrone M, Leonardi S : Genetic testing in the long QT syndrome: Development and validation of an efficient approach to genotyping in clinical practice. JAMA 2005 294 : 2975 2980.
-
(2005)
JAMA
, vol.294
, pp. 2975-2980
-
-
Napolitano, C.1
Priori, S.G.2
Schwartz, P.J.3
Bloise, R.4
Ronchetti, E.5
Nastoli, J.6
Bottelli, G.7
Cerrone, M.8
Leonardi, S.9
-
50
-
-
22544461665
-
Susceptibility genes and modifiers for cardiac arrhythmias
-
Kaab S, Schulze-Bahr E : Susceptibility genes and modifiers for cardiac arrhythmias. Cardiovasc Res 2005 67 : 397 413.
-
(2005)
Cardiovasc Res
, vol.67
, pp. 397-413
-
-
Kaab, S.1
Schulze-Bahr, E.2
-
51
-
-
7744243863
-
Spectrum and prevalence of cardiac sodium channel variants among black, white, Asian, and Hispanic individuals: Implications for arrhythmogenic susceptibility and Brugada/long QT syndrome genetic testing
-
Ackerman MJ, Splawski I, Makielski JC, Tester DJ, Will ML, Timothy KW, Keating MT, Jones G, Chadha M, Burrow CR, Stephens JC, Xu C, Judson R, Curran ME : Spectrum and prevalence of cardiac sodium channel variants among black, white, Asian, and Hispanic individuals: Implications for arrhythmogenic susceptibility and Brugada/long QT syndrome genetic testing. Heart Rhythm 2004 1 : 600 607.
-
(2004)
Heart Rhythm
, vol.1
, pp. 600-607
-
-
Ackerman, M.J.1
Splawski, I.2
Makielski, J.C.3
Tester, D.J.4
Will, M.L.5
Timothy, K.W.6
Keating, M.T.7
Jones, G.8
Chadha, M.9
Burrow, C.R.10
Stephens, J.C.11
Xu, C.12
Judson, R.13
Curran, M.E.14
-
52
-
-
39149084747
-
Outcome in African Americans and other minorities in the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)
-
Mitchell JE, Hellkamp AS, Mark DB, Anderson J, Poole JE, Lee KL, Bardy GH : Outcome in African Americans and other minorities in the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT). Am Heart J 2008 155 : 501 506.
-
(2008)
Am Heart J
, vol.155
, pp. 501-506
-
-
Mitchell, J.E.1
Hellkamp, A.S.2
Mark, D.B.3
Anderson, J.4
Poole, J.E.5
Lee, K.L.6
Bardy, G.H.7
-
53
-
-
0345690174
-
Ethnic differences in cardiac potassium channel variants: Implications for genetic susceptibility to sudden cardiac death and genetic testing for congenital long QT syndrome
-
Ackerman MJ, Tester DJ, Jones GS, Will ML, Burrow CR, Curran ME : Ethnic differences in cardiac potassium channel variants: Implications for genetic susceptibility to sudden cardiac death and genetic testing for congenital long QT syndrome. Mayo Clin Proc 2003 78 : 1479 1487.
-
(2003)
Mayo Clin Proc
, vol.78
, pp. 1479-1487
-
-
Ackerman, M.J.1
Tester, D.J.2
Jones, G.S.3
Will, M.L.4
Burrow, C.R.5
Curran, M.E.6
-
54
-
-
33846941214
-
The common non-synonymous variant G38S of the KCNE1-(minK)-gene is not associated to QT interval in Central European Caucasians: Results from the KORA study
-
Akyol M, Jalilzadeh S, Sinner MF, Perz S, Beckmann BM, Gieger C, Illig T, Wichmann HE, Meitinger T, Kaab S, Pfeufer A : The common non-synonymous variant G38S of the KCNE1-(minK)-gene is not associated to QT interval in Central European Caucasians: Results from the KORA study. Eur Heart J 2007 28 : 305 309.
-
(2007)
Eur Heart J
, vol.28
, pp. 305-309
-
-
Akyol, M.1
Jalilzadeh, S.2
Sinner, M.F.3
Perz, S.4
Beckmann, B.M.5
Gieger, C.6
Illig, T.7
Wichmann, H.E.8
Meitinger, T.9
Kaab, S.10
Pfeufer, A.11
-
55
-
-
34548382718
-
Common genetic variation in KCNH2 is associated with QT interval duration: The Framingham Heart Study
-
Newton-Cheh C, Guo CY, Larson MG, Musone SL, Surti A, Camargo AL, Drake JA, Benjamin EJ, Levy D, D'Agostino RB Sr., Hirschhorn JN, O'Donnell CJ : Common genetic variation in KCNH2 is associated with QT interval duration: The Framingham Heart Study. Circulation 2007 116 : 1128 1136.
-
(2007)
Circulation
, vol.116
, pp. 1128-1136
-
-
Newton-Cheh, C.1
Guo, C.Y.2
Larson, M.G.3
Musone, S.L.4
Surti, A.5
Camargo, A.L.6
Drake, J.A.7
Benjamin, E.J.8
Levy, D.9
D'Agostino, Sr.R.B.10
Hirschhorn, J.N.11
O'Donnell, C.J.12
-
56
-
-
0242330187
-
A ubiquitous splice variant and a common polymorphism affect heterologous expression of recombinant human SCN5A heart sodium channels
-
Makielski JC, Ye B, Valdivia CR, Pagel MD, Pu J, Tester DJ, Ackerman MJ : A ubiquitous splice variant and a common polymorphism affect heterologous expression of recombinant human SCN5A heart sodium channels. Circ Res 2003 93 : 821 828.
-
(2003)
Circ Res
, vol.93
, pp. 821-828
-
-
Makielski, J.C.1
Ye, B.2
Valdivia, C.R.3
Pagel, M.D.4
Pu, J.5
Tester, D.J.6
Ackerman, M.J.7
-
57
-
-
21344433631
-
Common human SCN5A polymorphisms have altered electrophysiology when expressed in Q1077 splice variants
-
Tan BH, Valdivia CR, Rok BA, Ye B, Ruwaldt KM, Tester DJ, Ackerman MJ, Makielski JC : Common human SCN5A polymorphisms have altered electrophysiology when expressed in Q1077 splice variants. Heart Rhythm 2005 2 : 741 747.
-
(2005)
Heart Rhythm
, vol.2
, pp. 741-747
-
-
Tan, B.H.1
Valdivia, C.R.2
Rok, B.A.3
Ye, B.4
Ruwaldt, K.M.5
Tester, D.J.6
Ackerman, M.J.7
Makielski, J.C.8
-
58
-
-
0031894666
-
Heritability of ECG measurements in adult male twins
-
Russell MW, Law I, Sholinsky P, Fabsitz RR : Heritability of ECG measurements in adult male twins. J Electrocardiol 1998 30 (Suppl 64 68.
-
(1998)
J Electrocardiol
, vol.30
, Issue.SUPPL.
, pp. 64-68
-
-
Russell, M.W.1
Law, I.2
Sholinsky, P.3
Fabsitz, R.R.4
-
59
-
-
33745237158
-
A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization
-
Arking DE, Pfeufer A, Post W, Kao WH, Newton-Cheh C, Ikeda M, West K, Kashuk C, Akyol M, Perz S, Jalilzadeh S, Illig T, Gieger C, Guo CY, Larson MG, Wichmann HE, Marban E, O'Donnell CJ, Hirschhorn JN, Kaab S, Spooner PM, Meitinger T, Chakravarti A : A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. Nat Genet 2006 38 : 644 651.
-
(2006)
Nat Genet
, vol.38
, pp. 644-651
-
-
Arking, D.E.1
Pfeufer, A.2
Post, W.3
Kao, W.H.4
Newton-Cheh, C.5
Ikeda, M.6
West, K.7
Kashuk, C.8
Akyol, M.9
Perz, S.10
Jalilzadeh, S.11
Illig, T.12
Gieger, C.13
Guo, C.Y.14
Larson, M.G.15
Wichmann, H.E.16
Marban, E.17
O'Donnell, C.J.18
Hirschhorn, J.N.19
Kaab, S.20
Spooner, P.M.21
Meitinger, T.22
Chakravarti, A.23
more..
-
61
-
-
42449098057
-
Association of NOS1AP genetic variants with QT interval duration in families from the Diabetes Heart Study
-
Lehtinen AB, Newton-Cheh C, Ziegler JT, Langefeld CD, Freedman BI, Daniel KR, Herrington DM, Bowden DW : Association of NOS1AP genetic variants with QT interval duration in families from the Diabetes Heart Study. Diabetes 2008 57 : 1108 1114.
-
(2008)
Diabetes
, vol.57
, pp. 1108-1114
-
-
Lehtinen, A.B.1
Newton-Cheh, C.2
Ziegler, J.T.3
Langefeld, C.D.4
Freedman, B.I.5
Daniel, K.R.6
Herrington, D.M.7
Bowden, D.W.8
-
62
-
-
27644511218
-
Does the CAPON gene confer susceptibility to schizophrenia?
-
Eastwood SL : Does the CAPON gene confer susceptibility to schizophrenia? PLoS Med 2005 2 : e348.
-
(2005)
PLoS Med
, vol.2
, pp. 348
-
-
Eastwood, S.L.1
-
63
-
-
34848913758
-
NO production results in suspension-induced muscle atrophy through dislocation of neuronal NOS
-
Suzuki N, Motohashi N, Uezumi A, Fukada S, Yoshimura T, Itoyama Y, Aoki M, Miyagoe-Suzuki Y, Takeda S : NO production results in suspension-induced muscle atrophy through dislocation of neuronal NOS. J Clin Invest 2007 117 : 2468 2476.
-
(2007)
J Clin Invest
, vol.117
, pp. 2468-2476
-
-
Suzuki, N.1
Motohashi, N.2
Uezumi, A.3
Fukada, S.4
Yoshimura, T.5
Itoyama, Y.6
Aoki, M.7
Miyagoe-Suzuki, Y.8
Takeda, S.9
-
64
-
-
34547765951
-
Action at a distance: Epigenetic silencing of large chromosomal regions in carcinogenesis
-
Clark SJ : Action at a distance: Epigenetic silencing of large chromosomal regions in carcinogenesis. Hum Mol Genet 2007 16 (Spec No 1 R88 R95.
-
(2007)
Hum Mol Genet
, vol.16
-
-
Clark, S.J.1
-
65
-
-
37349042225
-
Emerging role of microRNAs in cardiovascular biology
-
Latronico MV, Catalucci D, Condorelli G : Emerging role of microRNAs in cardiovascular biology. Circ Res 2007 101 : 1225 1236.
-
(2007)
Circ Res
, vol.101
, pp. 1225-1236
-
-
Latronico, M.V.1
Catalucci, D.2
Condorelli, G.3
-
66
-
-
34147153781
-
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2
-
Zhao Y, Ransom JF, Li A, Vedantham V, von Drehle M, Muth AN, Tsuchihashi T, McManus MT, Schwartz RJ, Srivastava D : Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell 2007 129 : 303 317.
-
(2007)
Cell
, vol.129
, pp. 303-317
-
-
Zhao, Y.1
Ransom, J.F.2
Li, A.3
Vedantham, V.4
Von Drehle, M.5
Muth, A.N.6
Tsuchihashi, T.7
McManus, M.T.8
Schwartz, R.J.9
Srivastava, D.10
-
67
-
-
34948829119
-
The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes
-
Xu C, Lu Y, Pan Z, Chu W, Luo X, Lin H, Xiao J, Shan H, Wang Z, Yang B : The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes. J Cell Sci 2007 120 : 3045 3052.
-
(2007)
J Cell Sci
, vol.120
, pp. 3045-3052
-
-
Xu, C.1
Lu, Y.2
Pan, Z.3
Chu, W.4
Luo, X.5
Lin, H.6
Xiao, J.7
Shan, H.8
Wang, Z.9
Yang, B.10
-
68
-
-
41949127122
-
CAPON modulates cardiac repolarization via neuronal nitric oxide synthase signaling in the heart
-
Chang K-C BA, Sasano T, Tetsuo, Kizana E, Kashiwakura Y, Zhang Y, Foster DB, Marbán E : CAPON modulates cardiac repolarization via neuronal nitric oxide synthase signaling in the heart. Proc Natl Acad Sci USA 2008 105 : 4477 4482.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 4477-4482
-
-
Chang -C K, B.A.1
Sasano, T.2
Tetsuo3
Kizana, E.4
Kashiwakura, Y.5
Zhang, Y.6
Foster, D.B.7
Marbán, E.8
-
69
-
-
65349117383
-
Genetic variations in NOS1AP predict sudden cardiac death in the general US while population
-
accepted for publication.
-
Kao WHL AD, Post W, Rea T, Sotoodehnia N, Prineas R, Bishe B, Doan B, Boerwinkle E, Psaty B, Tomaselli G, Coresh J, Siscovick D, Marban E, Spooner PM, Burke G, Chakravart A. Genetic variations in NOS1AP predict sudden cardiac death in the general US while population. Circulation 2008 accepted for publication.
-
(2008)
Circulation
-
-
Kao, W.H.L.1
Post, W.2
Rea, T.3
Sotoodehnia, N.4
Prineas, R.5
Bishe, B.6
Doan, B.7
Boerwinkle, E.8
Psaty, B.9
Tomaselli, G.10
Coresh, J.11
Siscovick, D.12
Marban, E.13
Spooner, P.M.14
Burke, G.15
Chakravart, A.16
-
70
-
-
53349100962
-
Gender and effects of a common genetic variant in the NOS1 regulator NOS1AP on cardiac repolarization in 3761 individuals from two independent populations
-
Tobin MD, Kahonen M, Braund P, Nieminen T, Hajat C, Tomaszewski M, Viik J, Lehtinen R, Ng GA, Macfarlane PW, Burton PR, Lehtimaki T, Samani NJ : Gender and effects of a common genetic variant in the NOS1 regulator NOS1AP on cardiac repolarization in 3761 individuals from two independent populations. Int J Epidemiol 2008 37 : 1132 1141.
-
(2008)
Int J Epidemiol
, vol.37
, pp. 1132-1141
-
-
Tobin, M.D.1
Kahonen, M.2
Braund, P.3
Nieminen, T.4
Hajat, C.5
Tomaszewski, M.6
Viik, J.7
Lehtinen, R.8
Ng, G.A.9
MacFarlane, P.W.10
Burton, P.R.11
Lehtimaki, T.12
Samani, N.J.13
-
71
-
-
34347335661
-
Common NOS1AP variants are associated with a prolonged QTc interval in the Rotterdam Study
-
Aarnoudse AJ, Newton-Cheh C, de Bakker PI, Straus SM, Kors JA, Hofman A, Uitterlinden AG, Witteman JC, Stricker BH : Common NOS1AP variants are associated with a prolonged QTc interval in the Rotterdam Study. Circulation 2007 116 : 10 16.
-
(2007)
Circulation
, vol.116
, pp. 10-16
-
-
Aarnoudse, A.J.1
Newton-Cheh, C.2
De Bakker, P.I.3
Straus, S.M.4
Kors, J.A.5
Hofman, A.6
Uitterlinden, A.G.7
Witteman, J.C.8
Stricker, B.H.9
-
72
-
-
46349106706
-
Common beta-adrenergic receptor polymorphisms are not associated with risk of sudden cardiac death in patients with coronary artery disease
-
Tseng ZH, Aouizerat BE, Pawlikowska L, Vittinghoff E, Lin F, Whiteman D, Poon A, Herrington D, Howard TD, Varosy PD, Hulley SB, Malloy M, Kane J, Kwok PY, Olgin JE : Common beta-adrenergic receptor polymorphisms are not associated with risk of sudden cardiac death in patients with coronary artery disease. Heart Rhythm 2008 5 : 814 821.
-
(2008)
Heart Rhythm
, vol.5
, pp. 814-821
-
-
Tseng, Z.H.1
Aouizerat, B.E.2
Pawlikowska, L.3
Vittinghoff, E.4
Lin, F.5
Whiteman, D.6
Poon, A.7
Herrington, D.8
Howard, T.D.9
Varosy, P.D.10
Hulley, S.B.11
Malloy, M.12
Kane, J.13
Kwok, P.Y.14
Olgin, J.E.15
-
73
-
-
34547623750
-
Genomewide association analysis of coronary artery disease
-
Samani NJ, Erdmann J, Hall AS, Hengstenberg C, Mangino M, Mayer B, Dixon RJ, Meitinger T, Braund P, Wichmann HE, Barrett JH, Konig IR, Stevens SE, Szymczak S, Tregouet DA, Iles MM, Pahlke F, Pollard H, Lieb W, Cambien F, Fischer M, Ouwehand W, Blankenberg S, Balmforth AJ, Baessler A, Ball SG, Strom TM, Braenne I, Gieger C, Deloukas P, Tobin MD, Ziegler A, Thompson JR, Schunkert H. Genomewide association analysis of coronary artery disease. N Engl J Med 2007 357 : 443 453.
-
(2007)
N Engl J Med
, vol.357
, pp. 443-453
-
-
Samani, N.J.1
Erdmann, J.2
Hall, A.S.3
Hengstenberg, C.4
Mangino, M.5
Mayer, B.6
Dixon, R.J.7
Meitinger, T.8
Braund, P.9
Wichmann, H.E.10
Barrett, J.H.11
Konig, I.R.12
Stevens, S.E.13
Szymczak, S.14
Tregouet, D.A.15
Iles, M.M.16
Pahlke, F.17
Pollard, H.18
Lieb, W.19
Cambien, F.20
Fischer, M.21
Ouwehand, W.22
Blankenberg, S.23
Balmforth, A.J.24
Baessler, A.25
Ball, S.G.26
Strom, T.M.27
Braenne, I.28
Gieger, C.29
Deloukas, P.30
Tobin, M.D.31
Ziegler, A.32
Thompson, J.R.33
Schunkert, H.34
more..
-
74
-
-
34249996115
-
A common allele on chromosome 9 associated with coronary heart disease
-
McPherson R, Pertsemlidis A, Kavaslar N, Stewart A, Roberts R, Cox DR, Hinds DA, Pennacchio LA, Tybjaerg-Hansen A, Folsom AR, Boerwinkle E, Hobbs HH, Cohen JC : A common allele on chromosome 9 associated with coronary heart disease. Science 2007 316 : 1488 1491.
-
(2007)
Science
, vol.316
, pp. 1488-1491
-
-
McPherson, R.1
Pertsemlidis, A.2
Kavaslar, N.3
Stewart, A.4
Roberts, R.5
Cox, D.R.6
Hinds, D.A.7
Pennacchio, L.A.8
Tybjaerg-Hansen, A.9
Folsom, A.R.10
Boerwinkle, E.11
Hobbs, H.H.12
Cohen, J.C.13
-
75
-
-
38649091662
-
The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm
-
Helgadottir A, Thorleifsson G, Magnusson KP, Gretarsdottir S, Steinthorsdottir V, Manolescu A, Jones GT, Rinkel GJ, Blankensteijn JD, Ronkainen A, Jaaskelainen JE, Kyo Y, Lenk GM, Sakalihasan N, Kostulas K, Gottsater A, Flex A, Stefansson H, Hansen T, Andersen G, Weinsheimer S, Borch-Johnsen K, Jorgensen T, Shah SH, Quyyumi AA, Granger CB, Reilly MP, Austin H, Levey AI, Vaccarino V, Palsdottir E, Walters GB, Jonsdottir T, Snorradottir S, Magnusdottir D, Gudmundsson G, Ferrell RE, Sveinbjornsdottir S, Hernesniemi J, Niemela M, Limet R, Andersen K, Sigurdsson G, Benediktsson R, Verhoeven EL, Teijink JA, Grobbee DE, Rader DJ, Collier DA, Pedersen O, Pola R, Hillert J, Lindblad B, Valdimarsson EM, Magnadottir HB, Wijmenga C, Tromp G, Baas AF, Ruigrok YM, van Rij AM, Kuivaniemi H, Powell JT, Matthiasson SE, Gulcher JR, Thorgeirsson G, Kong A, Thorsteinsdottir U, Stefansson K : The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. Nat Genet 2008 40 : 217 224.
-
(2008)
Nat Genet
, vol.40
, pp. 217-224
-
-
Helgadottir, A.1
Thorleifsson, G.2
Magnusson, K.P.3
Gretarsdottir, S.4
Steinthorsdottir, V.5
Manolescu, A.6
Jones, G.T.7
Rinkel, G.J.8
Blankensteijn, J.D.9
Ronkainen, A.10
Jaaskelainen, J.E.11
Kyo, Y.12
Lenk, G.M.13
Sakalihasan, N.14
Kostulas, K.15
Gottsater, A.16
Flex, A.17
Stefansson, H.18
Hansen, T.19
Andersen, G.20
Weinsheimer, S.21
Borch-Johnsen, K.22
Jorgensen, T.23
Shah, S.H.24
Quyyumi, A.A.25
Granger, C.B.26
Reilly, M.P.27
Austin, H.28
Levey, A.I.29
Vaccarino, V.30
Palsdottir, E.31
Walters, G.B.32
Jonsdottir, T.33
Snorradottir, S.34
Magnusdottir, D.35
Gudmundsson, G.36
Ferrell, R.E.37
Sveinbjornsdottir, S.38
Hernesniemi, J.39
Niemela, M.40
Limet, R.41
Andersen, K.42
Sigurdsson, G.43
Benediktsson, R.44
Verhoeven, E.L.45
Teijink, J.A.46
Grobbee, D.E.47
Rader, D.J.48
Collier, D.A.49
Pedersen, O.50
Pola, R.51
Hillert, J.52
Lindblad, B.53
Valdimarsson, E.M.54
Magnadottir, H.B.55
Wijmenga, C.56
Tromp, G.57
Baas, A.F.58
Ruigrok, Y.M.59
Van Rij, A.M.60
Kuivaniemi, H.61
Powell, J.T.62
Matthiasson, S.E.63
Gulcher, J.R.64
Thorgeirsson, G.65
Kong, A.66
Thorsteinsdottir, U.67
Stefansson, K.68
more..
-
76
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PI, Chen H, Roix JJ, Kathiresan S, Hirschhorn JN, Daly MJ, Hughes TE, Groop L, Altshuler D, Almgren P, Florez JC, Meyer J, Ardlie K, Bengtsson Bostrom K, Isomaa B, Lettre G, Lindblad U, Lyon HN, Melander O, Newton-Cheh C, Nilsson P, Orho-Melander M, Rastam L, Speliotes EK, Taskinen MR, Tuomi T, Guiducci C, Berglund A, Carlson J, Gianniny L, Hackett R, Hall L, Holmkvist J, Laurila E, Sjogren M, Sterner M, Surti A, Svensson M, Tewhey R, Blumenstiel B, Parkin M, Defelice M, Barry R, Brodeur W, Camarata J, Chia N, Fava M, Gibbons J, Handsaker B, Healy C, Nguyen K, Gates C, Sougnez C, Gage D, Nizzari M, Gabriel SB, Chirn GW, Ma Q, Parikh H, Richardson D, Ricke D, Purcell S : Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007 316 : 1331 1336.
-
(2007)
Science
, vol.316
, pp. 1331-1336
-
-
Saxena, R.1
Voight, B.F.2
Lyssenko, V.3
Burtt, N.P.4
De Bakker, P.I.5
Chen, H.6
Roix, J.J.7
Kathiresan, S.8
Hirschhorn, J.N.9
Daly, M.J.10
Hughes, T.E.11
Groop, L.12
Altshuler, D.13
Almgren, P.14
Florez, J.C.15
Meyer, J.16
Ardlie, K.17
Bengtsson Bostrom, K.18
Isomaa, B.19
Lettre, G.20
Lindblad, U.21
Lyon, H.N.22
Melander, O.23
Newton-Cheh, C.24
Nilsson, P.25
Orho-Melander, M.26
Rastam, L.27
Speliotes, E.K.28
Taskinen, M.R.29
Tuomi, T.30
Guiducci, C.31
Berglund, A.32
Carlson, J.33
Gianniny, L.34
Hackett, R.35
Hall, L.36
Holmkvist, J.37
Laurila, E.38
Sjogren, M.39
Sterner, M.40
Surti, A.41
Svensson, M.42
Tewhey, R.43
Blumenstiel, B.44
Parkin, M.45
Defelice, M.46
Barry, R.47
Brodeur, W.48
Camarata, J.49
Chia, N.50
Fava, M.51
Gibbons, J.52
Handsaker, B.53
Healy, C.54
Nguyen, K.55
Gates, C.56
Sougnez, C.57
Gage, D.58
Nizzari, M.59
Gabriel, S.B.60
Chirn, G.W.61
Ma, Q.62
Parikh, H.63
Richardson, D.64
Ricke, D.65
Purcell, S.66
more..
-
77
-
-
34249885875
-
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
-
Scott LJ, Mohlke KL, Bonnycastle LL, Willer CJ, Li Y, Duren WL, Erdos MR, Stringham HM, Chines PS, Jackson AU, Prokunina-Olsson L, Ding CJ, Swift AJ, Narisu N, Hu T, Pruim R, Xiao R, Li XY, Conneely KN, Riebow NL, Sprau AG, Tong M, White PP, Hetrick KN, Barnhart MW, Bark CW, Goldstein JL, Watkins L, Xiang F, Saramies J, Buchanan TA, Watanabe RM, Valle TT, Kinnunen L, Abecasis GR, Pugh EW, Doheny KF, Bergman RN, Tuomilehto J, Collins FS, Boehnke M : A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 2007 316 : 1341 1345.
-
(2007)
Science
, vol.316
, pp. 1341-1345
-
-
Scott, L.J.1
Mohlke, K.L.2
Bonnycastle, L.L.3
Willer, C.J.4
Li, Y.5
Duren, W.L.6
Erdos, M.R.7
Stringham, H.M.8
Chines, P.S.9
Jackson, A.U.10
Prokunina-Olsson, L.11
Ding, C.J.12
Swift, A.J.13
Narisu, N.14
Hu, T.15
Pruim, R.16
Xiao, R.17
Li, X.Y.18
Conneely, K.N.19
Riebow, N.L.20
Sprau, A.G.21
Tong, M.22
White, P.P.23
Hetrick, K.N.24
Barnhart, M.W.25
Bark, C.W.26
Goldstein, J.L.27
Watkins, L.28
Xiang, F.29
Saramies, J.30
Buchanan, T.A.31
Watanabe, R.M.32
Valle, T.T.33
Kinnunen, L.34
Abecasis, G.R.35
Pugh, E.W.36
Doheny, K.F.37
Bergman, R.N.38
Tuomilehto, J.39
Collins, F.S.40
Boehnke, M.41
more..
-
78
-
-
34347341846
-
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
-
Todd JA, Walker NM, Cooper JD, Smyth DJ, Downes K, Plagnol V, Bailey R, Nejentsev S, Field SF, Payne F, Lowe CE, Szeszko JS, Hafler JP, Zeitels L, Yang JH, Vella A, Nutland S, Stevens HE, Schuilenburg H, Coleman G, Maisuria M, Meadows W, Smink LJ, Healy B, Burren OS, Lam AA, Ovington NR, Allen J, Adlem E, Leung HT, Wallace C, Howson JM, Guja C, Ionescu-Tirgoviste C, Simmonds MJ, Heward JM, Gough SC, Dunger DB, Wicker LS, Clayton DG : Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet 2007 39 : 857 864.
-
(2007)
Nat Genet
, vol.39
, pp. 857-864
-
-
Todd, J.A.1
Walker, N.M.2
Cooper, J.D.3
Smyth, D.J.4
Downes, K.5
Plagnol, V.6
Bailey, R.7
Nejentsev, S.8
Field, S.F.9
Payne, F.10
Lowe, C.E.11
Szeszko, J.S.12
Hafler, J.P.13
Zeitels, L.14
Yang, J.H.15
Vella, A.16
Nutland, S.17
Stevens, H.E.18
Schuilenburg, H.19
Coleman, G.20
Maisuria, M.21
Meadows, W.22
Smink, L.J.23
Healy, B.24
Burren, O.S.25
Lam, A.A.26
Ovington, N.R.27
Allen, J.28
Adlem, E.29
Leung, H.T.30
Wallace, C.31
Howson, J.M.32
Guja, C.33
Ionescu-Tirgoviste, C.34
Simmonds, M.J.35
Heward, J.M.36
Gough, S.C.37
Dunger, D.B.38
Wicker, L.S.39
Clayton, D.G.40
more..
-
79
-
-
34447515621
-
Variants conferring risk of atrial fibrillation on chromosome 4q25
-
Gudbjartsson DF, Arnar DO, Helgadottir A, Gretarsdottir S, Holm H, Sigurdsson A, Jonasdottir A, Baker A, Thorleifsson G, Kristjansson K, Palsson A, Blondal T, Sulem P, Backman VM, Hardarson GA, Palsdottir E, Helgason A, Sigurjonsdottir R, Sverrisson JT, Kostulas K, Ng MC, Baum L, So WY, Wong KS, Chan JC, Furie KL, Greenberg SM, Sale M, Kelly P, MacRae CA, Smith EE, Rosand J, Hillert J, Ma RC, Ellinor PT, Thorgeirsson G, Gulcher JR, Kong A, Thorsteinsdottir U, Stefansson K : Variants conferring risk of atrial fibrillation on chromosome 4q25. Nature 2007 448 : 353 357.
-
(2007)
Nature
, vol.448
, pp. 353-357
-
-
Gudbjartsson, D.F.1
Arnar, D.O.2
Helgadottir, A.3
Gretarsdottir, S.4
Holm, H.5
Sigurdsson, A.6
Jonasdottir, A.7
Baker, A.8
Thorleifsson, G.9
Kristjansson, K.10
Palsson, A.11
Blondal, T.12
Sulem, P.13
Backman, V.M.14
Hardarson, G.A.15
Palsdottir, E.16
Helgason, A.17
Sigurjonsdottir, R.18
Sverrisson, J.T.19
Kostulas, K.20
Ng, M.C.21
Baum, L.22
So, W.Y.23
Wong, K.S.24
Chan, J.C.25
Furie, K.L.26
Greenberg, S.M.27
Sale, M.28
Kelly, P.29
MacRae, C.A.30
Smith, E.E.31
Rosand, J.32
Hillert, J.33
Ma, R.C.34
Ellinor, P.T.35
Thorgeirsson, G.36
Gulcher, J.R.37
Kong, A.38
Thorsteinsdottir, U.39
Stefansson, K.40
more..
-
80
-
-
34548849168
-
TRAF1-C5 as a risk locus for rheumatoid arthritis-a genomewide study
-
Plenge RM, Seielstad M, Padyukov L, Lee AT, Remmers EF, Ding B, Liew A, Khalili H, Chandrasekaran A, Davies LR, Li W, Tan AK, Bonnard C, Ong RT, Thalamuthu A, Pettersson S, Liu C, Tian C, Chen WV, Carulli JP, Beckman EM, Altshuler D, Alfredsson L, Criswell LA, Amos CI, Seldin MF, Kastner DL, Klareskog L, Gregersen PK : TRAF1-C5 as a risk locus for rheumatoid arthritis-a genomewide study. N Engl J Med 2007 357 : 1199 1209.
-
(2007)
N Engl J Med
, vol.357
, pp. 1199-1209
-
-
Plenge, R.M.1
Seielstad, M.2
Padyukov, L.3
Lee, A.T.4
Remmers, E.F.5
Ding, B.6
Liew, A.7
Khalili, H.8
Chandrasekaran, A.9
Davies, L.R.10
Li, W.11
Tan, A.K.12
Bonnard, C.13
Ong, R.T.14
Thalamuthu, A.15
Pettersson, S.16
Liu, C.17
Tian, C.18
Chen, W.V.19
Carulli, J.P.20
Beckman, E.M.21
Altshuler, D.22
Alfredsson, L.23
Criswell, L.A.24
Amos, C.I.25
Seldin, M.F.26
Kastner, D.L.27
Klareskog, L.28
Gregersen, P.K.29
more..
-
81
-
-
34548299105
-
Risk alleles for multiple sclerosis identified by a genomewide study
-
Hafler DA, Compston A, Sawcer S, Lander ES, Daly MJ, De Jager PL, de Bakker PI, Gabriel SB, Mirel DB, Ivinson AJ, Pericak-Vance MA, Gregory SG, Rioux JD, McCauley JL, Haines JL, Barcellos LF, Cree B, Oksenberg JR, Hauser SL : Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 2007 357 : 851 862.
-
(2007)
N Engl J Med
, vol.357
, pp. 851-862
-
-
Hafler, D.A.1
Compston, A.2
Sawcer, S.3
Lander, E.S.4
Daly, M.J.5
De Jager, P.L.6
De Bakker, P.I.7
Gabriel, S.B.8
Mirel, D.B.9
Ivinson, A.J.10
Pericak-Vance, M.A.11
Gregory, S.G.12
Rioux, J.D.13
McCauley, J.L.14
Haines, J.L.15
Barcellos, L.F.16
Cree, B.17
Oksenberg, J.R.18
Hauser, S.L.19
-
82
-
-
34548083742
-
Whole-genome analysis of sporadic amyotrophic lateral sclerosis
-
Dunckley T, Huentelman MJ, Craig DW, Pearson JV, Szelinger S, Joshipura K, Halperin RF, Stamper C, Jensen KR, Letizia D, Hesterlee SE, Pestronk A, Levine T, Bertorini T, Graves MC, Mozaffar T, Jackson CE, Bosch P, McVey A, Dick A, Barohn R, Lomen-Hoerth C, Rosenfeld J, O'Connor D T, Zhang K, Crook R, Ryberg H, Hutton M, Katz J, Simpson EP, Mitsumoto H, Bowser R, Miller RG, Appel SH, Stephan DA : Whole-genome analysis of sporadic amyotrophic lateral sclerosis. N Engl J Med 2007 357 : 775 788.
-
(2007)
N Engl J Med
, vol.357
, pp. 775-788
-
-
Dunckley, T.1
Huentelman, M.J.2
Craig, D.W.3
Pearson, J.V.4
Szelinger, S.5
Joshipura, K.6
Halperin, R.F.7
Stamper, C.8
Jensen, K.R.9
Letizia, D.10
Hesterlee, S.E.11
Pestronk, A.12
Levine, T.13
Bertorini, T.14
Graves, M.C.15
Mozaffar, T.16
Jackson, C.E.17
Bosch, P.18
McVey, A.19
Dick, A.20
Barohn, R.21
Lomen-Hoerth, C.22
Rosenfeld, J.23
O'Connor, D.T.24
Zhang, K.25
Crook, R.26
Ryberg, H.27
Hutton, M.28
Katz, J.29
Simpson, E.P.30
Mitsumoto, H.31
Bowser, R.32
Miller, R.G.33
Appel, S.H.34
Stephan, D.A.35
more..
-
83
-
-
13144306071
-
Genome-wide association studies for common diseases and complex traits
-
Hirschhorn JN, Daly MJ : Genome-wide association studies for common diseases and complex traits. Nat Rev Genet 2005 6 : 95 108.
-
(2005)
Nat Rev Genet
, vol.6
, pp. 95-108
-
-
Hirschhorn, J.N.1
Daly, M.J.2
-
84
-
-
34147095310
-
The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2
-
Yang B, Lin H, Xiao J, Lu Y, Luo X, Li B, Zhang Y, Xu C, Bai Y, Wang H, Chen G, Wang Z : The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2. Nat Med 2007 13 : 486 491.
-
(2007)
Nat Med
, vol.13
, pp. 486-491
-
-
Yang, B.1
Lin, H.2
Xiao, J.3
Lu, Y.4
Luo, X.5
Li, B.6
Zhang, Y.7
Xu, C.8
Bai, Y.9
Wang, H.10
Chen, G.11
Wang, Z.12
-
85
-
-
34249088350
-
Genome-wide transcription and the implications for genomic organization
-
Kapranov P, Willingham AT, Gingeras TR : Genome-wide transcription and the implications for genomic organization. Nat Rev Genet 2007 8 : 413 423.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 413-423
-
-
Kapranov, P.1
Willingham, A.T.2
Gingeras, T.R.3
-
86
-
-
34250305146
-
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
-
ENCODE Project Consortium
-
ENCODE Project Consortium : Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 2007 447 : 799 816.
-
(2007)
Nature
, vol.447
, pp. 799-816
-
-
-
87
-
-
34250308428
-
Origin of phenotypes: Genes and transcripts
-
Gingeras TR : Origin of phenotypes: Genes and transcripts. Genome Res 2007 17 : 682 690.
-
(2007)
Genome Res
, vol.17
, pp. 682-690
-
-
Gingeras, T.R.1
-
89
-
-
44349132708
-
Common and rare variants in multifactorial susceptibility to common diseases
-
Bodmer W, Bonilla C : Common and rare variants in multifactorial susceptibility to common diseases. Nat Genet 2008 40 : 695 701.
-
(2008)
Nat Genet
, vol.40
, pp. 695-701
-
-
Bodmer, W.1
Bonilla, C.2
-
90
-
-
34547647432
-
Summary of the American Heart Association's scientific statement on the relevance of genetics and genomics for prevention and treatment of cardiovascular disease
-
Arnett DK : Summary of the American Heart Association's scientific statement on the relevance of genetics and genomics for prevention and treatment of cardiovascular disease. Arterioscler Thromb Vasc Biol 2007 27 : 1682 1686.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 1682-1686
-
-
Arnett, D.K.1
-
91
-
-
24644524532
-
Mechanisms of sudden cardiac death
-
Rubart M, Zipes DP : Mechanisms of sudden cardiac death. J Clin Invest 2005 115 : 2305 2315.
-
(2005)
J Clin Invest
, vol.115
, pp. 2305-2315
-
-
Rubart, M.1
Zipes, D.P.2
-
92
-
-
65349106298
-
Long QT syndrome genes modulate the effect of NOS1AP haplotypes on cardiac repolarization
-
Tomas M SI, Bloise R, Napolitano C, Lazzarini C, Chakravarti A, Marban E, Spooner PM, Priori SG : Long QT syndrome genes modulate the effect of NOS1AP haplotypes on cardiac repolarization. Circulation 2007 116 : ll 663.
-
(2007)
Circulation
, vol.116
, pp. 663
-
-
Si, T.M.1
Bloise, R.2
Napolitano, C.3
Lazzarini, C.4
Chakravarti, A.5
Marban, E.6
Spooner, P.M.7
Priori, S.G.8
|