메뉴 건너뛰기




Volumn 52, Issue 7, 2008, Pages 815-822

Comparison of delphinidin, quercetin and (-)-epigallocatechin-3-gallate as inhibitors of the EGFR and the ErbB2 receptor phosphorylation

Author keywords

A431; Autophosphorylation; Cellular signalling; ERK; HT29

Indexed keywords

ANTHOCYANIN; CATECHIN; DELPHINIDIN; DRUG DERIVATIVE; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIGALLOCATECHIN GALLATE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; QUERCETIN;

EID: 53249119839     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.200800026     Document Type: Article
Times cited : (58)

References (33)
  • 1
    • 33644827448 scopus 로고    scopus 로고
    • Apple flavonoids inhibit growth of HT29 human colon cancer cells and modulate expression of genes involved in the biotransformation of xenobiotics
    • Verriah, S., Kautenburger, T., Habermann, S., Sauer, J., et al., Apple flavonoids inhibit growth of HT29 human colon cancer cells and modulate expression of genes involved in the biotransformation of xenobiotics. Mol. Carcinog. 2006, 45, 164-174.
    • (2006) Mol. Carcinog , vol.45 , pp. 164-174
    • Verriah, S.1    Kautenburger, T.2    Habermann, S.3    Sauer, J.4
  • 2
    • 2442623486 scopus 로고    scopus 로고
    • The role of activated MEK-ERK pathway in quercetin-induced growth inhibition and apoptosis in A549 lung cancer cells
    • Nguyen, T. T., Tran, E., Nguyen, T. H., Do, P. T., et al., The role of activated MEK-ERK pathway in quercetin-induced growth inhibition and apoptosis in A549 lung cancer cells. Carcinogenesis 2004, 25, 647-659.
    • (2004) Carcinogenesis , vol.25 , pp. 647-659
    • Nguyen, T.T.1    Tran, E.2    Nguyen, T.H.3    Do, P.T.4
  • 3
    • 0031957897 scopus 로고    scopus 로고
    • Inhibition of epidermal growth factor receptor kinase induces protease-dependent apoptosis in human colon cancer cells
    • Karnes, W. E. Jr., Weller, S. G., Adjei, P. N., Kottke, T. J., et al., Inhibition of epidermal growth factor receptor kinase induces protease-dependent apoptosis in human colon cancer cells. Gastroenterology 1998, 114, 930-939.
    • (1998) Gastroenterology , vol.114 , pp. 930-939
    • Karnes Jr., W.E.1    Weller, S.G.2    Adjei, P.N.3    Kottke, T.J.4
  • 4
    • 0030930265 scopus 로고    scopus 로고
    • Suppression of extracellular signals and cell proliferation through EGF receptor binding by (-)-epigallocatechin gallate in human A431 epidermoid carcinoma cells
    • Liang, Y. C., Lin-Shiau, S. Y., Chen, C. F., Lin, J. K., Suppression of extracellular signals and cell proliferation through EGF receptor binding by (-)-epigallocatechin gallate in human A431 epidermoid carcinoma cells. J. Cell Biochem. 1997, 67, 55-65.
    • (1997) J. Cell Biochem , vol.67 , pp. 55-65
    • Liang, Y.C.1    Lin-Shiau, S.Y.2    Chen, C.F.3    Lin, J.K.4
  • 5
    • 0035114407 scopus 로고    scopus 로고
    • The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth factor receptor
    • Meiers, S., Kemény, M., Weyand, U., Gastpar, R., et al., The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth factor receptor. J. Agric. Food Chem. 2004, 49, 958-962.
    • (2004) J. Agric. Food Chem , vol.49 , pp. 958-962
    • Meiers, S.1    Kemény, M.2    Weyand, U.3    Gastpar, R.4
  • 6
    • 9944249485 scopus 로고    scopus 로고
    • The substitution pattern of anthocyanidins affects different cellular signaling cascades regulating cell proliferation
    • Marko, D., Puppel, N., Tjaden, Z., Jakobs, S., Pahlke, G., The substitution pattern of anthocyanidins affects different cellular signaling cascades regulating cell proliferation. Mol. Nutr. Food Res. 2004, 48, 318-325.
    • (2004) Mol. Nutr. Food Res , vol.48 , pp. 318-325
    • Marko, D.1    Puppel, N.2    Tjaden, Z.3    Jakobs, S.4    Pahlke, G.5
  • 7
    • 17444361922 scopus 로고    scopus 로고
    • Inhibitors of the epidermal growth factor receptor in apple juice extract
    • Kern, M., Tjaden, Z., Ngiewih, Y., Puppel, N., et al., Inhibitors of the epidermal growth factor receptor in apple juice extract, Mol. Nutr. Food Res. 2005, 49, 317-328.
    • (2005) Mol. Nutr. Food Res , vol.49 , pp. 317-328
    • Kern, M.1    Tjaden, Z.2    Ngiewih, Y.3    Puppel, N.4
  • 8
    • 0028170817 scopus 로고
    • Receptor protein tyrosine kinases and their signal transduction pathways
    • van der Geer, P., Hunter, T., Lindberg, R. A., Receptor protein tyrosine kinases and their signal transduction pathways. Ann. Rev. Cell Biol. 1994, 10, 251-337.
    • (1994) Ann. Rev. Cell Biol , vol.10 , pp. 251-337
    • van der Geer, P.1    Hunter, T.2    Lindberg, R.A.3
  • 10
    • 0034869825 scopus 로고    scopus 로고
    • The basic biology of HER2
    • Rubin, I., Yarden, Y., The basic biology of HER2, Ann. Oncol. 2001, 12, 3-8.
    • (2001) Ann. Oncol , vol.12 , pp. 3-8
    • Rubin, I.1    Yarden, Y.2
  • 11
    • 25844457433 scopus 로고    scopus 로고
    • The epidermal growth factor receptor family
    • Bazely, L. A., Gullick, W. J., The epidermal growth factor receptor family, Endocr. Relat. Canc. 2005, 12, 17-27.
    • (2005) Endocr. Relat. Canc , vol.12 , pp. 17-27
    • Bazely, L.A.1    Gullick, W.J.2
  • 12
    • 0034600849 scopus 로고    scopus 로고
    • The ErbB signalling network: Receptor heterodimerization in development and cancer
    • Olayioye, M. A., Neve, R. M., Lane, H. A., Hynes, N. E., The ErbB signalling network: Receptor heterodimerization in development and cancer. EMBO J. 2000, 19, 3159-3167.
    • (2000) EMBO J , vol.19 , pp. 3159-3167
    • Olayioye, M.A.1    Neve, R.M.2    Lane, H.A.3    Hynes, N.E.4
  • 13
    • 0034992521 scopus 로고    scopus 로고
    • The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification
    • Prenzel, N., Fischer, O. M., Streit, S., Hart, S., Ullrich, A., The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. Endocr. Relat. Canc. 2001, 8, 11-31.
    • (2001) Endocr. Relat. Canc , vol.8 , pp. 11-31
    • Prenzel, N.1    Fischer, O.M.2    Streit, S.3    Hart, S.4    Ullrich, A.5
  • 14
    • 0032999409 scopus 로고    scopus 로고
    • Molecules in focus: EGF receptor
    • Wells, A., Molecules in focus: EGF receptor. Int. J. Biochem. Cell Biol. 1999, 31, 637-643.
    • (1999) Int. J. Biochem. Cell Biol , vol.31 , pp. 637-643
    • Wells, A.1
  • 15
    • 0031705405 scopus 로고    scopus 로고
    • ErbB tyrosine kinases and the two neuregulin families constitute a ligand-receptor network
    • Pinkas-Kramarski, R., Shelly, M., Guarino, B. C., Wang, L. M., et al., ErbB tyrosine kinases and the two neuregulin families constitute a ligand-receptor network. Mol. Cell Biol. 1998, 18, 6090-6101.
    • (1998) Mol. Cell Biol , vol.18 , pp. 6090-6101
    • Pinkas-Kramarski, R.1    Shelly, M.2    Guarino, B.C.3    Wang, L.M.4
  • 16
    • 0037429737 scopus 로고    scopus 로고
    • Epidermal growth factor receptor: Mechanisms of activation and signaling
    • Jorissen, R. N., Walker, F., Pouliot, N., Garrett, T. P. J., et al., Epidermal growth factor receptor: mechanisms of activation and signaling. Exp. Cell Res. 2003, 284, 31-53.
    • (2003) Exp. Cell Res , vol.284 , pp. 31-53
    • Jorissen, R.N.1    Walker, F.2    Pouliot, N.3    Garrett, T.P.J.4
  • 17
    • 2142843806 scopus 로고    scopus 로고
    • Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions
    • Pinkas-Kramarski, R., Soussan, L., Waterman, H., Levkowitz, G., et al., Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions. EMBO J. 1996, 15, 2452-2467.
    • (1996) EMBO J , vol.15 , pp. 2452-2467
    • Pinkas-Kramarski, R.1    Soussan, L.2    Waterman, H.3    Levkowitz, G.4
  • 18
    • 0030919509 scopus 로고    scopus 로고
    • Neuregulins and their receptors: A versatile signaling module in organogenesis and oncogenesis
    • Burden, S., Yarden, Y., Neuregulins and their receptors: A versatile signaling module in organogenesis and oncogenesis. Neuron 1997, 18, 847-855.
    • (1997) Neuron , vol.18 , pp. 847-855
    • Burden, S.1    Yarden, Y.2
  • 19
    • 0029814271 scopus 로고    scopus 로고
    • A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor
    • Tzahar, E., Waterman, H., Chen, X., Levkowitz, G., et al., A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor. Mol. Cell Biol. 1996, 16, 5276-5287.
    • (1996) Mol. Cell Biol , vol.16 , pp. 5276-5287
    • Tzahar, E.1    Waterman, H.2    Chen, X.3    Levkowitz, G.4
  • 20
    • 0030030072 scopus 로고    scopus 로고
    • ErbB-2 is a common auxilary subunit of NDFand EGF receptors: Implications for breast cancer
    • Karunagaran, D., Tzahar, E., Beerli, R. R., Chen, X., et al., ErbB-2 is a common auxilary subunit of NDFand EGF receptors: Implications for breast cancer. EMBO J. 1996, 15, 254-264.
    • (1996) EMBO J , vol.15 , pp. 254-264
    • Karunagaran, D.1    Tzahar, E.2    Beerli, R.R.3    Chen, X.4
  • 21
    • 1842424851 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signalling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases
    • Sah, J. F., Balasubramanian, S., Eckert, R. L., Rorke, E. A., Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signalling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases. J. Biol. Chem. 2004, 279, 12755-12762.
    • (2004) J. Biol. Chem , vol.279 , pp. 12755-12762
    • Sah, J.F.1    Balasubramanian, S.2    Eckert, R.L.3    Rorke, E.A.4
  • 22
    • 34250897841 scopus 로고    scopus 로고
    • The epidermal growth factor receptor and human topoisomerases represent potential cellular targets of oligomeric procyanidins
    • Fridrich, D., Kern, M., Fritz, J., Pahlke, G., et al., The epidermal growth factor receptor and human topoisomerases represent potential cellular targets of oligomeric procyanidins. Mol. Nutr. Food Res. 2007, 51, 192-200.
    • (2007) Mol. Nutr. Food Res , vol.51 , pp. 192-200
    • Fridrich, D.1    Kern, M.2    Fritz, J.3    Pahlke, G.4
  • 23
    • 0036327836 scopus 로고    scopus 로고
    • Blockade of the epidermal growth factor receptor tyrosine kinase activity by quercetin and luteolin leads to growth inhibition and apoptosis of pancreatic tumor cells
    • Lee, L. T., Huang, Y. T., Hwang, J. J., Lee, P. P., et al., Blockade of the epidermal growth factor receptor tyrosine kinase activity by quercetin and luteolin leads to growth inhibition and apoptosis of pancreatic tumor cells. Anticancer Res. 2002, 22, 1615-1627.
    • (2002) Anticancer Res , vol.22 , pp. 1615-1627
    • Lee, L.T.1    Huang, Y.T.2    Hwang, J.J.3    Lee, P.P.4
  • 24
    • 0035226608 scopus 로고    scopus 로고
    • Differential responses of skin cancer-chemopreventive agents silibinin, quercetin, and epigallocatechin 3-gallate on mitogenic signaling and cell cycle regulators in human epidermoid carcinoma A431 cells
    • Bhatia, N., Agarwal, C., Agarwal, R., Differential responses of skin cancer-chemopreventive agents silibinin, quercetin, and epigallocatechin 3-gallate on mitogenic signaling and cell cycle regulators in human epidermoid carcinoma A431 cells. Nutr. Canc. 2001, 39, 292-299.
    • (2001) Nutr. Canc , vol.39 , pp. 292-299
    • Bhatia, N.1    Agarwal, C.2    Agarwal, R.3
  • 25
    • 21344457447 scopus 로고    scopus 로고
    • Synergy of epidermal growth factor receptor kinase inhibitor AG1478 and Erb2 kinase inhibitor AG879 in human colon carcinoma cells is associated with induction of apoptosis
    • Zhou, Y., Brattain, M. G., Synergy of epidermal growth factor receptor kinase inhibitor AG1478 and Erb2 kinase inhibitor AG879 in human colon carcinoma cells is associated with induction of apoptosis, Canc. Res., 2005, 65, 5848-5856.
    • (2005) Canc. Res , vol.65 , pp. 5848-5856
    • Zhou, Y.1    Brattain, M.G.2
  • 26
    • 33646247862 scopus 로고    scopus 로고
    • Biological activities of malvidin, a red wine anthocyanidin
    • Fritz, J., Kern, M., Pahlke, G., Vatter, S., Marko, D., Biological activities of malvidin, a red wine anthocyanidin, Mol. Nutr. Food Res. 2006, 50, 390-395.
    • (2006) Mol. Nutr. Food Res , vol.50 , pp. 390-395
    • Fritz, J.1    Kern, M.2    Pahlke, G.3    Vatter, S.4    Marko, D.5
  • 27
    • 22744444072 scopus 로고    scopus 로고
    • EGCG inhibits activation of the insulin-like growth factor-1 receptor in human colon cancer cells
    • Shimizu, M., Deguchi, A., Hara, Y., Moriwaki, H., Weinstein, I. B., EGCG inhibits activation of the insulin-like growth factor-1 receptor in human colon cancer cells. Biochem. Biophys. Res. Commun. 2005, 334, 947-953.
    • (2005) Biochem. Biophys. Res. Commun , vol.334 , pp. 947-953
    • Shimizu, M.1    Deguchi, A.2    Hara, Y.3    Moriwaki, H.4    Weinstein, I.B.5
  • 28
    • 33644523075 scopus 로고    scopus 로고
    • Ingested delphinidin-3-rutinoside is primarily excreted to urine as the intact form and to bile as the methylated form in rats
    • Matsumoto, H., Ichiyanagi, T., Iida, H., Ito, K., et al., Ingested delphinidin-3-rutinoside is primarily excreted to urine as the intact form and to bile as the methylated form in rats. J Agric Food Chem. 2006, 54, 578-582.
    • (2006) J Agric Food Chem , vol.54 , pp. 578-582
    • Matsumoto, H.1    Ichiyanagi, T.2    Iida, H.3    Ito, K.4
  • 29
    • 13844281685 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
    • Manach, C., Williamson, G., Morand, C., Scalbert, A., Rémésy, C., Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Am. J. Clin. Nutr. 2005, 81, 230-242.
    • (2005) Am. J. Clin. Nutr , vol.81 , pp. 230-242
    • Manach, C.1    Williamson, G.2    Morand, C.3    Scalbert, A.4    Rémésy, C.5
  • 30
    • 34447636817 scopus 로고    scopus 로고
    • Availability of blueberry phenolics for microbial metabolism in the colon and the potential inflammatory implications
    • Russell, W. R., Labalt, A., Scobbie, L., Duncan, S. H., Availability of blueberry phenolics for microbial metabolism in the colon and the potential inflammatory implications. Mol. Nutr. Food Res. 2007, 51, 726-731.
    • (2007) Mol. Nutr. Food Res , vol.51 , pp. 726-731
    • Russell, W.R.1    Labalt, A.2    Scobbie, L.3    Duncan, S.H.4
  • 31
    • 33644558720 scopus 로고    scopus 로고
    • Fate of anthocyanins and antioxidant capacity in contents of the gastrointestinal tract of weanling pigs following black raspberry consumption
    • Wu, X., Pittman, H. E., Prior, R. L., Fate of anthocyanins and antioxidant capacity in contents of the gastrointestinal tract of weanling pigs following black raspberry consumption. J. Agric. Food Chem. 2006, 54, 583-589.
    • (2006) J. Agric. Food Chem , vol.54 , pp. 583-589
    • Wu, X.1    Pittman, H.E.2    Prior, R.L.3
  • 32
    • 33646240144 scopus 로고    scopus 로고
    • Studies on apple and blueberry fruit constituents: Do the polyphenols reach the colon?
    • Kahle, K., Kraus, M., Scheppach, W., Ackermann, M., et al., Studies on apple and blueberry fruit constituents: Do the polyphenols reach the colon? Mol. Nutr. Food Res. 2006, 50, 418-423.
    • (2006) Mol. Nutr. Food Res , vol.50 , pp. 418-423
    • Kahle, K.1    Kraus, M.2    Scheppach, W.3    Ackermann, M.4
  • 33
    • 0141863400 scopus 로고    scopus 로고
    • Mechanisms of cancer prevention by tea constituents
    • Lambert, J. D., Yang, C. S., Mechanisms of cancer prevention by tea constituents. J. Nutr. 2003, 10, 3262-3267.
    • (2003) J. Nutr , vol.10 , pp. 3262-3267
    • Lambert, J.D.1    Yang, C.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.