메뉴 건너뛰기




Volumn 123, Issue 7, 2008, Pages 1508-1515

Inhibition of epidermal growth factor receptor signaling pathway by delphinidin, an anthocyanidin in pigmented fruits and vegetables

Author keywords

Apoptosis; Breast cancer; Delphinidin; Epidermal growth factor receptor; Mitogen activated protein kinases

Indexed keywords

ANTHOCYANIN; BETA ACTIN; CASPASE 3; DELPHINIDIN; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; SMALL INTERFERING RNA;

EID: 50549092185     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.23675     Document Type: Article
Times cited : (51)

References (29)
  • 1
    • 33745828702 scopus 로고    scopus 로고
    • EGF-ERBB signalling: Towards the systems level
    • Citri A, Yarden Y. EGF-ERBB signalling: towards the systems level. Nat Rev Mol Cell Biol 2006;7:505-16.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 505-516
    • Citri, A.1    Yarden, Y.2
  • 4
    • 33846566408 scopus 로고    scopus 로고
    • Dual inhibition of ErbB1 (EGFR/HER1) and ErbB2 (HER2/neu)
    • Reid A, Vidal L, Shaw H, de Bono J. Dual inhibition of ErbB1 (EGFR/HER1) and ErbB2 (HER2/neu). Eur J Cancer 2007;43:481-9.
    • (2007) Eur J Cancer , vol.43 , pp. 481-489
    • Reid, A.1    Vidal, L.2    Shaw, H.3    de Bono, J.4
  • 5
    • 2342591455 scopus 로고    scopus 로고
    • The discovery of receptor tyrosine kinases: Targets for cancer therapy
    • Gschwind A, Fischer OM, Ullrich A. The discovery of receptor tyrosine kinases: targets for cancer therapy. Nat Rev Cancer 2004;4:361-70.
    • (2004) Nat Rev Cancer , vol.4 , pp. 361-370
    • Gschwind, A.1    Fischer, O.M.2    Ullrich, A.3
  • 6
    • 0033392005 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibition in cancer therapy: Biology, rationale and preliminary clinical results
    • Huang SM, Harari PM. Epidermal growth factor receptor inhibition in cancer therapy: biology, rationale and preliminary clinical results. Invest New Drugs 1999;17:259-69.
    • (1999) Invest New Drugs , vol.17 , pp. 259-269
    • Huang, S.M.1    Harari, P.M.2
  • 7
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon DS, Brandt R, Ciardiello F, Normanno N. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 1995;19:183-232.
    • (1995) Crit Rev Oncol Hematol , vol.19 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Ciardiello, F.3    Normanno, N.4
  • 9
    • 0025690737 scopus 로고
    • Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: A mechanism for receptor transregulation
    • Goldman R, Levy RB, Peles E, Yarden Y. Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation. Biochemistry 1990;29:11024-8.
    • (1990) Biochemistry , vol.29 , pp. 11024-11028
    • Goldman, R.1    Levy, R.B.2    Peles, E.3    Yarden, Y.4
  • 10
    • 0037229076 scopus 로고    scopus 로고
    • Targeting the epidermal growth factor receptor in cancer: Apoptosis takes center stage
    • Kari C, Chan TO, Rocha de Quadros M, Rodeck U. Targeting the epidermal growth factor receptor in cancer: apoptosis takes center stage. Cancer Res 2003;63:1-5.
    • (2003) Cancer Res , vol.63 , pp. 1-5
    • Kari, C.1    Chan, T.O.2    Rocha de Quadros, M.3    Rodeck, U.4
  • 11
    • 0034644539 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 2000;103:211-25.
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 12
    • 26644449670 scopus 로고    scopus 로고
    • The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells
    • She QB, Solit DB, Ye Q, O'Reilly KE, Lobo J, Rosen N. The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells. Cancer Cell 2005;8:287-97.
    • (2005) Cancer Cell , vol.8 , pp. 287-297
    • She, Q.B.1    Solit, D.B.2    Ye, Q.3    O'Reilly, K.E.4    Lobo, J.5    Rosen, N.6
  • 13
    • 0034600849 scopus 로고    scopus 로고
    • The ErbB signaling network: Receptor heterodimerization in development and cancer
    • Olayioye MA, Neve RM, Lane HA, Hynes NE. The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J 2000;19:3159-67.
    • (2000) EMBO J , vol.19 , pp. 3159-3167
    • Olayioye, M.A.1    Neve, R.M.2    Lane, H.A.3    Hynes, N.E.4
  • 15
    • 17844372539 scopus 로고    scopus 로고
    • Critical update and emerging trends in epidermal growth factor receptor targeting in cancer
    • Baselga J, Arteaga CL. Critical update and emerging trends in epidermal growth factor receptor targeting in cancer. J Clin Oncol 2005;23:2445-59.
    • (2005) J Clin Oncol , vol.23 , pp. 2445-2459
    • Baselga, J.1    Arteaga, C.L.2
  • 16
    • 34247480545 scopus 로고    scopus 로고
    • Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition
    • Force T, Krause DS, Van Etten RA. Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition. Nat Rev Cancer 2007;7:332-44.
    • (2007) Nat Rev Cancer , vol.7 , pp. 332-344
    • Force, T.1    Krause, D.S.2    Van Etten, R.A.3
  • 17
    • 33845744294 scopus 로고    scopus 로고
    • Delphinidin, an anthocyanidin in pigmented fruits and vegetables, protects human HaCaT keratinocytes and mouse skin against UVB-mediated oxidative stress and apoptosis
    • Afaq F, Syed DN, Malik A, Hadi N, Sarfaraz S, Kweon MH, Khan N, Zaid MA, Mukhtar H. Delphinidin, an anthocyanidin in pigmented fruits and vegetables, protects human HaCaT keratinocytes and mouse skin against UVB-mediated oxidative stress and apoptosis. J Invest Dermatol 2007;127:222-32.
    • (2007) J Invest Dermatol , vol.127 , pp. 222-232
    • Afaq, F.1    Syed, D.N.2    Malik, A.3    Hadi, N.4    Sarfaraz, S.5    Kweon, M.H.6    Khan, N.7    Zaid, M.A.8    Mukhtar, H.9
  • 18
    • 33749032411 scopus 로고    scopus 로고
    • Delphinidin and cyanidin inhibit PDGF(AB)-induced VEGF release in vascular smooth muscle cells by preventing activation of p38 MAPK and JNK
    • Oak MH, Bedoui JE, Madeira SV, Chalupsky K, Schini-Kerth VB. Delphinidin and cyanidin inhibit PDGF(AB)-induced VEGF release in vascular smooth muscle cells by preventing activation of p38 MAPK and JNK. Br J Pharmacol 2006;149:283-90.
    • (2006) Br J Pharmacol , vol.149 , pp. 283-290
    • Oak, M.H.1    Bedoui, J.E.2    Madeira, S.V.3    Chalupsky, K.4    Schini-Kerth, V.B.5
  • 19
    • 33749242813 scopus 로고    scopus 로고
    • Superoxide radical- and peroxynitrite-scavenging activity of anthocyanins; structure-activity relationship and their synergism
    • Rahman MM, Ichiyanagi T, Komiyama T, Hatano Y, Konishi T. Superoxide radical- and peroxynitrite-scavenging activity of anthocyanins; structure-activity relationship and their synergism. Free Radic Res 2006;40:993-1002.
    • (2006) Free Radic Res , vol.40 , pp. 993-1002
    • Rahman, M.M.1    Ichiyanagi, T.2    Komiyama, T.3    Hatano, Y.4    Konishi, T.5
  • 20
    • 33646180698 scopus 로고    scopus 로고
    • Lamy S, Blanchette M, Michaud-Levesque J, Lafleur R, Durocher Y, Moghrabi A, Barrette S, Gingras D, Béliveau R. Delphinidin, a dietary anthocyanidin, inhibits vascular endothelial growth factor receptor-2 phosphorylation. Carcinogenesis 2006;27:989-96.
    • Lamy S, Blanchette M, Michaud-Levesque J, Lafleur R, Durocher Y, Moghrabi A, Barrette S, Gingras D, Béliveau R. Delphinidin, a dietary anthocyanidin, inhibits vascular endothelial growth factor receptor-2 phosphorylation. Carcinogenesis 2006;27:989-96.
  • 21
    • 0037441423 scopus 로고    scopus 로고
    • Delphinidin inhibits endothelial cell proliferation and cell cycle progression through a transient activation of ERK-1/-2
    • Martin S, Favot L, Matz R, Lugnier C, Andriantsitohaina R. Delphinidin inhibits endothelial cell proliferation and cell cycle progression through a transient activation of ERK-1/-2. Biochem Pharmacol 2003;65:669-75.
    • (2003) Biochem Pharmacol , vol.65 , pp. 669-675
    • Martin, S.1    Favot, L.2    Matz, R.3    Lugnier, C.4    Andriantsitohaina, R.5
  • 22
    • 0036362181 scopus 로고    scopus 로고
    • Why the epidermal growth factor receptor? The rationale for cancer therapy
    • Baselga J. Why the epidermal growth factor receptor? The rationale for cancer therapy. Oncologist 2002;7 (Suppl 4):2-8.
    • (2002) Oncologist , vol.7 , Issue.SUPPL. 4 , pp. 2-8
    • Baselga, J.1
  • 23
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 25
    • 33846685893 scopus 로고    scopus 로고
    • Bortezomib inhibits cell-cell adhesion and cell migration and enhances epidermal growth factor receptor inhibitor-induced cell death in squamous cell cancer
    • Lorch JH, Thomas TO, Schmoll HJ. Bortezomib inhibits cell-cell adhesion and cell migration and enhances epidermal growth factor receptor inhibitor-induced cell death in squamous cell cancer. Cancer Res 2007;67:727-34.
    • (2007) Cancer Res , vol.67 , pp. 727-734
    • Lorch, J.H.1    Thomas, T.O.2    Schmoll, H.J.3
  • 27
    • 33847284555 scopus 로고    scopus 로고
    • Apoptosis by dietary factors: The suicide solution for delaying cancer growth
    • Khan N, Afaq F, Mukhtar H. Apoptosis by dietary factors: the suicide solution for delaying cancer growth. Carcinogenesis 2007;28:233-9.
    • (2007) Carcinogenesis , vol.28 , pp. 233-239
    • Khan, N.1    Afaq, F.2    Mukhtar, H.3
  • 28
    • 28544443984 scopus 로고    scopus 로고
    • Promoting apoptosis as a strategy for cancer drug discovery
    • Fesik SW. Promoting apoptosis as a strategy for cancer drug discovery. Nat Rev Cancer 2005;5:876-85.
    • (2005) Nat Rev Cancer , vol.5 , pp. 876-885
    • Fesik, S.W.1
  • 29
    • 34648816362 scopus 로고    scopus 로고
    • Induction of cell cycle arrest and apoptosis in human nasopharyngeal carcinoma cells by ZD6474, an inhibitor of VEGFR tyrosine kinase with additional activity against EGFR tyrosine kinase
    • Xiao X, Wu J, Zhu X, Zhao P, Zhou J, Liu QQ, Zheng L, Zeng M, Liu R, Huang W. Induction of cell cycle arrest and apoptosis in human nasopharyngeal carcinoma cells by ZD6474, an inhibitor of VEGFR tyrosine kinase with additional activity against EGFR tyrosine kinase. Int J Cancer 2007;121:2095-104.
    • (2007) Int J Cancer , vol.121 , pp. 2095-2104
    • Xiao, X.1    Wu, J.2    Zhu, X.3    Zhao, P.4    Zhou, J.5    Liu, Q.Q.6    Zheng, L.7    Zeng, M.8    Liu, R.9    Huang, W.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.