Syntheses of stable-isotope labeled [M + 7] and [M + 6] 2-(methylamino)imidazole

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 45, Issue 12, 2002, Pages 1055-1064

  Zhang, Yinsheng ^a  

^a PFIZER INC   (United States)

Author keywords

2 13C,2H2 Methyl 15N amino 2 13C 1,3 15N2 imidazole; 2 2H2 methyl 15N amino 2 13C 1 15 N 3 2H imidazole

Indexed keywords

ISOTOPES; METHYLATION;

% REDUCTIONS; 2-AMINOIMIDAZOLES; 2-[13C,2H2]METHYL [15N]AMINO[2-13C-1,3-15N2] IMIDAZOLE; 2-[2H2]- METHYL[15N]AMINO[2-13C-1-15 N-3-2H]IMIDAZOLE; AMINOACETALDEHYDE; DIMETHYL ACETAL; DRUG CANDIDATES; IMIDAZOL; STABLE ISOTOPES;

ALKYLATION;

2 (METHYLAMINO)IMIDAZOLE; ACETAL DERIVATIVE; ACETALDEHYDE; CARBON; HYDROGEN; IMIDAZOLE DERIVATIVE; ISOTOPE; LITHIUM DERIVATIVE; NITROGEN 15; POTASSIUM DERIVATIVE; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; ISOTOPE LABELING; METHYLATION; REDUCTION; SYNTHESIS;

EID: 0037202345     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlcr.625     Document Type: Article

References (7)

1. Heinisch G, Reusser W. Sci Pharm 1974; 42: 19-33.
2. Briggs EM, Brown GW, Jiricny J, Meidine MF. Synthesis 1980; 295-256.
3. Calverley MJ. Synth Commun 1983; 13: 601-609.
4. Dankwardt SM, Smith DB, Porco jr JA, Nguyen CH. Synth Lett 1997; 7: 854-856.
5. Yang L, Chiu K. Tetrahedron Lett 1997; 38: 7307-7310.
6. Tanga MJ, Bupp JE. J Heterocycl Chem 1994; 31: 1641-1645.
7. Bouvier P, Mourlevat F, Pichat L, Servin A, Viel C. J Label Compd Radiopharm 1987; 24: 447-453.