-
1
-
-
33644547706
-
Non-alcoholic fatty liver disease. from steatosis to cirrhosis
-
Suppl.
-
Farrell GC, Larter CZ. Non-alcoholic fatty liver disease. From steatosis to cirrhosis. Hepatology 2006 43 (Suppl. 1 S1 12.
-
(2006)
Hepatology
, vol.43
, Issue.1
-
-
Farrell, G.C.1
Larter, C.Z.2
-
2
-
-
0042165989
-
Hepatocyte apoptosis and Fas expression are prominent features of human non-alcoholic steatohepatitis
-
Feldstein AE, Canbay A, Angulo P et al. Hepatocyte apoptosis and Fas expression are prominent features of human non-alcoholic steatohepatitis. Gastroenterology 2003 125 : 437 43.
-
(2003)
Gastroenterology
, vol.125
, pp. 437-443
-
-
Feldstein, A.E.1
Canbay, A.2
Angulo, P.3
-
3
-
-
0348134733
-
Diet associated hepatic steatosis sensitizes to Fas-mediated liver injury in mice
-
Feldstein AE, Canbay A, Guicciardi ME, Higuchi H, Bronk SF, Gores GJ. Diet associated hepatic steatosis sensitizes to Fas-mediated liver injury in mice. J. Hepatol. 2003 39 : 978 83.
-
(2003)
J. Hepatol.
, vol.39
, pp. 978-983
-
-
Feldstein, A.E.1
Canbay, A.2
Guicciardi, M.E.3
Higuchi, H.4
Bronk, S.F.5
Gores, G.J.6
-
4
-
-
33747615232
-
Unfolding new mechanisms of alcoholic liver disease in the endoplasmic reticulum
-
Kaplowitz N, Ji C. Unfolding new mechanisms of alcoholic liver disease in the endoplasmic reticulum. J. Gastroenterol. Hepatol. 2006 21 : S7 9.
-
(2006)
J. Gastroenterol. Hepatol.
, vol.21
-
-
Kaplowitz, N.1
Ji, C.2
-
5
-
-
33750628734
-
Expression of p53, Bax and Bcl-2-proteins in hepatocytes in non-alcoholic fatty liver disease
-
Panasiuk A, Dzieciol J, Panasiuk B, Prokopowicz D. Expression of p53, Bax and Bcl-2-proteins in hepatocytes in non-alcoholic fatty liver disease. World J. Gastroenterol. 2006 12 : 6198 202.
-
(2006)
World J. Gastroenterol.
, vol.12
, pp. 6198-6202
-
-
Panasiuk, A.1
Dzieciol, J.2
Panasiuk, B.3
Prokopowicz, D.4
-
6
-
-
33745904468
-
In vivo assessment of liver cell apoptosis as a novel biomarker of disease severity in nonalcoholic fatty liver disease
-
Wieckowska A, Zein NN, Yerian LM, Lopez AR, McCullough AJ, Feldstein AE. In vivo assessment of liver cell apoptosis as a novel biomarker of disease severity in nonalcoholic fatty liver disease. Hepatology 2006 44 : 27 33.
-
(2006)
Hepatology
, vol.44
, pp. 27-33
-
-
Wieckowska, A.1
Zein, N.N.2
Yerian, L.M.3
Lopez, A.R.4
McCullough, A.J.5
Feldstein, A.E.6
-
7
-
-
4544335155
-
Hepatocyte apoptosis, expression of death receptors, and activation of NF-kappaB in the liver of nonalcoholic and alcoholic steatohepatitis patients
-
Ribeiro PS, Cortez-Pinto H, Sola S et al. Hepatocyte apoptosis, expression of death receptors, and activation of NF-kappaB in the liver of nonalcoholic and alcoholic steatohepatitis patients. Am. J. Gastroenterol. 2004 99 : 1708 17.
-
(2004)
Am. J. Gastroenterol.
, vol.99
, pp. 1708-1717
-
-
Ribeiro, P.S.1
Cortez-Pinto, H.2
Sola, S.3
-
8
-
-
33644813043
-
JNK1 but not JNK2 promotes the development of steatohepatitis in mice
-
Schattenberg JM, Singh R, Wang Y et al. JNK1 but not JNK2 promotes the development of steatohepatitis in mice. Hepatology 2006 43 : 163 72.
-
(2006)
Hepatology
, vol.43
, pp. 163-172
-
-
Schattenberg, J.M.1
Singh, R.2
Wang, Y.3
-
9
-
-
34948864852
-
Lack of Fas antagonism by Met in human fatty liver disease
-
Zou C, Ma J, Wang X et al. Lack of Fas antagonism by Met in human fatty liver disease. Nat. Med. 2007 13 : 1078 85.
-
(2007)
Nat. Med.
, vol.13
, pp. 1078-1085
-
-
Zou, C.1
Ma, J.2
Wang, X.3
-
10
-
-
20044374023
-
Design and validation of a histological scoring system for non-alcoholic fatty liver disease
-
Kleiner DE, Brunt EM, van Natta M et al. Design and validation of a histological scoring system for non-alcoholic fatty liver disease. Hepatology 2005 41 : 1313 21.
-
(2005)
Hepatology
, vol.41
, pp. 1313-1321
-
-
Kleiner, D.E.1
Brunt, E.M.2
Van Natta, M.3
-
11
-
-
0344010170
-
Rodent nutritional model of non-alcoholic steatohepatitis: Species, strain and sex difference studies
-
Kirsch R, Clarkson V, Shephard EG et al. Rodent nutritional model of non-alcoholic steatohepatitis: species, strain and sex difference studies. J. Gastroenterol. Hepatol. 2003 18 : 1272 82.
-
(2003)
J. Gastroenterol. Hepatol.
, vol.18
, pp. 1272-1282
-
-
Kirsch, R.1
Clarkson, V.2
Shephard, E.G.3
-
12
-
-
27744458510
-
NF-κB activation rather than TNF mediates hepatic inflammation in a murine dietary model of steatohepatitis
-
Dela Pena A, Leclercq I, Field J, George J, Jones B, Farrell G. NF-κB activation rather than TNF mediates hepatic inflammation in a murine dietary model of steatohepatitis. Gastroenterology 2005 129 : 1663 74.
-
(2005)
Gastroenterology
, vol.129
, pp. 1663-1674
-
-
Dela Pena, A.1
Leclercq, I.2
Field, J.3
George, J.4
Jones, B.5
Farrell, G.6
-
13
-
-
2342644813
-
Administration of the potent PPARalpha agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice
-
Ip E, Farrell G, Hall P, Robertson G, Leclercq I. Administration of the potent PPARalpha agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice. Hepatology 2004 39 : 1286 96.
-
(2004)
Hepatology
, vol.39
, pp. 1286-1296
-
-
Ip, E.1
Farrell, G.2
Hall, P.3
Robertson, G.4
Leclercq, I.5
-
14
-
-
0035125052
-
The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis
-
Wigg AJ, Roberts-Thomson IC, Dymock RB, McCarthy PJ, Grosse RH, Cummins AG. The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis. Gut 2001 48 : 206 11.
-
(2001)
Gut
, vol.48
, pp. 206-211
-
-
Wigg, A.J.1
Roberts-Thomson, I.C.2
Dymock, R.B.3
McCarthy, P.J.4
Grosse, R.H.5
Cummins, A.G.6
-
15
-
-
12344332455
-
Cytokines and the pathogenesis of non-alcoholic steatohepatitis
-
Diehl AM, Li ZP, Lin HZ, Yang SQ. Cytokines and the pathogenesis of non-alcoholic steatohepatitis. Gut 2005 54 : 303 6.
-
(2005)
Gut
, vol.54
, pp. 303-306
-
-
Diehl, A.M.1
Li, Z.P.2
Lin, H.Z.3
Yang, S.Q.4
-
16
-
-
30444461216
-
Insulin resistance, adiponectin, cytokines in NASH: Which is the best target to treat?
-
Larter CZ, Farrell GC. Insulin resistance, adiponectin, cytokines in NASH: which is the best target to treat? J. Hepatol. 2006 44 : 253 61.
-
(2006)
J. Hepatol.
, vol.44
, pp. 253-261
-
-
Larter, C.Z.1
Farrell, G.C.2
-
17
-
-
3042744737
-
Beyond insulin resistance in NASH: TNF-alpha or adiponectin?
-
Hui J, Hodge A, Farrell GC, Kench JG, Kriketos A, George J. Beyond insulin resistance in NASH: TNF-alpha or adiponectin? Hepatology 2004 40 : 19 22.
-
(2004)
Hepatology
, vol.40
, pp. 19-22
-
-
Hui, J.1
Hodge, A.2
Farrell, G.C.3
Kench, J.G.4
Kriketos, A.5
George, J.6
-
18
-
-
0035131872
-
TNF-alpha is not the cause of fatty liver disease in obese diabetic mice
-
Memon RA, Grunfeld C, Feingold KR. TNF-alpha is not the cause of fatty liver disease in obese diabetic mice. Nat. Med. 2001 7 : 2 3.
-
(2001)
Nat. Med.
, vol.7
, pp. 2-3
-
-
Memon, R.A.1
Grunfeld, C.2
Feingold, K.R.3
-
19
-
-
25844456719
-
Steatohepatitis induced by intragastric overfeeding in mice
-
Deng QG, She H, Cheng J et al. Steatohepatitis induced by intragastric overfeeding in mice. Hepatology 2005 42 : 905 14.
-
(2005)
Hepatology
, vol.42
, pp. 905-914
-
-
Deng, Q.G.1
She, H.2
Cheng, J.3
-
20
-
-
27444433031
-
Tumour necrosis factor related apoptosis inducing ligand (TRAIL) induces hepatic steatosis in viral hepatitis and after alcohol intake
-
Mundt B, Wirth T, Zender L et al. Tumour necrosis factor related apoptosis inducing ligand (TRAIL) induces hepatic steatosis in viral hepatitis and after alcohol intake. Gut 2005 54 : 1590 6.
-
(2005)
Gut
, vol.54
, pp. 1590-1596
-
-
Mundt, B.1
Wirth, T.2
Zender, L.3
-
21
-
-
36348941705
-
Increased hepatotoxicity of tumor necrosis factor-related apoptosis-inducing ligand in diseased human liver
-
Volkmann X, Fischer U, Bahr MJ et al. Increased hepatotoxicity of tumor necrosis factor-related apoptosis-inducing ligand in diseased human liver. Hepatology 2007 46 : 1498 508.
-
(2007)
Hepatology
, vol.46
, pp. 1498-1508
-
-
Volkmann, X.1
Fischer, U.2
Bahr, M.J.3
-
22
-
-
33644524120
-
Apoptosis and necrosis in the liver: A tale of two deaths?
-
Suppl.
-
Malhi H, Gores GJ, Lemasters JJ. Apoptosis and necrosis in the liver: a tale of two deaths? Hepatology 2006 43 (Suppl. 1 S31 44.
-
(2006)
Hepatology
, vol.43
, Issue.1
-
-
Malhi, H.1
Gores, G.J.2
Lemasters, J.J.3
-
23
-
-
1542466794
-
Critical roles of TRAIL in hepatic cell death and hepatic inflammation
-
Zheng SJ, Wang P, Tsabary G, Chen YH. Critical roles of TRAIL in hepatic cell death and hepatic inflammation. J. Clin. Invest. 2004 113 : 58 64.
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 58-64
-
-
Zheng, S.J.1
Wang, P.2
Tsabary, G.3
Chen, Y.H.4
-
24
-
-
9244237679
-
TRAIL inhibits tumor growth but is non-toxic to human hepatocytes in chimeric mice
-
Hao C, Song JH, Hsi B et al. TRAIL inhibits tumor growth but is non-toxic to human hepatocytes in chimeric mice. Cancer Res. 2004 64 : 8502 6.
-
(2004)
Cancer Res.
, vol.64
, pp. 8502-8506
-
-
Hao, C.1
Song, J.H.2
Hsi, B.3
-
25
-
-
0036687185
-
Characterization of the in vivo function of TNF-α-related apoptosis-inducing ligand, TRAIL/Apo2L, using TRAIL/Apo2L gene-deficient mice
-
Sedger LM, Glaccum MB, Schuh JCL et al. Characterization of the in vivo function of TNF-α-related apoptosis-inducing ligand, TRAIL/Apo2L, using TRAIL/Apo2L gene-deficient mice. Eur. J. Immunol. 2002 32 : 2246 54.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 2246-2254
-
-
Sedger, L.M.1
Glaccum, M.B.2
Schuh, J.C.L.3
-
26
-
-
0033565590
-
IFN-γ mediates a novel antiviral activity through dynamic modulation of TRAIL and TRAIL receptor expression
-
Sedger LM, Shows DM, Blanton RA et al. IFN-γ mediates a novel antiviral activity through dynamic modulation of TRAIL and TRAIL receptor expression. J. Immunol. 1999 163 : 920 6.
-
(1999)
J. Immunol.
, vol.163
, pp. 920-926
-
-
Sedger, L.M.1
Shows, D.M.2
Blanton, R.A.3
-
27
-
-
34547193134
-
Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity
-
Malhi H, Barreyro FJ, Isomoto H, Bronk SF, Gores GJ. Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity. Gut 2007 56 : 1124 31.
-
(2007)
Gut
, vol.56
, pp. 1124-1131
-
-
Malhi, H.1
Barreyro, F.J.2
Isomoto, H.3
Bronk, S.F.4
Gores, G.J.5
-
28
-
-
0037066427
-
The danger model: A renewed sense of self
-
Matzinger P. The danger model: a renewed sense of self. Science 2002 296 : 301 5.
-
(2002)
Science
, vol.296
, pp. 301-305
-
-
Matzinger, P.1
-
29
-
-
2442656430
-
P53 involvement in the pathogenesis of fatty liver disease
-
Yahagi N, Shimano H, Matsuzaka T et al. p53 involvement in the pathogenesis of fatty liver disease. J. Biol. Chem. 2004 279 : 20571 5.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20571-20575
-
-
Yahagi, N.1
Shimano, H.2
Matsuzaka, T.3
-
30
-
-
33847392378
-
Wild-type p53: Tumors can't stand it
-
Kasten MB. Wild-type p53: tumors can't stand it. Cell 2007 128 : 837 40.
-
(2007)
Cell
, vol.128
, pp. 837-840
-
-
Kasten, M.B.1
-
31
-
-
33845574569
-
Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1
-
Rizki G, Arnaboldi L, Gabrielli B et al. Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1. J. Lipid. Res. 2006 47 : 2280 90.
-
(2006)
J. Lipid. Res.
, vol.47
, pp. 2280-2290
-
-
Rizki, G.1
Arnaboldi, L.2
Gabrielli, B.3
-
32
-
-
39849103404
-
Adaptive mechanisms to hepatic lipid accumulation in steatohepatitis fail to prevent free fatty acid accumulation
-
Larter CZ, Yeh MM, Haigh WG et al. Adaptive mechanisms to hepatic lipid accumulation in steatohepatitis fail to prevent free fatty acid accumulation. J. Hepatol 2008 48 : 638 47.
-
(2008)
J. Hepatol
, vol.48
, pp. 638-647
-
-
Larter, C.Z.1
Yeh, M.M.2
Haigh, W.G.3
-
33
-
-
0033547306
-
Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth arrest
-
Wu GS, Burns TF, McDonald ER et al. Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth arrest. Oncogene 1999 18 : 6411 18.
-
(1999)
Oncogene
, vol.18
, pp. 6411-6418
-
-
Wu, G.S.1
Burns, T.F.2
McDonald, E.R.3
-
34
-
-
0028220041
-
Differential regulation of insulin-like growth factor i (IGF-I) and IGF binding protein-1 messenger ribonucleic acids by amino acid availability and growth hormone in rat hepatocyte primary culture
-
Thissen JP, Pucilowska JB, Underwood LE. Differential regulation of insulin-like growth factor I (IGF-I) and IGF binding protein-1 messenger ribonucleic acids by amino acid availability and growth hormone in rat hepatocyte primary culture. Endocrinology 1994 134 : 1570 6.
-
(1994)
Endocrinology
, vol.134
, pp. 1570-1576
-
-
Thissen, J.P.1
Pucilowska, J.B.2
Underwood, L.E.3
-
36
-
-
0346422479
-
Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1
-
Higuchi H, Grambihler A, Canbay A, Bronk SF, Gorest GJ. Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1. J. Biol. Chem. 2004 279 : 51 60.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 51-60
-
-
Higuchi, H.1
Grambihler, A.2
Canbay, A.3
Bronk, S.F.4
Gorest, G.J.5
-
37
-
-
33744948514
-
Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis
-
Malhi H, Bronk SF, Werneburg NW, Gores GJ. Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis. J. Biol. Chem. 2006 281 : 12093 101.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 12093-12101
-
-
Malhi, H.1
Bronk, S.F.2
Werneburg, N.W.3
Gores, G.J.4
-
38
-
-
34249824615
-
IL-6 and IGF-1 are independent prognostic factors of liver steatosis and non-alcoholic steatohepatitis in morbidly obese patients
-
Garcia-Galiano D, Sanchez-Garrido MA, Espejo I et al. IL-6 and IGF-1 are independent prognostic factors of liver steatosis and non-alcoholic steatohepatitis in morbidly obese patients. Obes. Surg. 2007 17 : 493 503.
-
(2007)
Obes. Surg.
, vol.17
, pp. 493-503
-
-
Garcia-Galiano, D.1
Sanchez-Garrido, M.A.2
Espejo, I.3
-
39
-
-
56549117448
-
Animal models of NASH: Getting both pathology and metabolic context right
-
Larter CZ, Yeh MM. Animal models of NASH: getting both pathology and metabolic context right. J. Gastroenterol. Hepatol. 2008 23 : 1635 48.
-
(2008)
J. Gastroenterol. Hepatol.
, vol.23
, pp. 1635-1648
-
-
Larter, C.Z.1
Yeh, M.M.2
|