메뉴 건너뛰기




Volumn 20, Issue 5, 2009, Pages 585-596

Sudden cardiac death: The larger problem... the larger genome

Author keywords

Genomics; NOS1AP; Sudden cardiac death

Indexed keywords

BRUGADA SYNDROME; CARDIOVASCULAR RISK; DEFIBRILLATOR; DISEASE PREDISPOSITION; ETHNICITY; GENDER; GENE EXPRESSION; GENE MUTATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOME; GENOMICS; GENOTYPE; HAZARD RATIO; HEART DEATH; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE TACHYCARDIA; HUMAN; PHENOTYPE; PRIORITY JOURNAL; PROPHYLAXIS; QRS COMPLEX; QT PROLONGATION; REVIEW; SHORT QT SYNDROME; SINGLE NUCLEOTIDE POLYMORPHISM; SUDDEN DEATH;

EID: 65349160903     PISSN: 10453873     EISSN: 15408167     Source Type: Journal    
DOI: 10.1111/j.1540-8167.2008.01419.x     Document Type: Review
Times cited : (20)

References (92)
  • 1
    • 2342486731 scopus 로고    scopus 로고
    • Parental cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults: A prospective study of parents and offspring
    • Lloyd-Jones DM, Nam BH, D'Agostino RB Sr., Levy D, Murabito JM, Wang TJ, Wilson PW, O'Donnell CJ : Parental cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults: A prospective study of parents and offspring. JAMA 2004 291 : 2204 2211.
    • (2004) JAMA , vol.291 , pp. 2204-2211
    • Lloyd-Jones, D.M.1    Nam, B.H.2    D'Agostino, Sr.R.B.3    Levy, D.4    Murabito, J.M.5    Wang, T.J.6    Wilson, P.W.7    O'Donnell, C.J.8
  • 3
    • 0033586647 scopus 로고    scopus 로고
    • Predicting sudden death in the population: The Paris Prospective Study i
    • Jouven X, Desnos M, Guerot C, Ducimetiere P : Predicting sudden death in the population: The Paris Prospective Study I. Circulation 1999 99 : 1978 1983.
    • (1999) Circulation , vol.99 , pp. 1978-1983
    • Jouven, X.1    Desnos, M.2    Guerot, C.3    Ducimetiere, P.4
  • 5
    • 34347210255 scopus 로고    scopus 로고
    • Inherited arrhythmia syndromes
    • Wilde AA, Tan HL : Inherited arrhythmia syndromes. Circ J 2007 71 (Suppl A A12 A19.
    • (2007) Circ J , vol.71 , Issue.SUPPL. A
    • Wilde, A.A.1    Tan, H.L.2
  • 6
    • 84873074477 scopus 로고    scopus 로고
    • hDatabase. Available at
    • hDatabase : Gene Connection for the Heart. Available at : http://www.fsm.it/cardmoc/.
    • Gene Connection for the Heart
  • 7
    • 14944363856 scopus 로고    scopus 로고
    • 25th anniversary of the International Long-QT Syndrome Registry: An ongoing quest to uncover the secrets of long-QT syndrome
    • Moss AJ, Schwartz PJ. 25th anniversary of the International Long-QT Syndrome Registry: An ongoing quest to uncover the secrets of long-QT syndrome. Circulation 2005 111 : 1199 1201.
    • (2005) Circulation , vol.111 , pp. 1199-1201
    • Moss, A.J.1    Schwartz, P.J.2
  • 9
    • 38049146378 scopus 로고    scopus 로고
    • Clinical practice. Long-QT syndrome
    • Roden DM : Clinical practice. Long-QT syndrome. N Engl J Med 2008 358 : 169 176.
    • (2008) N Engl J Med , vol.358 , pp. 169-176
    • Roden, D.M.1
  • 13
    • 37549069795 scopus 로고    scopus 로고
    • Unmasking concealed long QT syndrome
    • Ackerman MJ. Unmasking concealed long QT syndrome. Heart Rhythm 2008 5 : 8 10.
    • (2008) Heart Rhythm , vol.5 , pp. 8-10
    • Ackerman, M.J.1
  • 19
    • 30444434576 scopus 로고    scopus 로고
    • Long QT syndrome caused by a large duplication in the KCNH2 (HERG) gene undetectable by current polymerase chain reaction-based exon-scanning methodologies
    • Koopmann TT, Alders M, Jongbloed RJ, Guerrero S, Mannens MM, Wilde AA, Bezzina CR : Long QT syndrome caused by a large duplication in the KCNH2 (HERG) gene undetectable by current polymerase chain reaction-based exon-scanning methodologies. Heart Rhythm 2006 3 : 52 55.
    • (2006) Heart Rhythm , vol.3 , pp. 52-55
    • Koopmann, T.T.1    Alders, M.2    Jongbloed, R.J.3    Guerrero, S.4    Mannens, M.M.5    Wilde, A.A.6    Bezzina, C.R.7
  • 22
    • 17144415220 scopus 로고    scopus 로고
    • Compendium of cardiac channel mutations in 541 consecutive unrelated patients referred for long QT syndrome genetic testing
    • Tester DJ, Will ML, Haglund CM, Ackerman MJ : Compendium of cardiac channel mutations in 541 consecutive unrelated patients referred for long QT syndrome genetic testing. Heart Rhythm 2005 2 : 507 517.
    • (2005) Heart Rhythm , vol.2 , pp. 507-517
    • Tester, D.J.1    Will, M.L.2    Haglund, C.M.3    Ackerman, M.J.4
  • 23
    • 1042268063 scopus 로고    scopus 로고
    • Inherited arrhythmogenic diseases: The complexity beyond monogenic disorders
    • Priori SG. Inherited arrhythmogenic diseases: The complexity beyond monogenic disorders. Circ Res 2004 94 : 140 145.
    • (2004) Circ Res , vol.94 , pp. 140-145
    • Priori, S.G.1
  • 24
    • 65349123923 scopus 로고    scopus 로고
    • OMIN. Available at. Online Mendelian Inheritance in Man.
    • OMIN : Available at : http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim. Online Mendelian Inheritance in Man.
  • 25
    • 35348983887 scopus 로고    scopus 로고
    • A second generation human haplotype map of over 3.1 million SNPs
    • International HapMap Consortium
    • International HapMap Consortium : A second generation human haplotype map of over 3.1 million SNPs. Nature 2007 449 : 851 861.
    • (2007) Nature , vol.449 , pp. 851-861
  • 28
    • 35748946613 scopus 로고    scopus 로고
    • Regulation of ion channels and arrhythmias in the ischemic heart
    • Akar JG, Akar FG : Regulation of ion channels and arrhythmias in the ischemic heart. J Electrocardiol 2007 40 : S37 S41.
    • (2007) J Electrocardiol , vol.40
    • Akar, J.G.1    Akar, F.G.2
  • 29
    • 34047275745 scopus 로고    scopus 로고
    • Gene expression signals involved in ischemic injury, extracellular matrix composition and fibrosis defined by global mRNA profiling of the human left ventricular myocardium
    • Gabrielsen A, Lawler PR, Yongzhong W, Steinbruchel D, Blagoja D, Paulsson-Berne G, Kastrup J, Hansson GK : Gene expression signals involved in ischemic injury, extracellular matrix composition and fibrosis defined by global mRNA profiling of the human left ventricular myocardium. J Mol Cell Cardiol 2007 42 : 870 883.
    • (2007) J Mol Cell Cardiol , vol.42 , pp. 870-883
    • Gabrielsen, A.1    Lawler, P.R.2    Yongzhong, W.3    Steinbruchel, D.4    Blagoja, D.5    Paulsson-Berne, G.6    Kastrup, J.7    Hansson, G.K.8
  • 30
    • 33846679386 scopus 로고    scopus 로고
    • Molecular biology of PCSK9: Its role in LDL metabolism
    • Horton JD, Cohen JC, Hobbs HH : Molecular biology of PCSK9: Its role in LDL metabolism. Trends Biochem Sci 2007 32 : 71 77.
    • (2007) Trends Biochem Sci , vol.32 , pp. 71-77
    • Horton, J.D.1    Cohen, J.C.2    Hobbs, H.H.3
  • 31
    • 33645103550 scopus 로고    scopus 로고
    • Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
    • Cohen JC, Boerwinkle E, Mosley TH Jr., Hobbs HH : Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N Engl J Med 2006 354 : 1264 1272.
    • (2006) N Engl J Med , vol.354 , pp. 1264-1272
    • Cohen, J.C.1    Boerwinkle, E.2    Mosley, Jr.T.H.3    Hobbs, H.H.4
  • 32
    • 34248368106 scopus 로고    scopus 로고
    • Mechanisms of sudden cardiac death in myocardial infarction survivors: Insights from the randomized trials of implantable cardioverter-defibrillators
    • Bunch TJ, Hohnloser SH, Gersh BJ : Mechanisms of sudden cardiac death in myocardial infarction survivors: Insights from the randomized trials of implantable cardioverter-defibrillators. Circulation 2007 115 : 2451 2457.
    • (2007) Circulation , vol.115 , pp. 2451-2457
    • Bunch, T.J.1    Hohnloser, S.H.2    Gersh, B.J.3
  • 34
    • 33749527092 scopus 로고    scopus 로고
    • Family history and the risk of sudden cardiac death as a manifestation of an acute coronary event
    • Kaikkonen KS, Kortelainen ML, Linna E, Huikuri HV : Family history and the risk of sudden cardiac death as a manifestation of an acute coronary event. Circulation 2006 114 : 1462 1467.
    • (2006) Circulation , vol.114 , pp. 1462-1467
    • Kaikkonen, K.S.1    Kortelainen, M.L.2    Linna, E.3    Huikuri, H.V.4
  • 37
    • 0033378863 scopus 로고    scopus 로고
    • Inherited long QT syndromes: A paradigm for understanding arrhythmogenesis
    • Roden DM, Spooner PM : Inherited long QT syndromes: A paradigm for understanding arrhythmogenesis. J Cardiovasc Electrophysiol 1999 10 : 1664 1683.
    • (1999) J Cardiovasc Electrophysiol , vol.10 , pp. 1664-1683
    • Roden, D.M.1    Spooner, P.M.2
  • 38
    • 0030066573 scopus 로고    scopus 로고
    • Molecular genetic insights into cardiovascular disease
    • Keating MT, Sanguinetti MC : Molecular genetic insights into cardiovascular disease. Science 1996 272 : 681 685.
    • (1996) Science , vol.272 , pp. 681-685
    • Keating, M.T.1    Sanguinetti, M.C.2
  • 40
    • 33646777139 scopus 로고    scopus 로고
    • Allelic variants of SCN5A and risk of sudden cardiac arrest in patients with coronary artery disease
    • Stecker EC, Sono M, Wallace E, Gunson K, Jui J, Chugh SS : Allelic variants of SCN5A and risk of sudden cardiac arrest in patients with coronary artery disease. Heart Rhythm 2006 3 : 697 700.
    • (2006) Heart Rhythm , vol.3 , pp. 697-700
    • Stecker, E.C.1    Sono, M.2    Wallace, E.3    Gunson, K.4    Jui, J.5    Chugh, S.S.6
  • 43
    • 43949101679 scopus 로고    scopus 로고
    • Postmortem molecular analysis of KCNQ1 and SCN5A genes in sudden unexplained death in young Australians
    • Doolan A, Langlois N, Chiu C, Ingles J, Lind JM, Semsarian C. Postmortem molecular analysis of KCNQ1 and SCN5A genes in sudden unexplained death in young Australians. Int J Cardiol 2008 127 : 138 141.
    • (2008) Int J Cardiol , vol.127 , pp. 138-141
    • Doolan, A.1    Langlois, N.2    Chiu, C.3    Ingles, J.4    Lind, J.M.5    Semsarian, C.6
  • 45
    • 1542288322 scopus 로고    scopus 로고
    • The influence of gender on arrhythmias
    • Peters RW, Gold MR. The influence of gender on arrhythmias. Cardiol Rev 2004 12 : 97 105.
    • (2004) Cardiol Rev , vol.12 , pp. 97-105
    • Peters, R.W.1    Gold, M.R.2
  • 48
    • 26944485507 scopus 로고    scopus 로고
    • Spectrum and prevalence of cardiac ryanodine receptor (RyR2) mutations in a cohort of unrelated patients referred explicitly for long QT syndrome genetic testing
    • Tester DJ, Kopplin LJ, Will ML, Ackerman MJ : Spectrum and prevalence of cardiac ryanodine receptor (RyR2) mutations in a cohort of unrelated patients referred explicitly for long QT syndrome genetic testing. Heart Rhythm 2005 2 : 1099 1105.
    • (2005) Heart Rhythm , vol.2 , pp. 1099-1105
    • Tester, D.J.1    Kopplin, L.J.2    Will, M.L.3    Ackerman, M.J.4
  • 50
    • 22544461665 scopus 로고    scopus 로고
    • Susceptibility genes and modifiers for cardiac arrhythmias
    • Kaab S, Schulze-Bahr E : Susceptibility genes and modifiers for cardiac arrhythmias. Cardiovasc Res 2005 67 : 397 413.
    • (2005) Cardiovasc Res , vol.67 , pp. 397-413
    • Kaab, S.1    Schulze-Bahr, E.2
  • 52
    • 39149084747 scopus 로고    scopus 로고
    • Outcome in African Americans and other minorities in the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)
    • Mitchell JE, Hellkamp AS, Mark DB, Anderson J, Poole JE, Lee KL, Bardy GH : Outcome in African Americans and other minorities in the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT). Am Heart J 2008 155 : 501 506.
    • (2008) Am Heart J , vol.155 , pp. 501-506
    • Mitchell, J.E.1    Hellkamp, A.S.2    Mark, D.B.3    Anderson, J.4    Poole, J.E.5    Lee, K.L.6    Bardy, G.H.7
  • 53
    • 0345690174 scopus 로고    scopus 로고
    • Ethnic differences in cardiac potassium channel variants: Implications for genetic susceptibility to sudden cardiac death and genetic testing for congenital long QT syndrome
    • Ackerman MJ, Tester DJ, Jones GS, Will ML, Burrow CR, Curran ME : Ethnic differences in cardiac potassium channel variants: Implications for genetic susceptibility to sudden cardiac death and genetic testing for congenital long QT syndrome. Mayo Clin Proc 2003 78 : 1479 1487.
    • (2003) Mayo Clin Proc , vol.78 , pp. 1479-1487
    • Ackerman, M.J.1    Tester, D.J.2    Jones, G.S.3    Will, M.L.4    Burrow, C.R.5    Curran, M.E.6
  • 56
    • 0242330187 scopus 로고    scopus 로고
    • A ubiquitous splice variant and a common polymorphism affect heterologous expression of recombinant human SCN5A heart sodium channels
    • Makielski JC, Ye B, Valdivia CR, Pagel MD, Pu J, Tester DJ, Ackerman MJ : A ubiquitous splice variant and a common polymorphism affect heterologous expression of recombinant human SCN5A heart sodium channels. Circ Res 2003 93 : 821 828.
    • (2003) Circ Res , vol.93 , pp. 821-828
    • Makielski, J.C.1    Ye, B.2    Valdivia, C.R.3    Pagel, M.D.4    Pu, J.5    Tester, D.J.6    Ackerman, M.J.7
  • 58
  • 62
    • 27644511218 scopus 로고    scopus 로고
    • Does the CAPON gene confer susceptibility to schizophrenia?
    • Eastwood SL : Does the CAPON gene confer susceptibility to schizophrenia? PLoS Med 2005 2 : e348.
    • (2005) PLoS Med , vol.2 , pp. 348
    • Eastwood, S.L.1
  • 64
    • 34547765951 scopus 로고    scopus 로고
    • Action at a distance: Epigenetic silencing of large chromosomal regions in carcinogenesis
    • Clark SJ : Action at a distance: Epigenetic silencing of large chromosomal regions in carcinogenesis. Hum Mol Genet 2007 16 (Spec No 1 R88 R95.
    • (2007) Hum Mol Genet , vol.16
    • Clark, S.J.1
  • 65
    • 37349042225 scopus 로고    scopus 로고
    • Emerging role of microRNAs in cardiovascular biology
    • Latronico MV, Catalucci D, Condorelli G : Emerging role of microRNAs in cardiovascular biology. Circ Res 2007 101 : 1225 1236.
    • (2007) Circ Res , vol.101 , pp. 1225-1236
    • Latronico, M.V.1    Catalucci, D.2    Condorelli, G.3
  • 67
    • 34948829119 scopus 로고    scopus 로고
    • The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes
    • Xu C, Lu Y, Pan Z, Chu W, Luo X, Lin H, Xiao J, Shan H, Wang Z, Yang B : The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes. J Cell Sci 2007 120 : 3045 3052.
    • (2007) J Cell Sci , vol.120 , pp. 3045-3052
    • Xu, C.1    Lu, Y.2    Pan, Z.3    Chu, W.4    Luo, X.5    Lin, H.6    Xiao, J.7    Shan, H.8    Wang, Z.9    Yang, B.10
  • 83
    • 13144306071 scopus 로고    scopus 로고
    • Genome-wide association studies for common diseases and complex traits
    • Hirschhorn JN, Daly MJ : Genome-wide association studies for common diseases and complex traits. Nat Rev Genet 2005 6 : 95 108.
    • (2005) Nat Rev Genet , vol.6 , pp. 95-108
    • Hirschhorn, J.N.1    Daly, M.J.2
  • 85
    • 34249088350 scopus 로고    scopus 로고
    • Genome-wide transcription and the implications for genomic organization
    • Kapranov P, Willingham AT, Gingeras TR : Genome-wide transcription and the implications for genomic organization. Nat Rev Genet 2007 8 : 413 423.
    • (2007) Nat Rev Genet , vol.8 , pp. 413-423
    • Kapranov, P.1    Willingham, A.T.2    Gingeras, T.R.3
  • 86
    • 34250305146 scopus 로고    scopus 로고
    • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
    • ENCODE Project Consortium
    • ENCODE Project Consortium : Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 2007 447 : 799 816.
    • (2007) Nature , vol.447 , pp. 799-816
  • 87
    • 34250308428 scopus 로고    scopus 로고
    • Origin of phenotypes: Genes and transcripts
    • Gingeras TR : Origin of phenotypes: Genes and transcripts. Genome Res 2007 17 : 682 690.
    • (2007) Genome Res , vol.17 , pp. 682-690
    • Gingeras, T.R.1
  • 89
    • 44349132708 scopus 로고    scopus 로고
    • Common and rare variants in multifactorial susceptibility to common diseases
    • Bodmer W, Bonilla C : Common and rare variants in multifactorial susceptibility to common diseases. Nat Genet 2008 40 : 695 701.
    • (2008) Nat Genet , vol.40 , pp. 695-701
    • Bodmer, W.1    Bonilla, C.2
  • 90
    • 34547647432 scopus 로고    scopus 로고
    • Summary of the American Heart Association's scientific statement on the relevance of genetics and genomics for prevention and treatment of cardiovascular disease
    • Arnett DK : Summary of the American Heart Association's scientific statement on the relevance of genetics and genomics for prevention and treatment of cardiovascular disease. Arterioscler Thromb Vasc Biol 2007 27 : 1682 1686.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1682-1686
    • Arnett, D.K.1
  • 91
    • 24644524532 scopus 로고    scopus 로고
    • Mechanisms of sudden cardiac death
    • Rubart M, Zipes DP : Mechanisms of sudden cardiac death. J Clin Invest 2005 115 : 2305 2315.
    • (2005) J Clin Invest , vol.115 , pp. 2305-2315
    • Rubart, M.1    Zipes, D.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.