Multiple event activation of a generic prodrug trigger by antibody catalysis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 12, 1999, Pages 6925-6930

  Shabat, Doron ^a   Rader, Christoph ^a   List, Benjamin ^a   Lerner, Richard A ^a   Barbas III, Carlos F ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; CATALYTIC ANTIBODY; DOXORUBICIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 38C2; PRODRUG; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER CELL DESTRUCTION; CATALYSIS; CONTROLLED STUDY; DRUG ACTIVATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG TARGETING; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANIMALS; ANTIBODIES; ANTINEOPLASTIC AGENTS; CAMPTOTHECIN; DOXORUBICIN; DRUG DELIVERY SYSTEMS; DRUG DESIGN; HUMANS; MICE; PRODRUGS; TUMOR CELLS, CULTURED;

EID: 0033536048     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.12.6925     Document Type: Article

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