Intracortical perfusion of glutamate in vivo induces alterations of tau and microtubule-associated protein 2 immunoreactivity in the rat

Acta Neuropathologica

Volumn 92, Issue 2, 1996, Pages 186-196

  Irving, E A ^a   McCulloch, J ^a   Dewar, D ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Alzheimer's disease; Cytoskeleton; Glutamate; Microtubule associated protein 2; Tau

Indexed keywords

GLUTAMATE SODIUM; GLUTAMIC ACID; MICROTUBULE ASSOCIATED PROTEIN 2; TAU PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; CYTOSKELETON; IMMUNOHISTOCHEMISTRY; MALE; MICRODIALYSIS; NERVE FIBER; NEUROFIBRILLARY TANGLE; NONHUMAN; OLIGODENDROGLIA; PARIETAL LOBE; PERIKARYON; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT;

ANIMALS; CHEMOTHERAPY, CANCER, REGIONAL PERFUSION; DRUG ADMINISTRATION ROUTES; GLUTAMIC ACID; IMMUNOHISTOCHEMISTRY; INJECTIONS, SPINAL; MALE; MICROTUBULE-ASSOCIATED PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; TAU PROTEINS;

EID: 0029889986     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010050507     Document Type: Article

References (52)

1. Abe H, Yagishita S, Amano N, Iwabuchi K, Hasegawa K, Kowa K (1992) Argyrophilic glial intracytoplasmic inclusions in multiple system atrophy: immunocytochemical and ultrastructural study. Acta Neuropathol 84: 273-277
2. Biernat J, Mandelkow EM, Scroter C, LichlenbergKraag B, Steiner B, Berling B, Meyer H, Mercken M, Vandermeeren A, Goedert M, Mandelkow E (1992) The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region. EMBO J 11: 1593-1597
3. Bigot D, Hunt SP (1990) Effect of excitatory amino acids on microtubule-associated proteins in cultured cortical and spinal neurones. Neurosci Lett 111: 275-280
4. Bigot D, Matus A, Hunt SP (1991) Reorganization of the cytoskeleton in rat neurons following stimulation with excitatory amino acids in vitro. Eur J Neurosci 3: 551-558
5. Binder LI, Frankfurter A, Rebhun LI (1985) The distribution of tau in the mammalian central nervous system. J Cell Biol 101: 1371-1378
6. Bramblett GT, Goedert M, Jakes R, Merrick SE, Trojanowski JQ, Lee, VM-Y (1993) Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding. Neuron 10: 1089-1099
7. Brion J-P, Hanger DP, Bruce MT, Couck A-M, Flament-durand J, Anderton BH (1991) Tau in Alzheimer neurofibrillary tangles - N-terminal and C-terminal regions are differentially associated with paired helical filaments and the location of a putative abnormal phosphorylation site. Biochem J 273: 127-133
8. Brion J-P, Couck A-M, Robertson J, Loviny TLF, Anderton BH (1993) Neurofilament monoclonal antibodies RT97 and 8D8 recognize different modified epitopes in paired helical filament-τ in Alzheimer's disease. J Neurochem 60: 1372-1382
9. Caceres A, Binder LI, Payne MR, Bender P, Rebhun L, Steward O (1984) Differential subcellular localization of tubulin and the microtubule-associated protein MAP2 in brain tissue as revealed by immunocytochemistry with monoclonal hybridoma antibodies. J Neurosci 4: 394-410
10. Catala I, Ferrer I, Galofre E, Fabregues I (1988) Decreased numbers of dendritic spines on cortical pyramidal neurons in dementia. A quantitative Golgi study on biopsy samples. Hum Neurobiol 6: 255-259
11. Choi DW (1988) Glutamate neurotoxicity and diseases of the nervous system. Neuron 1: 623-634
12. Conner JR, Fine RE (1986) The distribution of transferrin immunoreactivity in the rat central nervous system. Brain Res 368: 319-328
13. Cotman CW, Geddes JW, Bridges RJ, Monaghan DT (1989) N-Methyl-D-aspartate receptors and Alzheimer's disease. Neurobiol Aging 10: 603-605
14. Davis DR, Brion J-P, Couck A-M, Gallo J-M, Hanger D, Ladhani K, Lewis C, Miller CJ, Rupniak T, Smith C, Anderton BH (1995) The phosphorylation state of the microtubule-associated protein tau as affected by glutamate, colchicine and β-amyloid in primary rat cortical neuronal cultures. Biochem J 309: 941-949
15. Dessi F, Charriaut-Marlangue C, Ben-Ari Y (1994) Glutamate-induced neuronal death in cerebellar culture is mediated by two distinct components: a sodium chloride component and a calcium component. Brain Res 650: 49-55
16. Dewar D, Dawson D (1995) Tau protein is altered by focal cerebral ischaemia in the rat: an immunohistochemical and immunoblotting study. Brain Res 684: 70-78
17. Dewar D, Dawson D (1995) Microtubule-associated proteins in focal cerebral ischaemia. J Neurotrauma 12: 455
18. Fujisawa H, Dawson D, Browne SE, MacKay KB, Bullock R, McCulloch J (1993) Pharmacological modification of glutamate neurotoxicity in vivo. Brain Res 629: 73-78
19. Fujisawa H, Landolt H, Macrae IM, Bullock R (1993) Glutamate neurotoxicity in vivo: the effect of ischaemia and ionic concentration in extracellular fluid. J Cereb Blood Flow Metab 13 [Suppl 1]: S784
20. Geddes JW, Schwab C, Craddock S, Wilson JL, Creed Petigrew L (1994) Alterations in τ immunostaining in the rat hippocampus following transient cerebral ischemia. J Cereb Blood Flow Metab 14: 554-564
21. Greenmyre JT, Young AB (1989) Excitatory amino acids and Alzheimer's disease. Neurobiol Aging 10: 593-602
22. Hanks SD, Flood DG (1991) Region-specific stability of dendritic extent in normal human aging and regression in Alzheimer's disease. I. CA1 of hippocampus. Brain Res 540: 63-82
23. Hatakeyama T, Matsumoto M, Brengman JK (1988) Immunohistochemical investigation of ischemic and postischemic damage after bilateral carotid artery occlusion in gerbils. Stroke 19: 1526-1534
24. Hertz L, Peng L, Westergaard N, Yudhoff M, Schousboe A (1992) Neuronal-astrocytic interactions in metabolism of transmitter amino acids of the glutamate family. In: Schousboe A, Diemer N, Kofod H (eds) Drug research related to neuroactive amino acids. Mantisgaard, Copenhagen, pp 30-50
25. Huber G, Matus A (1984) Differences in the cellular distributions of two microtubule-associated proteins, MAP1 and MAP2, in rat brain. J Neurosci 4: 151-160
26. Iwatsubo T, Hasegawa M, Ihara Y (1994) Neuronal and glial tau-positive inclusions in diverse neurologic diseases share common phosphorylation characteristics. Acta Neuropathol 88: 129-136
27. Kato S, Nakamura H, Hirano A, Ito H, Llena JF, Yen S-H (1991) Argyrophilic ubiquinated cytoplasmic inclusions of Leu-7-positive glial cells in olivopontocerebellar atrophy (multiple system atrophy). Acta Neuropathol 82: 488-493
28. Kitagawa K, Matsumoto M, Niinobe M, Mikoshiba K, Hata R, Ueda H, Handa N, Fukunaga R, Isaka Y, Kimura K, Kamada T (1989) Microtubule-associated protein 2 as a sensitive marker for cerebral ischemic damage-immunohistochemical investigation of dendritic damage. Neuroscience 31: 401-411
29. Kosik KS (1990) Tau protein in Alzheimer's disease. Curr Opin Cell Biol 2: 101-104
30. 14C glutamate autoradiography. J Cereb Blood Flow Metab 13 [Suppl 1]: S753
31. Lopresti P, Szuchet S, Papasozomenos SC, Zinkowski RP, Binder LI (1995) Functional implications for the mitrotubule-associated protein tau localization in oligodendrocytes. Proc Natl Acad Sci USA 92: 10369-10373
32. Maragos WF, Greenmyre JT, Penney JB, Young AB (1987) Glutamate dysfunction in Alzheimer's disease: a hypothesis. Trends Neurosci 10: 65-68
33. Mattson MP (1990) Antigenic changes similar to those seen in neurofibrillary tangles are elicited by glutamate and calcium influx in cultured hippocampal neurons. Neuron 4: 105-117
34. Nishimura M, Namba Y, Ikeda K, Oda M (1992) Glial fibrillary tangles with straight tubules in the brains of patients with progressive supranuclear palsy. Neurosci Lett 143: 35-38
35. Papasozomenos SC, Binder LI (1987) Phosphorylation determines two distinct species of tau in the central nervous system. Cell Motil Cytoskeleton 8: 210-226
36. Pizzi M, Valerio A, Ribola M, Spano PF, Memo M (1993) A tau antisense oligonucleotide decreases neuron sensitivity to excitotoxic injury. Neuroreport 4: 823-826
37. Pizzi M, Valerio A, Arrighi V, Belloni M, Alberici A, Spano PF, Memo M (1994) Antisense strategy unravels tau proteins as molecular risk factors for glutamate-induced neurodegeneration. Cell Mol Neurobiol 14: 569-578
38. Pizzi M, Valerio A, Arrighi V, Galli P, Belloni M, Ribola M, Alberici A, Spano PF, Memo M (1995) Inhibition of glutamate-induced neurotoxicity by a tau antisense oligonucleotide in primary culture of rat cerebellar granule cells. Eur J Neurosci 7: 1603-1613
39. Sautiere P-E, Sindou P, Couratier P, Hugon J, Wattez A, Delacourte A (1992) Tau antigenic changes induced by glutamate in rat primary culture model: a biochemical approach. Neurosci Lett 140: 206-210
40. Schousboe A, Drejer J, Hertz L (1988) Uptake and release in neurons and astrocytes in primary cultures. In: Kvamme E (ed) Glutamine and glutamate in mammals, vol 2. CRC Press, Boca Raton, pp 21-39
41. Sindou P, Couratier P, Barthe D, Hugon J (1992) A dose-dependent increase of tau immunostaining is produced by glutamate toxicity in primary neuronal cultures. Brain Res 572: 242-246
42. Sindou P, Lesort M, Couratier P, Yardin C, Esclaire F, Hugon J (1994) Glutamate increases tau phosphorylation in primary neuronal cultures from fetal rat cerebral cortex. Brain Res 646: 124-128
43. 2+ exchanger. J Neurosci 12: 430-439
44. Tomoika C, Nishoika K, Kogure K (1992) Absence of early destructive changes of cytoskeletal proteins after transient ischemia in the rat. Brain Res 586: 352-357
45. Tucker RP (1990) The roles of microtubule-associated proteins in brain morphogenesis: a review. Brain Res Rev 15: 101-120
46. Tucker RP, Binder LI, Matus AI (1988) Neuronal microtubule-associated proteins in the embryonic avian spinal cord. J Comp Neurol 271: 44-55
47. Watanabe A, Hasegawa M, Suzuki M, Takio K, Morishima-Kawashima M, Titani K, Arai T, Kosik KS, Ihara Y (1993) In vivo phosphorylation sites in fetal and adult rat tau. J Biol Chem 268: 25712-25717
48. Yamada M, Wada Y, Tsukagoshi H, Otomo E-I, Hayakawa M (1988) A quantitative Golgi study of basal dendrites of hippocampal CA1 pyramidal cells in senile dementia of Alzheimer type. J Neurol Neurosurg Psychiatry 51: 1088-1090
49. Yamada T, McGeer PL, McGeer, EG (1992) Appearance of paired nucleated, tau-positive glia in patients with progressive supranuclear palsy brain tissue. Neurosci Lett 135: 99-102
50. Yamamato K, Morimoto K, Yanagihara T (1986) Cerebral ischemia in the gerbil: transmission electron microscopic and immunoelectron microscopic investigation. Brain Res 384: 1-10
51. Yanagihara T, Brengman JM, Mushynski WE (1990) Differential vulnerability of microtubule components in cerebral ischemia. Acta Neuropathol 80: 499-505
52. Yoshida H, Ihara Y (1993) τ in paired helical filaments is functionally distinct from fetal τ: assembly incompetence of paired helical filament-τ. J Neurochem 61: 1183-1186