15-Deoxy-Δ12,14-prostaglandin J2 inhibits fibrogenic response in human hepatoma cells

Toxicology Letters

Volumn 187, Issue 1, 2009, Pages 22-27

  Suk, Fat Moon ^a   Chen, Chien Ho ^b   Lin, Shyr Yi ^a   Cheng, Ching Ju ^b   Yen, Shish Jung ^c   Hung, Ling Fang ^b   Liu, Der Zen ^a,d   Liang, Yu Chih ^a,b  

^a TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI CITY HOSPITAL   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

15 Deoxy 12,14 prostaglandin J2; CTGF; Fibrosis; Hepatoma; TGF

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; BEZAFIBRATE; CONNECTIVE TISSUE GROWTH FACTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIRINIXIC ACID; SMAD2 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR ALPHA; TROGLITAZONE;

ARTICLE; CANCER CELL CULTURE; CELL STRAIN HEPG2; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FIBROGENESIS; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER FIBROSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL SURVIVAL; CONNECTIVE TISSUE GROWTH FACTOR; FIBROSIS; GENE EXPRESSION; HEPATIC STELLATE CELLS; HEPATOCYTES; HUMANS; IMMUNOLOGIC FACTORS; LIVER CIRRHOSIS; PHOSPHORYLATION; PROSTAGLANDIN D2; RNA, MESSENGER; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 61849184930     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.01.019     Document Type: Article

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