Identification of hydrolytically stable and selective P2Y1 receptor agonists

European Journal of Medicinal Chemistry

Volumn 44, Issue 4, 2009, Pages 1525-1536

  Eliahu, Shay E ^a   Camden, Jean ^b   Lecka, Joanna ^c   Weisman, Gary A ^b   Sévigny, Jean ^c   Gélinas, Sylvie ^d   Fischer, Bilha ^a  

^a BAR ILAN UNIVERSITY   (Israel)

^b University of Missouri   (United States)

^c LAVAL UNIVERSITY   (Canada)

^d Innodia Inc   (Canada)

Author keywords

NPP; NTPDase; Nucleotides; P2Y1 2 4 6 receptor

Indexed keywords

ADENOSINE TRIPHOSPHATE DERIVATIVE; ALKALINE PHOSPHATASE; NUCLEOSIDE TRIPHOSPHATE; NUCLEOTIDE PYROPHOSPHATASE; PURINERGIC P2Y1 RECEPTOR; PURINERGIC RECEPTOR STIMULATING AGENT;

ARTICLE; ASTROCYTOMA CELL; BLOOD; CONTROLLED STUDY; DRUG HALF LIFE; DRUG HYDROLYSIS; DRUG RETENTION; DRUG STABILITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; STOMACH PH;

ADENOSINE TRIPHOSPHATASES; ANIMALS; BIOMIMETICS; CELL LINE, TUMOR; DRUG DESIGN; GASTRIC JUICE; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; NUCLEOTIDES; PURINERGIC P2 RECEPTOR AGONISTS; RECEPTORS, PURINERGIC P2Y1; SUBSTRATE SPECIFICITY; TEMPERATURE;

EID: 61349140591     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.07.015     Document Type: Article

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