Regulatory T-cell expansion and function do not account for the impaired alloreactivity of ex vivo-expanded T cells

Immunology

Volumn 125, Issue 3, 2008, Pages 320-330

  Montcuquet, Nicolas ^a,b,c   Mercier Letondal, Patricia ^a,b,c   Perruche, Sylvain ^a,b,c   Duperrier, Anne ^a,b,c   Couturier, Mélanie ^a,b,c   Bouchekioua, Abdelghani ^a,b,c   Bonyhadi, Mark ^d   Ferrand, Christophe ^a,b,c   Tiberghien, Pierre ^a,b,c   Robinet, Eric ^a,b,c  

^a INSERM   (France)

^b UNIVERSITÉ DE FRANCHE COMTÉ   (France)

^c ETABLISSEMENT FRANÇAIS DU SANG   (France)

^d INVITROGEN CORPORATION   (United States)

Author keywords

Adoptive cellular immunotherapy; Alloreactivity; Cellular therapy; Cultured cells; Regulatory T cells

Indexed keywords

ALLOANTIGEN; CD28 ANTIGEN; CD3 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; INTERLEUKIN 2; TRANSCRIPTION FACTOR FOXP3;

ALLOIMMUNITY; ARTICLE; CD25+ T LYMPHOCYTE; CD4+ CD25+ T LYMPHOCYTE; CELL EXPANSION; CELL FUNCTION; CELL PROLIFERATION; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LINKED IMMUNOSPOT ASSAY; EX VIVO STUDY; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ANTIGENS, CD; CELL PROLIFERATION; CELLS, CULTURED; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; IMMUNE TOLERANCE; IMMUNOPHENOTYPING; INTERFERON-GAMMA; INTERLEUKIN-2; LYMPHOCYTE CULTURE TEST, MIXED; RECEPTORS, NERVE GROWTH FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR; T-LYMPHOCYTES, REGULATORY;

EID: 53549086956     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2008.02843.x     Document Type: Article

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