Action potential initiation and propagation in rat neocortical pyramidal neurons

Journal of Physiology

Volumn 505, Issue 3, 1997, Pages 617-632

  Stuart, Greg ^a,b   Schiller, Jackie ^a   Sakmann, Bert ^a  

^a MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

^b Biology and Environment   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM; TETRODOTOXIN;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; HYPERPOLARIZATION; NEOCORTEX; NERVE FIBER REGENERATION; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SYNAPSE; VOLTAGE CLAMP; ANIMAL TISSUE; CALCIUM ELECTROGENESIS; CALCIUM TRANSPORT; CELL BODY; DENDRITE; ELECTRIC POTENTIAL; EVOKED RESPONSE; EXTRACELLULAR SPACE; LATENT PERIOD; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE CELL STIMULATION; NERVE CONDUCTION VELOCITY; REGENERATIVE POTENTIAL; SOMATIC ACTION POTENTIAL;

ACTION POTENTIALS; ANIMALS; AXONS; DENDRITES; ELECTRIC CONDUCTIVITY; EXCITATORY POSTSYNAPTIC POTENTIALS; NEOCORTEX; PATCH-CLAMP TECHNIQUES; PYRAMIDAL CELLS; RATS; RATS, WISTAR; SYNAPSES;

EID: 0031574080     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1997.617ba.x     Document Type: Article

References (37)

1. AMITAI, Y., FRIEDMAN, B., CONNORS, B. W. & GUTNICK, M. J. (1993). Regenerative activity in apical dendrites of pyramidal cells in neocortex. Cerebral Cortex 3, 26-38.
2. BUHL, E. H., HALASY, K. & SOMOGYI, P. (1994). Diverse sources of hippocampal unitary inhibitory postsynaptic potentials and the number of synaptic release sites. Nature 68, 823-882.
3. + current contributes to loss of action potential amplitude in dendritic spike trains. Society for Neuroscience Abstracts 22, 791.
4. + channel densities in the initial segment and soma of subicular pyramidal neurons. Journal of Neuroscience 16, 6676-6687.
5. COOMBS, J. S., CURTIS, D. R. & ECCLES, J. C. (1957). The interpretation of spike potentials of motoneurones. Journal of Physiology 139, 198-231.
6. CUMMINS, T. R., XIA, Y. & HADDAD, G. G. (1994). Functional properties of rat and human neocortical voltage-sensitive sodium currents. Journal of Neurophysiology 71, 1052-1064.
7. DESCHENES, M. (1981). Dendritic spikes induced in fast pyramidal tract neurons by thalamic stimulation. Experimental Brain Research 43, 304-308.
8. ECCLES, J. C. (1964). The Physiology of Synapses. Springer-Verlag, Berlin.
9. ENGEL, A. K., KONIG, P., KREITER, A. K., SCHILLEN, T. B. & SINGER, W. (1992). Temporal coding in the visual cortex: new vistas on integration in the nervous system. Trends in Neurosciences 15, 218-226.
10. GOGAN, P., GUERITAUD, J. P. & TYC-DUMONT, S. (1983). Comparison of antidromic and orthodromic action potentials of identified motor axons in the cat's brain stem. Journal of Physiology 335, 205-220.
11. GOLDSTEIN, S. S. & RALL, W. (1974). Changes of action potential shape and velocity for changing core conductor geometry. Biophysical Journal 14, 731-757.
12. HIRSCH, J. A., ALONSO, J.-M. & REID, R. C. (1995). Visually evoked calcium action potentials in cat striate cortex. Nature 378, 612-616.
13. JACK, J. J. B., NOBLE, D. & TSIEN, R. W. (1983). Electrical Current Flow in Excitable Cells. Oxford University Press, Oxford.
14. JOHNSTON, D., MAGEE, J. C., COLBERT, C. M. & CHRISTIE, R. (1996). Active properties of neuronal dendrites. Annual Review of Neuroscience 19, 165-186.
15. KASPER, E. M., LARKMAN, A. U., LÜBKE, J. & BLAKEMORE, C. (1994). Pyramidal neurons in layer 5 of the rat visual cortex. II. Development of electrophysiological properties. Journal of Comparative Neurology 339, 475-494.
16. KIM, H. G. & CONNORS, B. W. (1993). Apical dendrites of the neocortex: Correlation between sodium- and calcium-dependent spiking and pyramidal cell morphology. Journal of Neuroscience 13, 5301-5311.
17. LORENZON, N. M. & FOEHRING, R. C. (1990). Characterization of pharmacologically identified voltage-gated calcium currents in acutely isolated rat neocortical neurons. II. Postnatal development. Journal of Neurophysiology 73, 1443-1451.
18. MCCORMICK, D. A. & PRINCE, D. A. (1987). Post-natal development of electrophysiological properties of rat cerebral cortical pyramidal neurones. Journal of Physiology 393, 743-762.
19. MACVICAR, B. A. & DUDEK, F. E. (1981). Electrotonic coupling between pyramidal cells: a direct demonstration in rat hippocampal slices. Science 213, 782-785.
20. MAINEN, Z. F., JOERGES, J., HUGUENARD, J. R. & SEJNOWSKI, T. J. (1995). A model of spike initiation in neocortical pyramidal neurons. Neuron 15, 1427-1439.
21. MILES, R., TOTH, K., GULYAS, A. I., HAJOS, N. & FREUND, T. F. (1996). Differences between somatic and dendritic inhibition in the hippocampus. Neuron 16, 815-823.
22. POCKBERGER, H. (1991). Electrophysiological and morphological properties of rat motor cortex neurons in vivo. Brain Research 539, 181-190.
23. RALL, W. & SEGEV, I. (1987). Functional possibilities for synapses on dendrites and dendritic spines. In Synoptic Function, ed. EDELMAN, G. M., GALL, W. E. & COWAN, W. M., pp. 605-636. John Wiley & Sons, New York.
24. REGEHR, W. G. & ARMSTRONG, C. M. (1994). Dendritic function. Where does it all begin? Current Biology 4, 436-439.
25. REGEHR, W., KEHOE, J., ASCHER, P. & ARMSTRONG, C. (1993). Synaptically triggered action potentials in dendrites. Neuron 11, 145-151.
26. SCHILLER, J., HELMCHEN, F. & SAKMANN, B. (1995). Spatial profile of dendritic calcium transients evoked by action potentials in rat neocortical pyramidal neurons. Journal of Physiology 487, 583-600.
27. SCHILLER, J., SCHILLER, Y., STUART, G. & SAKMANN, B. (1997). Calcium action potentials restricted to distal apical dendrites of rat neocortical pyramidal neurons. Journal of Physiology 505, 605-616.
28. SOFTKY, W. (1994). Sub-millisecond coincidence detection in active dendritic trees. Neuroscience 58, 13-41.
29. SPENCER, W. A. & KANDEL, E. R. (1961). Electrophysiology of hippocampal neurons. IV. Fast prepotentials. Journal of Neurophysiology 24, 272-285.
30. SPRUSTON, N., SCHILLER, Y., STUART, G. & SAKMANN, B. (1995). Activity-dependent action potential invasion and calcium influx into hippocampal CA1 dendrites. Science 268, 297-300.
31. STUART, G. & HÄUSSER, M. (1994). Initiation and spread of sodium action potentials in cerebellar purkinje cells. Neuron 13, 703-712.
32. STUART, G. & SAKMANN, B. (1995). Amplification of EPSPs by axosomatic sodium channels in neocortical pyramidal neurons. Neuron 15, 1065-1077.
33. STUART, G. & SAKMANN, B. (1996). Action potential initiation in neocortical pyramidal neurons - revisited. Society for Neuroscience Abstract 22, 794.
34. STUART, G., SPRUSTON, N., SAKMANN, B. & HÄUSSER, M. (1997). Action potential initiation and backpropagation in neurons of the mammalian central nervous system. Trends in Neurosciences 20, 125-131.
35. STUART, G. J. & SAKMANN, B. (1994). Active propagation of somatic action potentials into neocortical pyramidal cell dendrites. Nature 367, 69-72.
36. TURNER, R. W., MEYERS, D. E., RICHARDSON, T. L. & BARKER, J. L. (1991). The site for initiation of action potential discharge over the somatodendritic axis of rat hippocampal CA1 pyramidal neurons. Journal of Neuroscience 11, 2270-2280.
37. VALIANTE, T. A., VELAZQUEZ, J. L. P., JAHROMI, S. S. & CARLEN, P. L. (1995) Coupling potentials in CA1 neurons during calcium-free-induced field burst activity. Journal of Neuroscience 15, 6946-6956.