메뉴 건너뛰기




Volumn 37, Issue 2, 2005, Pages 138-145

HCV core protein promotes liver fibrogenesis via up-regulation of CTGF with TGF-β1

Author keywords

Connective tissue growth factor; Fibrogenesis; Hepatitis C virus; Liver cirrhosis; Stellate cell

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; CORE PROTEIN; GELATINASE A; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1;

EID: 21044433414     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2005.19     Document Type: Article
Times cited : (88)

References (41)
  • 1
    • 0032077407 scopus 로고    scopus 로고
    • Microfabrication of hepatocyte/fibroblast co-cultures: Role of homotypic cell interactions
    • Bhatia SN, Balls UJ, Yarmush ML, Toner M. Microfabrication of hepatocyte/fibroblast co-cultures: role of homotypic cell interactions. Biotechnol Prog 1998;14:378-87
    • (1998) Biotechnol Prog , vol.14 , pp. 378-387
    • Bhatia, S.N.1    Balls, U.J.2    Yarmush, M.L.3    Toner, M.4
  • 2
    • 0035980914 scopus 로고    scopus 로고
    • Chronic liver injury, TGF-beta, and cancer
    • Bissell DM. Chronic liver injury, TGF-beta, and cancer. Exp Mol Med 2001;33:179-190
    • (2001) Exp Mol Med , vol.33 , pp. 179-190
    • Bissell, D.M.1
  • 3
    • 18244365110 scopus 로고    scopus 로고
    • Of Mice and men: A small animal model of hepatitis C virus replication
    • Brass V, Blum HE, Moradpour D, Of Mice and men: a small animal model of hepatitis C virus replication. Hepatology 2002;35:722-4
    • (2002) Hepatology , vol.35 , pp. 722-724
    • Brass, V.1    Blum, H.E.2    Moradpour, D.3
  • 5
    • 0035971161 scopus 로고    scopus 로고
    • The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts
    • Chen CC, Chen N, Lau LF. The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts. J Biol Chem 2001;276:10443-52
    • (2001) J Biol Chem , vol.276 , pp. 10443-10452
    • Chen, C.C.1    Chen, N.2    Lau, L.F.3
  • 8
    • 0000429470 scopus 로고
    • Isolation and culture of hepatic nonparenchymal cells
    • Tyson C, Frazier J, editors. Academic Press California: San Diego
    • Friedman S. Isolation and culture of hepatic nonparenchymal cells. In: in vitro biological systems. Volume 1. Tyson C, Frazier J, editors. Academic Press California: San Diego, 1993:292310
    • (1993) In Vitro Biological Systems , vol.1 , pp. 292310
    • Friedman, S.1
  • 9
    • 0034723290 scopus 로고    scopus 로고
    • Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
    • Friedman SL. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem 2000;275:2247-50
    • (2000) J Biol Chem , vol.275 , pp. 2247-2250
    • Friedman, S.L.1
  • 11
    • 17344381535 scopus 로고    scopus 로고
    • Hepatitis C virus biology
    • Giannini C, Brechot C. Hepatitis C virus biology. Cell Death Differ 2003;10 Suppl 1:527-38
    • (2003) Cell Death Differ , vol.10 , Issue.SUPPL. 1 , pp. 527-538
    • Giannini, C.1    Brechot, C.2
  • 12
    • 0037114401 scopus 로고    scopus 로고
    • Novel approach for achieving double-layered cell sheets co-culture: Overlaying endothelial cell sheets onto monolayer hepatocytes utilizing temperature-responsive culture dishes
    • Harimoto M, Yamato M, Hirose M, Takahashi C, Isoi Y, Kikuchi A, Okano T. Novel approach for achieving double-layered cell sheets co-culture: overlaying endothelial cell sheets onto monolayer hepatocytes utilizing temperature-responsive culture dishes. J Biomed Mater Res 2002;62:464-70
    • (2002) J Biomed Mater Res , vol.62 , pp. 464-470
    • Harimoto, M.1    Yamato, M.2    Hirose, M.3    Takahashi, C.4    Isoi, Y.5    Kikuchi, A.6    Okano, T.7
  • 13
    • 0018854046 scopus 로고
    • Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates
    • Heussen C, Dowdle EB. Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates. Anal Biochem 1980;102:196-202
    • (1980) Anal Biochem , vol.102 , pp. 196-202
    • Heussen, C.1    Dowdle, E.B.2
  • 15
    • 0027229995 scopus 로고
    • Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair
    • Igarashi A, Okochi H, Bradham DM, Grotendorst GR. Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair. Mol Biol Cell 1993;4:637-45
    • (1993) Mol Biol Cell , vol.4 , pp. 637-645
    • Igarashi, A.1    Okochi, H.2    Bradham, D.M.3    Grotendorst, G.R.4
  • 16
    • 0029996247 scopus 로고    scopus 로고
    • Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders
    • Igarashi A, Nashiro K, Kikuchi K, Sato S, Ihn H, Fujimoto M, Grotendorst GR, Takehara K. Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders. J Invest Dermatol 1996;106:729-33
    • (1996) J Invest Dermatol , vol.106 , pp. 729-733
    • Igarashi, A.1    Nashiro, K.2    Kikuchi, K.3    Sato, S.4    Ihn, H.5    Fujimoto, M.6    Grotendorst, G.R.7    Takehara, K.8
  • 18
    • 0034048521 scopus 로고    scopus 로고
    • Basement membrane zone remodeling during appendageal development in human fetal skin. The absence of type VII collagen is associated with gelatinase-A (MMP2) activity
    • Karelina W, Bannikov GA, Eisen AZ. Basement membrane zone remodeling during appendageal development in human fetal skin. The absence of type VII collagen is associated with gelatinase-A (MMP2) activity. J Invest Dermatol 2000;114:371-5
    • (2000) J Invest Dermatol , vol.114 , pp. 371-375
    • Karelina, W.1    Bannikov, G.A.2    Eisen, A.Z.3
  • 19
    • 0032742051 scopus 로고    scopus 로고
    • Rat liver myofibroblasts and hepatic stellate cells: Different cell populations of the fibroblast lineage with fibrogenic potential
    • Knittel T, Kobold D, Saile B, Grundmann A, Neubauer K, Piscaglia F, Ramadori G. Rat liver myofibroblasts and hepatic stellate cells: different cell populations of the fibroblast lineage with fibrogenic potential. Gastroenterology 1999;117:1205-21
    • (1999) Gastroenterology , vol.117 , pp. 1205-1221
    • Knittel, T.1    Kobold, D.2    Saile, B.3    Grundmann, A.4    Neubauer, K.5    Piscaglia, F.6    Ramadori, G.7
  • 21
    • 0036545885 scopus 로고    scopus 로고
    • Connective tissue growth factor: A new and important player in the pathogenesis of fibrosis
    • Leask A, Holmes A, Abraham DJ. Connective tissue growth factor: a new and important player in the pathogenesis of fibrosis. Curr Rheumatol Rep 2002;4:136-42
    • (2002) Curr Rheumatol Rep , vol.4 , pp. 136-142
    • Leask, A.1    Holmes, A.2    Abraham, D.J.3
  • 26
    • 0026334457 scopus 로고
    • Nucleotide sequence and mutation rate of the H strain of hepatitis C virus
    • Ogata N, Alter HJ, Miller RH, Purcell RH, Nucleotide sequence and mutation rate of the H strain of hepatitis C virus. Proc Natl Acad Sci USA 1991;88:3392-6
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3392-3396
    • Ogata, N.1    Alter, H.J.2    Miller, R.H.3    Purcell, R.H.4
  • 27
    • 0036165333 scopus 로고    scopus 로고
    • Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein
    • Okuda M, Li K, Beard MR, Showalter LA, Scholle F, Lemon SM, Weinman SA. Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein. Gastroenterology 2002;122:366-75
    • (2002) Gastroenterology , vol.122 , pp. 366-375
    • Okuda, M.1    Li, K.2    Beard, M.R.3    Showalter, L.A.4    Scholle, F.5    Lemon, S.M.6    Weinman, S.A.7
  • 29
    • 0031149589 scopus 로고    scopus 로고
    • Induction of smooth muscle cell phenotype in cultured human prostatic stromal cells
    • Peehl DM, Sellers RG. Induction of smooth muscle cell phenotype in cultured human prostatic stromal cells. Exp Cell Res 1997;232:208-15
    • (1997) Exp Cell Res , vol.232 , pp. 208-215
    • Peehl, D.M.1    Sellers, R.G.2
  • 30
    • 0033515099 scopus 로고    scopus 로고
    • Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat
    • Qi Z, Atsuchi N, Ooshima A, Takeshita A, Ueno H. Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat. Proc Natl Acad Sci USA 1999;96:2345-9
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2345-2349
    • Qi, Z.1    Atsuchi, N.2    Ooshima, A.3    Takeshita, A.4    Ueno, H.5
  • 31
    • 0036682952 scopus 로고    scopus 로고
    • Smad3 allostery links TGF-beta receptor kinase activation to transcriptional control
    • Qin BY, Lam SS, Correia JJ, Lin K. Smad3 allostery links TGF-beta receptor kinase activation to transcriptional control. Genes Dev 2002;16:1950-63
    • (2002) Genes Dev , vol.16 , pp. 1950-1963
    • Qin, B.Y.1    Lam, S.S.2    Correia, J.J.3    Lin, K.4
  • 32
    • 0042092032 scopus 로고    scopus 로고
    • Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis
    • Rachfal AW, Brigstock DR. Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis. Hepatol Res 2003;26:1-9
    • (2003) Hepatol Res , vol.26 , pp. 1-9
    • Rachfal, A.W.1    Brigstock, D.R.2
  • 33
    • 0031737792 scopus 로고    scopus 로고
    • Activation of rat hepatic stellate cells in culture is associated with increased sensitivity to endothelin 1
    • Reinehr RM, Kubitz R, Peters-Regehr T, Bode JG, Haussinger D. Activation of rat hepatic stellate cells in culture is associated with increased sensitivity to endothelin 1. Hepatology 1998;28:1566-77
    • (1998) Hepatology , vol.28 , pp. 1566-1577
    • Reinehr, R.M.1    Kubitz, R.2    Peters-Regehr, T.3    Bode, J.G.4    Haussinger, D.5
  • 40
    • 0342264463 scopus 로고    scopus 로고
    • Increased expression of connective tissue growth factor in fibrotic human liver and in activated hepatic stellate cells
    • Williams EJ, Gaca MD, Brigstock DR, Arthur MJ, Benyon RC. Increased expression of connective tissue growth factor in fibrotic human liver and in activated hepatic stellate cells. J Hepatol 2000;32:754-61
    • (2000) J Hepatol , vol.32 , pp. 754-761
    • Williams, E.J.1    Gaca, M.D.2    Brigstock, D.R.3    Arthur, M.J.4    Benyon, R.C.5
  • 41
    • 0013254477 scopus 로고    scopus 로고
    • Hepatitis C virus core inhibits the Fas-mediated p38 mitogen activated kinase signaling pathway in hepatocytes
    • Yang SH, Lee CG, Lee CW, Choi EJ, Yoon SK, Ahn KS, Sung YC. Hepatitis C virus core inhibits the Fas-mediated p38 mitogen activated kinase signaling pathway in hepatocytes. Mol Cells 2002;13:452-62
    • (2002) Mol Cells , vol.13 , pp. 452-462
    • Yang, S.H.1    Lee, C.G.2    Lee, C.W.3    Choi, E.J.4    Yoon, S.K.5    Ahn, K.S.6    Sung, Y.C.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.