Nigricanosides A and B, antimitotic glycolipids isolated from the green alga Avrainvillea nigricans collected in Dominica

Journal of the American Chemical Society

Volumn 129, Issue 18, 2007, Pages 5822-5823

  Williams, David E ^a   Sturgeon, Christopher M ^a   Roberge, Michel ^a   Andersen, Raymond J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID ETHYL ESTER; ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; GLYCOLIPID; METHANOL; NIGRICANOSIDE A DIMETHYL ESTER; NIGRICANOSIDE B DIMETHYL ESTER; UNCLASSIFIED DRUG; WATER;

ARTICLE; BIOLOGICAL ACTIVITY; GREEN ALGA; METHYLATION; MICROTUBULE ASSEMBLY; NUCLEAR MAGNETIC RESONANCE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ALGAE, GREEN; GLYCOLIPIDS; MAGNETIC RESONANCE SPECTROSCOPY; MITOSIS;

EID: 34248529662     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0715187     Document Type: Article

References (8)

1. Anticancer Agents from Natural Products; Cragg, G. M., Kingston, D. G. I., Newman, D. J., Eds.; Taylor and Francis: New York, 2005.
2. Roberge, M.; Cinel, B.; Anderson, H. J.; Lim, L.; Jiang, X.; Xu, L.; Kelly, M. T.; Andersen, R. J. Cancer Res. 2000, 60, 5052-5058.
3. For other compounds discovered with the assay see: (a) Warabi, K.; Williams, D. E.; Patrick, B. O.; Roberge, M.; Andersen, R. J. J. Am. Chem. Soc 2007, 129, 508-509.
4. (b) Manzo, E.; van Soest, R.; Matainaho, L.; Roberge, M.; Andersen, R. J. Org. Lett. 2003, 5, 4591-4594.
5. (c) Cinel, B.; Roberge, M.; Behrisch, H.; van Ofwegen, L.; Castro, C. B.; Andersen, R. J. Org. Lett. 2000, 2, 257-260.
6. Dormann, P.; Benning, C. Trends Plant Sci. 2002, 7, 112-118.
7. For prior examples of marine algal galactolipids containing oxylipins see: (a) Jiang, Z. D.; Gerwick, W. H. Phytochem. 1990, 29, 1433-1440.
8. (b) Jiang, Z. D.; Gerwick, W. H. Lipids 1991, 26, 960-963.