Helenanolide-type sesquiterpene lactones - III. Rates and stereochemistry in the reaction of helenalin and related helenanolides with sulfhydryl containing biomolecules

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 4, 1997, Pages 645-653

  Schmidt, Thomas J ^a,b  

^a Inst Pharmazeut Biol Heinrich H   (Germany)

^b LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; GLUTATHIONE; HELENALIN; SESQUITERPENE LACTONE; THIOL DERIVATIVE;

ARTICLE; DRUG ACTIVITY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOCHEMISTRY; STEREOSPECIFICITY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BINDING, COMPETITIVE; CYSTEINE; GLUTATHIONE; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; SESQUITERPENES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TOXINS, BIOLOGICAL;

EID: 0030904120     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(97)00003-5     Document Type: Article

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