Chemically programmed monoclonal antibodies for cancer therapy: Adaptor immunotherapy based on a covalent antibody catalyst

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 9, 2003, Pages 5396-5400

  Rader, Christoph ^a   Sinha, Subhash C ^a   Popkov, Mikhail ^a   Lerner, Richard A ^a   Barbas III, Carlos F ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIKETONE; INTEGRIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 38C2; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER; CANCER IMMUNOTHERAPY; CANCER THERAPY; CATALYST; CELL PROLIFERATION; COVALENT BOND; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; STOICHIOMETRY;

ANTIBODIES, MONOCLONAL; CATALYSIS; HUMANS; IMMUNOTHERAPY; NEOPLASMS; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0038641840     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0931308100     Document Type: Article

References (36)

1. Ehrlich, P. (1960) The Collected Papers of Paul Ehrlich, ed. Himmelweit, F. (Pergamon, London).
2. Köhler, G.& Milstein, C. (1975) Nature 256, 495-497.
3. Carter, P. (2001) Nat. Rev. Cancer 1, 118-129.
4. Reichert, J. M. (2001) Nat. Biotechnol. 19, 819-822.
5. Brekke, O. H. & Sandlie, I. (2003) Nat. Rev. Drug Discov. 2, 52-62.
6. Clynes, R. A., Towers, T. L., Presta, L. G. & Ravetch, J. V. (2000) Nat. Med. 6, 443-446.
7. van Dijk, M. A. & van de Winkel, J. G. J. (2001) Curr. Opin. Biotechnol. 5, 368-374.
8. Rehlaender, B. N. & Cho, M. J. (1998) Pharm. Res. 15, 1652-1656.
9. Shokat, K. M. & Schultz, P. G. (1991) J. Am. Chem. Soc. 113, 1861-1862.
10. Lussow, A. R., Fanget, L., Gao, L., Block, M., Buelow, R. & Pouletty, P. (1996) Transplantation 62, 1703-1708.
11. Tanaka, F., Lerner, R. A. & Barbas, C. F., III (1999) Chem. Commun. 12, 1383-1384.
12. Chmura, A. J., Orton, M. S. & Meares, C. F. (2001) Proc. Natl. Acad. Sci. USA 98, 8480-8484.
13. Lu, Y. & Low, P. S. (2002) Cancer Immunol. Immunother. 51, 153-162.
14. Tanaka, F. & Barbas, C. F., III (2002) J. Immunol. Methods 269, 67-79.
15. Wagner, J., Lerner, R. A. & Barbas, C. F., III (1995) Science 270, 1797-1800.
16. Barbas, C. F., III, Heine, A., Zhong, G., Hoffmann, T., Gramatikova, S., Bjoernstedt, R., List, B., Anderson, J., Stura, A., Wilson, I. A. & Lerner, R. A. (1997) Science 278, 2085-2092.
17. Hoffmann, T., Zhong, G., List, B., Shabat, D., Anderson, J., Gramatikova, S., Lerner, R. A. & Barbas, C. F., III (1998) J. Am. Chem. Soc. 120, 2768-2779.
18. Zhong, G., Lerner, R. A. & Barbas, C. F., III (1999) Angew. Chem. Int. Ed. Engl. 38, 3738-3741.
19. Shabat, D., Rader, C., List, B., Lerner, R. A. & Barbas, C. F., III (1999) Proc. Natl. Acad. Sci. USA 96, 6925-6930.
20. Rader, C. & List, B. (2000) Chem. Eur. J. 6, 2091-2095.
21. Shabat, D., Lode, H. N., Pertl, U. Reisfeld, R. A., Rader, C., Lerner, R. A. & Barbas, C. F., III (2001) Proc. Natl. Acad. Sci. USA 98, 7528-7533.
22. Gopin, A., Pessah, N., Shamis, M., Rader, C. & Shabat, D. (2003)Angew. Chem. Int. Ed. Engl. 42, 327-332.
23. Miller, W. H., Alberts, D. P., Bhatnagar, P. K., Bondinell, W. E., Callahan, J. F., Calvo, R. R., Cousins, R. D., Erhard, K. F., Heerding, D. A., Keenan, R. M., et al. (2000) J. Med. Chem. 43, 22-26.
24. Brooks, P. C., Clark, R. A. & Cheresh, D. A. (1994) Science 264, 569-571.
25. Miller, W. H., Keenan, R. M., Willette, R. N. & Lark, M. W. (2000) Drug Discov. Today 5, 397-408.
26. Stupack, D. G. & Cheresh, D. A. (2002) J. Cell Sci. 115, 3729-3738.
27. Engleman, V. W., Nickols, G. A., Ross, F. P., Horton, M. A., Griggs, D. W., Settle, S. L., Ruminski, P. G. & Teitelbaum, S. L. (1997) J. Clin. Invest. 99, 2284-2292.
28. Yamamoto, M., Fisher, J. E., Gentile, M., Seedor, J. G., Leu, C. T., Rodan, S. B. & Rodan, G. A. (1998) Endocrinology 139, 1411-1419.
29. Lark, M. W., Stroup, G. B., Hwang, S. M., James, I. E., Rieman, D. J., Drake, F. H., Bradbeer, J. N., Mathur, A., Erhard, K. F., Newlander, K. A., et al. (1999) J. Pharmacol. Exp. Ther. 291, 612-617.
30. Miller, W. H., Bondinell, W. E., Cousins, R. D., Erhard, K. F., Jakas, D. R., Keenan, R. M., Ku, T. W., Newlander, K. A., Ross, S. T., Haltiwanger, R. C., et al. (1999) Bioorg. Med. Chem. Lett. 9, 1807-1812.
31. Lode, H. N., Moehler, T., Xiang, R., Jonczyk, A., Gillies, S. D., Cheresh, D. A. & Reisfeld, R. A. (1999) Proc. Natl. Acad. Sci. USA 96, 1591-1596.
32. Badger, A. M., Blake, S., Kapadia, R., Sarkar, S., Levin, J., Swift, B. A., Hoffman, S. J., Stroup, G. B., Miller, W. H., Gowen, M. & Lark, M. W. (2001) Arthritis Rheum. 44, 128-137.
33. Rader, C., Popkov, M., Neves, J. A. & Barbas, C. F., III (2002) FASEB J. 16, 2000-2002.
34. Ensoli, B., Barillari, C., Salahuddin, S. Z., Gallo, R. C. & Wong-Staal, F. (1990) Nature 345, 84-86.
35. Tanaka, F., Lerner, R. A. & Barbas, C. F., III (2000) J. Am. Chem. Soc. 122, 4835-4836.
36. Cochran, A. G. (2000) Chem. Biol. 7, R85-R94.