메뉴 건너뛰기




Volumn 136, Issue 5, 2009, Pages 1721-1731

Amelioration of Colitis by Genetically Engineered Murine Regulatory T Cells Redirected by Antigen-Specific Chimeric Receptor

Author keywords

[No Author keywords available]

Indexed keywords

PICRIC ACID; RECOMBINANT RECEPTOR; RETROVIRUS VECTOR; TRANSCRIPTION FACTOR FOXP3; TRIPARTITE CHIMERIC RECEPTOR; UNCLASSIFIED DRUG;

EID: 65249120858     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2009.01.049     Document Type: Article
Times cited : (139)

References (46)
  • 1
    • 0032538819 scopus 로고    scopus 로고
    • Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor β (TGF-β) production by murine CD4(+) T cells
    • Chen W., Jin W., and Wahl S.M. Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor β (TGF-β) production by murine CD4(+) T cells. J Exp Med 188 (1998) 1849-1857
    • (1998) J Exp Med , vol.188 , pp. 1849-1857
    • Chen, W.1    Jin, W.2    Wahl, S.M.3
  • 2
    • 33645102841 scopus 로고    scopus 로고
    • An intersection between the self-reactive regulatory and nonregulatory T-cell receptor repertoires
    • Hsieh C.S., Zheng Y., Liang Y., et al. An intersection between the self-reactive regulatory and nonregulatory T-cell receptor repertoires. Nat Immunol 7 (2006) 401-410
    • (2006) Nat Immunol , vol.7 , pp. 401-410
    • Hsieh, C.S.1    Zheng, Y.2    Liang, Y.3
  • 3
    • 1642331576 scopus 로고    scopus 로고
    • Immune regulation by self-reactive T cells is antigen specific
    • Tanchot C., Vasseur F., Pontoux C., et al. Immune regulation by self-reactive T cells is antigen specific. J Immunol 172 (2004) 4285-4291
    • (2004) J Immunol , vol.172 , pp. 4285-4291
    • Tanchot, C.1    Vasseur, F.2    Pontoux, C.3
  • 4
    • 0036597371 scopus 로고    scopus 로고
    • CD4+ CD25+ suppressor T cells: more questions than answers
    • Shevach E.M. CD4+ CD25+ suppressor T cells: more questions than answers. Nat Rev Immunol 2 (2002) 389-400
    • (2002) Nat Rev Immunol , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 5
    • 0029788211 scopus 로고    scopus 로고
    • Autoimmune disease as a consequence of developmental abnormality of a T-cell subpopulation
    • Asano M., Toda M., Sakaguchi N., et al. Autoimmune disease as a consequence of developmental abnormality of a T-cell subpopulation. J Exp Med 184 (1996) 387-396
    • (1996) J Exp Med , vol.184 , pp. 387-396
    • Asano, M.1    Toda, M.2    Sakaguchi, N.3
  • 6
    • 20444434616 scopus 로고    scopus 로고
    • Peripheral and intestinal regulatory CD4+ CD25(high) T cells in inflammatory bowel disease
    • Maul J., Loddenkemper C., Mundt P., et al. Peripheral and intestinal regulatory CD4+ CD25(high) T cells in inflammatory bowel disease. Gastroenterology 128 (2005) 1868-1878
    • (2005) Gastroenterology , vol.128 , pp. 1868-1878
    • Maul, J.1    Loddenkemper, C.2    Mundt, P.3
  • 7
    • 0037446531 scopus 로고    scopus 로고
    • Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells
    • Mottet C., Uhlig H.H., and Powrie F. Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells. J Immunol 170 (2003) 3939-3943
    • (2003) J Immunol , vol.170 , pp. 3939-3943
    • Mottet, C.1    Uhlig, H.H.2    Powrie, F.3
  • 8
    • 0037062420 scopus 로고    scopus 로고
    • Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T-cell receptor transgenic mice
    • Hori S., Haury M., Coutinho A., et al. Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T-cell receptor transgenic mice. Proc Natl Acad Sci U S A 99 (2002) 8213-8218
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 8213-8218
    • Hori, S.1    Haury, M.2    Coutinho, A.3
  • 9
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S., Sakaguchi N., Asano M., et al. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 155 (1995) 1151-1164
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3
  • 10
    • 32644459908 scopus 로고    scopus 로고
    • Antigen-specific regulatory T cells-ex vivo expansion and therapeutic potential
    • Masteller E.L., Tang Q., and Bluestone J.A. Antigen-specific regulatory T cells-ex vivo expansion and therapeutic potential. Semin Immunol 18 (2006) 103-110
    • (2006) Semin Immunol , vol.18 , pp. 103-110
    • Masteller, E.L.1    Tang, Q.2    Bluestone, J.A.3
  • 11
    • 23844550915 scopus 로고    scopus 로고
    • IL-10-dependent infectious tolerance after the treatment of experimental allergic encephalomyelitis with redirected CD4+CD25+ T lymphocytes
    • Mekala D.J., Alli R.S., and Geiger T.L. IL-10-dependent infectious tolerance after the treatment of experimental allergic encephalomyelitis with redirected CD4+CD25+ T lymphocytes. Proc Natl Acad Sci U S A 102 (2005) 11817-11822
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 11817-11822
    • Mekala, D.J.1    Alli, R.S.2    Geiger, T.L.3
  • 12
    • 44649157803 scopus 로고    scopus 로고
    • Redirection of regulatory T cells with predetermined specificity for the treatment of experimental colitis in mice
    • Elinav E., Waks T., and Eshhar Z. Redirection of regulatory T cells with predetermined specificity for the treatment of experimental colitis in mice. Gastroenterology 134 (2008) 2014-2024
    • (2008) Gastroenterology , vol.134 , pp. 2014-2024
    • Elinav, E.1    Waks, T.2    Eshhar, Z.3
  • 13
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot J.D., Gavin M.A., and Rudensky A.Y. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 4 (2003) 330-336
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 14
    • 27644503683 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T-cell lines from human cord blood have functional and molecular properties of T-cell anergy
    • Li L., Godfrey W.R., Porter S.B., et al. CD4+CD25+ regulatory T-cell lines from human cord blood have functional and molecular properties of T-cell anergy. Blood 106 (2005) 3068-3073
    • (2005) Blood , vol.106 , pp. 3068-3073
    • Li, L.1    Godfrey, W.R.2    Porter, S.B.3
  • 15
    • 17044378252 scopus 로고    scopus 로고
    • Redirected primary T cells harboring a chimeric receptor require costimulation for their antigen-specific activation
    • Friedmann-Morvinski D., Bendavid A., Waks T., et al. Redirected primary T cells harboring a chimeric receptor require costimulation for their antigen-specific activation. Blood 105 (2005) 3087-3093
    • (2005) Blood , vol.105 , pp. 3087-3093
    • Friedmann-Morvinski, D.1    Bendavid, A.2    Waks, T.3
  • 16
    • 0027471898 scopus 로고
    • Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the γ or ξ subunits of the immunoglobulin and T-cell receptors
    • Eshhar Z., Waks T., Gross G., et al. Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the γ or ξ subunits of the immunoglobulin and T-cell receptors. Proc Natl Acad Sci U S A 90 (1993) 720-724
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 720-724
    • Eshhar, Z.1    Waks, T.2    Gross, G.3
  • 17
    • 21044456328 scopus 로고    scopus 로고
    • In vivo imaging of colitis and colon cancer development in mice using high-resolution chromoendoscopy
    • Becker C., Fantini M.C., Wirtz S., et al. In vivo imaging of colitis and colon cancer development in mice using high-resolution chromoendoscopy. Gut 54 (2005) 950-954
    • (2005) Gut , vol.54 , pp. 950-954
    • Becker, C.1    Fantini, M.C.2    Wirtz, S.3
  • 18
    • 15244358572 scopus 로고    scopus 로고
    • Adoptive immunotherapy of prostate cancer bone lesions using redirected effector lymphocytes
    • Pinthus J.H., Waks T., Malina V., et al. Adoptive immunotherapy of prostate cancer bone lesions using redirected effector lymphocytes. J Clin Invest 114 (2004) 1774-1781
    • (2004) J Clin Invest , vol.114 , pp. 1774-1781
    • Pinthus, J.H.1    Waks, T.2    Malina, V.3
  • 19
    • 36248976097 scopus 로고    scopus 로고
    • CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells
    • Pandiyan P., Zheng L., Ishihara S., et al. CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells. Nat Immunol 8 (2007) 1353-1362
    • (2007) Nat Immunol , vol.8 , pp. 1353-1362
    • Pandiyan, P.1    Zheng, L.2    Ishihara, S.3
  • 20
    • 33847727077 scopus 로고    scopus 로고
    • IL-10, regulatory T cells, and Kupffer cells mediate tolerance in Concanavalin A-induced liver injury in mice
    • Erhardt A., Biburger M., Papadopoulos T., et al. IL-10, regulatory T cells, and Kupffer cells mediate tolerance in Concanavalin A-induced liver injury in mice. Hepatology 45 (2007) 475-485
    • (2007) Hepatology , vol.45 , pp. 475-485
    • Erhardt, A.1    Biburger, M.2    Papadopoulos, T.3
  • 21
    • 38849199737 scopus 로고    scopus 로고
    • Effective proliferation of human regulatory T cells requires a strong costimulatory CD28 signal that cannot be substituted by IL-2
    • Hombach A.A., Kofler D., Hombach A., et al. Effective proliferation of human regulatory T cells requires a strong costimulatory CD28 signal that cannot be substituted by IL-2. J Immunol 179 (2007) 7924-7931
    • (2007) J Immunol , vol.179 , pp. 7924-7931
    • Hombach, A.A.1    Kofler, D.2    Hombach, A.3
  • 22
    • 34250018776 scopus 로고    scopus 로고
    • Generation and maturation of bone marrow-derived DCs under serum-free conditions
    • Kim S.J., and Diamond B. Generation and maturation of bone marrow-derived DCs under serum-free conditions. J Immunol Methods 323 (2007) 101-108
    • (2007) J Immunol Methods , vol.323 , pp. 101-108
    • Kim, S.J.1    Diamond, B.2
  • 23
    • 56649095904 scopus 로고    scopus 로고
    • IL-2 family of cytokines in T regulatory cell development and homeostasis
    • Malek T.R., Yu A., Zhu L., et al. IL-2 family of cytokines in T regulatory cell development and homeostasis. J Clin Immunol 28 (2008) 635-639
    • (2008) J Clin Immunol , vol.28 , pp. 635-639
    • Malek, T.R.1    Yu, A.2    Zhu, L.3
  • 24
    • 0033082138 scopus 로고    scopus 로고
    • Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells
    • Moriggl R., Topham D.J., Teglund S., et al. Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells. Immunity 10 (1999) 249-259
    • (1999) Immunity , vol.10 , pp. 249-259
    • Moriggl, R.1    Topham, D.J.2    Teglund, S.3
  • 25
    • 0037100384 scopus 로고    scopus 로고
    • Modulation of Fas-dependent apoptosis: a dynamic process controlling both the persistence and death of CD4 regulatory T cells and effector T cells
    • Banz A., Pontoux C., and Papiernik M. Modulation of Fas-dependent apoptosis: a dynamic process controlling both the persistence and death of CD4 regulatory T cells and effector T cells. J Immunol 169 (2002) 750-757
    • (2002) J Immunol , vol.169 , pp. 750-757
    • Banz, A.1    Pontoux, C.2    Papiernik, M.3
  • 26
    • 33645786794 scopus 로고    scopus 로고
    • Adaptive islet-specific regulatory CD4 T cells control autoimmune diabetes and mediate the disappearance of pathogenic Th1 cells in vivo
    • Weber S.E., Harbertson J., Godebu E., et al. Adaptive islet-specific regulatory CD4 T cells control autoimmune diabetes and mediate the disappearance of pathogenic Th1 cells in vivo. J Immunol 176 (2006) 4730-4739
    • (2006) J Immunol , vol.176 , pp. 4730-4739
    • Weber, S.E.1    Harbertson, J.2    Godebu, E.3
  • 27
    • 5644263642 scopus 로고    scopus 로고
    • Role of LAG-3 in regulatory T cells
    • Huang C.T., Workman C.J., Flies D., et al. Role of LAG-3 in regulatory T cells. Immunity 21 (2004) 503-513
    • (2004) Immunity , vol.21 , pp. 503-513
    • Huang, C.T.1    Workman, C.J.2    Flies, D.3
  • 28
    • 13544271161 scopus 로고    scopus 로고
    • Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism
    • Gondek D.C., Lu L.F., Quezada S.A., et al. Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism. J Immunol 174 (2005) 1783-1786
    • (2005) J Immunol , vol.174 , pp. 1783-1786
    • Gondek, D.C.1    Lu, L.F.2    Quezada, S.A.3
  • 29
    • 0036498794 scopus 로고    scopus 로고
    • Administration of an antigen at a high dose generates regulatory CD4+ T cells expressing CD95 ligand and secreting IL-4 in the liver
    • Watanabe T., Yoshida M., Shirai Y., et al. Administration of an antigen at a high dose generates regulatory CD4+ T cells expressing CD95 ligand and secreting IL-4 in the liver. J Immunol 168 (2002) 2188-2199
    • (2002) J Immunol , vol.168 , pp. 2188-2199
    • Watanabe, T.1    Yoshida, M.2    Shirai, Y.3
  • 30
    • 13544277369 scopus 로고    scopus 로고
    • Induction of tolerance using Fas ligand: a double-edged immunomodulator
    • Askenasy N., Yolcu E.S., Yaniv I., et al. Induction of tolerance using Fas ligand: a double-edged immunomodulator. Blood 105 (2005) 1396-1404
    • (2005) Blood , vol.105 , pp. 1396-1404
    • Askenasy, N.1    Yolcu, E.S.2    Yaniv, I.3
  • 31
    • 0033985780 scopus 로고    scopus 로고
    • Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific
    • Thornton A.M., and Shevach E.M. Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J Immunol 164 (2000) 183-190
    • (2000) J Immunol , vol.164 , pp. 183-190
    • Thornton, A.M.1    Shevach, E.M.2
  • 32
    • 0035421654 scopus 로고    scopus 로고
    • Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells
    • Piccirillo C.A., and Shevach E.M. Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells. J Immunol 167 (2001) 1137-1140
    • (2001) J Immunol , vol.167 , pp. 1137-1140
    • Piccirillo, C.A.1    Shevach, E.M.2
  • 33
    • 4344657757 scopus 로고    scopus 로고
    • CD4+CD25+ cells controlling a pathogenic CD4 response inhibit cytokine differentiation, CXCR-3 expression, and tissue invasion
    • Sarween N., Chodos A., Raykundalia C., et al. CD4+CD25+ cells controlling a pathogenic CD4 response inhibit cytokine differentiation, CXCR-3 expression, and tissue invasion. J Immunol 173 (2004) 2942-2951
    • (2004) J Immunol , vol.173 , pp. 2942-2951
    • Sarween, N.1    Chodos, A.2    Raykundalia, C.3
  • 34
    • 0033853625 scopus 로고    scopus 로고
    • Naturally anergic and suppressive CD25(+)CD4(+) T cells as a functionally and phenotypically distinct immunoregulatory T-cell subpopulation
    • Kuniyasu Y., Takahashi T., Itoh M., et al. Naturally anergic and suppressive CD25(+)CD4(+) T cells as a functionally and phenotypically distinct immunoregulatory T-cell subpopulation. Int Immunol 12 (2000) 1145-1155
    • (2000) Int Immunol , vol.12 , pp. 1145-1155
    • Kuniyasu, Y.1    Takahashi, T.2    Itoh, M.3
  • 35
    • 10844288839 scopus 로고    scopus 로고
    • Uncoupling of IL-2 signaling from cell cycle progression in naive CD4+ T cells by regulatory CD4+CD25+ T lymphocytes
    • Duthoit C.T., Mekala D.J., Alli R.S., et al. Uncoupling of IL-2 signaling from cell cycle progression in naive CD4+ T cells by regulatory CD4+CD25+ T lymphocytes. J Immunol 174 (2005) 155-163
    • (2005) J Immunol , vol.174 , pp. 155-163
    • Duthoit, C.T.1    Mekala, D.J.2    Alli, R.S.3
  • 36
    • 33745263084 scopus 로고    scopus 로고
    • Defective cell cycle induction by IL-2 in naive T-cells antigen stimulated in the presence of refractory T lymphocytes
    • Inaba H., and Geiger T.L. Defective cell cycle induction by IL-2 in naive T-cells antigen stimulated in the presence of refractory T lymphocytes. Int Immunol 18 (2006) 1043-1054
    • (2006) Int Immunol , vol.18 , pp. 1043-1054
    • Inaba, H.1    Geiger, T.L.2
  • 37
    • 36549030784 scopus 로고    scopus 로고
    • The inhibitory cytokine IL-35 contributes to regulatory T-cell function
    • Collison L.W., Workman C.J., Kuo T.T., et al. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 450 (2007) 566-569
    • (2007) Nature , vol.450 , pp. 566-569
    • Collison, L.W.1    Workman, C.J.2    Kuo, T.T.3
  • 38
    • 33847415066 scopus 로고    scopus 로고
    • Natural regulatory T cells: mechanisms of suppression
    • Miyara M., and Sakaguchi S. Natural regulatory T cells: mechanisms of suppression. Trends Mol Med 13 (2007) 108-116
    • (2007) Trends Mol Med , vol.13 , pp. 108-116
    • Miyara, M.1    Sakaguchi, S.2
  • 39
    • 33847153417 scopus 로고    scopus 로고
    • Foxp3-dependent programme of regulatory T-cell differentiation
    • Gavin M.A., Rasmussen J.P., Fontenot J.D., et al. Foxp3-dependent programme of regulatory T-cell differentiation. Nature 445 (2007) 771-775
    • (2007) Nature , vol.445 , pp. 771-775
    • Gavin, M.A.1    Rasmussen, J.P.2    Fontenot, J.D.3
  • 40
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T-cell development by the transcription factor Foxp3
    • Hori S., Nomura T., and Sakaguchi S. Control of regulatory T-cell development by the transcription factor Foxp3. Science 299 (2003) 1057-1061
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 41
    • 34548132058 scopus 로고    scopus 로고
    • Functional and genomic analyses of FOXP3-transduced Jurkat-T cells as regulatory T (Treg)-like cells
    • Kim J.Y., Kim H.J., Hurt E.M., et al. Functional and genomic analyses of FOXP3-transduced Jurkat-T cells as regulatory T (Treg)-like cells. Biochem Biophys Res Commun 362 (2007) 44-50
    • (2007) Biochem Biophys Res Commun , vol.362 , pp. 44-50
    • Kim, J.Y.1    Kim, H.J.2    Hurt, E.M.3
  • 42
    • 47249102067 scopus 로고    scopus 로고
    • CD4+ T-regulatory cells: toward therapy for human diseases
    • Allan S.E., Broady R., Gregori S., et al. CD4+ T-regulatory cells: toward therapy for human diseases. Immunol Rev 223 (2008) 391-421
    • (2008) Immunol Rev , vol.223 , pp. 391-421
    • Allan, S.E.1    Broady, R.2    Gregori, S.3
  • 43
    • 47249124078 scopus 로고    scopus 로고
    • Human regulatory T cells: role in autoimmune disease and therapeutic opportunities
    • Brusko T.M., Putnam A.L., and Bluestone J.A. Human regulatory T cells: role in autoimmune disease and therapeutic opportunities. Immunol Rev 223 (2008) 371-390
    • (2008) Immunol Rev , vol.223 , pp. 371-390
    • Brusko, T.M.1    Putnam, A.L.2    Bluestone, J.A.3
  • 44
    • 38849108168 scopus 로고    scopus 로고
    • Ex vivo expansion of CD4+CD25+FoxP3+ T-regulatory cells based on synergy between IL-2 and 4-1BB signaling
    • Elpek K.G., Yolcu E.S., Franke D.D., et al. Ex vivo expansion of CD4+CD25+FoxP3+ T-regulatory cells based on synergy between IL-2 and 4-1BB signaling. J Immunol 179 (2007) 7295-7304
    • (2007) J Immunol , vol.179 , pp. 7295-7304
    • Elpek, K.G.1    Yolcu, E.S.2    Franke, D.D.3
  • 45
    • 53549086956 scopus 로고    scopus 로고
    • Regulatory T-cell expansion and function do not account for the impaired alloreactivity of ex vivo-expanded T cells
    • Montcuquet N., Mercier-Letondal P., Perruche S., et al. Regulatory T-cell expansion and function do not account for the impaired alloreactivity of ex vivo-expanded T cells. Immunology 125 (2008) 320-330
    • (2008) Immunology , vol.125 , pp. 320-330
    • Montcuquet, N.1    Mercier-Letondal, P.2    Perruche, S.3
  • 46
    • 34248679904 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells in transplantation: progress, challenges and prospects
    • Kang S.M., Tang Q., and Bluestone J.A. CD4+CD25+ regulatory T cells in transplantation: progress, challenges and prospects. Am J Transplant 7 (2007) 1457-1463
    • (2007) Am J Transplant , vol.7 , pp. 1457-1463
    • Kang, S.M.1    Tang, Q.2    Bluestone, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.