Bioactivation of Self-Immolative Dendritic Prodrugs by Catalytic Antibody 38C2

Journal of the American Chemical Society

Volumn 126, Issue 6, 2004, Pages 1726-1731

  Shamis, Marina ^a   Lode, Holger N ^b   Shabat, Doron ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b HUMBOLDT UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; CATALYSIS; DRUG PRODUCTS; ENZYMES; SYNTHESIS (CHEMICAL); TOXICITY;

BIOACTIVATION; SELF-IMMOLATIVE DENDRIMERS;

DENDRIMERS;

38C2; CAMPTOTHECIN; CATALYTIC ANTIBODY; CATALYTIC ANTIBODY 38C2; DENDRIMER; DOXORUBICIN; PRODRUG; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; BIOASSAY; CELL GROWTH; CYTOTOXICITY; DRUG ACTIVATION; DRUG DESIGN; DRUG RELEASE; DRUG SYNTHESIS; ENZYMATIC DEGRADATION; ENZYME SUBSTRATE; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL LINE; LEUKEMIA MOLT 3 CELL; MICHAEL ADDITION;

EID: 1242336831     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja039052p     Document Type: Article

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