Identification of Conserved Regulatory Elements in Mammalian Promoter Regions: A Case Study Using the PCK1 Promoter

Genomics, Proteomics and Bioinformatics

Volumn 6, Issue 3-4, 2008, Pages 129-143

  Liu, George E ^a   Weirauch, Matthew T ^b   Van Tassell, Curtis P ^a   Li, Robert W ^a   Sonstegard, Tad S ^a   Matukumalli, Lakshmi K ^a,c   Connor, Erin E ^a   Hanson, Richard W ^d   Yang, Jianqi ^d  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b University of California Santa Cruz   (United States)

^c GEORGE MASON UNIVERSITY   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

mammalian gene promoters; phosphoenolpyruvate carboxykinase; phylogenetic footprinting; transcription factor binding sites

Indexed keywords

ISOENZYME; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SP1;

ARTICLE; BINDING SITE; CYTOSOL; GEL MOBILITY SHIFT ASSAY; GENE; GENE IDENTIFICATION; GENETIC CONSERVATION; GENETIC TRANSCRIPTION; HUMAN; MAMMAL; NONHUMAN; PCK1 GENE; PHYLOGENY; PROMOTER REGION; REPORTER GENE; SENSITIVITY AND SPECIFICITY; STATISTICAL ANALYSIS; VALIDATION PROCESS;

ALGORITHMS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE, TUMOR; COMPUTATIONAL BIOLOGY; CONSERVED SEQUENCE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUCIFERASES; MICE; NORMAL DISTRIBUTION; OLIGONUCLEOTIDES; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RATS; RECOMBINANT FUSION PROTEINS; REGULATORY SEQUENCES, NUCLEIC ACID; REPRODUCIBILITY OF RESULTS; SP1 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTORS; TRANSFECTION;

MAMMALIA; RATTUS;

EID: 62949233313     PISSN: 16720229     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1672-0229(09)60001-2     Document Type: Article

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