Regioselective reductive cleavage of bis-benzylidene acetal: Stereoselective synthesis of anticancer agent OGT2378 and glycosidase inhibitor 1,4-dideoxy-1,4-imino-l-xylitol

Journal of Organic Chemistry

Volumn 74, Issue 7, 2009, Pages 2858-2861

  Aravind, Appu ^a   Sankar, Muthukumar Gomathi ^a   Varghese, Babu ^a   Baskaran, Sundarababu ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY MADRAS   (India)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIDEOXY 1,4 IMINO XYLITOL; 2 (HYDROXYMETHYL) 1 PENTYLPIPERIDINE 3,4,5 TRIOL; 2 (HYDROXYMETHYL) 1 TOSYLPYRROLIDINE 3,4 DIOL; 2 (TERTBUTYLDIPHENYLSILYLOXY) 1 (2,2 DIMETHYL 5 OXIRAN 2 YL) 1,3 DIOXOLAN 4 YL)ETHANOL; 4 [(TERTBUTYLDIPHENYLSILYLOXY)METHYL] 2,2 DIMETHYLHEXAHYDRO [1,3]DIOXOLO[4,5 C]PYRIDIN 7 OL; ACETAL DERIVATIVE; AMINO EPOXIDE; ANTINEOPLASTIC AGENT; AZIDO EPOSIDE; BIS BENZYLIDENE ACETAL; GLYCOSIDASE INHIBITOR; N PENTYLDEOXYIDONOJIRIMYCIN; OGT 2378; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; STEREOCHEMISTRY;

ACETALS; ANTINEOPLASTIC AGENTS; BENZYLIDENE COMPOUNDS; ENZYME INHIBITORS; GLYCOSIDE HYDROLASES; IMINO FURANOSES; IMINO SUGARS; MANNITOL; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PIPERIDINES; STEREOISOMERISM; XYLITOL;

EID: 64249155935     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo900030p     Document Type: Article

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