Synthetic approaches to the microtubule-Sabilizing sponge alkaloid ceratamine A and desbromo analogues

Journal of Organic Chemistry

Volumn 74, Issue 3, 2009, Pages 995-1006

  Nodwell, Matt ^a   Pereira, Alban ^a   Riffell, Jenna L ^a   Zimmerman, Carla ^a   Patrick, Brian O ^a   Roberge, Michel ^a   Andersen, Raymond J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDATION REACTIONS; AMIDE FUNCTIONALITIES; AMINATION REACTIONS; AMINO FUNCTIONALITIES; AROMATIC CORES; ATMOSPHERIC OXYGENS; CELL-BASED ASSAYS; DE PROTECTIONS; FUNCTIONALIZED; MICROTUBULE; MITOTIC ARRESTS; MOUSE MODELS; NATURAL PRODUCTS; OXIDATION STATE; SYNTHETIC APPROACHES; SYNTHETIC ROUTES; VINYL BROMIDES;

AMIDES; AMINATION; AMINES; AROMATIC HYDROCARBONS; BROMINE; OXYGEN;

HYDROGENATION;

4 [HYDROXY (4 METHOXYPHENYL)METHYL] 6 METHYL 2 METHYLAMINO 6H IMIDAZO[4,5 D]AZEPIN 5 ONE; ALKALOID DERIVATIVE; ANTIMITOTIC AGENT; CERATAMINE A; DESBROMOCERATAMINE A; DESMETHYLDESBROMOCERATAMINE A; UNCLASSIFIED DRUG;

AMIDATION; AMINATION; AROMATIZATION; ARTICLE; CONTROLLED STUDY; DEPROTECTION REACTION; DRUG SYNTHESIS; MICROTUBULE; MITOSIS INHIBITION; STRUCTURE ACTIVITY RELATION;

ALKALOIDS; ANIMALS; AZEPINES; BROMOBENZENES; IMIDAZOLES; PORIFERA;

EID: 64549131343     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo802322s     Document Type: Article

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