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Volumn 21, Issue 2, 2009, Pages 78-83

Critical role of the Polycomb and Trithorax complexes in the maintenance of CD4 T cell memory

Author keywords

Polycomb; Th memory; Transcriptional memory; Trithorax

Indexed keywords

BMI1 PROTEIN; CYTOKINE; GENE PRODUCT; MIXED LINEAGE LEUKEMIA PROTEIN; MIXED LINEAGE LEUKEMIA PROTEIN 1; NUCLEIC ACID BINDING PROTEIN; POLYCOMB GROUP PROTEIN; TRITHORAX GROUP PROTEIN; UNCLASSIFIED DRUG;

EID: 62049085937     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.smim.2009.02.001     Document Type: Review
Times cited : (39)

References (57)
  • 1
    • 2542482697 scopus 로고    scopus 로고
    • Control of T cell viability
    • Marrack P., and Kappler J. Control of T cell viability. Annu Rev Immunol 22 (2004) 765-787
    • (2004) Annu Rev Immunol , vol.22 , pp. 765-787
    • Marrack, P.1    Kappler, J.2
  • 5
    • 45449098427 scopus 로고    scopus 로고
    • Initiation and maintenance of Th2 cell identity
    • Nakayama T., and Yamashita M. Initiation and maintenance of Th2 cell identity. Curr Opin Immunol 20 (2008) 265-271
    • (2008) Curr Opin Immunol , vol.20 , pp. 265-271
    • Nakayama, T.1    Yamashita, M.2
  • 6
    • 0032862826 scopus 로고    scopus 로고
    • Polycomb group protein complexes: do different complexes regulate distinct target genes?
    • Satijn D.P., and Otte A.P. Polycomb group protein complexes: do different complexes regulate distinct target genes?. Biochim Biophys Acta 1447 (1999) 1-16
    • (1999) Biochim Biophys Acta , vol.1447 , pp. 1-16
    • Satijn, D.P.1    Otte, A.P.2
  • 7
    • 0033152770 scopus 로고    scopus 로고
    • The trithorax-group and polycomb-group chromatin modifiers: implications for disease
    • van Lohuizen M. The trithorax-group and polycomb-group chromatin modifiers: implications for disease. Curr Opin Genet Dev 9 (1999) 355-361
    • (1999) Curr Opin Genet Dev , vol.9 , pp. 355-361
    • van Lohuizen, M.1
  • 8
    • 0038349957 scopus 로고    scopus 로고
    • Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
    • Park I.K., Qian D., Kiel M., Becker M.W., Pihalja M., Weissman I.L., et al. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 423 (2003) 302-305
    • (2003) Nature , vol.423 , pp. 302-305
    • Park, I.K.1    Qian, D.2    Kiel, M.3    Becker, M.W.4    Pihalja, M.5    Weissman, I.L.6
  • 9
    • 10344258563 scopus 로고    scopus 로고
    • Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1
    • Iwama A., Oguro H., Negishi M., Kato Y., Morita Y., Tsukui H., et al. Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. Immunity 21 (2004) 843-851
    • (2004) Immunity , vol.21 , pp. 843-851
    • Iwama, A.1    Oguro, H.2    Negishi, M.3    Kato, Y.4    Morita, Y.5    Tsukui, H.6
  • 10
    • 0242667922 scopus 로고    scopus 로고
    • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    • Molofsky A.V., Pardal R., Iwashita T., Park I.K., Clarke M.F., and Morrison S.J. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425 (2003) 962-967
    • (2003) Nature , vol.425 , pp. 962-967
    • Molofsky, A.V.1    Pardal, R.2    Iwashita, T.3    Park, I.K.4    Clarke, M.F.5    Morrison, S.J.6
  • 11
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • Lessard J., and Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 423 (2003) 255-260
    • (2003) Nature , vol.423 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 13
    • 4544275712 scopus 로고    scopus 로고
    • Interleukin (IL)-4-independent maintenance of histone modification of the IL-4 gene loci in memory Th2 cells
    • Yamashita M., Shinnakasu R., Nigo Y., Kimura M., Hasegawa A., Taniguchi M., et al. Interleukin (IL)-4-independent maintenance of histone modification of the IL-4 gene loci in memory Th2 cells. J Biol Chem 279 (2004) 39454-39464
    • (2004) J Biol Chem , vol.279 , pp. 39454-39464
    • Yamashita, M.1    Shinnakasu, R.2    Nigo, Y.3    Kimura, M.4    Hasegawa, A.5    Taniguchi, M.6
  • 14
    • 0034162511 scopus 로고    scopus 로고
    • Qualitative changes accompany memory T cell generation: faster, more effective responses at lower doses of antigen
    • Rogers P.R., Dubey C., and Swain S.L. Qualitative changes accompany memory T cell generation: faster, more effective responses at lower doses of antigen. J Immunol 164 (2000) 2338-2346
    • (2000) J Immunol , vol.164 , pp. 2338-2346
    • Rogers, P.R.1    Dubey, C.2    Swain, S.L.3
  • 15
    • 0036672918 scopus 로고    scopus 로고
    • Maintaining the norm: T-cell homeostasis
    • Jameson S.C. Maintaining the norm: T-cell homeostasis. Nat Rev Immunol 2 (2002) 547-556
    • (2002) Nat Rev Immunol , vol.2 , pp. 547-556
    • Jameson, S.C.1
  • 16
    • 0038655228 scopus 로고    scopus 로고
    • Cytokine control of memory T-cell development and survival
    • Schluns K.S., and Lefrancois L. Cytokine control of memory T-cell development and survival. Nat Rev Immunol 3 (2003) 269-279
    • (2003) Nat Rev Immunol , vol.3 , pp. 269-279
    • Schluns, K.S.1    Lefrancois, L.2
  • 18
    • 0038487052 scopus 로고    scopus 로고
    • Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells
    • Seddon B., Tomlinson P., and Zamoyska R. Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells. Nat Immunol 4 (2003) 680-686
    • (2003) Nat Immunol , vol.4 , pp. 680-686
    • Seddon, B.1    Tomlinson, P.2    Zamoyska, R.3
  • 20
    • 0347594000 scopus 로고    scopus 로고
    • IL-7 promotes the transition of CD4 effectors to persistent memory cells
    • Li J., Huston G., and Swain S.L. IL-7 promotes the transition of CD4 effectors to persistent memory cells. J Exp Med 198 (2003) 1807-1815
    • (2003) J Exp Med , vol.198 , pp. 1807-1815
    • Li, J.1    Huston, G.2    Swain, S.L.3
  • 21
    • 9244243110 scopus 로고    scopus 로고
    • STATs as critical mediators of signal transduction and transcription: lessons learned from STAT5
    • Paukku K., and Silvennoinen O. STATs as critical mediators of signal transduction and transcription: lessons learned from STAT5. Cytokine Growth Factor Rev 15 (2004) 435-455
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 435-455
    • Paukku, K.1    Silvennoinen, O.2
  • 22
    • 0043127142 scopus 로고    scopus 로고
    • The pims and outs of survival signaling: role for the Pim-2 protein kinase in the suppression of apoptosis by cytokines
    • White E. The pims and outs of survival signaling: role for the Pim-2 protein kinase in the suppression of apoptosis by cytokines. Genes Dev 17 (2003) 1813-1816
    • (2003) Genes Dev , vol.17 , pp. 1813-1816
    • White, E.1
  • 23
    • 33846410668 scopus 로고    scopus 로고
    • Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells
    • Riou C., Yassine-Diab B., Van grevenynghe J., Somogyi R., Greller L.D., Gagnon D., et al. Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells. J Exp Med 204 (2007) 79-91
    • (2007) J Exp Med , vol.204 , pp. 79-91
    • Riou, C.1    Yassine-Diab, B.2    Van grevenynghe, J.3    Somogyi, R.4    Greller, L.D.5    Gagnon, D.6
  • 24
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: a play in three Akts
    • Datta S.R., Brunet A., and Greenberg M.E. Cellular survival: a play in three Akts. Genes Dev 13 (1999) 2905-2927
    • (1999) Genes Dev , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 25
    • 11144357466 scopus 로고    scopus 로고
    • IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
    • Hu M.C., Lee D.F., Xia W., Golfman L.S., Ou-Yang F., Yang J.Y., et al. IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a. Cell 117 (2004) 225-237
    • (2004) Cell , vol.117 , pp. 225-237
    • Hu, M.C.1    Lee, D.F.2    Xia, W.3    Golfman, L.S.4    Ou-Yang, F.5    Yang, J.Y.6
  • 26
    • 33646474850 scopus 로고    scopus 로고
    • OX40-OX40 ligand interaction through T cell-T cell contact contributes to CD4 T cell longevity
    • Soroosh P., Ine S., Sugamura K., and Ishii N. OX40-OX40 ligand interaction through T cell-T cell contact contributes to CD4 T cell longevity. J Immunol 176 (2006) 5975-5987
    • (2006) J Immunol , vol.176 , pp. 5975-5987
    • Soroosh, P.1    Ine, S.2    Sugamura, K.3    Ishii, N.4
  • 27
    • 2642548330 scopus 로고    scopus 로고
    • The generation of T cell memory: a review describing the molecular and cellular events following OX40 (CD134) engagement
    • Weinberg A.D., Evans D.E., Thalhofer C., Shi T., and Prell R.A. The generation of T cell memory: a review describing the molecular and cellular events following OX40 (CD134) engagement. J Leukoc Biol 75 (2004) 962-972
    • (2004) J Leukoc Biol , vol.75 , pp. 962-972
    • Weinberg, A.D.1    Evans, D.E.2    Thalhofer, C.3    Shi, T.4    Prell, R.A.5
  • 28
    • 3042598052 scopus 로고    scopus 로고
    • Essential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene loci
    • Yamashita M., Ukai-Tadenuma M., Miyamoto T., Sugaya K., Hosokawa H., Hasegawa A., et al. Essential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene loci. J Biol Chem 279 (2004) 26983-26990
    • (2004) J Biol Chem , vol.279 , pp. 26983-26990
    • Yamashita, M.1    Ukai-Tadenuma, M.2    Miyamoto, T.3    Sugaya, K.4    Hosokawa, H.5    Hasegawa, A.6
  • 29
    • 1242274405 scopus 로고    scopus 로고
    • GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells
    • Pai S.Y., Truitt M.L., and Ho I.C. GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells. Proc Natl Acad Sci USA 101 (2004) 1993-1998
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1993-1998
    • Pai, S.Y.1    Truitt, M.L.2    Ho, I.C.3
  • 31
    • 0037072601 scopus 로고    scopus 로고
    • Molecular biology. Chromatin higher order folding-wrapping up transcription
    • Horn P.J., and Peterson C.L. Molecular biology. Chromatin higher order folding-wrapping up transcription. Science 297 (2002) 1824-1827
    • (2002) Science , vol.297 , pp. 1824-1827
    • Horn, P.J.1    Peterson, C.L.2
  • 32
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T., and Allis C.D. Translating the histone code. Science 293 (2001) 1074-1080
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 33
    • 33845799903 scopus 로고    scopus 로고
    • Polycomb silencing mechanisms and the management of genomic programmes
    • Schwartz Y.B., and Pirrotta V. Polycomb silencing mechanisms and the management of genomic programmes. Nat Rev Genet 8 (2007) 9-22
    • (2007) Nat Rev Genet , vol.8 , pp. 9-22
    • Schwartz, Y.B.1    Pirrotta, V.2
  • 34
    • 0018240421 scopus 로고
    • A gene complex controlling segmentation in Drosophila
    • Lewis E.B. A gene complex controlling segmentation in Drosophila. Nature 276 (1978) 565-570
    • (1978) Nature , vol.276 , pp. 565-570
    • Lewis, E.B.1
  • 35
    • 0036340237 scopus 로고    scopus 로고
    • The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans
    • Levine S.S., Weiss A., Erdjument-Bromage H., Shao Z., Tempst P., and Kingston R.E. The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans. Mol Cell Biol 22 (2002) 6070-6078
    • (2002) Mol Cell Biol , vol.22 , pp. 6070-6078
    • Levine, S.S.1    Weiss, A.2    Erdjument-Bromage, H.3    Shao, Z.4    Tempst, P.5    Kingston, R.E.6
  • 36
    • 0043127085 scopus 로고    scopus 로고
    • Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains
    • Fischle W., Wang Y., Jacobs S.A., Kim Y., Allis C.D., and Khorasanizadeh S. Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains. Genes Dev 17 (2003) 1870-1881
    • (2003) Genes Dev , vol.17 , pp. 1870-1881
    • Fischle, W.1    Wang, Y.2    Jacobs, S.A.3    Kim, Y.4    Allis, C.D.5    Khorasanizadeh, S.6
  • 37
    • 0036337565 scopus 로고    scopus 로고
    • The Drosophila trithorax protein is a coactivator required to prevent re-establishment of polycomb silencing
    • Poux S., Horard B., Sigrist C.J., and Pirrotta V. The Drosophila trithorax protein is a coactivator required to prevent re-establishment of polycomb silencing. Development 129 (2002) 2483-2493
    • (2002) Development , vol.129 , pp. 2483-2493
    • Poux, S.1    Horard, B.2    Sigrist, C.J.3    Pirrotta, V.4
  • 38
    • 2442594080 scopus 로고    scopus 로고
    • The histone methyltransferases Trithorax and Ash1 prevent transcriptional silencing by Polycomb group proteins
    • Klymenko T., and Muller J. The histone methyltransferases Trithorax and Ash1 prevent transcriptional silencing by Polycomb group proteins. EMBO Rep 5 (2004) 373-377
    • (2004) EMBO Rep , vol.5 , pp. 373-377
    • Klymenko, T.1    Muller, J.2
  • 39
    • 0025833975 scopus 로고
    • Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias
    • Ziemin-van der Poel S., McCabe N.R., Gill H.J., Espinosa III R., Patel Y., Harden A., et al. Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias. Proc Natl Acad Sci USA 88 (1991) 10735-10739
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 10735-10739
    • Ziemin-van der Poel, S.1    McCabe, N.R.2    Gill, H.J.3    Espinosa III, R.4    Patel, Y.5    Harden, A.6
  • 40
    • 0026496887 scopus 로고
    • The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene
    • Gu Y., Nakamura T., Alder H., Prasad R., Canaani O., Cimino G., et al. The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene. Cell 71 (1992) 701-708
    • (1992) Cell , vol.71 , pp. 701-708
    • Gu, Y.1    Nakamura, T.2    Alder, H.3    Prasad, R.4    Canaani, O.5    Cimino, G.6
  • 41
    • 0026454451 scopus 로고
    • Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias
    • Tkachuk D.C., Kohler S., and Cleary M.L. Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias. Cell 71 (1992) 691-700
    • (1992) Cell , vol.71 , pp. 691-700
    • Tkachuk, D.C.1    Kohler, S.2    Cleary, M.L.3
  • 42
    • 0027279628 scopus 로고
    • Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations
    • Thirman M.J., Gill H.J., Burnett R.C., Mbangkollo D., McCabe N.R., Kobayashi H., et al. Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations. N Engl J Med 329 (1993) 909-914
    • (1993) N Engl J Med , vol.329 , pp. 909-914
    • Thirman, M.J.1    Gill, H.J.2    Burnett, R.C.3    Mbangkollo, D.4    McCabe, N.R.5    Kobayashi, H.6
  • 43
  • 44
    • 18744373853 scopus 로고    scopus 로고
    • MLL targets SET domain methyltransferase activity to Hox gene promoters
    • Milne T.A., Briggs S.D., Brock H.W., Martin M.E., Gibbs D., Allis C.D., et al. MLL targets SET domain methyltransferase activity to Hox gene promoters. Mol Cell 10 (2002) 1107-1117
    • (2002) Mol Cell , vol.10 , pp. 1107-1117
    • Milne, T.A.1    Briggs, S.D.2    Brock, H.W.3    Martin, M.E.4    Gibbs, D.5    Allis, C.D.6
  • 45
    • 18744410349 scopus 로고    scopus 로고
    • ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation
    • Nakamura T., Mori T., Tada S., Krajewski W., Rozovskaia T., Wassell R., et al. ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation. Mol Cell 10 (2002) 1119-1128
    • (2002) Mol Cell , vol.10 , pp. 1119-1128
    • Nakamura, T.1    Mori, T.2    Tada, S.3    Krajewski, W.4    Rozovskaia, T.5    Wassell, R.6
  • 46
    • 33644746220 scopus 로고    scopus 로고
    • Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells
    • Luckey C.J., Bhattacharya D., Goldrath A.W., Weissman I.L., Benoist C., and Mathis D. Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells. Proc Natl Acad Sci USA 103 (2006) 3304-3309
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 3304-3309
    • Luckey, C.J.1    Bhattacharya, D.2    Goldrath, A.W.3    Weissman, I.L.4    Benoist, C.5    Mathis, D.6
  • 48
    • 0033552813 scopus 로고    scopus 로고
    • The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
    • Jacobs J.J., Kieboom K., Marino S., DePinho R.A., and van Lohuizen M. The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 397 (1999) 164-168
    • (1999) Nature , vol.397 , pp. 164-168
    • Jacobs, J.J.1    Kieboom, K.2    Marino, S.3    DePinho, R.A.4    van Lohuizen, M.5
  • 49
    • 0037309326 scopus 로고    scopus 로고
    • Tumor suppression by Ink4a-Arf: progress and puzzles
    • Lowe S.W., and Sherr C.J. Tumor suppression by Ink4a-Arf: progress and puzzles. Curr Opin Genet Dev 13 (2003) 77-83
    • (2003) Curr Opin Genet Dev , vol.13 , pp. 77-83
    • Lowe, S.W.1    Sherr, C.J.2
  • 51
    • 0037131523 scopus 로고    scopus 로고
    • Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites
    • Czermin B., Melfi R., McCabe D., Seitz V., Imhof A., and Pirrotta V. Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell 111 (2002) 185-196
    • (2002) Cell , vol.111 , pp. 185-196
    • Czermin, B.1    Melfi, R.2    McCabe, D.3    Seitz, V.4    Imhof, A.5    Pirrotta, V.6
  • 52
    • 18644383738 scopus 로고    scopus 로고
    • Histone methyltransferase activity of a Drosophila Polycomb group repressor complex
    • Muller J., Hart C.M., Francis N.J., Vargas M.L., Sengupta A., Wild B., et al. Histone methyltransferase activity of a Drosophila Polycomb group repressor complex. Cell 111 (2002) 197-208
    • (2002) Cell , vol.111 , pp. 197-208
    • Muller, J.1    Hart, C.M.2    Francis, N.J.3    Vargas, M.L.4    Sengupta, A.5    Wild, B.6
  • 53
    • 0036830642 scopus 로고    scopus 로고
    • Role of histone H3 lysine 27 methylation in Polycomb-group silencing
    • Cao R., Wang L., Wang H., Xia L., Erdjument-Bromage H., Tempst P., et al. Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 298 (2002) 1039-1043
    • (2002) Science , vol.298 , pp. 1039-1043
    • Cao, R.1    Wang, L.2    Wang, H.3    Xia, L.4    Erdjument-Bromage, H.5    Tempst, P.6
  • 54
    • 0037111831 scopus 로고    scopus 로고
    • Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein
    • Kuzmichev A., Nishioka K., Erdjument-Bromage H., Tempst P., and Reinberg D. Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. Genes Dev 16 (2002) 2893-2905
    • (2002) Genes Dev , vol.16 , pp. 2893-2905
    • Kuzmichev, A.1    Nishioka, K.2    Erdjument-Bromage, H.3    Tempst, P.4    Reinberg, D.5
  • 56
    • 7744228427 scopus 로고    scopus 로고
    • Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation
    • de Napoles M., Mermoud J.E., Wakao R., Tang Y.A., Endoh M., Appanah R., et al. Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. Dev Cell 7 (2004) 663-676
    • (2004) Dev Cell , vol.7 , pp. 663-676
    • de Napoles, M.1    Mermoud, J.E.2    Wakao, R.3    Tang, Y.A.4    Endoh, M.5    Appanah, R.6
  • 57
    • 2942715029 scopus 로고    scopus 로고
    • Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression
    • Yokoyama A., Wang Z., Wysocka J., Sanyal M., Aufiero D.J., Kitabayashi I., et al. Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression. Mol Cell Biol 24 (2004) 5639-5649
    • (2004) Mol Cell Biol , vol.24 , pp. 5639-5649
    • Yokoyama, A.1    Wang, Z.2    Wysocka, J.3    Sanyal, M.4    Aufiero, D.J.5    Kitabayashi, I.6


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