The Drosophila Trithorax protein is a coactivator required to prevent re-establishment of polycomb silencing

Development

Volumn 129, Issue 10, 2002, Pages 2483-2493

  Poux, Sylvain ^a   Horard, Béatrice ^a   Sigrist, Christian J A ^a   Pirrotta, Vincenzo ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Chromatin silencing; Coactivator; Drosophila melanogaster; Epigenetic memory; Homeotic genes; Polycomb

Indexed keywords

HISTONE ACETYLTRANSFERASE; HYBRID PROTEIN; INSECT PROTEIN; PROTEIN POLYCOMB; PROTEIN TRITHORAX; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEACETYLATION; DNA RESPONSIVE ELEMENT; DROSOPHILA; EMBRYO; GENE ACTIVATION; GENE EXPRESSION; GENE REPRESSION; GENE SILENCING; HOMEOBOX; IMAGINAL DISC; IMMUNOPRECIPITATION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN TARGETING;

ACETYLATION; ANIMALS; BINDING SITES; CELL CYCLE PROTEINS; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE SILENCING; HISTONE ACETYLTRANSFERASES; HISTONES; HOMEODOMAIN PROTEINS; INSECT PROTEINS; RECOMBINANT PROTEINS; RESPONSE ELEMENTS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

ANIMALIA; DROSOPHILA MELANOGASTER; HEXAPODA; INSECTA; MELANOGASTER;

EID: 0036337565     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Functional interaction between the coactivator Drosophila CREB-binding protein and ASH1, a member of the trithorax group of chromatin modifiers
2. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
3. The MCP silencer of the Drosophila Abd-B gene requires both Pleiohomeotic and GAGA factor for the maintenance of repression
4. Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo
5. Genetic interactions between the Polycomb locus and the Antennapedia and bithorax complexes of Drosophila
6. The Drosophila Fab-7 chromosomal element conveys epigenetic inheritance during mitosis and meiosis
7. Epigenetic inheritance of active chromatin after removal of the main transactivator
8. A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression
9. The Drosophila trithorax protein binds to specific chromosomal sites and is co-localized with Polycomb at many sites
10. The GAGA factor of Drosophila interacts with SAP18, a Sin3-associated polypeptide
11. The Trithorax-like gene encodes the Drosophila GAGA factor
12. A novel genetic system to detect protein-protein interactions
13. A Polycomb and GAGA dependent silencer adjoins the Fab-7 boundary in the Drosophila bithorax complex
14. Site-Specific recognition of a 70-base-pair element containing d(GA)(n) repeats mediates bithoraxoid Polycomb group response element-dependent silencing
15. Structure of a Polycomb response element and in vitro binding of Polycomb group complexes containing GAGA factor
16. Abdominal gene organization
17. The Drosophila Brahma complex is an essential coactivator for the trithorax group protein Zeste
18. Repression and activation by multiprotein complexes that alter chromatin structure
19. Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo
20. Binding of Trithorax and Polycomb proteins to the bithorax complex: Dynamic changes during early Drosophila embryogenesis
21. The Drosophila trithorax group proteins BRM, ASH1 and ASH2 are subunits of distinct protein complexes
22. The role of Polycomb group and trithorax group chromatin complexes in the maintenance of determined cell states
23. PcG complexes and chromatin silencing
24. Distinct parasegmental and imaginal enhancers and the establishment of the expression pattern of the Ubx gene
25. Recruitment of components of Polycomb Group chromatin complexes in Drosophila
26. Establishment of Polycomb silencing requires a transient interaction between PC and ESC
27. Regulation of chromatin structure by site-specific histone H3 methyltransferases
28. The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex
29. Trithorax and ASH1 interact directly and associate with the trithorax group-responsive bxd region of the Ultrabithorax promoter
30. Homoeosis in Drosophila: Anterior and posterior transformations of Polycomb lethal embryos
31. A Drosophila Polycomb group complex includes Zeste and dTAFII proteins
32. Stabilization of chromatin structure by PRC1, a Polycomb complex
33. Chromatin insulator elements block the silencing of a target gene by the Drosophila Polycomb response element (PRE) but allow trans interactions between PREs on different chromosomes
34. The polycomb group protein complex of Drosophila melanogaster has different compositions at different target genes
35. Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin
36. Trithorax-and Polycomb-group response elements within an Ultrabithorax transcription maintenance unit consist of closely situated but separable sequences
37. Methylation of Histone H4 at Arginine 3 Facilitates Transcriptional Activation by Nuclear Hormone Receptor