Histopathological identification of colon cancer with microsatellite instability

American Journal of Pathology

Volumn 158, Issue 2, 2001, Pages 527-535

  Alexander, Julian ^a   Watanabe, Toshiaki ^a   Wu, Tsung Teh ^a   Rashid, Asif ^a,b   Li, Shuan ^a   Hamilton, Stanley R ^a,b,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c Eastern Cooperative Oncology Group   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; EOSIN; HEMATOXYLIN;

ARTICLE; CANCER DIAGNOSIS; COLON CANCER; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; LYMPHOCYTOSIS; MEDULLARY CARCINOMA; MICROSATELLITE INSTABILITY; MUCINOUS CARCINOMA; OBSERVER VARIATION; PRIORITY JOURNAL; SIGNET RING CARCINOMA; TUMOR DIFFERENTIATION;

EID: 0035132202     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63994-6     Document Type: Article

References (61)

1. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
2. Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences
3. Eukaryotic DNA mismatch repair
4. Clues to the pathogenesis of familial colorectal cancer
5. Genetic mapping of a locus predisposing to human colorectal cancer
6. Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome
7. Microsatellite instability in cancer of the proximal colon
8. Roles of the DNA mismatch repair genes in colorectal tumorigenesis
9. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer
10. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
11. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
12. Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients
13. Mutations of two PMS homologues in hereditary non-polyposis colorectal cancer
14. Mutation of a mutL homolog in hereditary colon cancer
15. Pathology of hereditary non-polyposis colorectal cancer
16. Hereditary nonpolyposis colorectal cancer (HNPCC): The syndrome, the genes, and historical perspectives
17. Morphology of sporadic colorectal cancer with DNA replication errors
18. Genomic instability in colorectal cancer: Relationship to clinicopathological variables and family history
19. National Cancer Institute Workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
20. Microsatellite instability is associated with the histological features of the tumor in nonfamilial colorectal cancer
21. Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability
22. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
23. Diagnostic microsatellite instability: Definition correlation with mismatch repair protein expression
24. Transforming growth factor beta type receptor gene mutations in adenomas from hereditary nonpolyposis colorectal cancer
25. Mutational inactivation of transforming growth factor β II receptor type in microsatellite stable colon cancers
26. BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines
27. A transforming growth factor beta receptor type gene mutation common in colon II gastric but rare in endometrial cancers with microsatellite instability
28. BAT-26 and BAT-40 instability in colorectal adenomas and carcinomas germline polymorphism
29. Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability
30. Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer
31. Colorectal neoplasms detected colonoscopically in at-risk members of colorectal cancer families stratified by the demonstration of DNA microsatellite instability
32. A National Cancer Institute Workshop on hereditary nonpolyposis colorectal cancer syndrome: Meeting highlights and Bethesda guidelines
33. Rectal cancer risk in hereditary nonpolyposis colorectal cancer after abdominal colectomy
34. Prognostic significance of DNA replication errors in young patients with colorectal cancer
35. Microsatellite instability in sporadic colorectal carcinoma is not an indicator of prognosis
36. Microsatellite instability: Impact on cancer progression in proximal distal colorectal cancers
37. Clinicopathologic and carcinogenetic appraisal of DNA replication error in sporadic T3NoMo stage colorectal cancer after curative resection
38. Replication error in colorectal carcinoma: Association with loss of heterozygosity at mismatch repair loci clinicopathological variables
39. Prognostic significance of microsatellite instability in sporadic mucinous colorectal cancers
40. Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers
41. Differential prognosis of replication error phenotype and loss of heterozygosity in sporadic colorectal cancer
42. p53 gene mutation, microsatellite instability and adjuvant chemotherapy: Impact on survival of 388 patients with Duke's C colon carcinoma
43. Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer
44. Microsatelite instability in sporadic mucinous rectal carcinoma: Relationship to clinicopathologic variables
45. Lymphocytic infiltration and survival in rectal cancer
46. Crohn's-like lymphoid reaction and colorectal carcinoma: A potential histologic prognosticator
47. Impact of the Crohn's-like lymphoid reaction on staging of right-sided colon cancer
48. Characterization of the inflammatory cell populations in normal colon and colonic carcinomas
49. Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair
50. Molecular predictors of survival after adjuvant chemotherapy of colon cancer
51. Characterization of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways
52. A multivariate analysis of pathologic prognostic indicators in large bowel cancer
53. Poorly differentiated colonic adenocarcinoma, medullary type. Clinical, phenotypic and molecular characteristics
54. Medullary adenocarcinoma of the colon: Clinicopathologic study of 11 cases
55. Medullary carcinoma of the breast: Interobserver variability in histopathologic diagnosis
56. Mathematical tools for demonstrating the clinical usefulness of biochemical markers
57. Towards a molecular classification of colorectal cancer
58. High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability
59. Pancreatic adenocarcinomas with DNA replication errors (RER+) are associated with wild-type K-ras and characteristic histopathology: Poor differentiation, a syncytial growth pattern, and pushing borders suggest RER+
60. Genetic, immunohistochemical, and clinical features of medullary carcinoma of the pancreas. A newly described characterized entity
61. Thymidine phosphorylase/platelet-derived endothelial cell growth factor is up-regulated in advanced solid types of gastric cancer