Application of a 6π-1-azatriene electrocyclization strategy to the total synthesis of the marine sponge metabolite ageladine A and biological evaluation of synthetic analogues

Journal of Organic Chemistry

Volumn 72, Issue 13, 2007, Pages 4892-4899

  Meketa, Matthew L ^a   Weinreb, Steven M ^a   Nakao, Yoichi ^b   Fusetani, Nobuhiro ^c  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b WASEDA UNIVERSITY   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; CHLOROIMIDAZOPYRIDINE; ELECTROCYCLIZATION;

BIOACTIVITY; BIOSYNTHESIS; CYCLIZATION; INORGANIC ACIDS; MARINE BIOLOGY;

METABOLITES;

2,4,5 TRIBROMOIMIDAZOLE; AGELADINE A; BORONIC ACID DERIVATIVE; CHLOROIMIDAZOPYRIDINE; GELATINASE A; N BOC PYRROLE 2 BORONIC ACID; NATURAL PRODUCT; PYRIDINE; UNCLASSIFIED DRUG; HETEROCYCLIC COMPOUND; MATRIX METALLOPROTEINASE; PYRROLE DERIVATIVE;

ARTICLE; BIOLOGICAL ACTIVITY; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; SPONGE (PORIFERA); SUZUKI REACTION; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ELECTRON; METABOLISM; SEA; SYNTHESIS;

ANIMALS; AZA COMPOUNDS; CYCLIZATION; ELECTRONS; MATRIX METALLOPROTEINASES; MOLECULAR STRUCTURE; OCEANS AND SEAS; PORIFERA; PYRROLES;

EID: 34250898546     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0707232     Document Type: Article

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