Studies toward the duocarmycin prodrugs for the antibody prodrug therapy approach

Tetrahedron Letters

Volumn 50, Issue 24, 2009, Pages 2932-2935

  Li, Lian Sheng ^a   Sinha, Subhash C ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; DOXORUBICIN; DUOCARMYCIN DERIVATIVE; DUOCARMYCIN SA; ENEDIYNE; ETOPOSIDE; FRUCTOSE BISPHOSPHATE ALDOLASE; PRO 1,2,9,9A TETRAHYDROCYCLOPROPA[C]BENZ [E]INDOLE 4 ONE TETRAMETHOXYINDOLECARBOXAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CROSS COUPLING REACTION; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; ELIMINATION REACTION; RING CLOSING METATHESIS;

EID: 65249102262     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.03.205     Document Type: Article

References (23)

1. Singh Y., Palombo M., and Sinko P.J. Curr. Med. Chem. 15 (2008) 1802
2. Rader C., Sinha S.C., Popkov M., Lerner R.A., and Barbas III C.F. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 5396
3. Wagner J., Lerner R.A., and Barbas III C.F. Science 270 (1995) 1797
4. Guo F., Das S., Mueller B.M., Barbas III C.F., Lerner R.A., and Sinha S.C. Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 11009
5. Abraham S., Guo F., Li L.-S., Rader C., Liu C., Barbas III C.F., Lerner R.A., and Sinha S.C. Proc. Natl. Acad. Sci. U.S.A. 104 (2007) 5584
6. Sinha S.C., Li L.-S., Miller G.P., Dutta S., Rader C., and Lerner R.A. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 3095
7. Shamis M., Lode H.N., and Shabat D. J. Am. Chem. Soc. 126 (2004) 1726
8. Boger D.L., and Yun W. J. Am. Chem. Soc. 116 (1994) 7996
9. MacMillan K.S., Nguyen T., Hwang I., and Boger D.L. J. Am. Chem. Soc. 131 (2009) 1187
10. Ichimura M., Ogawa T., Takahashi K., Kobayashi E., Kawamoto I., Yasuzawa T., Takahashi I., and Nakano H. J. Antibiot. 43 (1990) 1037
11. Boger D.L., and Garbaccio R.M. Acc. Chem. Res. 32 (1999) 1043
12. Atwell G.J., Wilson W.R., and Denny W.A. Bioorg. Med. Chem. Lett. 7 (1997) 1493
13. Baird R., and Winstein S. J. Am. Chem. Soc. 85 (1963) 567
14. Tietze L.F., Schuster H.J., Schmuck K., Schuberth I., and Alves F. Biorg. Med. Chem. 16 (2008) 6312
15. de Groot V.F.M.H., and Scheeren H.W. Actualite Chim. (2004) 17
16. Wojcik T., and Kiec-Kononowicz K. Curr. Med. Chem. 15 (2008) 1606
17. Shabat D., Rader C., List B., Lerner R.A., and Barbas III C.F. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 6925
18. Boger D.L., McKie J.A., and Boyce C.W. Synlett (1997) 515
19. Grubbs R.H. Tetrahedron 60 (2004) 7117
20. Gieseg M.A., Matejovic J., and Denny W.A. Anticancer Drug Des. 14 (1999) 77
21. Boger D.L., and McKie J.A. J. Org. Chem. 60 (1995) 1271
22. McKean D.R., Parrinello G., Renaldo A.F., and Stille J.K. J. Org. Chem. 52 (1987) 422
23. Fukuda Y., Itoh Y., Nakatani K., and Terashima S. Tetrahedron 50 (1994) 2793