-
2
-
-
0004078385
-
-
Academic Press, San Diego, USA
-
Non-Viral Vectors for Gene Therapy. Huang L, Hung M-C, Wagner E (Eds), Academic Press, San Diego, USA (1999). A comprehensive monograph on non-viral gene vectors. A second edition is in preparation.
-
(1999)
Non-Viral Vectors for Gene Therapy
-
-
Huang, L.1
Hung, M.-C.2
Wagner, E.3
-
3
-
-
1642503835
-
-
See the recent reviews in Curr. Med. Chem. (2004) 11:133-220. A series of reviews on structure, function and theory of lipid-based gene vectors.
-
(2004)
Curr. Med. Chem.
, vol.11
, pp. 133-220
-
-
-
4
-
-
0037805642
-
-
For another series of recent reviews see Curr. Med. Chem. (2003) 10:1185-1315. A series of reviews primarily on the chemical aspects of lipid-based gene vectors.
-
(2003)
Curr. Med. Chem.
, vol.10
, pp. 1185-1315
-
-
-
5
-
-
0026430686
-
Gene therapeutics
-
FELGNER PL, RHODES G: Gene therapeutics. Nature (1991) 349:351-352. A historical overview of non-viral methods.
-
(1991)
Nature
, vol.349
, pp. 351-352
-
-
Felgner, P.L.1
Rhodes, G.2
-
6
-
-
0002265662
-
Gene delivery - Without viruses
-
HENRY CM: Gene delivery -without viruses. Chem. Eng. News (2001) 79:35-41.
-
(2001)
Chem. Eng. News
, vol.79
, pp. 35-41
-
-
Henry, C.M.1
-
7
-
-
0035941087
-
Gene therapy: Safer and virus-free?
-
FERBER D: Gene therapy: safer and virus-free? Science (2001) 294:1638-1642.
-
(2001)
Science
, vol.294
, pp. 1638-1642
-
-
Ferber, D.1
-
8
-
-
0036954247
-
Gene therapy progress and prospects: Nonviral vectors
-
NIIDOME T, HUANG L: Gene therapy progress and prospects: Nonviral vectors. Gene Ther. (2002) 9:1647-1652. A recent critical review of non-viral methods with a therapeutic outlook.
-
(2002)
Gene Ther.
, vol.9
, pp. 1647-1652
-
-
Niidome, T.1
Huang, L.2
-
9
-
-
0033902946
-
Structure and function of lipid-DNA complexes for gene delivery
-
CHESNOY S, HUANG L: Structure and function of lipid-DNA complexes for gene delivery. Ann. Rev. Biophys. Biomol. Struct. (2000) 29:27-47. A comprehensive review on synthetic gene delivery systems, including clinical and corporate work.
-
(2000)
Ann. Rev. Biophys. Biomol. Struct.
, vol.29
, pp. 27-47
-
-
Chesnoy, S.1
Huang, L.2
-
10
-
-
0031159392
-
Overcoming the obstacles to gene therapy
-
FRIEDMANN T: Overcoming the obstacles to gene therapy. Sci. Am. (1997) 276:96-101.
-
(1997)
Sci. Am.
, vol.276
, pp. 96-101
-
-
Friedmann, T.1
-
11
-
-
0032965398
-
Cationic lipid-mediated gene transfer: Current concepts
-
CLARK PR, HERSH EM: Cationic lipid-mediated gene transfer: current concepts. Curr. Opin. Mol. Ther. (1999) 1:158-176. A review of human clinical trials applying lipid vectors.
-
(1999)
Curr. Opin. Mol. Ther.
, vol.1
, pp. 158-176
-
-
Clark, P.R.1
Hersh, E.M.2
-
12
-
-
0032479769
-
Cationic liposomes for gene therapy
-
MILLER AD: Cationic liposomes for gene therapy. Angew. Chem. Int. Ed. (1998) 37:1768-1785. A thorough and comprehensive review of the chemistry of earlier lipid systems.
-
(1998)
Angew. Chem. Int. Ed.
, vol.37
, pp. 1768-1785
-
-
Miller, A.D.1
-
13
-
-
0023447252
-
Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure
-
FELGNER PL, GADEK TR, HOLM M et al.: Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc. Natl. Acad. Sci. USA (1987) 84:7413-7417. The paper that introduced lipofection.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 7413-7417
-
-
Felgner, P.L.1
Gadek, T.R.2
Holm, M.3
-
15
-
-
0027517321
-
Direct gene transfer with dna-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans
-
NABEL G, NABEL E, YANG Z et al.: Direct gene transfer with dna-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans. Proc. Natl. Acad. Sci. USA (1993) 90:11307-11311.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11307-11311
-
-
Nabel, G.1
Nabel, E.2
Yang, Z.3
-
16
-
-
4444370799
-
Gene therapy clinical trials worldwide 1989-2004 - An overview
-
EDELSTEIN ML, ABEDI MR, WIXON J, EDELSTEIN RM: Gene therapy clinical trials worldwide 1989-2004 - an overview. J. Gene Med. (2004) 6:597-602. A thorough overview of the available data on gene therapy clinical trials.
-
(2004)
J. Gene Med.
, vol.6
, pp. 597-602
-
-
Edelstein, M.L.1
Abedi, M.R.2
Wixon, J.3
Edelstein, R.M.4
-
17
-
-
0142089747
-
Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
-
RAPER SE, CHIRMULE N, LEE FS et al.: Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer. Mol. Genet. Metab. (2003) 80:148-158.
-
(2003)
Mol. Genet. Metab.
, vol.80
, pp. 148-158
-
-
Raper, S.E.1
Chirmule, N.2
Lee, F.S.3
-
18
-
-
0034724857
-
Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease
-
CAVAZZANA-CALVO M, HACEIN-BEY S, DE SAINT BASILE G et al.: Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease Science (2000) 288:669-672.
-
(2000)
Science
, vol.288
, pp. 669-672
-
-
Cavazzana-Calvo, M.1
Hacein-Bey, S.2
De Saint Basile, G.3
-
19
-
-
0037448352
-
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
-
HACEIN-BEY-ABINA S, VON KALLE C, SCHMIDT M et al.: A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N. Engl. J. Med. (2003) 348:255-256.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 255-256
-
-
Hacein-Bey-Abina, S.1
Von Kalle, C.2
Schmidt, M.3
-
20
-
-
0142084745
-
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
-
HACEIN-BEY-ABINA S, VON KALLE C, SCHMIDT M et al.: LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science (2003) 302:415-419.
-
(2003)
Science
, vol.302
, pp. 415-419
-
-
Hacein-Bey-Abina, S.1
Von Kalle, C.2
Schmidt, M.3
-
21
-
-
0031036238
-
Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes
-
RÄDLER JO, KOLTOVER I, SALDITT T, SAFINYA CR: Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes. Science (1997) 275:810-814. The first description of the lamellar phase of CL-DNA complexes.
-
(1997)
Science
, vol.275
, pp. 810-814
-
-
Rädler, J.O.1
Koltover, I.2
Salditt, T.3
Safinya, C.R.4
-
22
-
-
0032479572
-
An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA Release and delivery
-
KOLTOVER I, SALDITT T, RÄDLER JO, SAFINYA CR: An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA Release and delivery. Science (1998) 281:78-81. The first description of the inverted hexagonal phase of CL-DNA complexes.
-
(1998)
Science
, vol.281
, pp. 78-81
-
-
Koltover, I.1
Salditt, T.2
Rädler, J.O.3
Safinya, C.R.4
-
23
-
-
0031058241
-
The structure of DNA-liposome complexes
-
LASIC DD, STREY H, STUART MC, PODGORNIK R, FREDERIK PM: The structure of DNA-liposome complexes. J. Am. Chem. Soc. (1997) 119:832-833.
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 832-833
-
-
Lasic, D.D.1
Strey, H.2
Stuart, M.C.3
Podgornik, R.4
Frederik, P.M.5
-
24
-
-
0030910465
-
Formation of de novo centromeres and construction of first-generation human artificial microchromosomes
-
HARRINGTON JJ, VAN BOKKELEN G, MAYS RW, GUSTASHAW K, WILLIARD HF: Formation of de novo centromeres and construction of first-generation human artificial microchromosomes. Nat. Genet. (1997) 15:345-355.
-
(1997)
Nat. Genet.
, vol.15
, pp. 345-355
-
-
Harrington, J.J.1
Van Bokkelen, G.2
Mays, R.W.3
Gustashaw, K.4
Williard, H.F.5
-
25
-
-
0034680527
-
Genomics and gene therapy: Artificial chromosomes coming to life
-
WILLARD HF: Genomics and gene therapy: artificial chromosomes coming to life. Science (2000) 290:1308-1309.
-
(2000)
Science
, vol.290
, pp. 1308-1309
-
-
Willard, H.F.1
-
26
-
-
0038482054
-
The problem with cationic liposome/micelle-based non-viral vector systems for gene therapy
-
MILLER AD: The problem with cationic liposome/micelle-based non-viral vector systems for gene therapy. Curr. Med. Chem. (2003) 10:1195-1211. A recent review with a focus on newer platform technologies for the future.
-
(2003)
Curr. Med. Chem.
, vol.10
, pp. 1195-1211
-
-
Miller, A.D.1
-
27
-
-
0032805569
-
Phase diagram, stability and overcharging of lamellar cationic lipid - DNA self assembled complexes
-
KOLTOVER I, SALDITT T, SAFINYA CR: Phase diagram, stability and overcharging of lamellar cationic lipid - DNA self assembled complexes. Biophys. J. (1999) 77:915-924.
-
(1999)
Biophys. J.
, vol.77
, pp. 915-924
-
-
Koltover, I.1
Salditt, T.2
Safinya, C.R.3
-
28
-
-
6144272654
-
Two-dimensional smectic ordering of linear DNA chains in self-assembled DNA-cationic liposome mixtures
-
SALDITT T, KOLTOVER I, RÄDLER JO, SAFINYA CR: Two-dimensional smectic ordering of linear DNA chains in self-assembled DNA-cationic liposome mixtures. Phys. Rev. Lett. (1997) 79:2582-2585.
-
(1997)
Phys. Rev. Lett.
, vol.79
, pp. 2582-2585
-
-
Salditt, T.1
Koltover, I.2
Rädler, J.O.3
Safinya, C.R.4
-
29
-
-
0035425499
-
Structures of lipid-DNA complexes: Supramolecular assembly and gene delivery
-
SAFINYA CR: Structures of lipid-DNA complexes: supramolecular assembly and gene delivery. Curr. Opin. Struct. Biol. (2001) 11:440-448.
-
(2001)
Curr. Opin. Struct. Biol.
, vol.11
, pp. 440-448
-
-
Safinya, C.R.1
-
31
-
-
0037622183
-
Three-dimensional imaging of lipid gene-carriers: Membrane charge density controls universal transfection behavior in lamellar cationic liposome-DNA complexes
-
LIN AJ, SLACK NL, AHMAD A, GEORGE CX, SAMUEL CE, SAFINYA CR: Three-dimensional imaging of lipid gene-carriers: membrane charge density controls universal transfection behavior in lamellar cationic liposome-DNA complexes. Biophys. J. (2003) 84:3307-3316. The original publication on the relevance of membrane charge density and the activated fusion model for lamellar complexes.
-
(2003)
Biophys. J.
, vol.84
, pp. 3307-3316
-
-
Lin, A.J.1
Slack, N.L.2
Ahmad, A.3
George, C.X.4
Samuel, C.E.5
Safinya, C.R.6
-
32
-
-
0034126055
-
Structure-function studies of lipid-DNA nonviral gene delivery systems
-
LIN AJ, SLACK NL, AHMAD A et al.: Structure-function studies of lipid-DNA nonviral gene delivery systems. J. Drug Targeting (2000) 8:13-27.
-
(2000)
J. Drug Targeting
, vol.8
, pp. 13-27
-
-
Lin, A.J.1
Slack, N.L.2
Ahmad, A.3
-
33
-
-
0037038309
-
Efficient synthesis and cell-transfection properties of a new multivalent cationic lipid for nonviral gene delivery
-
EWERT K, AHMAD A, EVANS HM, SCHMIDT HW, SAFINYA CR: Efficient synthesis and cell-transfection properties of a new multivalent cationic lipid for nonviral gene delivery. J. Med. Chem. (2002) 45:5023-5029.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 5023-5029
-
-
Ewert, K.1
Ahmad, A.2
Evans, H.M.3
Schmidt, H.W.4
Safinya, C.R.5
-
34
-
-
0011088157
-
Cationic lipid-DNA complexes for gene delivery: Structure-function correlations
-
Mahato RI, Kim SW (Eds), Taylor & Francis, London, UK
-
SAFINYA CR, SLACK N, LIN A, KOLTOVER I: Cationic lipid-DNA complexes for gene delivery: structure-function correlations. In: Pharmaceutical Perspectives of Nucleic Acid-Based Therapeutics. Mahato RI, Kim SW (Eds), Taylor & Francis, London, UK (2002):190-209.
-
(2002)
Pharmaceutical Perspectives of Nucleic Acid-Based Therapeutics
, pp. 190-209
-
-
Safinya, C.R.1
Slack, N.2
Lin, A.3
Koltover, I.4
-
35
-
-
12244297906
-
Self assembled strutures of lipid-dna nonviral gene delivery systems from synchrotron x-ray diffraction
-
Huang L, Hung M-C, Wagner E (Eds), Academic Press, San Diego, USA
-
SAFINYA CR, KOLTOVER I: Self assembled strutures of lipid-dna nonviral gene delivery systems from synchrotron x-ray diffraction. In: Non-Viral Vectors for Gene Therapy. Huang L, Hung M-C, Wagner E (Eds), Academic Press, San Diego, USA (1999):92-117.
-
(1999)
Non-Viral Vectors for Gene Therapy
, pp. 92-117
-
-
Safinya, C.R.1
Koltover, I.2
-
36
-
-
0030766190
-
Phase I trial of recombinant human interleukin-1-beta (rhIL-1-beta), carboplatin, and etoposide in patients with solid cancers: Southwest Oncology Group Study 8940
-
RINEHART J, HERSH E, ISSELL B, TRIOZZI P, BUHLES W, NEIDHART J: Phase I trial of recombinant human interleukin-1-beta (rhIL-1-beta), carboplatin, and etoposide in patients with solid cancers: Southwest Oncology Group Study 8940. Cancer Invest. (1997) 15:403-410.
-
(1997)
Cancer Invest.
, vol.15
, pp. 403-410
-
-
Rinehart, J.1
Hersh, E.2
Issell, B.3
Triozzi, P.4
Buhles, W.5
Neidhart, J.6
-
37
-
-
0032017880
-
Transfection of primary tumor cells and tumor cell lines with plasmid DNA/lipid complexes
-
STOPECK AT, HERSH EM, BRAILEY JL, CLARK PR, NORMAN J, PARKER SE: Transfection of primary tumor cells and tumor cell lines with plasmid DNA/lipid complexes. Cancer Gene Ther. (1998) 5:119-126.
-
(1998)
Cancer Gene Ther.
, vol.5
, pp. 119-126
-
-
Stopeck, A.T.1
Hersh, E.M.2
Brailey, J.L.3
Clark, P.R.4
Norman, J.5
Parker, S.E.6
-
38
-
-
11644276439
-
Limiting laws and counterion condensation in polyelectrolyte solutions. I. Colligative properties
-
MANNING GS: Limiting laws and counterion condensation in polyelectrolyte solutions. I. Colligative properties. J. Chem. Phys. (1978) 51:924-933.
-
(1978)
J. Chem. Phys.
, vol.51
, pp. 924-933
-
-
Manning, G.S.1
-
39
-
-
84990422191
-
Distribution of counterions around a cylindrical polyelectrolyte and Manning's condensation theory
-
LE BRET M, ZIMM BH: Distribution of counterions around a cylindrical polyelectrolyte and Manning's condensation theory. Biopolymers (1984) 23:287-312.
-
(1984)
Biopolymers
, vol.23
, pp. 287-312
-
-
Le Bret, M.1
Zimm, B.H.2
-
40
-
-
0031807139
-
Structure, stability, and thermodynamics of lamellar DNA-lipid complexes
-
HARRIES D, MAY S, GELBART WM, BEN-SHAUL A: Structure, stability, and thermodynamics of lamellar DNA-lipid complexes. Biophys. J. (1998) 75:159-173.
-
(1998)
Biophys. J.
, vol.75
, pp. 159-173
-
-
Harries, D.1
May, S.2
Gelbart, W.M.3
Ben-Shaul, A.4
-
41
-
-
1642544672
-
Modeling of cationic lipid-DNA complexes
-
MAY S, BEN-SHAUL A: Modeling of cationic lipid-DNA complexes. Curr. Med. Chem. (2004) 11:151-167. A recent review of theoretical work on CL-DNA complexes.
-
(2004)
Curr. Med. Chem.
, vol.11
, pp. 151-167
-
-
May, S.1
Ben-Shaul, A.2
-
42
-
-
0029981092
-
Evidence for the role of proteoglycans in cation-mediated gene transfer
-
MISLICK KA, BALDESCHWIELER JD: Evidence for the role of proteoglycans in cation-mediated gene transfer. Proc. Natl. Acad. Sci. USA (1996) 93:12349-12354.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 12349-12354
-
-
Mislick, K.A.1
Baldeschwieler, J.D.2
-
43
-
-
0032475867
-
Proteoglycans mediate cationic liposome-DNA complex-based gene delivery in vitro and in vivo
-
MOUNKES LC, ZHONG W, CIPRESPALACIN G, HEATH TD, DEBS RJ: Proteoglycans mediate cationic liposome-DNA complex-based gene delivery in vitro and in vivo. J. Biol. Chem. (1998) 273:26164-26170.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 26164-26170
-
-
Mounkes, L.C.1
Zhong, W.2
Ciprespalacin, G.3
Heath, T.D.4
Debs, R.J.5
-
44
-
-
3042857264
-
A model for non-viral gene delivery: Through syndecan adhesion molecules and powered by actin
-
KOPATZ I, REMY J-S, BEHR J-P: A model for non-viral gene delivery: through syndecan adhesion molecules and powered by actin. J. Gene Med. (2004) 6:769-776.
-
(2004)
J. Gene Med.
, vol.6
, pp. 769-776
-
-
Kopatz, I.1
Remy, J.-S.2
Behr, J.-P.3
-
45
-
-
0031642993
-
Electrostatics of DNA cationic lipid complexes: Isoelectric instability
-
BRUINSMA R: Electrostatics of DNA cationic lipid complexes: isoelectric instability. Eur. Phys. J. B (1998) 4:75-88.
-
(1998)
Eur. Phys. J. B
, vol.4
, pp. 75-88
-
-
Bruinsma, R.1
-
47
-
-
0026253815
-
Condensation of DNA by multivalent cations: Considerations on mechanism
-
BLOOMFIELD VA: Condensation of DNA by multivalent cations: considerations on mechanism. Biopolymers (1991) 31:1471-1481.
-
(1991)
Biopolymers
, vol.31
, pp. 1471-1481
-
-
Bloomfield, V.A.1
-
48
-
-
3242746274
-
Physicochemical optimization of plasmid delivery by cationic lipids
-
TRANCHANT I, THOMPSON B, NICOLAZZI C, MIGNET N, SCHERMAN D: Physicochemical optimization of plasmid delivery by cationic lipids. J. Gene Med. (2004) 6:S24-S35. A good and recent review emphasising properties of lipid gene vectors beyond their chemical structure.
-
(2004)
J. Gene Med.
, vol.6
-
-
Tranchant, I.1
Thompson, B.2
Nicolazzi, C.3
Mignet, N.4
Scherman, D.5
-
50
-
-
0029067792
-
The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer
-
FARHOOD H, SERBINA N, HUANG L: The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. Biochim. Biophys. Acta (1995) 1235:289-295.
-
(1995)
Biochim. Biophys. Acta
, vol.1235
, pp. 289-295
-
-
Farhood, H.1
Serbina, N.2
Huang, L.3
-
51
-
-
0344707080
-
The role of helper lipids in cationic liposome-mediated gene transfer
-
HUI S, LANGNER M, ZHAO Y, ROSS P, HURLEY E, CHAN K: The role of helper lipids in cationic liposome-mediated gene transfer. Biophys. J. (1996) 71:590-599.
-
(1996)
Biophys. J.
, vol.71
, pp. 590-599
-
-
Hui, S.1
Langner, M.2
Zhao, Y.3
Ross, P.4
Hurley, E.5
Chan, K.6
-
52
-
-
0024291641
-
X-ray-diffraction study of the polymorphic behavior of N-methylated dioleoylphosphatidylethanolamine
-
GRUNER SM, TATE MW, KIRK GL et al.: X-ray-diffraction study of the polymorphic behavior of N-methylated dioleoylphosphatidylethanolamine. Biochemistry (1988) 27:2853-2866.
-
(1988)
Biochemistry
, vol.27
, pp. 2853-2866
-
-
Gruner, S.M.1
Tate, M.W.2
Kirk, G.L.3
-
53
-
-
0031824356
-
Structure and interactions of fully hydrated dioleoylphosphatidylcholine bilayers
-
TRISTRAM-NAGLE S, PETRACHE HI, NAGLE JF: Structure and interactions of fully hydrated dioleoylphosphatidylcholine bilayers. Biophys. J. (1998) 75:917-925.
-
(1998)
Biophys. J.
, vol.75
, pp. 917-925
-
-
Tristram-Nagle, S.1
Petrache, H.I.2
Nagle, J.F.3
-
54
-
-
0029019120
-
Fusion of cationic liposomes with mammalian cells occurs after endocytosis
-
WROBEL I, COLLINS D: Fusion of cationic liposomes with mammalian cells occurs after endocytosis. Biochim. Biophys. Acta (1995) 1235:296-304.
-
(1995)
Biochim. Biophys. Acta
, vol.1235
, pp. 296-304
-
-
Wrobel, I.1
Collins, D.2
-
55
-
-
0025052479
-
Particulate systems and polymers for in vitro and in vivo delivery of polynucleotides
-
FELGNER PL: Particulate systems and polymers for in vitro and in vivo delivery of polynucleotides. Adv. Drug Deliv. Rev. (1990) 5:163-187.
-
(1990)
Adv. Drug Deliv. Rev.
, vol.5
, pp. 163-187
-
-
Felgner, P.L.1
-
56
-
-
0033136231
-
Synthesis of novel cationic poly(ethylene glycol) containing lipids
-
SCHULZE U, SCHMIDT HW, SAFINYA CR: Synthesis of novel cationic poly(ethylene glycol) containing lipids. Bioconjug. Chem. (1999) 10:548-552.
-
(1999)
Bioconjug. Chem.
, vol.10
, pp. 548-552
-
-
Schulze, U.1
Schmidt, H.W.2
Safinya, C.R.3
-
57
-
-
1642503835
-
Cationic lipid-DNA complexes for gene therapy: Understanding the relationship between complex structure and gene delivery pathways at the molecular level
-
EWERT K, SLACK NL, AHMAD A et al.: Cationic lipid-DNA complexes for gene therapy: understanding the relationship between complex structure and gene delivery pathways at the molecular level. Curr. Med. Chem. (2004) 11:133-149.
-
(2004)
Curr. Med. Chem.
, vol.11
, pp. 133-149
-
-
Ewert, K.1
Slack, N.L.2
Ahmad, A.3
-
58
-
-
12244291636
-
New multivalent lipids reveal bell curve for transfection efficiency versus membrane charge density: Nonviral lipid-DNA complexes for gene delivery
-
In Press
-
AHMAD A, EVANS H, EWERT K, GEORGE CX, SAMUEL CE, SAFINYA CR: New multivalent lipids reveal bell curve for transfection efficiency versus membrane charge density: nonviral lipid-DNA complexes for gene delivery. J. Gene Med. (2005) (In Press).
-
(2005)
J. Gene Med.
-
-
Ahmad, A.1
Evans, H.2
Ewert, K.3
George, C.X.4
Samuel, C.E.5
Safinya, C.R.6
-
59
-
-
0025134135
-
Structure of the inverted hexagonal (HII) phase, and non-lamellar phase transitions of lipids
-
SEDDON JM: Structure of the inverted hexagonal (HII) phase, and non-lamellar phase transitions of lipids. Biochim. Biophys. Acta (1990) 1031:1-69.
-
(1990)
Biochim. Biophys. Acta
, vol.1031
, pp. 1-69
-
-
Seddon, J.M.1
-
60
-
-
0018786933
-
Temperature and compositional dependence of the structure of hydrated dimyristoyl lecithin
-
JANIAK MJ, SMALL DM, SHIPLEY GG: Temperature and compositional dependence of the structure of hydrated dimyristoyl lecithin. J. Biol. Chem. (1979) 254:6068-6078.
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 6068-6078
-
-
Janiak, M.J.1
Small, D.M.2
Shipley, G.G.3
-
61
-
-
0001603395
-
Fluctuations and phase behavior of passages in a stack of fluid membranes
-
GOMPPER G, GOOS J: Fluctuations and phase behavior of passages in a stack of fluid membranes. J. Phys. II (France) (1995) 5:621-634.
-
(1995)
J. Phys. II (France)
, vol.5
, pp. 621-634
-
-
Gompper, G.1
Goos, J.2
-
62
-
-
0029789793
-
Activation of the complement system by synthetic dna complexes: A potential barrier for intravenous gene delivery
-
PLANK C, MECHTLER K, SZOKA FC, WAGNER E: Activation of the complement system by synthetic dna complexes: a potential barrier for intravenous gene delivery. Hum. Gene Ther. (1996) 7:1437-1446. An important paper on obstacles to gene delivery in vivo and a possible way to overcome them.
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 1437-1446
-
-
Plank, C.1
Mechtler, K.2
Szoka, F.C.3
Wagner, E.4
-
64
-
-
0032530812
-
Inhibition of liposome-induced complement activation by incorporated poly(ethylene glycol) lipids
-
BRADLEY AJ, DEVINE DV, ANSELL SM, JANZEN J, BROOKS DE: Inhibition of liposome-induced complement activation by incorporated poly(ethylene glycol) lipids. Arch. Biochem. Biophys. (1998) 357:185-194.
-
(1998)
Arch. Biochem. Biophys.
, vol.357
, pp. 185-194
-
-
Bradley, A.J.1
Devine, D.V.2
Ansell, S.M.3
Janzen, J.4
Brooks, D.E.5
-
65
-
-
0004253585
-
-
CRC Press, Boca Raton, FL, USA
-
Stealth Liposomes. Lasic DD, Martin FJ (Eds), CRC Press, Boca Raton, FL, USA (1995).
-
(1995)
Stealth Liposomes
-
-
Lasic, D.D.1
Martin, F.J.2
-
66
-
-
0029360756
-
Sterically stabilized liposome therapeutics
-
WOODLE MC: Sterically stabilized liposome therapeutics. Adv. Drug Deliv. Rev. (1995) 16:249-265.
-
(1995)
Adv. Drug Deliv. Rev.
, vol.16
, pp. 249-265
-
-
Woodle, M.C.1
-
67
-
-
1142274292
-
Surface functionalized cationic lipid-DNA complexes for gene delivery: PEGylated lamellar complexes exhibit distinct DNA-DNA interaction regimes
-
MARTIN-HERRANZ A, AHMAD A, EVANS HM et al.: Surface functionalized cationic lipid-DNA complexes for gene delivery: PEGylated lamellar complexes exhibit distinct DNA-DNA interaction regimes. Biophys. J. (2004) 86:1160. A thorough study of the effect of incorporating PEG-lipids into CL-DNA complexes.
-
(2004)
Biophys. J.
, vol.86
, pp. 1160
-
-
Martin-Herranz, A.1
Ahmad, A.2
Evans, H.M.3
-
68
-
-
4243266876
-
Self-assembled DNA-cationic-lipid complexes: Two-dimensional smectic ordering, correlations, and interactions
-
SALDITT T, KOLTOVER I, RÄDLER O, SAFINYA CR: Self-assembled DNA-cationic-lipid complexes: two-dimensional smectic ordering, correlations, and interactions. Phys. Rev. E (1998) 58:889-904.
-
(1998)
Phys. Rev. E
, vol.58
, pp. 889-904
-
-
Salditt, T.1
Koltover, I.2
Rädler, O.3
Safinya, C.R.4
-
70
-
-
0026240517
-
Asymptotic-behavior and long-range interactions in aqueous-solutions of poly(ethylene oxide)
-
DEVANAND K, SELSER JC: Asymptotic-behavior and long-range interactions in aqueous-solutions of poly(ethylene oxide). Macromolecules (1991) 24:5943-5947.
-
(1991)
Macromolecules
, vol.24
, pp. 5943-5947
-
-
Devanand, K.1
Selser, J.C.2
-
71
-
-
0030589851
-
Lamellar biogels: Fluid-membrane-based hydrogels containing polymer lipids
-
WARRINER HE, IDZIAK SH, SLACK NL, DAVIDSON P, SAFINYA CR: Lamellar biogels: Fluid-membrane-based hydrogels containing polymer lipids. Science (1996) 271:969-973.
-
(1996)
Science
, vol.271
, pp. 969-973
-
-
Warriner, H.E.1
Idziak, S.H.2
Slack, N.L.3
Davidson, P.4
Safinya, C.R.5
-
72
-
-
0033818099
-
Use of poly(ethylene glycol)-lipid conjugates to regulate the surface attributes and transfection activity of lipid-DNA particles
-
HARVIE P, WONG FM, BALLY MB: Use of poly(ethylene glycol)-lipid conjugates to regulate the surface attributes and transfection activity of lipid-DNA particles. J. Pharm. Sci. (2000) 89:652-663.
-
(2000)
J. Pharm. Sci.
, vol.89
, pp. 652-663
-
-
Harvie, P.1
Wong, F.M.2
Bally, M.B.3
-
73
-
-
0011797006
-
Sterically stabilized BGTC-based lipoplexes: Structural features and gene transfection into the mouse airways in vivo
-
PITARD B, OUDRHIRI N, LAMBERT O et al.: Sterically stabilized BGTC-based lipoplexes: structural features and gene transfection into the mouse airways in vivo. J. Gene Med. (2001) 3:478-487.
-
(2001)
J. Gene Med.
, vol.3
, pp. 478-487
-
-
Pitard, B.1
Oudrhiri, N.2
Lambert, O.3
-
74
-
-
0032991616
-
Stabilized plasmid-lipid particles: Construction and characterization
-
WHEELER JJ, PALMER L, OSSANLOU M et al.: Stabilized plasmid-lipid particles: construction and characterization. Gene Ther. (1999) 6:271-281. An alternative method of preparing lipid-DNA assemblies, resulting in well defined, sterically stabilised particles.
-
(1999)
Gene Ther.
, vol.6
, pp. 271-281
-
-
Wheeler, J.J.1
Palmer, L.2
Ossanlou, M.3
-
75
-
-
0028222291
-
Long-circulating (sterically stabilized) liposomes for targeted drug-delivery
-
ALLEN TM: Long-circulating (sterically stabilized) liposomes for targeted drug-delivery. Trends Pharmacol. Sci. (1994) 15:215-220.
-
(1994)
Trends Pharmacol. Sci.
, vol.15
, pp. 215-220
-
-
Allen, T.M.1
-
76
-
-
3042852733
-
Intracytoplasmatic delivery of anionic proteins
-
DALKARA D, ZUBER G, BEHR J-P: Intracytoplasmatic delivery of anionic proteins. Mol. Ther. (2004) 9:964-969.
-
(2004)
Mol. Ther.
, vol.9
, pp. 964-969
-
-
Dalkara, D.1
Zuber, G.2
Behr, J.-P.3
-
77
-
-
0034639426
-
Structure of complexes of cationic lipids and poly(glutamic acid) polypeptides: A pinched lamellar phase
-
SUBRAMANIAN G, HJELM RP, DEMING TJ, SMITH GS, LI Y, SAFINYA CR: Structure of complexes of cationic lipids and poly(glutamic acid) polypeptides: a pinched lamellar phase. J. Am. Chem. Soc. (2000) 122:26-34.
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 26-34
-
-
Subramanian, G.1
Hjelm, R.P.2
Deming, T.J.3
Smith, G.S.4
Li, Y.5
Safinya, C.R.6
-
78
-
-
0034674445
-
Hierarchical self-assembly of f-actin and cationic lipid complexes: Stacked three-layer tubule networks
-
WONG GC, TANG JX, LIN A, LI Y, JANMEY PA, SAFINYA CR: Hierarchical self-assembly of f-actin and cationic lipid complexes: stacked three-layer tubule networks. Science (2000) 288:2035-2039.
-
(2000)
Science
, vol.288
, pp. 2035-2039
-
-
Wong, G.C.1
Tang, J.X.2
Lin, A.3
Li, Y.4
Janmey, P.A.5
Safinya, C.R.6
-
79
-
-
0036853181
-
An angiogenic, endothelial-cell-targeted polymeric gene carrier
-
SUH W, HAN SO, YU L, KIM SW: An angiogenic, endothelial-cell-targeted polymeric gene carrier. Mol. Ther. (2002) 6:664-672.
-
(2002)
Mol. Ther.
, vol.6
, pp. 664-672
-
-
Suh, W.1
Han, S.O.2
Yu, L.3
Kim, S.W.4
-
80
-
-
0035816174
-
Sterically stabilized polyplex: Ligand-mediated activity
-
WOODLE MC, SCARIA P, GANESH S et al.: Sterically stabilized polyplex: ligand-mediated activity. J. Control. Release (2001) 74:309-311.
-
(2001)
J. Control. Release
, vol.74
, pp. 309-311
-
-
Woodle, M.C.1
Scaria, P.2
Ganesh, S.3
-
81
-
-
1142267906
-
Peptide-based gene delivery systems
-
Mahato RI, SW Kim (Eds), Taylor & Francis, London, UK
-
MIDOUX P, PICHON C: Peptide-based gene delivery systems. In: Pharmaceutical Perspectives of Nucleic Acid-Based Therapeutics. Mahato RI, SW Kim (Eds), Taylor & Francis, London, UK (2002):334-366.
-
(2002)
Pharmaceutical Perspectives of Nucleic Acid-Based Therapeutics
, pp. 334-366
-
-
Midoux, P.1
Pichon, C.2
-
82
-
-
0021716406
-
A short amino acid sequence able to specify nuclear localization
-
KALDERON D, ROBERTS BL, RICHARDSON WD, SMITH AE: A short amino acid sequence able to specify nuclear localization. Cell (1984) 39:499-509.
-
(1984)
Cell
, vol.39
, pp. 499-509
-
-
Kalderon, D.1
Roberts, B.L.2
Richardson, W.D.3
Smith, A.E.4
-
83
-
-
0031869439
-
Signals mediating nuclear targeting and their regulation: Application in drug delivery
-
JANS DA, CHAN CK, HÜBNER S: Signals mediating nuclear targeting and their regulation: application in drug delivery. Med. Res. Rev. (1998) 18:189-223.
-
(1998)
Med. Res. Rev.
, vol.18
, pp. 189-223
-
-
Jans, D.A.1
Chan, C.K.2
Hübner, S.3
-
84
-
-
0033038501
-
Cationic lipid-mediated transfection of cells in culture requires mitotic activity
-
MORTIMER I, TAM P, MACLACHLAN I, GRAHAM RW, SARAVOLAC EG, JOSHI PB: Cationic lipid-mediated transfection of cells in culture requires mitotic activity. Gene Ther. (1999) 6:403-411.
-
(1999)
Gene Ther.
, vol.6
, pp. 403-411
-
-
Mortimer, I.1
Tam, P.2
Maclachlan, I.3
Graham, R.W.4
Saravolac, E.G.5
Joshi, P.B.6
-
85
-
-
0036190843
-
Utilization of synthetic peptides containing nuclear localization signals for nonviral gene transfer systems
-
CARTIER R, RESZKA R: Utilization of synthetic peptides containing nuclear localization signals for nonviral gene transfer systems. Gene Ther. (2002) 9:157-167. A good, critical review of work that employed NLS peptides for non-viral vectors.
-
(2002)
Gene Ther.
, vol.9
, pp. 157-167
-
-
Cartier, R.1
Reszka, R.2
-
86
-
-
0347926089
-
NLS bioconjugates for targeting therapeutic genes to the nucleus
-
ESCRIOU V, CARRIERE M, SCHERMAN D, WILS P: NLS bioconjugates for targeting therapeutic genes to the nucleus. Adv. Drug Deliv. Rev. (2003) 55:295-306. Another, slightly more recent, critical review of work employing NLS peptides.
-
(2003)
Adv. Drug Deliv. Rev.
, vol.55
, pp. 295-306
-
-
Escriou, V.1
Carriere, M.2
Scherman, D.3
Wils, P.4
-
87
-
-
0038039166
-
Improvement of exogenous DNA nuclear importation by nuclear localization signal-bearing vectors: A promising way for non-viral gene therapy?
-
HEBERT E: Improvement of exogenous DNA nuclear importation by nuclear localization signal-bearing vectors: a promising way for non-viral gene therapy? Biol. Cell (2003) 95:59-68.
-
(2003)
Biol. Cell
, vol.95
, pp. 59-68
-
-
Hebert, E.1
-
88
-
-
6144247394
-
Universality in interacting membranes: The effect of cosurfactants on the interfacial rigidity
-
SAFINYA CR, SIROTA EB, ROUX D, SMITH GS: Universality in interacting membranes: the effect of cosurfactants on the interfacial rigidity. Phys. Rev. Lett. (1989) 62:1134-1137.
-
(1989)
Phys. Rev. Lett.
, vol.62
, pp. 1134-1137
-
-
Safinya, C.R.1
Sirota, E.B.2
Roux, D.3
Smith, G.S.4
-
89
-
-
33751554785
-
Chain packing statistics and thermodynamics of amphilphile monolayers
-
SZLEIFER I, BEN-SHAUL A, GELBART WM: Chain packing statistics and thermodynamics of amphilphile monolayers. J. Phys. Chem. (1990) 94:5081-5089.
-
(1990)
J. Phys. Chem.
, vol.94
, pp. 5081-5089
-
-
Szleifer, I.1
Ben-Shaul, A.2
Gelbart, W.M.3
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