-
1
-
-
33745828702
-
EGF-ERBB signalling: Towards the systems level
-
Citri A, Yarden Y. EGF-ERBB signalling: towards the systems level. Nat Rev Mol Cell Biol 2006;7:505-16.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 505-516
-
-
Citri, A.1
Yarden, Y.2
-
2
-
-
32044464123
-
Epidermal growth factor receptor (EGFR) signaling in cancer
-
Normanno N, De Luca A, Bianco C, Strizzi L, Mancino M, Maiello MR, Carotenuto A, De Feo G, Caponigro F, Salomon DS. Epidermal growth factor receptor (EGFR) signaling in cancer. Gene 2006;366:2-16.
-
(2006)
Gene
, vol.366
, pp. 2-16
-
-
Normanno, N.1
De Luca, A.2
Bianco, C.3
Strizzi, L.4
Mancino, M.5
Maiello, M.R.6
Carotenuto, A.7
De Feo, G.8
Caponigro, F.9
Salomon, D.S.10
-
4
-
-
33846566408
-
Dual inhibition of ErbB1 (EGFR/HER1) and ErbB2 (HER2/neu)
-
Reid A, Vidal L, Shaw H, de Bono J. Dual inhibition of ErbB1 (EGFR/HER1) and ErbB2 (HER2/neu). Eur J Cancer 2007;43:481-9.
-
(2007)
Eur J Cancer
, vol.43
, pp. 481-489
-
-
Reid, A.1
Vidal, L.2
Shaw, H.3
de Bono, J.4
-
5
-
-
2342591455
-
The discovery of receptor tyrosine kinases: Targets for cancer therapy
-
Gschwind A, Fischer OM, Ullrich A. The discovery of receptor tyrosine kinases: targets for cancer therapy. Nat Rev Cancer 2004;4:361-70.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 361-370
-
-
Gschwind, A.1
Fischer, O.M.2
Ullrich, A.3
-
6
-
-
0033392005
-
Epidermal growth factor receptor inhibition in cancer therapy: Biology, rationale and preliminary clinical results
-
Huang SM, Harari PM. Epidermal growth factor receptor inhibition in cancer therapy: biology, rationale and preliminary clinical results. Invest New Drugs 1999;17:259-69.
-
(1999)
Invest New Drugs
, vol.17
, pp. 259-269
-
-
Huang, S.M.1
Harari, P.M.2
-
7
-
-
0028955388
-
Epidermal growth factor-related peptides and their receptors in human malignancies
-
Salomon DS, Brandt R, Ciardiello F, Normanno N. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 1995;19:183-232.
-
(1995)
Crit Rev Oncol Hematol
, vol.19
, pp. 183-232
-
-
Salomon, D.S.1
Brandt, R.2
Ciardiello, F.3
Normanno, N.4
-
8
-
-
7944221151
-
Expression and co-expression of the members of the epidermal growth factor receptor (EGFR) family in invasive breast carcinoma
-
Abd El-Rehim DM, Pinder SE, Paish CE, Bell JA, Rampaul RS, Blamey RW, Robertson JF, Nicholson RI, Ellis IO. Expression and co-expression of the members of the epidermal growth factor receptor (EGFR) family in invasive breast carcinoma. Br J Cancer 2004;91:1532-42.
-
(2004)
Br J Cancer
, vol.91
, pp. 1532-1542
-
-
Abd El-Rehim, D.M.1
Pinder, S.E.2
Paish, C.E.3
Bell, J.A.4
Rampaul, R.S.5
Blamey, R.W.6
Robertson, J.F.7
Nicholson, R.I.8
Ellis, I.O.9
-
9
-
-
0025690737
-
Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: A mechanism for receptor transregulation
-
Goldman R, Levy RB, Peles E, Yarden Y. Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation. Biochemistry 1990;29:11024-8.
-
(1990)
Biochemistry
, vol.29
, pp. 11024-11028
-
-
Goldman, R.1
Levy, R.B.2
Peles, E.3
Yarden, Y.4
-
10
-
-
0037229076
-
Targeting the epidermal growth factor receptor in cancer: Apoptosis takes center stage
-
Kari C, Chan TO, Rocha de Quadros M, Rodeck U. Targeting the epidermal growth factor receptor in cancer: apoptosis takes center stage. Cancer Res 2003;63:1-5.
-
(2003)
Cancer Res
, vol.63
, pp. 1-5
-
-
Kari, C.1
Chan, T.O.2
Rocha de Quadros, M.3
Rodeck, U.4
-
11
-
-
0034644539
-
Cell signaling by receptor tyrosine kinases
-
Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 2000;103:211-25.
-
(2000)
Cell
, vol.103
, pp. 211-225
-
-
Schlessinger, J.1
-
12
-
-
26644449670
-
The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells
-
She QB, Solit DB, Ye Q, O'Reilly KE, Lobo J, Rosen N. The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells. Cancer Cell 2005;8:287-97.
-
(2005)
Cancer Cell
, vol.8
, pp. 287-297
-
-
She, Q.B.1
Solit, D.B.2
Ye, Q.3
O'Reilly, K.E.4
Lobo, J.5
Rosen, N.6
-
13
-
-
0034600849
-
The ErbB signaling network: Receptor heterodimerization in development and cancer
-
Olayioye MA, Neve RM, Lane HA, Hynes NE. The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J 2000;19:3159-67.
-
(2000)
EMBO J
, vol.19
, pp. 3159-3167
-
-
Olayioye, M.A.1
Neve, R.M.2
Lane, H.A.3
Hynes, N.E.4
-
14
-
-
0023812036
-
Predictive value of EGF receptor in breast cancer
-
Costa S, Stamm H, Almendral A, Ludwig H, Wyss R, Fabbro D, Ernst A, Takahashi A, Eppenberger U. Predictive value of EGF receptor in breast cancer. Lancet 1988;2:1258.
-
(1988)
Lancet
, vol.2
, pp. 1258
-
-
Costa, S.1
Stamm, H.2
Almendral, A.3
Ludwig, H.4
Wyss, R.5
Fabbro, D.6
Ernst, A.7
Takahashi, A.8
Eppenberger, U.9
-
15
-
-
17844372539
-
Critical update and emerging trends in epidermal growth factor receptor targeting in cancer
-
Baselga J, Arteaga CL. Critical update and emerging trends in epidermal growth factor receptor targeting in cancer. J Clin Oncol 2005;23:2445-59.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2445-2459
-
-
Baselga, J.1
Arteaga, C.L.2
-
16
-
-
34247480545
-
Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition
-
Force T, Krause DS, Van Etten RA. Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition. Nat Rev Cancer 2007;7:332-44.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 332-344
-
-
Force, T.1
Krause, D.S.2
Van Etten, R.A.3
-
17
-
-
33845744294
-
Delphinidin, an anthocyanidin in pigmented fruits and vegetables, protects human HaCaT keratinocytes and mouse skin against UVB-mediated oxidative stress and apoptosis
-
Afaq F, Syed DN, Malik A, Hadi N, Sarfaraz S, Kweon MH, Khan N, Zaid MA, Mukhtar H. Delphinidin, an anthocyanidin in pigmented fruits and vegetables, protects human HaCaT keratinocytes and mouse skin against UVB-mediated oxidative stress and apoptosis. J Invest Dermatol 2007;127:222-32.
-
(2007)
J Invest Dermatol
, vol.127
, pp. 222-232
-
-
Afaq, F.1
Syed, D.N.2
Malik, A.3
Hadi, N.4
Sarfaraz, S.5
Kweon, M.H.6
Khan, N.7
Zaid, M.A.8
Mukhtar, H.9
-
18
-
-
33749032411
-
Delphinidin and cyanidin inhibit PDGF(AB)-induced VEGF release in vascular smooth muscle cells by preventing activation of p38 MAPK and JNK
-
Oak MH, Bedoui JE, Madeira SV, Chalupsky K, Schini-Kerth VB. Delphinidin and cyanidin inhibit PDGF(AB)-induced VEGF release in vascular smooth muscle cells by preventing activation of p38 MAPK and JNK. Br J Pharmacol 2006;149:283-90.
-
(2006)
Br J Pharmacol
, vol.149
, pp. 283-290
-
-
Oak, M.H.1
Bedoui, J.E.2
Madeira, S.V.3
Chalupsky, K.4
Schini-Kerth, V.B.5
-
19
-
-
33749242813
-
Superoxide radical- and peroxynitrite-scavenging activity of anthocyanins; structure-activity relationship and their synergism
-
Rahman MM, Ichiyanagi T, Komiyama T, Hatano Y, Konishi T. Superoxide radical- and peroxynitrite-scavenging activity of anthocyanins; structure-activity relationship and their synergism. Free Radic Res 2006;40:993-1002.
-
(2006)
Free Radic Res
, vol.40
, pp. 993-1002
-
-
Rahman, M.M.1
Ichiyanagi, T.2
Komiyama, T.3
Hatano, Y.4
Konishi, T.5
-
20
-
-
33646180698
-
-
Lamy S, Blanchette M, Michaud-Levesque J, Lafleur R, Durocher Y, Moghrabi A, Barrette S, Gingras D, Béliveau R. Delphinidin, a dietary anthocyanidin, inhibits vascular endothelial growth factor receptor-2 phosphorylation. Carcinogenesis 2006;27:989-96.
-
Lamy S, Blanchette M, Michaud-Levesque J, Lafleur R, Durocher Y, Moghrabi A, Barrette S, Gingras D, Béliveau R. Delphinidin, a dietary anthocyanidin, inhibits vascular endothelial growth factor receptor-2 phosphorylation. Carcinogenesis 2006;27:989-96.
-
-
-
-
21
-
-
0037441423
-
Delphinidin inhibits endothelial cell proliferation and cell cycle progression through a transient activation of ERK-1/-2
-
Martin S, Favot L, Matz R, Lugnier C, Andriantsitohaina R. Delphinidin inhibits endothelial cell proliferation and cell cycle progression through a transient activation of ERK-1/-2. Biochem Pharmacol 2003;65:669-75.
-
(2003)
Biochem Pharmacol
, vol.65
, pp. 669-675
-
-
Martin, S.1
Favot, L.2
Matz, R.3
Lugnier, C.4
Andriantsitohaina, R.5
-
22
-
-
0036362181
-
Why the epidermal growth factor receptor? The rationale for cancer therapy
-
Baselga J. Why the epidermal growth factor receptor? The rationale for cancer therapy. Oncologist 2002;7 (Suppl 4):2-8.
-
(2002)
Oncologist
, vol.7
, Issue.SUPPL. 4
, pp. 2-8
-
-
Baselga, J.1
-
23
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
24
-
-
32044466838
-
Exploiting the PI3K/AKT pathway for cancer drug discovery
-
Hennessy BT, Smith DL, Ram PT, Lu Y, Mills GB. Exploiting the PI3K/AKT pathway for cancer drug discovery. Nat Rev Drug Discov 2005;4:988-1004.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 988-1004
-
-
Hennessy, B.T.1
Smith, D.L.2
Ram, P.T.3
Lu, Y.4
Mills, G.B.5
-
25
-
-
33846685893
-
Bortezomib inhibits cell-cell adhesion and cell migration and enhances epidermal growth factor receptor inhibitor-induced cell death in squamous cell cancer
-
Lorch JH, Thomas TO, Schmoll HJ. Bortezomib inhibits cell-cell adhesion and cell migration and enhances epidermal growth factor receptor inhibitor-induced cell death in squamous cell cancer. Cancer Res 2007;67:727-34.
-
(2007)
Cancer Res
, vol.67
, pp. 727-734
-
-
Lorch, J.H.1
Thomas, T.O.2
Schmoll, H.J.3
-
26
-
-
34447538483
-
Cellular characterization of a novel focal adhesion kinase inhibitor
-
Slack-Davis JK, Martin KH, Tilghman RW, Iwanicki M, Ung EJ, Autry C, Luzzio MJ, Cooper B, Kath JC, Roberts WG, Parsons JT. Cellular characterization of a novel focal adhesion kinase inhibitor. J Biol Chem 2007;282:14845-52.
-
(2007)
J Biol Chem
, vol.282
, pp. 14845-14852
-
-
Slack-Davis, J.K.1
Martin, K.H.2
Tilghman, R.W.3
Iwanicki, M.4
Ung, E.J.5
Autry, C.6
Luzzio, M.J.7
Cooper, B.8
Kath, J.C.9
Roberts, W.G.10
Parsons, J.T.11
-
27
-
-
33847284555
-
Apoptosis by dietary factors: The suicide solution for delaying cancer growth
-
Khan N, Afaq F, Mukhtar H. Apoptosis by dietary factors: the suicide solution for delaying cancer growth. Carcinogenesis 2007;28:233-9.
-
(2007)
Carcinogenesis
, vol.28
, pp. 233-239
-
-
Khan, N.1
Afaq, F.2
Mukhtar, H.3
-
28
-
-
28544443984
-
Promoting apoptosis as a strategy for cancer drug discovery
-
Fesik SW. Promoting apoptosis as a strategy for cancer drug discovery. Nat Rev Cancer 2005;5:876-85.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 876-885
-
-
Fesik, S.W.1
-
29
-
-
34648816362
-
Induction of cell cycle arrest and apoptosis in human nasopharyngeal carcinoma cells by ZD6474, an inhibitor of VEGFR tyrosine kinase with additional activity against EGFR tyrosine kinase
-
Xiao X, Wu J, Zhu X, Zhao P, Zhou J, Liu QQ, Zheng L, Zeng M, Liu R, Huang W. Induction of cell cycle arrest and apoptosis in human nasopharyngeal carcinoma cells by ZD6474, an inhibitor of VEGFR tyrosine kinase with additional activity against EGFR tyrosine kinase. Int J Cancer 2007;121:2095-104.
-
(2007)
Int J Cancer
, vol.121
, pp. 2095-2104
-
-
Xiao, X.1
Wu, J.2
Zhu, X.3
Zhao, P.4
Zhou, J.5
Liu, Q.Q.6
Zheng, L.7
Zeng, M.8
Liu, R.9
Huang, W.10
|