Adenosine 5′-O-(1-boranotriphosphate) derivatives as novel P2Y1 receptor agonists

Journal of Medicinal Chemistry

Volumn 45, Issue 24, 2002, Pages 5384-5396

  Nahum, Victoria ^a   Zündorf, Gregor ^b   Lévesque, Sébastien A ^c   Beaudoin, Adrien R ^c   Reiser, Georg ^b   Fischer, Bilha ^a  

^a BAR ILAN UNIVERSITY   (Israel)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c UNIVERSITÉ DE SHERBROOKE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DERIVATIVE; ADENOSINE TRIPHOSPHATE; CALCIUM; NUCLEOTIDE DERIVATIVE; PURINE P2Y RECEPTOR; PURINE P2Y RECEPTOR AGONIST; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATASE; APYRASE; BORANE DERIVATIVE; CD39 ANTIGEN; LEUKOCYTE ANTIGEN; ORGANOPHOSPHORUS COMPOUND; PURINE P2 RECEPTOR; PURINE P2Y1 RECEPTOR;

ANIMAL TISSUE; ARTICLE; BRAIN; CALCIUM TRANSPORT; CELL STRAIN; CONTROLLED STUDY; DIASTEREOISOMER; DRUG POTENCY; DRUG STABILITY; DRUG SYNTHESIS; EMBRYO; ENZYME ANALYSIS; ENZYME STABILITY; ENZYME SUBSTRATE; GENETIC TRANSFECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROLYSIS; NONHUMAN; PH; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SPLEEN; STOMACH JUICE; CELL LINE; CHEMISTRY; DRUG POTENTIATION; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ADENOSINE TRIPHOSPHATASES; ANTIGENS, CD; APYRASE; BORANES; CALCIUM; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; GASTRIC JUICE; HUMANS; HYDROLYSIS; MAGNETIC RESONANCE SPECTROSCOPY; ORGANOPHOSPHORUS COMPOUNDS; RECEPTORS, PURINERGIC P2; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037153218     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020251d     Document Type: Article

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